DNA Damage-induced Heterogeneous Nuclear Ribonucleoprotein K SUMOylation Regulates p53 Transcriptional Activation

Proteomic Investigations Reveal a Role for RNA Processing Factor THRAP3 in the DNA Damage Response

(2012) Petra Beli et al.   MOLECULAR CELL

The RanBP2/RanGAP1∗SUMO1/Ubc9 Complex Is a Multisubunit SUMO E3 Ligase

(2012) Andreas Werner et al.   MOLECULAR CELL

ncRNA- and Pc2 Methylation-Dependent Gene Relocation between Nuclear Structures Mediates Gene Activation Programs

(2011) Liuqing Yang et al.   CELL

Essential role for the interaction between hnRNP H/F and a G quadruplex in maintaining p53 pre-mRNA 3'-end processing and function during DNA damage

(2011) A. Decorsiere et al.   GENES & DEVELOPMENT

A Large Intergenic Noncoding RNA Induced by p53 Mediates Global Gene Repression in the p53 Response

(2010) Maite Huarte et al.   CELL

SUMO functions in constitutive transcription and during activation of inducible genes in yeast

(2010) E. Rosonina et al.   GENES & DEVELOPMENT

The SUMO E3 Ligase Activity of Pc2 Is Coordinated through a SUMO Interaction Motif

(2010) S. h. Yang et al.   MOLECULAR AND CELLULAR BIOLOGY

SUMO-Specific Protease 2 Is Essential for Suppression of Polycomb Group Protein-Mediated Gene Silencing during Embryonic Development

(2010) Xunlei Kang et al.   MOLECULAR CELL

Regulation of DNA Repair through DeSUMOylation and SUMOylation of Replication Protein A Complex

(2010) Hong Dou et al.   MOLECULAR CELL

Regulation of p53 activity by HIPK2: molecular mechanisms and therapeutical implications in human cancer cells

(2010) R Puca et al.   ONCOGENE

A Role for Non-Covalent SUMO Interaction Motifs in Pc2/CBX4 E3 Activity

(2010) Jacqueline C. Merrill et al.   PLoS One

The serine/arginine-rich protein SF2/ASF regulates protein sumoylation

(2010) F. Pelisch et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Transcriptional Regulation by P53

(2010) R. Beckerman et al.   Cold Spring Harbor Perspectives in Biology

RING Domain E3 Ubiquitin Ligases

(2009) Raymond J. Deshaies et al.   Annual Review of Biochemistry

SUMO association with repressor complexes, emerging routes for transcriptional control

(2009) Mario Garcia-Dominguez et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

MDM2-Dependent Downregulation of p21 and hnRNP K Provides a Switch between Apoptosis and Growth Arrest Induced by Pharmacologically Activated p53

(2009) Martin Enge et al.   CANCER CELL

HIPK2 Regulation by MDM2 Determines Tumor Cell Response to the p53-Reactivating Drugs Nutlin-3 and RITA

(2009) C. Rinaldo et al.   CANCER RESEARCH

Blinded by the Light: The Growing Complexity of p53

(2009) Karen H. Vousden et al.   CELL

Extracellular Signal-Regulated Kinase Mitogen-Activated Protein Kinase Signaling Initiates a Dynamic Interplay between Sumoylation and Ubiquitination To Regulate the Activity of the Transcriptional Activator PEA3

(2009) B. Guo et al.   MOLECULAR AND CELLULAR BIOLOGY

Structure of the Siz/PIAS SUMO E3 Ligase Siz1 and Determinants Required for SUMO Modification of PCNA

(2009) Ali A. Yunus et al.   MOLECULAR CELL

The SUMO modification pathway is involved in the BRCA1 response to genotoxic stress

(2009) Joanna R. Morris et al.   NATURE

Mammalian SUMO E3-ligases PIAS1 and PIAS4 promote responses to DNA double-strand breaks

(2009) Yaron Galanty et al.   NATURE

Principles of ubiquitin and SUMO modifications in DNA repair

(2009) Steven Bergink et al.   NATURE

Detection of protein SUMOylation in vivo

(2009) Michael H Tatham et al.   Nature Protocols

Systematic study of protein sumoylation: Development of a site-specific predictor of SUMOsp 2.0

(2009) Jian Ren et al.   PROTEOMICS

The HECT Family of E3 Ubiquitin Ligases: Multiple Players in Cancer Development

(2008) Francesca Bernassola et al.   CANCER CELL