Overactivation of GnRH neurons is sufficient to trigger polycystic ovary syndrome-like traits in female mice
出版年份 2023 全文链接
标题
Overactivation of GnRH neurons is sufficient to trigger polycystic ovary syndrome-like traits in female mice
作者
关键词
-
出版物
EBioMedicine
Volume 97, Issue -, Pages 104850
出版商
Elsevier BV
发表日期
2023-10-27
DOI
10.1016/j.ebiom.2023.104850
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- AMH as part of the diagnostic PCOS workup in large epidemiological studies
- (2023) Terhi T Piltonen et al. EUROPEAN JOURNAL OF ENDOCRINOLOGY
- Changes in circulating forms of anti-Muüllerian hormone and androgens in women with and without PCOS: a systematic longitudinal study throughout pregnancy
- (2023) M Peigné et al. HUMAN REPRODUCTION
- Hypothalamic neuroglial plasticity is regulated by anti-Müllerian hormone and disrupted in polycystic ovary syndrome
- (2023) Anne-Laure Barbotin et al. EBioMedicine
- Female sexual behavior is disrupted in a preclinical mouse model of PCOS via an attenuated hypothalamic nitric oxide pathway
- (2022) Mauro S. B. Silva et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- GnRH replacement rescues cognition in Down syndrome
- (2022) Maria Manfredi-Lozano et al. SCIENCE
- Polycystic ovary syndrome is transmitted via a transgenerational epigenetic process
- (2021) Nour El Houda Mimouni et al. Cell Metabolism
- Neurokinin 3 receptor antagonism ameliorates key metabolic features in a hyperandrogenic PCOS mouse model
- (2021) Irene E Sucquart et al. ENDOCRINOLOGY
- Circulating kisspeptin and anti-müllerian hormone levels, and insulin resistance in women with polycystic ovary syndrome: A systematic review, meta-analysis, and meta-regression
- (2021) Faustino R. Pérez-López et al. European Journal of Obstetrics & Gynecology and Reproductive Biology
- Reproductive Deficits Induced by Prenatal Anti-Mullerian Hormone Exposure Require Androgen Receptor in Kisspeptin Cells
- (2021) Emily V Ho et al. ENDOCRINOLOGY
- Prenatal Androgen Exposure Alters KNDy Neurons and Their Afferent Network in a Model of Polycystic Ovarian Syndrome
- (2021) Aleisha M Moore et al. ENDOCRINOLOGY
- Inhibiting Kiss1 Neurons with Kappa Opioid Receptor Agonists to Treat Polycystic Ovary Syndrome and Vasomotor Symptoms
- (2021) Elizabeth A McCarthy et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Targeting Elevated GnRH Pulsatility to Treat Polycystic Ovary Syndrome
- (2021) Ali Abbara et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Health Care-Related Economic Burden of Polycystic Ovary Syndrome in the United States: Pregnancy-Related and Long-Term Health Consequences
- (2021) Carrie Riestenberg et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- New insights into anti-Müllerian hormone role in the hypothalamic–pituitary–gonadal axis and neuroendocrine development
- (2020) Mauro S. B. Silva et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Kisspeptin and neurokinin B interactions in modulating gonadotropin secretion in women with polycystic ovary syndrome
- (2020) Karolina Skorupskaite et al. HUMAN REPRODUCTION
- Distinct subtypes of polycystic ovary syndrome with novel genetic associations: An unsupervised, phenotypic clustering analysis
- (2020) Matthew Dapas et al. PLOS MEDICINE
- Chemogenetic Suppression of GnRH Neurons during Pubertal Development Can Alter Adult GnRH Neuron Firing Rate and Reproductive Parameters in Female Mice
- (2020) Eden A. Dulka et al. eNeuro
- Circulating antimüllerian hormone and steroid hormone levels remain high in pregnant women with polycystic ovary syndrome at term
- (2019) Terhi T. Piltonen et al. FERTILITY AND STERILITY
