标题
International AIDS Society global scientific strategy: towards an HIV cure 2016
作者
关键词
-
出版物
NATURE MEDICINE
Volume 22, Issue 8, Pages 839-850
出版商
Springer Nature
发表日期
2016-07-12
DOI
10.1038/nm.4108
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Treatment intensification followed by interleukin-7 reactivates HIV without reducing total HIV DNA
- (2016) Christine Katlama et al. AIDS
- Macrophages sustain HIV replication in vivo independently of T cells
- (2016) Jenna B. Honeycutt et al. JOURNAL OF CLINICAL INVESTIGATION
- Persistent HIV-1 replication maintains the tissue reservoir during therapy
- (2016) Ramon Lorenzo-Redondo et al. NATURE
- Clonally expanded CD4+T cells can produce infectious HIV-1 in vivo
- (2016) Francesco R. Simonetti et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Broadly targeted CD8+ T cell responses restricted by major histocompatibility complex E
- (2016) S. G. Hansen et al. SCIENCE
- HIV-1 virological remission lasting more than 12 years after interruption of early antiretroviral therapy in a perinatally infected teenager enrolled in the French ANRS EPF-CO10 paediatric cohort: a case report
- (2016) Pierre Frange et al. Lancet HIV
- Effect of ipilimumab on the HIV reservoir in an HIV-infected individual with metastatic melanoma
- (2015) Fiona Wightman et al. AIDS
- A low HIV-DNA level in peripheral blood mononuclear cells at antiretroviral treatment interruption predicts a higher probability of maintaining viral control
- (2015) Lambert Assoumou et al. AIDS
- Dendritic cell type-specific HIV-1 activation in effector T cells
- (2015) Renée M. van der Sluis et al. AIDS
- Stakeholder Engagement in HIV Cure Research: Lessons Learned from Other HIV Interventions and the Way Forward
- (2015) Ying-Ru Lo et al. AIDS PATIENT CARE AND STDS
- The Ethics of HIV “Cure” Research: What Can We Learn from Consent Forms?
- (2015) Gail E. Henderson AIDS RESEARCH AND HUMAN RETROVIRUSES
- Exploring the Social Meaning of Curing HIV: A Qualitative Study of People Who Inject Drugs in Guangzhou, China
- (2015) Carissa E. Chu et al. AIDS RESEARCH AND HUMAN RETROVIRUSES
- Exploring the Potential of Monoclonal Antibody Therapeutics for HIV-1 Eradication
- (2015) Zelda Euler et al. AIDS RESEARCH AND HUMAN RETROVIRUSES
- Elevated Plasma Viral Loads in Romidepsin-Treated Simian Immunodeficiency Virus-Infected Rhesus Macaques on Suppressive Combination Antiretroviral Therapy
- (2015) Gregory Q. Del Prete et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Cell-Associated HIV-1 DNA and RNA Decay Dynamics During Early Combination Antiretroviral Therapy in HIV-1-Infected Infants
- (2015) Priyanka Uprety et al. CLINICAL INFECTIOUS DISEASES
- Dual-Affinity Re-Targeting proteins direct T cell–mediated cytolysis of latently HIV-infected cells
- (2015) Julia A.M. Sung et al. JOURNAL OF CLINICAL INVESTIGATION
- Interleukin-21 combined with ART reduces inflammation and viral reservoir in SIV-infected macaques
- (2015) Luca Micci et al. JOURNAL OF CLINICAL INVESTIGATION
- Ex vivo analysis identifies effective HIV-1 latency–reversing drug combinations
- (2015) Gregory M. Laird et al. JOURNAL OF CLINICAL INVESTIGATION
- A Murine Viral Outgrowth Assay to Detect Residual HIV Type 1 in Patients With Undetectable Viral Loads
- (2015) Kelly A. Metcalf Pate et al. JOURNAL OF INFECTIOUS DISEASES
- Precise Quantitation of the Latent HIV-1 Reservoir: Implications for Eradication Strategies
- (2015) Amanda M. Crooks et al. JOURNAL OF INFECTIOUS DISEASES
- HIV-1 Virion Production from Single Inducible Proviruses following T-Cell ActivationEx Vivo
- (2015) John K. Bui et al. JOURNAL OF VIROLOGY
- Viraemia suppressed in HIV-1-infected humans by broadly neutralizing antibody 3BNC117
- (2015) Marina Caskey et al. NATURE
- AAV-expressed eCD4-Ig provides durable protection from multiple SHIV challenges
- (2015) Matthew R. Gardner et al. NATURE
- Broad CTL response is required to clear latent HIV-1 due to dominance of escape mutations
- (2015) Kai Deng et al. NATURE
- B cell follicle sanctuary permits persistent productive simian immunodeficiency virus infection in elite controllers
