标题
Viral infections in type 1 diabetes mellitus — why the β cells?
作者
关键词
-
出版物
Nature Reviews Endocrinology
Volume 12, Issue 5, Pages 263-273
出版商
Springer Nature
发表日期
2016-03-29
DOI
10.1038/nrendo.2016.30
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Persistent infection of human pancreatic cells with Coxsackievirus B4 is cured by fluoxetine
- (2015) Enagnon Kazali Alidjinou et al. ANTIVIRAL RESEARCH
- The gut microbiota and Type 1 Diabetes
- (2015) Elke Gülden et al. CLINICAL IMMUNOLOGY
- TYK2, a Candidate Gene for Type 1 Diabetes, Modulates Apoptosis and the Innate Immune Response in Human Pancreatic β-Cells
- (2015) Laura Marroqui et al. DIABETES
- Function of Isolated Pancreatic Islets From Patients at Onset of Type 1 Diabetes: Insulin Secretion Can Be Restored After Some Days in a Nondiabetogenic Environment In Vitro
- (2015) Lars Krogvold et al. DIABETES
- Insulitis and β-Cell Mass in the Natural History of Type 1 Diabetes
- (2015) Martha Campbell-Thompson et al. DIABETES
- Reduced Expression of the MDA5 GeneIFIH1Prevents Autoimmune Diabetes
- (2015) Pamela J. Lincez et al. DIABETES
- Current Concepts on the Pathogenesis of Type 1 Diabetes—Considerations for Attempts to Prevent and Reverse the Disease
- (2015) Mark A. Atkinson et al. DIABETES CARE
- Lessons from the mouse: potential contribution of bystander lymphocyte activation by viruses to human type 1 diabetes
- (2015) Jessica A. Pane et al. DIABETOLOGIA
- The 6 year incidence of diabetes-associated autoantibodies in genetically at-risk children: the TEDDY study
- (2015) Jeffrey P. Krischer et al. DIABETOLOGIA
- Non-HLA gene effects on the disease process of type 1 diabetes: From HLA susceptibility to overt disease
- (2015) Johanna Lempainen et al. JOURNAL OF AUTOIMMUNITY
- Fine mapping of type 1 diabetes susceptibility loci and evidence for colocalization of causal variants with lymphoid gene enhancers
- (2015) Suna Onengut-Gumuscu et al. NATURE GENETICS
- Early IFN type I response: Learning from microbial evasion strategies
- (2015) Eliana M. Coccia et al. SEMINARS IN IMMUNOLOGY
- Recent progress in understanding coxsackievirus replication, dissemination, and pathogenesis
- (2015) Jon Sin et al. VIROLOGY
- Interferon therapy in hepatitis C leading to chronic type 1 diabetes
- (2015) Taiba Zornitzki WORLD JOURNAL OF GASTROENTEROLOGY
- Reduced Tyk2 gene expression in β-cells due to natural mutation determines susceptibility to virus-induced diabetes
- (2015) Kenichi Izumi et al. Nature Communications
- Differential cell autonomous responses determine the outcome of coxsackievirus infections in murine pancreatic α and β cells
- (2015) Laura Marroqui et al. eLife
- TYK2 Promoter Variant and Diabetes Mellitus in the Japanese
- (2015) Seiho Nagafuchi et al. EBioMedicine
- Pancreatic α Cells are Resistant to Metabolic Stress-induced Apoptosis in Type 2 Diabetes
- (2015) Laura Marroqui et al. EBioMedicine
- BACH2, a Candidate Risk Gene for Type 1 Diabetes, Regulates Apoptosis in Pancreatic -Cells via JNK1 Modulation and Crosstalk With the Candidate Gene PTPN2
- (2014) L. Marroqui et al. DIABETES
- Viral Infection of Engrafted Human Islets Leads to Diabetes
- (2014) Glen R. Gallagher et al. DIABETES
- Detection of a Low-Grade Enteroviral Infection in the Islets of Langerhans of Living Patients Newly Diagnosed With Type 1 Diabetes
- (2014) Lars Krogvold et al. DIABETES
- Molecular Signatures Differentiate Immune States in Type 1 Diabetic Families
- (2014) Yi-Guang Chen et al. DIABETES
- A Type I Interferon Transcriptional Signature Precedes Autoimmunity in Children Genetically at Risk for Type 1 Diabetes
- (2014) R. C. Ferreira et al. DIABETES
