Core mitochondrial genes are down-regulated during SARS-CoV-2 infection of rodent and human hosts

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SARS-CoV-2 infection enhances mitochondrial PTP complex activity to perturb cardiac energetics

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A comprehensive SARS-CoV-2 and COVID-19 review, Part 1: Intracellular overdrive for SARS-CoV-2 infection

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SARS-CoV-2 infection in hamsters and humans results in lasting and unique systemic perturbations post recovery

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Evidences for lipid involvement in SARS-CoV-2 cytopathogenesis

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Shotgun transcriptome, spatial omics, and isothermal profiling of SARS-CoV-2 infection reveals unique host responses, viral diversification, and drug interactions

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SARS-CoV-2 ORF9b inhibits RIG-I-MAVS antiviral signaling by interrupting K63-linked ubiquitination of NEMO

(2021) Jing Wu et al.   Cell Reports

Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV

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Coding and non-coding roles of MOCCI (C15ORF48) coordinate to regulate host inflammation and immunity

(2021) Cheryl Q. E. Lee et al.   Nature Communications

SARS-CoV-2 hijacks folate and one-carbon metabolism for viral replication

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SARS-CoV-2 infection rewires host cell metabolism and is potentially susceptible to mTORC1 inhibition

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Association of Mitochondrial Biogenesis With Variable Penetrance of Schizophrenia

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The COVIDome Explorer researcher portal

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An airway organoid-based screen identifies a role for the HIF1α-glycolysis axis in SARS-CoV-2 infection

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Immune system cells from COVID-19 patients display compromised mitochondrial-nuclear expression co-regulation and rewiring toward glycolysis

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Mitochondrial stress is relayed to the cytosol by an OMA1–DELE1–HRI pathway

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A pathway coordinated by DELE1 relays mitochondrial stress to the cytosol

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Proteomics of SARS-CoV-2-infected host cells reveals therapy targets

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A SARS-CoV-2 protein interaction map reveals targets for drug repurposing

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Decoding SARS-CoV-2 hijacking of host mitochondria in COVID-19 pathogenesis

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Elevated Glucose Levels Favor SARS-CoV-2 Infection and Monocyte Response through a HIF-1α/Glycolysis-Dependent Axis

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(2020) He-wei Jiang et al.   Nature Communications

A Mouse-Adapted SARS-CoV-2 Induces Acute Lung Injury and Mortality in Standard Laboratory Mice

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Integrative Imaging Reveals SARS-CoV-2-Induced Reshaping of Subcellular Morphologies

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A cross-talk between epithelium and endothelium mediates human alveolar–capillary injury during SARS-CoV-2 infection

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Clinical and Functional Relevance of the Monocarboxylate Transporter Family in Disease Pathophysiology and Drug Therapy

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The small molecule ISRIB rescues the stability and activity of Vanishing White Matter Disease eIF2B mutant complexes

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Mitochondrial double-stranded RNA triggers antiviral signalling in humans

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New mitochondrial DNA synthesis enables NLRP3 inflammasome activation

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Multi-omics analysis identifies ATF4 as a key regulator of the mitochondrial stress response in mammals

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