Tcf1 and Lef1 transcription factors establish CD8+ T cell identity through intrinsic HDAC activity

From inception to output, Tcf1 and Lef1 safeguard development of T cells and innate immune cells

(2014) Farrah C. Steinke et al.   IMMUNOLOGIC RESEARCH

A ThPOK-LRF transcriptional node maintains the integrity and effector potential of post-thymic CD4+ T cells

(2014) Melanie S Vacchio et al.   NATURE IMMUNOLOGY

TCF-1 and LEF-1 act upstream of Th-POK to promote the CD4+ T cell fate and interact with Runx3 to silence Cd4 in CD8+ T cells

(2014) Farrah C Steinke et al.   NATURE IMMUNOLOGY

CD4+ T cell lineage integrity is controlled by the histone deacetylases HDAC1 and HDAC2

(2014) Nicole Boucheron et al.   NATURE IMMUNOLOGY

SWISS-MODEL: modelling protein tertiary and quaternary structure using evolutionary information

(2014) Marco Biasini et al.   NUCLEIC ACIDS RESEARCH

UniProt: a hub for protein information

(2014)   NUCLEIC ACIDS RESEARCH

Dynamics and stability: epigenetic conversions in position effect variegation

(2013) Krassimir Yankulov   Biochemistry and Cell Biology

EBSeq: an empirical Bayes hierarchical model for inference in RNA-seq experiments

(2013) Ning Leng et al.   BIOINFORMATICS

Histone deacetylase 1 and 2 are essential for normal T-cell development and genomic stability in mice

(2013) O. M. Dovey et al.   BLOOD

Canonical Wnt Signaling Negatively Modulates Regulatory T Cell Function

(2013) Jorg van Loosdregt et al.   IMMUNITY

The transcriptional landscape of αβ T cell differentiation

(2013) Michael Mingueneau et al.   NATURE IMMUNOLOGY

Targeting Tetramer-Forming GABPβ Isoforms Impairs Self-Renewal of Hematopoietic and Leukemic Stem Cells

(2012) Shuyang Yu et al.   Cell Stem Cell

The TCF-1 and LEF-1 Transcription Factors Have Cooperative and Opposing Roles in T Cell Development and Malignancy

(2012) Shuyang Yu et al.   IMMUNITY

The Nuclear Effector of Wnt-Signaling, Tcf1, Functions as a T-Cell–Specific Tumor Suppressor for Development of Lymphomas

(2012) Machteld M. Tiemessen et al.   PLOS BIOLOGY

RSEM: accurate transcript quantification from RNA-Seq data with or without a reference genome

(2011) Bo Li et al.   BMC BIOINFORMATICS

Histone Deacetylase 7 Regulates Cell Survival and TCR Signaling in CD4/CD8 Double-Positive Thymocytes

(2011) H. G. Kasler et al.   JOURNAL OF IMMUNOLOGY

A critical role for TCF-1 in T-lineage specification and differentiation

(2011) Brittany Nicole Weber et al.   NATURE

T-cell factor 1 is a gatekeeper for T-cell specification in response to Notch signaling

(2011) K. Germar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Direct-coupling analysis of residue coevolution captures native contacts across many protein families

(2011) F. Morcos et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

HDACi - going through the mechanisms

(2010) Malgorzata Wanczyk   Frontiers in Bioscience-Landmark

Maintaining Cell Identity through Global Control of Genomic Organization

(2010) Gioacchino Natoli   IMMUNITY

Reprogramming of T Cells to Natural Killer-Like Cells upon Bcl11b Deletion

(2010) P. Li et al.   SCIENCE

A clustering approach for identification of enriched domains from histone modification ChIP-Seq data

(2009) Chongzhi Zang et al.   BIOINFORMATICS

Structural Studies of Human Histone Deacetylase 8 and Its Site-Specific Variants Complexed with Substrate and Inhibitors†,‡

(2008) Daniel P. Dowling et al.   BIOCHEMISTRY

Lymphoid enhancer factor interacts with GATA-3 and controls its function in T helper type 2 cells

(2008) Mohammad B. Hossain et al.   IMMUNOLOGY

The Rpd3/Hda1 family of lysine deacetylases: from bacteria and yeast to mice and men

(2008) Xiang-Jiao Yang et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Model-based Analysis of ChIP-Seq (MACS)

(2008) Yong Zhang et al.   GENOME BIOLOGY