- (2015) Yoshinori Fukazawa et al. NATURE MEDICINE
- Whole-body immunoPET reveals active SIV dynamics in viremic and antiretroviral therapy–treated macaques
- (2015) Philip J Santangelo et al. NATURE METHODS
- Genetic engineering of hematopoietic stem cells to generate invariant natural killer T cells
- (2015) Drake J. Smith et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Virologic effects of broadly neutralizing antibody VRC01 administration during chronic HIV-1 infection
- (2015) Rebecca M. Lynch et al. Science Translational Medicine
- The Tat Inhibitor Didehydro-Cortistatin A Prevents HIV-1 Reactivation from Latency
- (2015) Guillaume Mousseau et al. mBio
- Immunological biomarkers predict HIV-1 viral rebound after treatment interruption
- (2015) Jacob Hurst et al. Nature Communications
- Activation and lysis of human CD4 cells latently infected with HIV-1
- (2015) Amarendra Pegu et al. Nature Communications
- The Depsipeptide Romidepsin Reverses HIV-1 Latency In Vivo
- (2015) Ole S. Søgaard et al. PLoS Pathogens
- Short-term administration of disulfiram for reversal of latent HIV infection: a phase 2 dose-escalation study
- (2015) Julian H Elliott et al. Lancet HIV
- A Novel Assay to Measure the Magnitude of the Inducible Viral Reservoir in HIV-infected Individuals
- (2015) Francesco Andrea Procopio et al. EBioMedicine
- Social and ethical implications of HIV cure research
- (2014) Joseph D. Tucker et al. AIDS
- Reduced markers of HIV persistence and restricted HIV-specific immune responses after early antiretroviral therapy in children
- (2014) Jintanat Ananworanich et al. AIDS
- Reactivation of HIV latency by a newly modified Ingenol derivative via protein kinase Cδ–NF-κB signaling
- (2014) Guochun Jiang et al. AIDS
- Lifespan of effector memory CD4+ T cells determined by replication-incompetent integrated HIV-1 provirus
- (2014) Hiromi Imamichi et al. AIDS
- Reduction of HIV Persistence Following Transplantation in HIV-Infected Kidney Transplant Recipients
- (2014) P. G. Stock et al. AMERICAN JOURNAL OF TRANSPLANTATION
- Antiretroviral-Free HIV-1 Remission and Viral Rebound After Allogeneic Stem Cell Transplantation
- (2014) Timothy J. Henrich et al. ANNALS OF INTERNAL MEDICINE
- Broadly Neutralizing Antibodies and Viral Inducers Decrease Rebound from HIV-1 Latent Reservoirs in Humanized Mice
- (2014) Ariel Halper-Stromberg et al. CELL
- Advancing community stakeholder engagement in biomedical HIV prevention trials: principles, practices and evidence
- (2014) Peter A Newman et al. Expert Review of Vaccines
- Tissue Myeloid Cells in SIV-Infected Primates Acquire Viral DNA through Phagocytosis of Infected T Cells
- (2014) Nina Calantone et al. IMMUNITY
- Words Matter
- (2014) Joseph D. Tucker et al. JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES
- An HIV Cure
- (2014) Anthony S. Fauci et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- HIV-1 transcriptional regulation in the central nervous system and implications for HIV cure research
- (2014) Melissa J. Churchill et al. JOURNAL OF NEUROVIROLOGY
- HIV DNA Subspecies Persist in both Activated and Resting Memory CD4+ T Cells during Antiretroviral Therapy
- (2014) J. M. Murray et al. JOURNAL OF VIROLOGY
- Rapid seeding of the viral reservoir prior to SIV viraemia in rhesus monkeys
- (2014) James B. Whitney et al. NATURE
- Vectored immunoprophylaxis protects humanized mice from mucosal HIV transmission
- (2014) Alejandro B Balazs et al. NATURE MEDICINE
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- (2014) Maria J Buzon et al. NATURE MEDICINE
- Gene Editing of CCR5 in Autologous CD4 T Cells of Persons Infected with HIV
- (2014) Pablo Tebas et al. NEW ENGLAND JOURNAL OF MEDICINE
- Chimeric Antigen Receptor T Cells for Sustained Remissions in Leukemia
- (2014) Shannon L. Maude et al. NEW ENGLAND JOURNAL OF MEDICINE
- Absence of HIV-1 after Treatment Cessation in an Infant
- (2014) NEW ENGLAND JOURNAL OF MEDICINE
- HIV Cure Strategies: How Good Must They Be to Improve on Current Antiretroviral Therapy?
