Merging Iridium-Catalyzed Stereoselective Coupling from Alcohols with Organocatalytic Functionalization at the Aldehyde Oxidation Level

Asymmetric Ruthenium-Catalyzed Carbonyl Allylations by Gaseous Allene via Hydrogen Auto-Transfer: 1° versus 2° Alcohol Dehydrogenation for Streamlined Polyketide Construction

(2023) Connor Saludares et al.   ACS Catalysis

Organo/Transition-Metal Combined Catalysis Rejuvenates Both in Asymmetric Synthesis

(2022) Dian-Feng Chen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Asymmetric Ruthenium‐Catalyzed Hydroalkylation of Racemic Allylic Alcohols for the Synthesis of Chiral Amino Acid Derivatives

(2022) Xiaohui Zhang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Manganese‐Catalyzed Asymmetric Formal Hydroamination of Allylic Alcohols: A Remarkable Macrocyclic Ligand Effect

(2022) Faju Li et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Stereodivergent Construction of 1,4‐Nonadjacent Stereocenters via Hydroalkylation of Racemic Allylic Alcohols Enabled by Copper/Ruthenium Relay Catalysis

(2022) Xin Chang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

From Hydrogenation to Transfer Hydrogenation to Hydrogen Auto-Transfer in Enantioselective Metal-Catalyzed Carbonyl Reductive Coupling: Past, Present, and Future

(2021) Catherine Gazolla Santana et al.   ACS Catalysis

Challenges and Opportunities in Multicatalysis

(2021) Sebastián Martínez et al.   ACS Catalysis

Borrowing Hydrogen for Organic Synthesis

(2021) Benjamin G. Reed-Berendt et al.   ACS Central Science

Simultaneous Kinetic Resolution and Asymmetric Induction within a Borrowing Hydrogen Cascade Mediated by a Single Catalyst

(2021) Ming Yu Jin et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Iron‐based multi‐catalysis: eco‐compatible alternative for complex molecules synthesis

(2020) Adrien Quintard   CHEMISTRY-A EUROPEAN JOURNAL

Anti‐Markovnikov Hydroamination of Racemic Allylic Alcohols to Access Chiral γ‐Amino Alcohols

(2020) Ruirui Xu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Asymmetric Synthesis of γ-Secondary Amino Alcohols via a Borrowing-Hydrogen Cascade

(2020) Yupeng Pan et al.   ORGANIC LETTERS

Regio- and Enantioselective Iridium-Catalyzed N-Allylation of Indoles and Related Azoles with Racemic Branched Alkyl-Substituted Allylic Acetates

(2019) Seung Wook Kim et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Advances in One-Pot Synthesis through Borrowing Hydrogen Catalysis

(2018) Avelino Corma et al.   CHEMICAL REVIEWS

Amphiphilic π-Allyliridium C,O-Benzoates Enable Regio- and Enantioselective Amination of Branched Allylic Acetates Bearing Linear Alkyl Groups

(2018) Arismel Tena Meza et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Hydroamination versus Allylic Amination in Iridium-Catalyzed Reactions of Allylic Acetates with Amines: 1,3-Aminoalcohols via Ester-Directed Regioselectivity

(2018) Seung Wook Kim et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Total Syntheses of Thailanstatins A–C, Spliceostatin D, and Analogues Thereof. Stereodivergent Synthesis of Tetrasubstituted Dihydro- and Tetrahydropyrans and Design, Synthesis, Biological Evaluation, and Discovery of Potent Antitumor Agents

(2018) K. C. Nicolaou et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Regio- and Enantioselective Iridium-Catalyzed Amination of Racemic Branched Alkyl-Substituted Allylic Acetates with Primary and Secondary Aromatic and Heteroaromatic Amines

(2018) Seung Wook Kim et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enantioselective Ir-Catalyzed Bidirectional Reductive Coupling

(2018) Adrien Quintard et al.   ORGANIC LETTERS

Stereodivergence in Asymmetric Catalysis

(2017) Simon Krautwald et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Multicatalytic Enantioselective Borrowing Hydrogen δ-Lactonization Strategy from β-Keto Esters and Allylic Alcohols

(2017) Adrien Quintard et al.   SYNTHESIS-STUTTGART

Catalytic enantioselective OFF ↔ ON activation processes initiated by hydrogen transfer: concepts and challenges

(2016) Adrien Quintard et al.   CHEMICAL COMMUNICATIONS

Combinations of Aminocatalysts and Metal Catalysts: A Powerful Cooperative Approach in Selective Organic Synthesis

(2016) Samson Afewerki et al.   CHEMICAL REVIEWS

Enantioselective Alcohol C–H Functionalization for Polyketide Construction: Unlocking Redox-Economy and Site-Selectivity for Ideal Chemical Synthesis

(2016) Jiajie Feng et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Metal-catalyzed reductive coupling of olefin-derived nucleophiles: Reinventing carbonyl addition

(2016) Khoa D. Nguyen et al.   SCIENCE

Triple Iron/Copper/Iminium Activation for the Efficient Redox Neutral Catalytic Enantioselective Functionalization of Allylic Alcohols

(2016) Mylène Roudier et al.   ACS Catalysis

Substitution of alcohols by N-nucleophiles via transition metal-catalyzed dehydrogenation

