Bacteriophage Endolysin: A Powerful Weapon to Control Bacterial Biofilms

Exebacase: A Novel Approach to the Treatment of Staphylococcal Infections

(2022) Matthew W. McCarthy   DRUGS IN R&D

Cloning, Characterization, and Antibacterial Properties of Endolysin LysE Against Planktonic Cells and Biofilms of Aeromonas hydrophila

(2022) Pallavi Baliga et al.   Probiotics and Antimicrobial Proteins

Preclinical Data on the Gardnerella -Specific Endolysin PM-477 Indicate Its Potential to Improve the Treatment of Bacterial Vaginosis through Enhanced Biofilm Removal and Avoidance of Resistance

(2022) Christine Landlinger et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Nanoantibiotics to fight multidrug resistant infections by Gram-positive bacteria: hope or reality?

(2022) Francesca Berini et al.   BIOTECHNOLOGY ADVANCES

Cloning and Characterization of a Thermostable Endolysin of Bacteriophage TP-84 as a Potential Disinfectant and Biofilm-Removing Biological Agent

(2022) Joanna Żebrowska et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The novel endolysin XZ.700 effectively treats MRSA biofilms in two biofilm models without showing toxicity on human bone cells in vitro

(2021) Jesse W. P Kuiper et al.   BIOFOULING

Comparison of Enterococcus faecalis Biofilm Removal Efficiency among Bacteriophage PBEF129, Its Endolysin, and Cefotaxime

(2021) Hyun Keun Oh et al.   Viruses-Basel

Synergistic effects of endolysin Lysqdvp001 and ε-poly-lysine in controlling Vibrio parahaemolyticus and its biofilms

(2021) Hou-Qi Ning et al.   INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY

Enhancing the Thermo-Stability and Anti-Bacterium Activity of Lysozyme by Immobilization on Chitosan Nanoparticles

(2020) Yanan Wang et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Antibiofilm Activity of a Broad-Range Recombinant Endolysin LysECD7: In Vitro and In Vivo Study

(2020) Mikhail V. Fursov et al.   Viruses-Basel

Impacts of food matrix on bacteriophage and endolysin antimicrobial efficacy and performance

(2019) Rachel Shannon et al.   CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION

The Antistaphylococcal Lysin, CF-301, Activates Key Host Factors in Human Blood To Potentiate Methicillin-Resistant Staphylococcus aureus Bacteriolysis

(2019) Chiara Indiani et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Ts2631 Endolysin from the Extremophilic Thermus scotoductus Bacteriophage vB_Tsc2631 as an Antimicrobial Agent against Gram-Negative Multidrug-Resistant Bacteria

(2019) Magdalena Plotka et al.   Viruses-Basel

Characterization of endolysins from bacteriophage LPST10 and evaluation of their potential for controlling Salmonella Typhimurium on lettuce

(2019) Aiping Liu et al.   LWT-FOOD SCIENCE AND TECHNOLOGY

In Vitro Study of Bacteriophage AB3 Endolysin LysAB3 Activity Against Acinetobacter baumannii Biofilm and Biofilm-Bound A. baumannii

(2018) Jie Zhang et al.   Clinical Laboratory

The Effect of Lysozyme on Reducing Biofilms by Staphylococcus aureus, Pseudomonas aeruginosa, and Gardnerella vaginalis: An In Vitro Examination

(2018) Mirsada Hukić et al.   Microbial Drug Resistance

A Chimeric LysK-Lysostaphin Fusion Enzyme Lysing Staphylococcus aureus Cells: a Study of Both Kinetics of Inactivation and Specifics of Interaction with Anionic Polymers

(2016) Lyubov Y. Filatova et al.   APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY

Antimicrobial Activity of Bacteriophage Endolysin Produced in Nicotiana benthamiana Plants

(2016) Natalia Kovalskaya et al.   JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY

LytM Fusion with SH3b-Like Domain Expands Its Activity to Physiological Conditions

(2016) Elzbieta Jagielska et al.   Microbial Drug Resistance

Novel Phage Lysin Capable of Killing the Multidrug-Resistant Gram-Negative Bacterium Acinetobacter baumannii in a Mouse Bacteremia Model

(2015) Rolf Lood et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Intravitreal Injection of the Chimeric Phage Endolysin Ply187 Protects Mice from Staphylococcus aureus Endophthalmitis

(2014) Pawan Kumar Singh et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Degradation of methicillin-resistantStaphylococcus aureusbiofilms using a chimeric lysin