- (2014) Paul E. Sax et al. PLoS One
- Broadly neutralizing antibodies suppress HIV in the persistent viral reservoir
- (2014) T.-W. Chun et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Persistent HIV-1 replication is associated with lower antiretroviral drug concentrations in lymphatic tissues
- (2014) Courtney V. Fletcher et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Quantification of HIV-1 latency reversal in resting CD4+ T cells from patients on suppressive antiretroviral therapy
- (2014) A. R. Cillo et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- RNA-directed gene editing specifically eradicates latent and prevents new HIV-1 infection
- (2014) W. Hu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Proliferation of cells with HIV integrated into cancer genes contributes to persistent infection
- (2014) T. A. Wagner et al. SCIENCE
- Specific HIV integration sites are linked to clonal expansion and persistence of infected cells
- (2014) F. Maldarelli et al. SCIENCE
- Immunologic strategies for HIV-1 remission and eradication
- (2014) D. H. Barouch et al. SCIENCE
- Activation of HIV Transcription with Short-Course Vorinostat in HIV-Infected Patients on Suppressive Antiretroviral Therapy
- (2014) Julian H. Elliott et al. PLoS Pathogens
- Targeted Cytotoxic Therapy Kills Persisting HIV Infected Cells During ART
- (2014) Paul W. Denton et al. PLoS Pathogens
- Histone Deacetylase Inhibitors Impair the Elimination of HIV-Infected Cells by Cytotoxic T-Lymphocytes
- (2014) Richard Brad Jones et al. PLoS Pathogens
- Lack of Detectable HIV-1 Molecular Evolution during Suppressive Antiretroviral Therapy
- (2014) Mary F. Kearney et al. PLoS Pathogens
- Influence of Age at Virologic Control on Peripheral Blood Human Immunodeficiency Virus Reservoir Size and Serostatus in Perinatally Infected Adolescents
- (2014) Deborah Persaud et al. JAMA Pediatrics
- Immunity to HIV in Early Life
- (2014) Maximilian Muenchhoff et al. Frontiers in Immunology
- Panobinostat, a histone deacetylase inhibitor, for latent-virus reactivation in HIV-infected patients on suppressive antiretroviral therapy: a phase 1/2, single group, clinical trial
- (2014) Thomas A Rasmussen et al. Lancet HIV
- Entinostat is a histone deacetylase inhibitor selective for class 1 histone deacetylases and activates HIV production from latently infected primary T cells
- (2013) Fiona Wightman et al. AIDS
- Positive selection of mC46-expressing CD4+ T cells and maintenance of virus specific immunity in a primate AIDS model
- (2013) P. M. Younan et al. BLOOD
- Interleukin-7 promotes HIV persistence during antiretroviral therapy
- (2013) C. Vandergeeten et al. BLOOD
- Replication-Competent Noninduced Proviruses in the Latent Reservoir Increase Barrier to HIV-1 Cure
- (2013) Ya-Chi Ho et al. CELL
- BET bromodomain-targeting compounds reactivate HIV from latency via a Tat-independent mechanism
- (2013) Daniela Boehm et al. CELL CYCLE
- Increase in 2–Long Terminal Repeat Circles and Decrease in D-dimer After Raltegravir Intensification in Patients With Treated HIV Infection: A Randomized, Placebo-Controlled Trial
- (2013) Hiroyu Hatano et al. JOURNAL OF INFECTIOUS DISEASES
- HIV Antibody Characterization as a Method to Quantify Reservoir Size During Curative Interventions
- (2013) P. D. Burbelo et al. JOURNAL OF INFECTIOUS DISEASES
- The Distribution of HIV DNA and RNA in Cell Subsets Differs in Gut and Blood of HIV-Positive Patients on ART: Implications for Viral Persistence
- (2013) Steven A. Yukl et al. JOURNAL OF INFECTIOUS DISEASES
- Therapeutic Vaccination Expands and Improves the Function of the HIV-Specific Memory T-Cell Repertoire
- (2013) Joseph P. Casazza et al. JOURNAL OF INFECTIOUS DISEASES
- Immune clearance of highly pathogenic SIV infection
- (2013) Scott G. Hansen et al. NATURE
- Past, present and future: 30 years of HIV research
- (2013) Françoise Barré-Sinoussi et al. NATURE REVIEWS MICROBIOLOGY
- Absence of Detectable HIV-1 Viremia after Treatment Cessation in an Infant
- (2013) Deborah Persaud et al. NEW ENGLAND JOURNAL OF MEDICINE
