Histone Deacetylase Inhibitors Impair the Elimination of HIV-Infected Cells by Cytotoxic T-Lymphocytes

Study of Marine Natural Products Including Resorcyclic Acid Lactones from Humicola fuscoatra That Reactivate Latent HIV-1 Expression in an in Vitro Model of Central Memory CD4+ T Cells

(2014) Eric J. Mejia et al.   JOURNAL OF NATURAL PRODUCTS

High Avidity CD8+ T Cells Efficiently Eliminate Motile HIV-Infected Targets and Execute a Locally Focused Program of Anti-Viral Function

(2014) Maria Hottelet Foley et al.   PLoS One

Histone Deacetylase Inhibitor Romidepsin Induces HIV Expression in CD4 T Cells from Patients on Suppressive Antiretroviral Therapy at Concentrations Achieved by Clinical Dosing

(2014) Datsen George Wei et al.   PLoS Pathogens

The end of AIDS: HIV infection as a chronic disease

(2013) Steven G Deeks et al.   LANCET

HDAC Inhibition Suppresses Primary Immune Responses, Enhances Secondary Immune Responses, and Abrogates Autoimmunity During Tumor Immunotherapy

(2013) Byram W Bridle et al.   MOLECULAR THERAPY

Comparison of HDAC inhibitors in clinical development

(2013) Thomas Aagaard Rasmussen et al.   Human Vaccines & Immunotherapeutics

The histone deacetylase inhibitor, romidepsin, suppresses cellular immune functions of cutaneous T-cell lymphoma patients

(2012) Michael J. Kelly-Sell et al.   AMERICAN JOURNAL OF HEMATOLOGY

LBH589 Enhances T Cell Activation In Vivo and Accelerates Graft-versus-Host Disease in Mice

(2012) Dapeng Wang et al.   BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION

Histone/protein deacetylases and T-cell immune responses

(2012) T. Akimova et al.   BLOOD

Vorinostat, a histone deacetylase inhibitor, suppresses dendritic cell function and ameliorates experimental autoimmune encephalomyelitis

(2012) Zhenzhen Ge et al.   EXPERIMENTAL NEUROLOGY

Stimulation of HIV-1-Specific Cytolytic T Lymphocytes Facilitates Elimination of Latent Viral Reservoir after Virus Reactivation

(2012) Liang Shan et al.   IMMUNITY

Histone deacetylase inhibitor suberoylanilide hydroxamic acid exhibits anti-inflammatory activities through induction of mitochondrial damage and apoptosis in activated lymphocytes

(2012) Zi-jian Shi et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

HERV-K–specific T cells eliminate diverse HIV-1/2 and SIV primary isolates

(2012) R. Brad Jones et al.   JOURNAL OF CLINICAL INVESTIGATION

Administration of vorinostat disrupts HIV-1 latency in patients on antiretroviral therapy

(2012) N. M. Archin et al.   NATURE

The effect of food on the bioavailability of panobinostat, an orally active pan-histone deacetylase inhibitor, in patients with advanced cancer

(2011) Geoffrey I. Shapiro et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Histone/protein deacetylases control Foxp3 expression and the heat shock response of T-regulatory cells

(2011) Ulf H Beier et al.   CURRENT OPINION IN IMMUNOLOGY

IL-15:IL-15 receptor alpha superagonist complex: High-level co-expression in recombinant mammalian cells, purification and characterization

(2011) Kai-ping Han et al.   CYTOKINE

HDAC inhibitors in HIV

(2011) Fiona Wightman et al.   IMMUNOLOGY AND CELL BIOLOGY

HIV Infection, Inflammation, Immunosenescence, and Aging

(2010) Steven G. Deeks   Annual Review of Medicine

HIV-1 replication and immune dynamics are affected by raltegravir intensification of HAART-suppressed subjects

(2010) Maria J Buzón et al.   NATURE MEDICINE

Synchronous infection of SIV and HIV in vitro for virology, immunology and vaccine-related studies

(2010) Jonah B Sacha et al.   Nature Protocols

Expression of Latent HIV Induced by the Potent HDAC Inhibitor Suberoylanilide Hydroxamic Acid

(2009) Nancie M. Archin et al.   AIDS RESEARCH AND HUMAN RETROVIRUSES

Valproic acid (VPA), a histone deacetylase (HDAC) inhibitor, diminishes lymphoproliferation in the Fas -deficient MRL/lpr−/− murine model of autoimmune lymphoproliferative syndrome (ALPS)

(2009) Kennichi C. Dowdell et al.   EXPERIMENTAL HEMATOLOGY

Novel Human Interleukin-15 Agonists

(2009) X. Zhu et al.   JOURNAL OF IMMUNOLOGY

Human Immunodeficiency Virus Type 1 Escapes from Interleukin-2-Producing CD4+ T-Cell Responses without High-Frequency Fixation of Mutations

(2009) R. B. Jones et al.   JOURNAL OF VIROLOGY

HIV reservoir size and persistence are driven by T cell survival and homeostatic proliferation

(2009) Nicolas Chomont et al.   NATURE MEDICINE

The role of IFN-γ Elispot assay in HIV vaccine research

(2009) Hendrik Streeck et al.   Nature Protocols

Determination of the class and isoform selectivity of small-molecule histone deacetylase inhibitors

(2008) Nagma Khan et al.   BIOCHEMICAL JOURNAL

Butyrate inhibits functional differentiation of human monocyte-derived dendritic cells

(2008) Biao Wang et al.   CELLULAR IMMUNOLOGY

Blocking TH 17-polarizing cytokines by histone deacetylase inhibitors in vitro and in vivo

(2008) Daniela Bosisio et al.   JOURNAL OF LEUKOCYTE BIOLOGY