Programs for the persistence, vigilance and control of human CD8+ lung-resident memory T cells

Hobit and Blimp1 instruct a universal transcriptional program of tissue residency in lymphocytes

(2016) L. K. Mackay et al.   SCIENCE

IL-7-Induced Glycerol Transport and TAG Synthesis Promotes Memory CD8+ T Cell Longevity

(2015) Guoliang Cui et al.   CELL

Quantifying Memory CD8 T Cells Reveals Regionalization of Immunosurveillance

(2015) Elizabeth M. Steinert et al.   CELL

Blimp-1 homolog Hobit identifies effector-type lymphocytes in humans

(2015) Felipe A. Vieira Braga et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

T-box Transcription Factors Combine with the Cytokines TGF-β and IL-15 to Control Tissue-Resident Memory T Cell Fate

(2015) Laura K. Mackay et al.   IMMUNITY

Airway-Resident Memory CD8 T Cells Provide Antigen-Specific Protection against Respiratory Virus Challenge through Rapid IFN-γ Production

(2015) Sean R. McMaster et al.   JOURNAL OF IMMUNOLOGY

Single-cell messenger RNA sequencing reveals rare intestinal cell types

(2015) Dominic Grün et al.   NATURE

Metabolic control of type 1 regulatory T cell differentiation by AHR and HIF1-α

(2015) Ivan D Mascanfroni et al.   NATURE MEDICINE

The emerging role of resident memory T cells in protective immunity and inflammatory disease

(2015) Chang Ook Park et al.   NATURE MEDICINE

Notch Receptor-Ligand Engagement Maintains Hematopoietic Stem Cell Quiescence and Niche Retention

(2015) Weihuan Wang et al.   STEM CELLS

Notch in T Cell Differentiation: All Things Considered

(2015) Derk Amsen et al.   TRENDS IN IMMUNOLOGY

Oral Infection Drives a Distinct Population of Intestinal Resident Memory CD8+ T Cells with Enhanced Protective Function

(2014) Brian S. Sheridan et al.   IMMUNITY

Editorial: Pulmonary resident memory CD8 T cells: here today, gone tomorrow

(2014) Kristin G. Anderson et al.   JOURNAL OF LEUKOCYTE BIOLOGY

A central role for Notch in effector CD8+ T cell differentiation

(2014) Ronald A Backer et al.   NATURE IMMUNOLOGY

Notch controls the survival of memory CD4+ T cells by regulating glucose uptake

(2014) Yoichi Maekawa et al.   NATURE MEDICINE

Skin-resident memory CD8+ T cells trigger a state of tissue-wide pathogen alert

(2014) S. Ariotti et al.   SCIENCE

Notch controls generation and function of human effector CD8+ T cells

(2013) L. M. Kuijk et al.   BLOOD

Lung Airway-Surveilling CXCR3hi Memory CD8+ T Cells Are Critical for Protection against Influenza A Virus

(2013) Bram Slütter et al.   IMMUNITY

Notch Simultaneously Orchestrates Multiple Helper T Cell Programs Independently of Cytokine Signals

(2013) Will Bailis et al.   IMMUNITY

BATF is required for normal expression of gut-homing receptors by T helper cells in response to retinoic acid

(2013) Chuanwu Wang et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Lung-resident memory CD8 T cells (TRM ) are indispensable for optimal cross-protection against pulmonary virus infection

(2013) Tao Wu et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Lung niches for the generation and maintenance of tissue-resident memory T cells

(2013) D L Turner et al.   Mucosal Immunology

BACH2 represses effector programs to stabilize Treg-mediated immune homeostasis

(2013) Rahul Roychoudhuri et al.   NATURE

Hypoxia-inducible factors enhance the effector responses of CD8+ T cells to persistent antigen

(2013) Andrew L Doedens et al.   NATURE IMMUNOLOGY

Transcriptional downregulation of S1pr1 is required for the establishment of resident memory CD8+ T cells

(2013) Cara N Skon et al.   NATURE IMMUNOLOGY

Sensing and alarm function of resident memory CD8+ T cells

(2013) Jason M Schenkel et al.   NATURE IMMUNOLOGY

The developmental pathway for CD103+CD8+ tissue-resident memory T cells of skin

(2013) Laura K Mackay et al.   NATURE IMMUNOLOGY

Cellular immune correlates of protection against symptomatic pandemic influenza

(2013) Saranya Sridhar et al.   NATURE MEDICINE

Conservation and divergence in the transcriptional programs of the human and mouse immune systems

(2013) T. Shay et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Notch Receptors and Smad3 Signaling Cooperate in the Induction of Interleukin-9-Producing T Cells

(2012) Wassim Elyaman et al.   IMMUNITY

Maintenance of Peripheral Naive T Cells Is Sustained by Thymus Output in Mice but Not Humans

(2012) Ineke den Braber et al.   IMMUNITY

Distribution and Compartmentalization of Human Circulating and Tissue-Resident Memory T Cell Subsets

(2012) Taheri Sathaliyawala et al.   IMMUNITY

Preexisting influenza-specific CD4+ T cells correlate with disease protection against influenza challenge in humans

(2012) Tom M Wilkinson et al.   NATURE MEDICINE

Camera: a competitive gene set test accounting for inter-gene correlation

(2012) Di Wu et al.   NUCLEIC ACIDS RESEARCH

Notch controls the magnitude of T helper cell responses by promoting cellular longevity

(2012) C. Helbig et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Exogenous Stimuli Maintain Intraepithelial Lymphocytes via Aryl Hydrocarbon Receptor Activation

(2011) Ying Li et al.   CELL

The Transcription Factor Myc Controls Metabolic Reprogramming upon T Lymphocyte Activation

(2011) Ruoning Wang et al.   IMMUNITY

CD8+ T cells with an intraepithelial phenotype upregulate cytotoxic function upon influenza infection in human lung

(2011) Berber Piet et al.   JOURNAL OF CLINICAL INVESTIGATION

Control of TH17 cells occurs in the small intestine

(2011) Enric Esplugues et al.   NATURE

Regional and mucosal memory T cells

(2011) Brian S Sheridan et al.   NATURE IMMUNOLOGY

Glucose Depletion in the Airway Surface Liquid Is Essential for Sterility of the Airways

(2011) Alejandro A. Pezzulo et al.   PLoS One

Sprouty Proteins Inhibit Receptor-mediated Activation of Phosphatidylinositol-specific Phospholipase C

(2010) Simge Akbulut et al.   MOLECULAR BIOLOGY OF THE CELL

Optimizing the noise versus bias trade-off for Illumina whole genome expression BeadChips

(2010) Wei Shi et al.   NUCLEIC ACIDS RESEARCH

edgeR: a Bioconductor package for differential expression analysis of digital gene expression data

(2009) M. D. Robinson et al.   BIOINFORMATICS

THE CHEMOKINE CXCL16 IS HIGHLY AND CONSTITUTIVELY EXPRESSED BY HUMAN BRONCHIAL EPITHELIAL CELLS

(2009) Caroline Day et al.   EXPERIMENTAL LUNG RESEARCH

Vaccination against Human Influenza A/H3N2 Virus Prevents the Induction of Heterosubtypic Immunity against Lethal Infection with Avian Influenza A/H5N1 Virus

(2009) Rogier Bodewes et al.   PLoS One

Direct regulation of TWIST by HIF-1α promotes metastasis

(2008) Muh-Hwa Yang et al.   NATURE CELL BIOLOGY