- Activation of arcuate nucleus GABA neurons promotes luteinizing hormone secretion and reproductive dysfunction: Implications for polycystic ovary syndrome
- (2019) Mauro S.B. Silva et al. EBioMedicine
- Recommendations for epidemiologic and phenotypic research in polycystic ovary syndrome: an androgen excess and PCOS society resource
- (2019) Ricardo Azziz et al. HUMAN REPRODUCTION
- Kisspeptin treatment induces gonadotropic responses and rescues ovulation in a subset of preclinical models and women with polycystic ovary syndrome
- (2019) A Romero-Ruiz et al. HUMAN REPRODUCTION
- Androgen Excess- Polycystic Ovary Syndrome Society: position statement on depression, anxiety, quality of life, and eating disorders in polycystic ovary syndrome
- (2018) Anuja Dokras et al. FERTILITY AND STERILITY
- Recommendations from the international evidence-based guideline for the assessment and management of polycystic ovary syndrome†‡
- (2018) Helena J Teede et al. HUMAN REPRODUCTION
- Elevated prenatal anti-Müllerian hormone reprograms the fetus and induces polycystic ovary syndrome in adulthood
- (2018) Brooke Tata et al. NATURE MEDICINE
- New Perspectives on the Pathogenesis of PCOS: Neuroendocrine Origins
- (2018) Kirsty A. Walters et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
- Higher luteinizing hormone levels associated with antimüllerian hormone in postmenarchal daughters of women with polycystic ovary syndrome
- (2018) Nicolás Crisosto et al. FERTILITY AND STERILITY
- FSH inhibits AMH to support ovarian estradiol synthesis in infantile mice
- (2018) Marie M Devillers et al. JOURNAL OF ENDOCRINOLOGY
- High prevalence of moderate and severe depressive and anxiety symptoms in polycystic ovary syndrome: a systematic review and meta-analysis
- (2017) Laura G. Cooney et al. HUMAN REPRODUCTION
- Neuroendocrine androgen action is a key extraovarian mediator in the development of polycystic ovary syndrome
- (2017) Aimee S. L. Caldwell et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Mapping of Brain Activity by Automated Volume Analysis of Immediate Early Genes
- (2016) Nicolas Renier et al. CELL
- Development of the neurons controlling fertility in humans: new insights from 3D imaging and transparent fetal brains
- (2016) Filippo Casoni et al. DEVELOPMENT
- Pulse and Surge Profiles of Luteinizing Hormone Secretion in the Mouse
- (2016) Katja Czieselsky et al. ENDOCRINOLOGY
- Criteria, prevalence, and phenotypes of polycystic ovary syndrome
- (2016) Daria Lizneva et al. FERTILITY AND STERILITY
- Overweight and obese but not normal weight women with PCOS are at increased risk of Type 2 diabetes mellitus—a prospective, population-based cohort study
- (2016) M.-M.E. Ollila et al. HUMAN REPRODUCTION
- Interactions between androgens, FSH, anti-Müllerian hormone and estradiol during folliculogenesis in the human normal and polycystic ovary
- (2016) Didier Dewailly et al. HUMAN REPRODUCTION UPDATE
- Novel role for anti-Müllerian hormone in the regulation of GnRH neuron excitability and hormone secretion
- (2016) Irene Cimino et al. Nature Communications
- Haplosufficient Genomic Androgen Receptor Signaling Is Adequate to Protect Female Mice From Induction of Polycystic Ovary Syndrome Features by Prenatal Hyperandrogenization
- (2015) A.S.L. Caldwell et al. ENDOCRINOLOGY
- Hirsutism and oligomenorrhea are appropriate screening criteria for polycystic ovary syndrome in adolescents
- (2015) Claudio Villarroel et al. GYNECOLOGICAL ENDOCRINOLOGY
- 60 YEARS OF NEUROENDOCRINOLOGY: The hypothalamo-pituitary–gonadal axis
- (2015) Tony M Plant JOURNAL OF ENDOCRINOLOGY
