标题
Polycystic ovary syndrome is transmitted via a transgenerational epigenetic process
作者
关键词
PCOS, transgenerational, inheritance, epigenetics, methylation, neuroendocrine, AMH, fertility, metabolic disorder, developmental programming
出版物
Cell Metabolism
Volume 33, Issue 3, Pages 513-530.e8
出版商
Elsevier BV
发表日期
2021-02-06
DOI
10.1016/j.cmet.2021.01.004
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Animal models to understand the etiology and pathophysiology of polycystic ovary syndrome
- (2020) Elisabet Stener-Victorin et al. ENDOCRINE REVIEWS
- Adipose Insulin Resistance in Normal-Weight Polycystic Ovary Syndrome Women
- (2019) Daniel A Dumesic et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- DNA Methylation Reprogramming during Mammalian Development
- (2019) Yang Zeng et al. Genes
- Functional Genetic Variation in the Anti-Müllerian Hormone Pathway in Women with Polycystic Ovary Syndrome
- (2019) Lidija K Gorsic et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Advances in epigenetics link genetics to the environment and disease
- (2019) Giacomo Cavalli et al. NATURE
- Gut microbiota–bile acid–interleukin-22 axis orchestrates polycystic ovary syndrome
- (2019) Xinyu Qi et al. NATURE MEDICINE
- DNA methylation in the pathogenesis of polycystic ovary syndrome
- (2019) Edgar Ricardo Vázquez-Martínez et al. REPRODUCTION
- Genome-wide methylation profiling in granulosa lutein cells of women with polycystic ovary syndrome (PCOS)
- (2019) E. Makrinou et al. MOLECULAR AND CELLULAR ENDOCRINOLOGY
- Prenatal androgen exposure and transgenerational susceptibility to polycystic ovary syndrome
- (2019) Sanjiv Risal et al. NATURE MEDICINE
- Polycystic ovary syndrome (PCOS), an inflammatory, systemic, lifestyle endocrinopathy
- (2018) Seema Patel JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY
- Elevated prenatal anti-Müllerian hormone reprograms the fetus and induces polycystic ovary syndrome in adulthood
- (2018) Brooke Tata et al. NATURE MEDICINE
- Polycystic ovary syndrome: definition, aetiology, diagnosis and treatment
- (2018) Héctor F. Escobar-Morreale Nature Reviews Endocrinology
- Consistent inverse correlation between DNA methylation of the first intron and gene expression across tissues and species
- (2018) Dafni Anastasiadi et al. Epigenetics & Chromatin
- Aberrant expression and DNA methylation of lipid metabolism genes in PCOS: a new insight into its pathogenesis
- (2018) Jie-Xue Pan et al. Clinical Epigenetics
- New Perspectives on the Pathogenesis of PCOS: Neuroendocrine Origins
- (2018) Kirsty A. Walters et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
- Higher luteinizing hormone levels associated with antimüllerian hormone in postmenarchal daughters of women with polycystic ovary syndrome
- (2018) Nicolás Crisosto et al. FERTILITY AND STERILITY
- Gaps in knowledge among physicians regarding diagnostic criteria and management of polycystic ovary syndrome
- (2017) Anuja Dokras et al. FERTILITY AND STERILITY
- Pathogenic Anti-Müllerian Hormone Variants in Polycystic Ovary Syndrome
- (2017) Lidija K Gorsic et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Hypothalamic inflammation in obesity and metabolic disease
- (2017) Alexander Jais et al. JOURNAL OF CLINICAL INVESTIGATION
- Adapting to obesity with adipose tissue inflammation
- (2017) Shannon M. Reilly et al. Nature Reviews Endocrinology
- Neuroendocrine androgen action is a key extraovarian mediator in the development of polycystic ovary syndrome
- (2017) Aimee S. L. Caldwell et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Intrauterine Reprogramming of the Polycystic Ovary Syndrome: Evidence from a Pilot Study of Cord Blood Global Methylation Analysis
- (2017) Luca Lambertini et al. Frontiers in Endocrinology
- Insulin signalling and glucose transport in the ovary and ovarian function during the ovarian cycle
- (2016) J. Dupont et al. BIOCHEMICAL JOURNAL
- Data-driven hypothesis weighting increases detection power in genome-scale multiple testing
- (2016) Nikolaos Ignatiadis et al. NATURE METHODS
- Refining diagnostic features in PCOS to optimize health outcomes
- (2016) Jacqueline A. Boyle et al. Nature Reviews Endocrinology
- Erratum: PCOS in 2015: New insights into the genetics of polycystic ovary syndrome
- (2016) Ricardo Azziz Nature Reviews Endocrinology
- Comprehensive analysis of genome-wide DNA methylation across human polycystic ovary syndrome ovary granulosa cell
- (2016) Jiawei Xu et al. Oncotarget
- Single-cell analysis of differences in transcriptomic profiles of oocytes and cumulus cells at GV, MI, MII stages from PCOS patients
- (2016) Qiwei Liu et al. Scientific Reports
- Scientific Statement on the Diagnostic Criteria, Epidemiology, Pathophysiology, and Molecular Genetics of Polycystic Ovary Syndrome
- (2015) Daniel A. Dumesic et al. ENDOCRINE REVIEWS
- Genome-wide screen of ovary-specific DNA methylation in polycystic ovary syndrome
- (2015) Ying-Ying Yu et al. FERTILITY AND STERILITY
- Up-Regulated Expression of WNT5a Increases Inflammation and Oxidative Stress via PI3K/AKT/NF-κB Signaling in the Granulosa Cells of PCOS Patients
- (2015) Yue Zhao et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Functional genomics of PCOS: from GWAS to molecular mechanisms
- (2015) Jan M. McAllister et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
- Genome-wide DNA methylation and gene expression patterns provide insight into polycystic ovary syndrome development
- (2015) Xiu-Xia Wang et al. Oncotarget
- Early life epigenetic programming and transmission of stress-induced traits in mammals
- (2014) Katharina Gapp et al. BIOESSAYS
- HTSeq--a Python framework to work with high-throughput sequencing data
- (2014) S. Anders et al. BIOINFORMATICS
- iDISCO: A Simple, Rapid Method to Immunolabel Large Tissue Samples for Volume Imaging
- (2014) Nicolas Renier et al. CELL
- svaseq: removing batch effects and other unwanted noise from sequencing data
- (2014) Jeffrey T. Leek NUCLEIC ACIDS RESEARCH
- Enhancement of a robust arcuate GABAergic input to gonadotropin-releasing hormone neurons in a model of polycystic ovarian syndrome
- (2014) Aleisha M. Moore et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A Simple Method for 3D Analysis of Immunolabeled Axonal Tracts in a Transparent Nervous System
- (2014) Morgane Belle et al. Cell Reports
- Synergistic anti-breast cancer effect of a combined treatment with the methyl donorS-adenosyl methionine and the DNA methylation inhibitor 5-aza-2′-deoxycytidine
- (2013) Flora Chik et al. CARCINOGENESIS
- Development of a Methodology for and Assessment of Pulsatile Luteinizing Hormone Secretion in Juvenile and Adult Male Mice
- (2013) F. J. Steyn et al. ENDOCRINOLOGY
- Genome-Wide Methylated DNA Immunoprecipitation Analysis of Patients with Polycystic Ovary Syndrome
- (2013) Hao-ran Shen et al. PLoS One
- RSeQC: quality control of RNA-seq experiments
- (2012) Liguo Wang et al. BIOINFORMATICS
- STAR: ultrafast universal RNA-seq aligner
- (2012) Alexander Dobin et al. BIOINFORMATICS
- SERE: Single-parameter quality control and sample comparison for RNA-Seq
- (2012) Stefan K Schulze et al. BMC GENOMICS
- Insulin Resistance and the Polycystic Ovary Syndrome Revisited: An Update on Mechanisms and Implications
- (2012) Evanthia Diamanti-Kandarakis et al. ENDOCRINE REVIEWS
- A molecular mechanism underlying ovarian dysfunction of polycystic ovary syndrome: hyperandrogenism induces epigenetic alterations in the granulosa cells
- (2012) Fan Qu et al. JOURNAL OF MOLECULAR MEDICINE-JMM
- Sheep models of polycystic ovary syndrome phenotype
- (2012) Vasantha Padmanabhan et al. MOLECULAR AND CELLULAR ENDOCRINOLOGY
- Relationship Between Anti-Müllerian Hormone (AMH) and Insulin Levels During Different Tanner Stages in Daughters of Women With Polycystic Ovary Syndrome
- (2012) Teresa Sir-Petermann et al. Reproductive Sciences
- Effects of S -adenosylmethionine and methylthioadenosine on inflammation-induced colon cancer in mice
- (2011) Tony W.H. Li et al. CARCINOGENESIS
- Does PCOS have developmental origins?
- (2011) Stephen Franks et al. FERTILITY AND STERILITY
- CpG islands and the regulation of transcription
- (2011) A. M. Deaton et al. GENES & DEVELOPMENT
- Diagnosis of polycystic ovary syndrome (PCOS): revisiting the threshold values of follicle count on ultrasound and of the serum AMH level for the definition of polycystic ovaries
- (2011) D. Dewailly et al. HUMAN REPRODUCTION
- DNA Methylation of the First Exon Is Tightly Linked to Transcriptional Silencing
- (2011) Fabienne Brenet et al. PLoS One
- Epigenetic Mechanism Underlying the Development of Polycystic Ovary Syndrome (PCOS)-Like Phenotypes in Prenatally Androgenized Rhesus Monkeys
- (2011) Ning Xu et al. PLoS One
- BEDTools: a flexible suite of utilities for comparing genomic features
- (2010) Aaron R. Quinlan et al. BIOINFORMATICS
- Assessment of Cardiovascular Risk and Prevention of Cardiovascular Disease in Women with the Polycystic Ovary Syndrome: A Consensus Statement by the Androgen Excess and Polycystic Ovary Syndrome (AE-PCOS) Society
- (2010) Robert A. Wild et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- The ovary: basic biology and clinical implications
- (2010) JoAnne S. Richards et al. JOURNAL OF CLINICAL INVESTIGATION
- Prenatal androgen exposure programs metabolic dysfunction in female mice
- (2010) Alison V Roland et al. JOURNAL OF ENDOCRINOLOGY
- Simple Combinations of Lineage-Determining Transcription Factors Prime cis-Regulatory Elements Required for Macrophage and B Cell Identities
- (2010) Sven Heinz et al. MOLECULAR CELL
- Epigenetic modifications as therapeutic targets
- (2010) Theresa K Kelly et al. NATURE BIOTECHNOLOGY
- Differential expression analysis for sequence count data
- (2010) Simon Anders et al. GENOME BIOLOGY
- Epigenetics in polycystic ovary syndrome: a pilot study of global DNA methylation
- (2009) Ning Xu et al. FERTILITY AND STERILITY
- The prevalence of polycystic ovary syndrome in a community sample assessed under contrasting diagnostic criteria
- (2009) W. A. March et al. HUMAN REPRODUCTION
- Ultrafast and memory-efficient alignment of short DNA sequences to the human genome
- (2009) Ben Langmead et al. GENOME BIOLOGY
- Model-based Analysis of ChIP-Seq (MACS)
- (2008) Yong Zhang et al. GENOME BIOLOGY
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