- Potential viral pathogenic mechanism in human type 1 diabetes
- (2014) Darius A. Schneider et al. DIABETOLOGIA
- A preclinical study on the efficacy and safety of a new vaccine against Coxsackievirus B1 reveals no risk for accelerated diabetes development in mouse models
- (2014) Pär G. Larsson et al. DIABETOLOGIA
- Pancreatic Pathology in Type 1 Diabetes Mellitus
- (2014) Sarah J. Richardson et al. ENDOCRINE PATHOLOGY
- Developing a vaccine for Type 1 diabetes through targeting enteroviral infections
- (2014) Heikki Hyöty et al. Expert Review of Vaccines
- Role of Viruses and Other Microbes in the Pathogenesis of Type 1 Diabetes
- (2014) Anita Kondrashova et al. INTERNATIONAL REVIEWS OF IMMUNOLOGY
- Coxsackievirus can persist in murine pancreas by deletion of 5′ terminal genomic sequences
- (2014) Steven Tracy et al. JOURNAL OF MEDICAL VIROLOGY
- Microbiology: Ditch the term pathogen
- (2014) Arturo Casadevall et al. NATURE
- Genetic and epigenetic fine mapping of causal autoimmune disease variants
- (2014) Kyle Kai-How Farh et al. NATURE
- CTSH regulates -cell function and disease progression in newly diagnosed type 1 diabetes patients
- (2014) T. Floyel et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Enteroviruses, hygiene and type 1 diabetes: toward a preventive vaccine
- (2014) Kristen M. Drescher et al. REVIEWS IN MEDICAL VIROLOGY
- Enteroviruses as causative agents in type 1 diabetes: loose ends or lost cause?
- (2014) Noel G. Morgan et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
- A strategy to find gene combinations that identify children who progress rapidly to type 1 diabetes after islet autoantibody seroconversion
- (2013) Ezio Bonifacio et al. ACTA DIABETOLOGICA
- Deficiency in Type I Interferon Signaling Prevents the Early Interferon-Induced Gene Signature in Pancreatic Islets but Not Type 1 Diabetes in NOD Mice
- (2013) H. S. Quah et al. DIABETES
- RNA Sequencing Identifies Dysregulation of the Human Pancreatic Islet Transcriptome by the Saturated Fatty Acid Palmitate
- (2013) Miriam Cnop et al. DIABETES
- Virus Antibody Survey in Different European Populations Indicates Risk Association Between Coxsackievirus B1 and Type 1 Diabetes
- (2013) S. Oikarinen et al. DIABETES
- Patterns of -Cell Autoantibody Appearance and Genetic Associations During the First Years of Life
- (2013) J. Ilonen et al. DIABETES
- Coxsackievirus B1 Is Associated With Induction of -Cell Autoimmunity That Portends Type 1 Diabetes
- (2013) O. H. Laitinen et al. DIABETES
- Candidate genes for type 1 diabetes modulate pancreatic islet inflammation andβ-cell apoptosis
- (2013) I. Santin et al. DIABETES OBESITY & METABOLISM
- Pathophysiological mechanisms involving aggressive islet cell destruction in fulminant type 1 diabetes [Review]
- (2013) Shoichiro Tanaka et al. ENDOCRINE JOURNAL
- Seroconversion to Multiple Islet Autoantibodies and Risk of Progression to Diabetes in Children
- (2013) Anette G. Ziegler et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Infection of human islets of langerhans with two strains of coxsackie B virus serotype 1: Assessment of virus replication, degree of cell death and induction of genes involved in the innate immunity pathway
- (2013) Mahesh Anagandula et al. JOURNAL OF MEDICAL VIROLOGY
- Type 1 diabetes
- (2013) Mark A Atkinson et al. LANCET
- Evidence of association between type 1 diabetes and exposure to enterovirus in Cuban children and adolescents
- (2013) Luis Sarmiento et al. MEDICC Review
- Differential innate immune response programs in neuronal subtypes determine susceptibility to infection in the brain by positive-stranded RNA viruses
- (2013) Hyelim Cho et al. NATURE MEDICINE