- Selective optogenetic activation of arcuate kisspeptin neurons generates pulsatile luteinizing hormone secretion
- (2015) Su Young Han et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Irregular menstruation and hyperandrogenaemia in adolescence are associated with polycystic ovary syndrome and infertility in later life: Northern Finland Birth Cohort 1986 study
- (2014) S. West et al. HUMAN REPRODUCTION
- Prenatal androgen excess enhances stimulation of the GNRH pulse in pubertal female rats
- (2014) Xiaonan Yan et al. JOURNAL OF ENDOCRINOLOGY
- Optogenetic activation of GnRH neurons reveals minimal requirements for pulsatile luteinizing hormone secretion
- (2014) Pauline Campos et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Enhancement of a robust arcuate GABAergic input to gonadotropin-releasing hormone neurons in a model of polycystic ovarian syndrome
- (2014) Aleisha M. Moore et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Development of a Methodology for and Assessment of Pulsatile Luteinizing Hormone Secretion in Juvenile and Adult Male Mice
- (2013) F. J. Steyn et al. ENDOCRINOLOGY
- Kisspeptin, Neurokinin B, and Dynorphin Act in the Arcuate Nucleus to Control Activity of the GnRH Pulse Generator in Ewes
- (2013) Robert L. Goodman et al. ENDOCRINOLOGY
- Ontogeny of the ovary in polycystic ovary syndrome
- (2013) Daniel A. Dumesic et al. FERTILITY AND STERILITY
- Antimüllerian hormone inhibits follicle-stimulating hormone-induced adenylyl cyclase activation, aromatase expression, and estradiol production in human granulosa-lutein cells
- (2013) Hsun-Ming Chang et al. FERTILITY AND STERILITY
- GnRH pulse frequency-dependent differential regulation of LH and FSH gene expression
- (2013) Iain R. Thompson et al. MOLECULAR AND CELLULAR ENDOCRINOLOGY
- Evidence That Dopamine Acts via Kisspeptin to Hold GnRH Pulse Frequency in Check in Anestrous Ewes
- (2012) Robert L. Goodman et al. ENDOCRINOLOGY
- Arcuate Kisspeptin/Neurokinin B/Dynorphin (KNDy) Neurons Mediate the Estrogen Suppression of Gonadotropin Secretion and Body Weight
- (2012) Melinda A. Mittelman-Smith et al. ENDOCRINOLOGY
- Polycystic ovary syndrome: etiology, pathogenesis and diagnosis
- (2011) Mark O. Goodarzi et al. Nature Reviews Endocrinology
- Dynamics of extracellular matrix in ovarian follicles and corpora lutea of mice
- (2009) Helen F. Irving-Rodgers et al. CELL AND TISSUE RESEARCH
- Modulation of Gonadotropin-Releasing Hormone Pulse Generator Sensitivity to Progesterone Inhibition in Hyperandrogenic Adolescent Girls—Implications for Regulation of Pubertal Maturation
- (2009) Susan K. Blank et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Regulation of Gonadotropin-Releasing Hormone Secretion by Kisspeptin/Dynorphin/Neurokinin B Neurons in the Arcuate Nucleus of the Mouse
- (2009) V. M. Navarro et al. JOURNAL OF NEUROSCIENCE
- Inappropriate gonadotropin secretion in polycystic ovary syndrome
- (2008) Ming-I Hsu et al. FERTILITY AND STERILITY
- Suppression and recovery of gonadotropin and steroid secretion by a gonadotropin-releasing hormone receptor antagonist in healthy women with normal ovulation versus women with polycystic ovary syndrome in the early follicular phase
- (2008) Francesca Sagnella et al. FERTILITY AND STERILITY
- Follicle dynamics and anovulation in polycystic ovary syndrome
- (2008) S. Franks et al. HUMAN REPRODUCTION UPDATE
- Maturation of Luteinizing Hormone (Gonadotropin-Releasing Hormone) Secretion across Puberty: Evidence for Altered Regulation in Obese Peripubertal Girls
- (2008) Christopher R. McCartney et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started