The small molecule ISRIB rescues the stability and activity of Vanishing White Matter Disease eIF2B mutant complexes
出版年份 2018 全文链接
标题
The small molecule ISRIB rescues the stability and activity of Vanishing White Matter Disease eIF2B mutant complexes
作者
关键词
-
出版物
eLife
Volume 7, Issue -, Pages -
出版商
eLife Sciences Organisation, Ltd.
发表日期
2018-03-01
DOI
10.7554/elife.32733
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Mutant eIF2B leads to impaired mitochondrial oxidative phosphorylation in vanishing white matter disease
- (2017) Gali Raini et al. JOURNAL OF NEUROCHEMISTRY
- Fail-safe control of translation initiation by dissociation of eIF2α phosphorylated ternary complexes
- (2017) Martin D Jennings et al. eLife
- Astrocytes are central in the pathomechanisms of vanishing white matter
- (2016) Stephanie Dooves et al. JOURNAL OF CLINICAL INVESTIGATION
- Crystal structure of eukaryotic translation initiation factor 2B
- (2016) Kazuhiro Kashiwagi et al. NATURE
- Paradoxical Sensitivity to an Integrated Stress Response Blocking Mutation in Vanishing White Matter Cells
- (2016) Yusuke Sekine et al. PLoS One
- Stoichiometry of the eIF2B complex is maintained by mutual stabilization of subunits
- (2015) N. C. Wortham et al. BIOCHEMICAL JOURNAL
- Architecture of the eIF2B regulatory subcomplex and its implications for the regulation of guanine nucleotide exchange on eIF2
- (2015) Bernhard Kuhle et al. NUCLEIC ACIDS RESEARCH
- Mutations in a translation initiation factor identify the target of a memory-enhancing compound
- (2015) Y. Sekine et al. SCIENCE
- Pharmacological dimerization and activation of the exchange factor eIF2B antagonizes the integrated stress response
- (2015) Carmela Sidrauski et al. eLife
- Insights into the Architecture of the eIF2Bα/β/δ Regulatory Subcomplex
- (2014) Andrew M. Bogorad et al. BIOCHEMISTRY
- Analysis of the subunit organization of the eIF2B complex reveals new insights into its structure and regulation
- (2014) Noel C. Wortham et al. FASEB JOURNAL
- eIF2B promotes eIF5 dissociation from eIF2*GDP to facilitate guanine nucleotide exchange for translation initiation
- (2013) M. D. Jennings et al. GENES & DEVELOPMENT
- A Yeast Purification System for Human Translation Initiation Factors eIF2 and eIF2Bε and Their Use in the Diagnosis of CACH/VWM Disease
- (2013) Rogerio A. de Almeida et al. PLoS One
- Pharmacological brake-release of mRNA translation enhances cognitive memory
- (2013) Carmela Sidrauski et al. eLife
- Improved methodology for the affinity isolation of human protein complexes expressed at near endogenous levels
- (2012) Michal Domanski et al. BIOTECHNIQUES
- The Mechanism of Eukaryotic Translation Initiation: New Insights and Challenges
- (2012) A. G. Hinnebusch et al. Cold Spring Harbor Perspectives in Biology
- A mouse model for eukaryotic translation initiation factor 2B-leucodystrophy reveals abnormal development of brain white matter
- (2011) Michal Geva et al. BRAIN
- Severity of vanishing white matter disease does not correlate with deficits in eIF2B activity or the integrity of eIF2B complexes
- (2011) Rui Liu et al. HUMAN MUTATION
- Phosphorylation of eIF2 Facilitates Ribosomal Bypass of an Inhibitory Upstream ORF to EnhanceCHOPTranslation
- (2011) Lakshmi Reddy Palam et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Regulation of the Unfolded Protein Response by eIF2Bδ Isoforms
- (2010) Leenus Martin et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Defective Glial Maturation in Vanishing White Matter Disease
- (2010) Marianna Bugiani et al. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
- Natural history of adult-onset eIF2B-related disorders: a multi-centric survey of 16 cases
- (2009) P. Labauge et al. BRAIN
- Eukaryotic Initiation Factor 2B (eIF2B) GEF Activity as a Diagnostic Tool for EIF2B-Related Disorders
- (2009) Laetitia Horzinski et al. PLoS One
- The UCSC Genome Browser Database: update 2009
- (2008) R. M. Kuhn et al. NUCLEIC ACIDS RESEARCH
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