A new look at Hsp70 activity in phosphatidylserine-enriched membranes: chaperone-induced quasi-interdigitated lipid phase

Heat Shock Proteins and Ferroptosis

(2022) Ying Liu et al.   Frontiers in Cell and Developmental Biology

The interaction of heat shock proteins with cellular membranes: a historical perspective

(2021) Antonio De Maio et al.   CELL STRESS & CHAPERONES

Shiga Toxins as Antitumor Tools

(2021) Aude Robert et al.   Toxins

Heat shock proteins in cell signaling and cancer

(2021) Benjamin J. Lang et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Membrane-Associated Heat Shock Proteins in Oncology: From Basic Research to New Theranostic Targets

(2020) Maxim Shevtsov et al.   Cells

Hsp70-mediated quality control: should I stay or should I go?

(2020) Verena Kohler et al.   BIOLOGICAL CHEMISTRY

Characterization of the Relationship between the Chaperone and Lipid-Binding Functions of the 70-kDa Heat-Shock Protein, HspA1A

(2020) Larissa Smulders et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Granzyme B Functionalized Nanoparticles Targeting Membrane Hsp70‐Positive Tumors for Multimodal Cancer Theranostics

(2019) Maxim Shevtsov et al.   Small

Hsp70 interactions with membrane lipids regulate cellular functions in health and disease

(2019) Zsolt Balogi et al.   PROGRESS IN LIPID RESEARCH

Interdigitation of Lipids Induced by Membrane–Active Proteins

(2019) T. Devanand et al.   JOURNAL OF MEMBRANE BIOLOGY

Membrane Localization of HspA1A, a Stress Inducible 70-kDa Heat-Shock Protein, Depends on Its Interaction with Intracellular Phosphatidylserine

(2019) Bilog et al.   Biomolecules

Flippase and scramblase for phosphatidylserine exposure

(2019) Shigekazu Nagata et al.   CURRENT OPINION IN IMMUNOLOGY

Lipid-mediated regulation of pore-forming activity of syringomycin E by thyroid hormones and xanthene dyes

(2018) Svetlana S. Efimova et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Molecular AFM imaging of Hsp70-1A association with dipalmitoyl phosphatidylserine reveals membrane blebbing in the presence of cholesterol

(2018) Constanze Lamprecht et al.   CELL STRESS & CHAPERONES

Order and disorder in the physiological membrane binding of α-synuclein

(2018) Giuliana Fusco et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

The Hsp70–Hsp90 Chaperone Cascade in Protein Folding

(2018) Tania Morán Luengo et al.   TRENDS IN CELL BIOLOGY

Overexpression of cytosolic, plasma membrane bound and extracellular heat shock protein 70 (Hsp70) in primary glioblastomas

(2017) Jun Thorsteinsdottir et al.   JOURNAL OF NEURO-ONCOLOGY

Influence of doxorubicin on model cell membrane properties: insights from in vitro and in silico studies

(2017) Ana Catarina Alves et al.   Scientific Reports

Phloretin increases the anti-tumor efficacy of intratumorally delivered heat-shock protein 70 kDa (HSP70) in a murine model of melanoma

(2015) Sergey V. Abkin et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Biochemical characterization of the interaction between HspA1A and phospholipids

(2015) Chelsea McCallister et al.   CELL STRESS & CHAPERONES

Cross-linking of glycosphingolipids at the plasma membrane: consequences for intracellular signaling and traffic

(2015) Tove Irene Klokk et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Inhibition of acid sphingomyelinase depletes cellular phosphatidylserine and mislocalizes K-Ras from the plasma membrane

(2015) Kwang-jin Cho et al.   MOLECULAR AND CELLULAR BIOLOGY

Variation in human cancer cell external phosphatidylserine is regulated by flippase activity and intracellular calcium

(2015) Subrahmanya D. Vallabhapurapu et al.   Oncotarget

Human heat shock protein 70 (Hsp70) as a peripheral membrane protein

(2014) Ajay K. Mahalka et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Interaction of heat shock protein 70 with membranes depends on the lipid environment

(2014) Gabrielle Armijo et al.   CELL STRESS & CHAPERONES

Effective immunotherapy of rat glioblastoma with prolonged intratumoral delivery of exogenous heat shock protein Hsp70

(2014) Maxim A. Shevtsov et al.   INTERNATIONAL JOURNAL OF CANCER

Hsp70 Translocates into the Plasma Membrane after Stress and Is Released into the Extracellular Environment in a Membrane-Associated Form that Activates Macrophages

(2014) V. L. Vega et al.   JOURNAL OF IMMUNOLOGY

Molecular lipidomics of exosomes released by PC-3 prostate cancer cells

(2013) Alicia Llorente et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

The HSP70 family and cancer

(2013) M. E. Murphy   CARCINOGENESIS

Effect of flavonoids on the phase separation in giant unilamellar vesicles formed from binary lipid mixtures

(2013) Olga S. Ostroumova et al.   CHEMISTRY AND PHYSICS OF LIPIDS

α-Synuclein Senses Lipid Packing Defects and Induces Lateral Expansion of Lipids Leading to Membrane Remodeling

(2013) Myriam M. Ouberai et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Immunotherapeutic Targeting of Membrane Hsp70-Expressing Tumors Using Recombinant Human Granzyme B

(2012) Mathias Gehrmann et al.   PLoS One

Phosphatidylserine is a critical modulator for Akt activation

(2011) Bill X. Huang et al.   JOURNAL OF CELL BIOLOGY

Association of heat-shock protein 70 with lipid rafts is required for Japanese encephalitis virus infection in Huh7 cells

(2011) Y.-Z. Zhu et al.   JOURNAL OF GENERAL VIROLOGY

α-Synuclein-Induced Tubule Formation in Lipid Bilayers

(2011) Anjan P. Pandey et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Phosphatidylserine is polarized and required for proper Cdc42 localization and for development of cell polarity

(2011) Gregory D. Fairn et al.   NATURE CELL BIOLOGY

Fluorescent probe partitioning in giant unilamellar vesicles of ‘lipid raft’ mixtures

(2010) Janos Juhasz et al.   BIOCHEMICAL JOURNAL

Extracellular heat shock proteins, cellular export vesicles, and the Stress Observation System: A form of communication during injury, infection, and cell damage

(2010) Antonio De Maio   CELL STRESS & CHAPERONES

Membrane Curvature Induction and Tubulation Are Common Features of Synucleins and Apolipoproteins

(2010) Jobin Varkey et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hsp12 Is an Intrinsically Unstructured Stress Protein that Folds upon Membrane Association and Modulates Membrane Function

(2010) Sylvia Welker et al.   MOLECULAR CELL

Protein folding at the membrane interface, the structure of Nogo-66 requires interactions with a phosphocholine surface

(2010) S. V. Vasudevan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

New aspects of the regulation of glycosphingolipid receptor function

(2009) Clifford A. Lingwood et al.   CHEMISTRY AND PHYSICS OF LIPIDS

Binding of heat shock protein 70 to extracellular phosphatidylserine promotes killing of normoxic and hypoxic tumor cells

(2009) Daniela Schilling et al.   FASEB JOURNAL

Structural Properties of Pore-Forming Oligomers of α-Synuclein

(2009) Hai-Young Kim et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Interaction of the P-Glycoprotein Multidrug Efflux Pump with Cholesterol: Effects on ATPase Activity, Drug Binding and Transport†

(2008) Paul D. W. Eckford et al.   BIOCHEMISTRY

Membrane Thickening by the Antimicrobial Peptide PGLa

(2008) Georg Pabst et al.   BIOPHYSICAL JOURNAL

Interaction of LL-37 with Model Membrane Systems of Different Complexity: Influence of the Lipid Matrix

(2008) E. Sevcsik et al.   BIOPHYSICAL JOURNAL

Tumor-Specific Hsp70 Plasma Membrane Localization Is Enabled by the Glycosphingolipid Gb3

(2008) Mathias Gehrmann et al.   PLoS One