AIG1 and ADTRP are atypical integral membrane hydrolases that degrade bioactive FAHFAs

Chemical Tools for the Study of Intramembrane Proteases

(2015) Minh T. N. Nguyen et al.   ACS Chemical Biology

Selective N-Hydroxyhydantoin Carbamate Inhibitors of Mammalian Serine Hydrolases

(2015) Armand B. Cognetta et al.   CHEMISTRY & BIOLOGY

Immunomodulatory lysophosphatidylserines are regulated by ABHD16A and ABHD12 interplay

(2015) Siddhesh S Kamat et al.   Nature Chemical Biology

Enzyme Inhibitor Discovery by Activity-Based Protein Profiling

(2014) Micah J. Niphakis et al.   Annual Review of Biochemistry

Current Developments in Activity-Based Protein Profiling

(2014) Lianne I. Willems et al.   BIOCONJUGATE CHEMISTRY

Discovery of a Class of Endogenous Mammalian Lipids with Anti-Diabetic and Anti-inflammatory Effects

(2014) Mark M. Yore et al.   CELL

Activity-based probes for rhomboid proteases discovered in a mass spectrometry-based assay

(2013) O. Vosyka et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Activity-Based Protein Profiling of the Escherichia coli GlpG Rhomboid Protein Delineates the Catalytic Core

(2012) Allison R. Sherratt et al.   BIOCHEMISTRY

Confirming Target Engagement for Reversible Inhibitors in Vivo by Kinetically Tuned Activity-Based Probes

(2012) Alexander Adibekian et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

DAGLβ inhibition perturbs a lipid network involved in macrophage inflammatory responses

(2012) Ku-Lung Hsu et al.   Nature Chemical Biology

The Enzyme Function Initiative

(2011) John A. Gerlt et al.   BIOCHEMISTRY

Novel protein ADTRP regulates TFPI expression and function in human endothelial cells in normal conditions and in response to androgen

(2011) C. Lupu et al.   BLOOD

The Metabolic Serine Hydrolases and Their Functions in Mammalian Physiology and Disease

(2011) Jonathan Z. Long et al.   CHEMICAL REVIEWS

Monoacylglycerol Lipase Exerts Dual Control over Endocannabinoid and Fatty Acid Pathways to Support Prostate Cancer

(2011) Daniel K. Nomura et al.   CHEMISTRY & BIOLOGY

Divergence and Convergence in Enzyme Evolution: Parallel Evolution of Paraoxonases from Quorum-quenching Lactonases

(2011) Mikael Elias et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Substrate-Free Activity-Based Protein Profiling Screen for the Discovery of Selective PREPL Inhibitors

(2011) Anna Mari Lone et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Click-generated triazole ureas as ultrapotent in vivo–active serine hydrolase inhibitors

(2011) Alexander Adibekian et al.   Nature Chemical Biology

Activity-based Proteomics of Enzyme Superfamilies: Serine Hydrolases as a Case Study

(2010) Gabriel M. Simon et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Activity-Based Probes That Target Functional Subclasses of Phospholipases in Proteomes

(2010) Sarah E. Tully et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Quantitative reactivity profiling predicts functional cysteines in proteomes

(2010) Eranthie Weerapana et al.   NATURE

Superfamily-wide portrait of serine hydrolase inhibition achieved by library-versus-library screening

(2010) D. A. Bachovchin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Intramembrane-cleaving Proteases

(2009) Michael S. Wolfe   JOURNAL OF BIOLOGICAL CHEMISTRY

Detergent binding explains anomalous SDS-PAGE migration of membrane proteins

(2009) Arianna Rath et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Selectivity of inhibitors of endocannabinoid biosynthesis evaluated by activity-based protein profiling

(2008) Heather S. Hoover et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Unconventional serine proteases: Variations on the catalytic Ser/His/Asp triad configuration

(2008) Özlem Doğan Ekici et al.   PROTEIN SCIENCE