- Cellular Self-Defense: How Cell-Autonomous Immunity Protects Against Pathogens
- (2013) F. Randow et al. SCIENCE
- Innate antiviral signalling in the central nervous system
- (2013) Michael Carty et al. TRENDS IN IMMUNOLOGY
- The Hygiene Hypothesis: An Explanation for the Increased Frequency of Insulin-Dependent Diabetes
- (2013) J.-F. Bach et al. Cold Spring Harbor Perspectives in Medicine
- GLIS3, a Susceptibility Gene for Type 1 and Type 2 Diabetes, Modulates Pancreatic Beta Cell Apoptosis via Regulation of a Splice Variant of the BH3-Only Protein Bim
- (2013) Tatiane C. Nogueira et al. PLoS Genetics
- The ‘Hygiene hypothesis’ and the sharp gradient in the incidence of autoimmune and allergic diseases between Russian Karelia and Finland
- (2012) Anita Kondrashova et al. APMIS
- Prevention or acceleration of type 1 diabetes by viruses
- (2012) Liana Ghazarian et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Identification of Novel Type 1 Diabetes Candidate Genes by Integrating Genome-Wide Association Data, Protein-Protein Interactions, and Human Pancreatic Islet Gene Expression
- (2012) R. Bergholdt et al. DIABETES
- Expression of the enteroviral capsid protein VP1 in the islet cells of patients with type 1 diabetes is associated with induction of protein kinase R and downregulation of Mcl-1
- (2012) S. J. Richardson et al. DIABETOLOGIA
- Mouse liver-specific CD8+ T-cells encounter their cognate antigen and acquire capacity to destroy target hepatocytes
- (2012) Sylvie Chabot et al. JOURNAL OF AUTOIMMUNITY
- Demonstration of islet-autoreactive CD8 T cells in insulitic lesions from recent onset and long-term type 1 diabetes patients
- (2012) Ken T. Coppieters et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Intrinsic antiviral immunity
- (2012) Nan Yan et al. NATURE IMMUNOLOGY
- Crosstalk between neutrophils, B-1a cells and plasmacytoid dendritic cells initiates autoimmune diabetes
- (2012) Julien Diana et al. NATURE MEDICINE
- USP18 is a key regulator of the interferon-driven gene network modulating pancreatic beta cell inflammation and apoptosis
- (2012) I Santin et al. Cell Death & Disease
- The Human Pancreatic Islet Transcriptome: Expression of Candidate Genes for Type 1 Diabetes and the Impact of Pro-Inflammatory Cytokines
- (2012) Décio L. Eizirik et al. PLoS Genetics
- An Interferon-Induced Helicase (IFIH1) Gene Polymorphism Associates With Different Rates of Progression From Autoimmunity to Type 1 Diabetes
- (2011) C. Winkler et al. DIABETES
- PTPN2, a Candidate Gene for Type 1 Diabetes, Modulates Pancreatic -Cell Apoptosis via Regulation of the BH3-Only Protein Bim
- (2011) I. Santin et al. DIABETES
- Type 1 Diabetes and Interferon Therapy: A nationwide survey in Japan
- (2011) K. Nakamura et al. DIABETES CARE
- Fulminant type 1 diabetes-an important subtype in East Asia
- (2011) Akihisa Imagawa et al. DIABETES-METABOLISM RESEARCH AND REVIEWS
- Immunohistochemical analysis of the relationship between islet cell proliferation and the production of the enteroviral capsid protein, VP1, in the islets of patients with recent-onset type 1 diabetes
- (2011) A. Willcox et al. DIABETOLOGIA
- A polymorphism in PTPN2 gene is associated with an earlier onset of type 1 diabetes
- (2011) Laura Espino-Paisan et al. IMMUNOGENETICS
- Bcl-2 proteins in diabetes: mitochondrial pathways of β-cell death and dysfunction
- (2011) Esteban N. Gurzov et al. TRENDS IN CELL BIOLOGY
- Meta-Analysis of Genome-Wide Association Studies in Celiac Disease and Rheumatoid Arthritis Identifies Fourteen Non-HLA Shared Loci
- (2011) Alexandra Zhernakova et al. PLoS Genetics
- Genetics of Type 1 Diabetes: What's Next?
- (2010) F. Pociot et al. DIABETES
- Specific gene expression signature associated with development of autoimmune type-I diabetes using whole-blood microarray analysis
- (2010) F Reynier et al. GENES AND IMMUNITY
- An autoimmune-associated variant in PTPN2 reveals an impairment of IL-2R signaling in CD4+ T cells
- (2010) S A Long et al. GENES AND IMMUNITY
- Etiology of Type 1 Diabetes
- (2010) John A. Todd IMMUNITY
- Meta-analysis of TYK2 gene polymorphisms association with susceptibility to autoimmune and inflammatory diseases
- (2010) Jin-Hui Tao et al. MOLECULAR BIOLOGY REPORTS
- A trans-acting locus regulates an anti-viral expression network and type 1 diabetes risk
- (2010) Matthias Heinig et al. NATURE
- Conversion of adult pancreatic α-cells to β-cells after extreme β-cell loss
- (2010) Fabrizio Thorel et al. NATURE
- Pathogenesis of type 1 diabetes mellitus: interplay between enterovirus and host
- (2010) Didier Hober et al. Nature Reviews Endocrinology
- Reduced Expression of IFIH1 Is Protective for Type 1 Diabetes
- (2010) Kate Downes et al. PLoS One
- Detection of Enterovirus RNA in Peripheral Blood Mononuclear Cells of Type 1 Diabetic Patients Beyond the Stage of Acute Infection
- (2010) Barbara M. Schulte et al. VIRAL IMMUNOLOGY
- PTPN2, a Candidate Gene for Type 1 Diabetes, Modulates Interferon- -Induced Pancreatic -Cell Apoptosis
- (2009) F. Moore et al. DIABETES
- The long lifespan and low turnover of human islet beta cells estimated by mathematical modelling of lipofuscin accumulation
- (2009) M. Cnop et al. DIABETOLOGIA
- The prevalence of enteroviral capsid protein vp1 immunostaining in pancreatic islets in human type 1 diabetes
- (2009) S. J. Richardson et al. DIABETOLOGIA
- MDA5 and PTPN2, two candidate genes for type 1 diabetes, modify pancreatic β-cell responses to the viral by-product double-stranded RNA
- (2009) Maikel L. Colli et al. HUMAN MOLECULAR GENETICS
- Antiviral effect of nicotinamide on enterovirus-infected human islets in vitro: Effect on virus replication and chemokine secretion
- (2009) Annika Moëll et al. JOURNAL OF MEDICAL VIROLOGY
- Incidence trends for childhood type 1 diabetes in Europe during 1989–2003 and predicted new cases 2005–20: a multicentre prospective registration study
- (2009) Christopher C Patterson et al. LANCET
- The imprinted DLK1-MEG3 gene region on chromosome 14q32.2 alters susceptibility to type 1 diabetes
- (2009) Chris Wallace et al. NATURE GENETICS
- The role of inflammation in insulitis and β-cell loss in type 1 diabetes
- (2009) Décio L. Eizirik et al. Nature Reviews Endocrinology
- Genetics of Type 1A Diabetes
- (2009) Patrick Concannon et al. NEW ENGLAND JOURNAL OF MEDICINE
- Rare Variants of IFIH1, a Gene Implicated in Antiviral Responses, Protect Against Type 1 Diabetes
- (2009) S. Nejentsev et al. SCIENCE
- MDA5/RIG-I and virus recognition
- (2008) Osamu Takeuchi et al. CURRENT OPINION IN IMMUNOLOGY
- Analysis of pancreas tissue in a child positive for islet cell antibodies
- (2008) M. Oikarinen et al. DIABETOLOGIA
- Review series on helminths, immune modulation and the hygiene hypothesis: How might infection modulate the onset of type 1 diabetes?
- (2008) Anne Cooke IMMUNOLOGY
- Selective inhibitors of picornavirus replication
- (2008) Armando M. De Palma et al. MEDICINAL RESEARCH REVIEWS
- Shared and Distinct Genetic Variants in Type 1 Diabetes and Celiac Disease
- (2008) Deborah J. Smyth et al. NEW ENGLAND JOURNAL OF MEDICINE
- Concordance for Islet Autoimmunity among Monozygotic Twins
- (2008) Maria J. Redondo et al. NEW ENGLAND JOURNAL OF MEDICINE
- Interferon- initiates type 1 diabetes in nonobese diabetic mice
- (2008) Q. Li et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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