- Chimeric Antigen Receptor–Modified T Cells for Acute Lymphoid Leukemia
- (2013) Stephan A. Grupp et al. NEW ENGLAND JOURNAL OF MEDICINE
- The HIV-1 reservoir in eight patients on long-term suppressive antiretroviral therapy is stable with few genetic changes over time
- (2013) L. Josefsson et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Cytomegalovirus Vectors Violate CD8+ T Cell Epitope Recognition Paradigms
- (2013) S. G. Hansen et al. SCIENCE
- An In-Depth Comparison of Latent HIV-1 Reactivation in Multiple Cell Model Systems and Resting CD4+ T Cells from Aviremic Patients
- (2013) Celsa A. Spina et al. PLoS Pathogens
- Comparative Analysis of Measures of Viral Reservoirs in HIV-1 Eradication Studies
- (2013) Susanne Eriksson et al. PLoS Pathogens
- Challenges in Detecting HIV Persistence during Potentially Curative Interventions: A Study of the Berlin Patient
- (2013) Steven A. Yukl et al. PLoS Pathogens
- Post-Treatment HIV-1 Controllers with a Long-Term Virological Remission after the Interruption of Early Initiated Antiretroviral Therapy ANRS VISCONTI Study
- (2013) Asier Sáez-Cirión et al. PLoS Pathogens
- Myeloid Dendritic Cells Induce HIV-1 Latency in Non-proliferating CD4+ T Cells
- (2013) Vanessa A. Evans et al. PLoS Pathogens
- Rapid Quantification of the Latent Reservoir for HIV-1 Using a Viral Outgrowth Assay
- (2013) Gregory M. Laird et al. PLoS Pathogens
- Stimulation of HIV-1-Specific Cytolytic T Lymphocytes Facilitates Elimination of Latent Viral Reservoir after Virus Reactivation
- (2012) Liang Shan et al. IMMUNITY
- Cell-Based Measures of Viral Persistence Are Associated With Immune Activation and Programmed Cell Death Protein 1 (PD-1)–Expressing CD4+ T cells
- (2012) Hiroyu Hatano et al. JOURNAL OF INFECTIOUS DISEASES
- Administration of vorinostat disrupts HIV-1 latency in patients on antiretroviral therapy
- (2012) N. M. Archin et al. NATURE
- Immediate antiviral therapy appears to restrict resting CD4+ cell HIV-1 infection without accelerating the decay of latent infection
- (2012) N. M. Archin et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- In Vivo Suppression of HIV by Antigen Specific T Cells Derived from Engineered Hematopoietic Stem Cells
- (2012) Scott G. Kitchen et al. PLoS Pathogens
- HIV Latency in the Humanized BLT Mouse
- (2011) M. D. Marsden et al. JOURNAL OF VIROLOGY
- Generation of HIV Latency in Humanized BLT Mice
- (2011) P. W. Denton et al. JOURNAL OF VIROLOGY
- Profound early control of highly pathogenic SIV by an effector memory T-cell vaccine
- (2011) Scott G. Hansen et al. NATURE
- Efficient and stable MGMT-mediated selection of long-term repopulating stem cells in nonhuman primates
- (2010) Brian C. Beard et al. JOURNAL OF CLINICAL INVESTIGATION
- Establishment of HIV Latency in Primary CD4+ Cells Is due to Epigenetic Transcriptional Silencing and P-TEFb Restriction
- (2010) M. Tyagi et al. JOURNAL OF VIROLOGY
- HIV-1 replication and immune dynamics are affected by raltegravir intensification of HAART-suppressed subjects
- (2010) Maria J Buzón et al. NATURE MEDICINE
- The Major Genetic Determinants of HIV-1 Control Affect HLA Class I Peptide Presentation
- (2010) SCIENCE
- RNA-Based Gene Therapy for HIV with Lentiviral Vector-Modified CD34+ Cells in Patients Undergoing Transplantation for AIDS-Related Lymphoma
- (2010) D. L. DiGiusto et al. Science Translational Medicine
- Chemokine receptor 5 knockout strategies
- (2010) Paula Cannon et al. Current Opinion in HIV and AIDS
- HIV reservoir size and persistence are driven by T cell survival and homeostatic proliferation
- (2009) Nicolas Chomont et al. NATURE MEDICINE
- Long-Term Control of HIV byCCR5Delta32/Delta32 Stem-Cell Transplantation
- (2009) Gero Hütter et al. NEW ENGLAND JOURNAL OF MEDICINE
- Orientation-Dependent Regulation of Integrated HIV-1 Expression by Host Gene Transcriptional Readthrough
- (2008) Yefei Han et al. Cell Host & Microbe
- Dangerous medicines: Unproven AIDS cures and counterfeit antiretroviral drugs
- (2008) Joseph J Amon Globalization and Health
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