(2015) Qin Yang et al.   CHEMICAL SOCIETY REVIEWS

Enantioselective cooperative catalysis

(2015) Suleman M. Inamdar et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Catalyst-Directed Diastereo- and Site-Selectivity in Successive Nucleophilic and Electrophilic Allylations of Chiral 1,3-Diols: Protecting-Group-Free Synthesis of Substituted Pyrans

(2014) Inji Shin et al.   CHEMISTRY-A EUROPEAN JOURNAL

Redox-Triggered C–C Coupling of Alcohols and Vinyl Epoxides: Diastereo- and Enantioselective Formation of All-Carbon Quaternary Centers via tert-(Hydroxy)-Prenylation

(2014) Jiajie Feng et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Stereodivergent α-Allylation of Linear Aldehydes with Dual Iridium and Amine Catalysis

(2014) Simon Krautwald et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Synthesis of α,α′-trans-Oxepanes through an Organocatalytic Oxa-conjugate Addition Reaction

(2014) Megan L. Lanier et al.   ORGANIC LETTERS

Enantioselective Cascade Formal Reductive Insertion of Allylic Alcohols into the C(O)–C Bond of 1,3-Diketones: Ready Access to Synthetically Valuable 3-Alkylpentanol Units

(2014) Mylène Roudier et al.   ORGANIC LETTERS

Protecting-Group-Free Diastereoselective CC Coupling of 1,3-Glycols and Allyl Acetate through Site-Selective Primary Alcohol Dehydrogenation

(2013) Anne-Marie R. Dechert-Schmitt et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

An Iron/Amine-Catalyzed Cascade Process for the Enantioselective Functionalization of Allylic Alcohols

(2013) Adrien Quintard et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enantio- and Diastereodivergent Dual Catalysis:  -Allylation of Branched Aldehydes

(2013) S. Krautwald et al.   SCIENCE

Applications of Acceptorless Dehydrogenation and Related Transformations in Chemical Synthesis

(2013) C. Gunanathan et al.   SCIENCE

Organocatalytic Kinetic Resolution Cascade Reactions: New Mechanistic and Stereochemical Manifold in Diphenyl Prolinol Silyl Ether Catalysis

(2012) Patrick G. McGarraugh et al.   CHEMISTRY-A EUROPEAN JOURNAL

Mandelalides A–D, Cytotoxic Macrolides from a New Lissoclinum Species of South African Tunicate

(2012) Justyna Sikorska et al.   JOURNAL OF ORGANIC CHEMISTRY

Stereoselective Synthesis of Tetrahydropyrans through Tandem and Organocatalytic Oxa-Michael Reactions: Synthesis of the Tetrahydropyran Cores of ent-(+)-Sorangicin A

(2011) Kiyoun Lee et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Enhanced anti-Diastereo- and Enantioselectivity in Alcohol-Mediated Carbonyl Crotylation Using an Isolable Single Component Iridium Catalyst

(2011) Xin Gao et al.   JOURNAL OF ORGANIC CHEMISTRY

Direct Generation of Acyclic Polypropionate StereopolyadsviaDouble Diastereo- and Enantioselective Iridium-Catalyzed Crotylation of 1,3-Diols: Beyond Stepwise Carbonyl Addition in Polyketide Construction

(2011) Xin Gao et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

An Organocascade Kinetic Resolution

(2011) Patrick G. McGarraugh et al.   ORGANIC LETTERS

Total Synthesis of (+)-Roxaticin via C−C Bond Forming Transfer Hydrogenation: A Departure from Stoichiometric Chiral Reagents, Auxiliaries, and Premetalated Nucleophiles in Polyketide Construction

(2010) Soo Bong Han et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

1,n-Glycols as Dialdehyde Equivalents in Iridium-Catalyzed Enantioselective Carbonyl Allylation and Iterative Two-Directional Assembly of 1,3-Polyols

(2009) Yu Lu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Redox Economy in Organic Synthesis

(2009) Noah Z. Burns et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The economies of synthesis

(2009) Timothy Newhouse et al.   CHEMICAL SOCIETY REVIEWS

Enantioselective Carbonyl Reverse Prenylation from the Alcohol or Aldehyde Oxidation Level Employing 1,1-Dimethylallene as the Prenyl Donor

(2009) Soo Bong Han et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

anti-Diastereo- and Enantioselective Carbonyl Crotylation from the Alcohol or Aldehyde Oxidation Level Employing a Cyclometallated Iridium Catalyst: α-Methyl Allyl Acetate as a Surrogate to Preformed Crotylmetal Reagents

(2009) In Su Kim et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Elongation of 1,3-Polyols via Iterative Catalyst-Directed Carbonyl Allylation from the Alcohol Oxidation Level

(2009) Abbas Hassan et al.   ORGANIC LETTERS

Organocatalytic Synthesis of an Alkyltetrahydropyran

(2009) D. Díez et al.   SYNLETT

Asymmetric Aminocatalysis-Gold Rush in Organic Chemistry

(2008) Paolo Melchiorre et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enantioselective Iridium-Catalyzed Carbonyl Allylation from the Alcohol or Aldehyde Oxidation Level Using Allyl Acetate as an Allyl Metal Surrogate

(2008) In Su Kim et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enantioselective Iridium-Catalyzed Carbonyl Allylation from the Alcohol or Aldehyde Oxidation Level via Transfer Hydrogenative Coupling of Allyl Acetate: Departure from Chirally Modified Allyl Metal Reagents in Carbonyl Addition

(2008) In Su Kim et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY