A central role for Notch in effector CD8+ T cell differentiation

Single cell behavior in T cell differentiation

(2014) Jan C. Rohr et al.   TRENDS IN IMMUNOLOGY

Notch controls generation and function of human effector CD8+ T cells

(2013) L. M. Kuijk et al.   BLOOD

Effector-like CD8+ T Cells in the Memory Population Mediate Potent Protective Immunity

(2013) Janelle A. Olson et al.   IMMUNITY

Notch Simultaneously Orchestrates Multiple Helper T Cell Programs Independently of Cytokine Signals

(2013) Will Bailis et al.   IMMUNITY

Hypoxia-inducible factors enhance the effector responses of CD8+ T cells to persistent antigen

(2013) Andrew L Doedens et al.   NATURE IMMUNOLOGY

Count-based differential expression analysis of RNA sequencing data using R and Bioconductor

(2013) Simon Anders et al.   Nature Protocols

Lung Dendritic Cells in Respiratory Viral Infection and Asthma: From Protection to Immunopathology

(2012) Bart N. Lambrecht et al.   Annual Review of Immunology

Transcription Factor Foxo1 Represses T-bet-Mediated Effector Functions and Promotes Memory CD8+ T Cell Differentiation

(2012) Rajesh R. Rao et al.   IMMUNITY

Cross-presenting CD103+ dendritic cells are protected from influenza virus infection

(2012) Julie Helft et al.   JOURNAL OF CLINICAL INVESTIGATION

PDK1 regulation of mTOR and hypoxia-inducible factor 1 integrate metabolism and migration of CD8+T cells

(2012) David K. Finlay et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Signal Integration by Akt Regulates CD8 T Cell Effector and Memory Differentiation

(2012) E. H. Kim et al.   JOURNAL OF IMMUNOLOGY

The Notch signalling system: recent insights into the complexity of a conserved pathway

(2012) K. G. Guruharsha et al.   NATURE REVIEWS GENETICS

Type-I IFN drives the differentiation of short-lived effector CD8+T cells in vivo

(2011) Melanie Wiesel et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Protein Kinase B Controls Transcriptional Programs that Direct Cytotoxic T Cell Fate but Is Dispensable for T Cell Metabolism

(2011) Andrew N. Macintyre et al.   IMMUNITY

An Interleukin-21- Interleukin-10-STAT3 Pathway Is Critical for Functional Maturation of Memory CD8+ T Cells

(2011) Weiguo Cui et al.   IMMUNITY

Pathogen-Induced Inflammatory Environment Controls Effector and Memory CD8 + T Cell Differentiation

(2011) Joshua J. Obar et al.   JOURNAL OF IMMUNOLOGY

Repression of the DNA-binding inhibitor Id3 by Blimp-1 limits the formation of memory CD8+ T cells

(2011) Yun Ji et al.   NATURE IMMUNOLOGY

The transcriptional regulators Id2 and Id3 control the formation of distinct memory CD8+ T cell subsets

(2011) Cliff Y Yang et al.   NATURE IMMUNOLOGY

The Critical Role of Notch Ligand Delta-like 1 in the Pathogenesis of Influenza A Virus (H1N1) Infection

(2011) Toshihiro Ito et al.   PLoS Pathogens

Interleukin-2 and Inflammation Induce Distinct Transcriptional Programs that Promote the Differentiation of Effector Cytolytic T Cells

(2010) Matthew E. Pipkin et al.   IMMUNITY

The mTOR Kinase Determines Effector versus Memory CD8 + T Cell Fate by Regulating the Expression of Transcription Factors T-bet and Eomesodermin

(2010) Rajesh R. Rao et al.   IMMUNITY

Differentiation and Persistence of Memory CD8+ T Cells Depend on T Cell Factor 1

(2010) Xinyuan Zhou et al.   IMMUNITY

Differential Localization of Effector and Memory CD8 T Cell Subsets in Lymphoid Organs during Acute Viral Infection

(2010) Y. W. Jung et al.   JOURNAL OF IMMUNOLOGY

Differential effects of STAT5 and PI3K/AKT signaling on effector and memory CD8 T-cell survival

(2010) T. W. Hand et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pathway analysis of dilated cardiomyopathy using global proteomic profiling and enrichment maps

(2010) Ruth Isserlin et al.   PROTEOMICS

Gene ontology analysis for RNA-seq: accounting for selection bias

(2010) Matthew D Young et al.   GENOME BIOLOGY

The Canonical Notch Signaling Pathway: Unfolding the Activation Mechanism

(2009) Raphael Kopan et al.   CELL

Transcriptional Repressor Blimp-1 Promotes CD8+ T Cell Terminal Differentiation and Represses the Acquisition of Central Memory T Cell Properties

(2009) Rachel L. Rutishauser et al.   IMMUNITY

Blimp-1 Transcription Factor Is Required for the Differentiation of Effector CD8+ T Cells and Memory Responses

(2009) Axel Kallies et al.   IMMUNITY

Notch Regulates Cytolytic Effector Function in CD8+ T Cells

(2009) O. H. Cho et al.   JOURNAL OF IMMUNOLOGY

Immunization with Live Attenuated Influenza Viruses That Express Altered NS1 Proteins Results in Potent and Protective Memory CD8+ T-Cell Responses

(2009) S. N. Mueller et al.   JOURNAL OF VIROLOGY

Enhancing CD8 T-cell memory by modulating fatty acid metabolism

(2009) Erika L. Pearce et al.   NATURE

mTOR regulates memory CD8 T-cell differentiation

(2009) Koichi Araki et al.   NATURE

Wnt signaling arrests effector T cell differentiation and generates CD8+ memory stem cells

(2009) Luca Gattinoni et al.   NATURE MEDICINE

CD4+ T cell regulation of CD25 expression controls development of short-lived effector CD8+ T cells in primary and secondary responses

(2009) J. J. Obar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Notch2 integrates signaling by the transcription factors RBP-J and CREB1 to promote T cell cytotoxicity

(2008) Yoichi Maekawa et al.   NATURE IMMUNOLOGY

It's T-ALL about Notch

(2008) R M Demarest et al.   ONCOGENE

AIP4/Itch Regulates Notch Receptor Degradation in the Absence of Ligand

(2008) Patricia Chastagner et al.   PLoS One