(2014) Hang Yang et al.   BIOFOULING

A Thermostable Salmonella Phage Endolysin, Lys68, with Broad Bactericidal Properties against Gram-Negative Pathogens in Presence of Weak Acids

(2014) Hugo Oliveira et al.   PLoS One

Engineered Endolysin-Based "Artilysins" To Combat Multidrug-Resistant Gram-Negative Pathogens

(2014) Y. Briers et al.   mBio

Construction of a chimeric lysin Ply187N-V12C with extended lytic activity against staphylococci and streptococci

(2014) Qiuhua Dong et al.   Microbial Biotechnology

Novel Chimeric Lysin with High-Level Antimicrobial Activity against Methicillin-Resistant Staphylococcus aureus In Vitro andIn Vivo

(2013) Hang Yang et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Pseudomonas aeruginosa biofilm: Potential therapeutic targets

(2013) Garima Sharma et al.   BIOLOGICALS

Inhibiting biofilm formation by Klebsiella pneumoniae B5055 using an iron antagonizing molecule and a bacteriophage

(2013) Sanjay Chhibber et al.   BMC MICROBIOLOGY

Preparation and evaluation of lysozyme-loaded nanoparticles coated with poly-γ-glutamic acid and chitosan

(2013) Yong Liu et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Rapid degradation of Streptococcus pyogenes biofilms by PlyC, a bacteriophage-encoded endolysin

(2013) Yang Shen et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Existence of Separate Domains in Lysin PlyG for Recognizing Bacillus anthracis Spores and Vegetative Cells

(2012) Hang Yang et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Enhanced Staphylolytic Activity of the Staphylococcus aureus Bacteriophage vB_SauS-phiIPLA88 HydH5 Virion-Associated Peptidoglycan Hydrolase: Fusions, Deletions, and Synergy with LysH5

(2012) Lorena Rodríguez-Rubio et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Combined treatment ofPseudomonas aeruginosabiofilms with bacteriophages and chlorine

(2012) Yanyan Zhang et al.   BIOTECHNOLOGY AND BIOENGINEERING

Novel Chimerical Endolysins with Broad Antimicrobial Activity Against Methicillin-Resistant Staphylococcus aureus

(2012) Sofia Fernandes et al.   Microbial Drug Resistance

Characterization of endolysin from a Salmonella Typhimurium-infecting bacteriophage SPN1S

(2012) Jeong-A. Lim et al.   RESEARCH IN MICROBIOLOGY

Lytic activity of the virion-associated peptidoglycan hydrolase HydH5 of Staphylococcus aureus bacteriophage vB_SauS-phiIPLA88

(2011) Lorena Rodríguez et al.   BMC MICROBIOLOGY

Characterization of the staphylococcal bacteriophage lysin CHAPK

(2011) M. Fenton et al.   JOURNAL OF APPLIED MICROBIOLOGY

Structure-Based Modification of a Clostridium difficile-Targeting Endolysin Affects Activity and Host Range

(2011) M. J. Mayer et al.   JOURNAL OF BACTERIOLOGY

Domain shuffling and module engineering of Listeria phage endolysins for enhanced lytic activity and binding affinity

(2011) Mathias Schmelcher et al.   Microbial Biotechnology

Synergism between a Novel Chimeric Lysin and Oxacillin Protects against Infection by Methicillin-Resistant Staphylococcus aureus

(2010) A. Daniel et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

A Novel Chimeric Lysin Shows Superiority to Mupirocin for Skin Decolonization of Methicillin-Resistant and -SensitiveStaphylococcus aureusStrains

(2010) Mina Pastagia et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Rapid Multiplex Detection and Differentiation of Listeria Cells by Use of Fluorescent Phage Endolysin Cell Wall Binding Domains

(2010) M. Schmelcher et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Purified Recombinant Phage Lysin LySMP: An Extensive Spectrum of Lytic Activity for Swine Streptococci

(2009) Y. Wang et al.   CURRENT MICROBIOLOGY

Differentially conserved staphylococcal SH3b_5 cell wall binding domains confer increased staphylolytic and streptolytic activity to a streptococcal prophage endolysin domain

(2009) Stephen C. Becker et al.   GENE

Phage Lysin LysK Can Be Truncated to Its CHAP Domain and Retain Lytic Activity against Live Antibiotic-Resistant Staphylococci

(2008) M. Horgan et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY