Click-generated triazole ureas as ultrapotent in vivo–active serine hydrolase inhibitors

Acylating drugs: redesigning natural covalent inhibitors

(2010) Arthur F Kluge et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Strategies for discovering and derisking covalent, irreversible enzyme inhibitors

(2010) Douglas S Johnson et al.   Future Medicinal Chemistry

Activity-based Protein Profiling Identifies a Host Enzyme, Carboxylesterase 1, Which Is Differentially Active during Hepatitis C Virus Replication

(2010) David R. Blais et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Activity-based Proteomics of Enzyme Superfamilies: Serine Hydrolases as a Case Study

(2010) Gabriel M. Simon et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Profiling ofN-Acetylated Protein Termini Provides In-depth Insights into the N-terminal Nature of the Proteome

(2010) Andreas O. Helbig et al.   MOLECULAR & CELLULAR PROTEOMICS

Rethinking screening

(2010) Thomas Kodadek   Nature Chemical Biology

Superfamily-wide portrait of serine hydrolase inhibition achieved by library-versus-library screening

(2010) D. A. Bachovchin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Monoacylglycerol Lipase Regulates a Fatty Acid Network that Promotes Cancer Pathogenesis

(2009) Daniel K. Nomura et al.   CELL

Diversity of Serine Hydrolase Activities of Unchallenged andBotrytis-infectedArabidopsis thaliana

(2009) Farnusch Kaschani et al.   MOLECULAR & CELLULAR PROTEOMICS

Dual blockade of FAAH and MAGL identifies behavioral processes regulated by endocannabinoid crosstalk in vivo

(2009) J. Z. Long et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identifying the proteins to which small-molecule probes and drugs bind in cells

(2009) S.-E. Ong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Activity-Based Protein Profiling: From Enzyme Chemistry to Proteomic Chemistry

(2008) Benjamin F. Cravatt et al.   Annual Review of Biochemistry

The genomic basis of the Williams – Beuren syndrome

(2008) C. Schubert   CELLULAR AND MOLECULAR LIFE SCIENCES

Selective blockade of 2-arachidonoylglycerol hydrolysis produces cannabinoid behavioral effects

(2008) Jonathan Z Long et al.   Nature Chemical Biology