Unraveling the mysteries of dendritic spine dynamics: Five key principles shaping memory and cognition

Spontaneous behaviour is structured by reinforcement without explicit reward

(2023) Jeffrey E. Markowitz et al.   NATURE

Generalized extinction of fear memory depends on co-allocation of synaptic plasticity in dendrites

(2023) Zhiwei Xu et al.   Nature Communications

A multi-omics view of neuronal subcellular protein synthesis

(2023) Chao Sun et al.   CURRENT OPINION IN NEUROBIOLOGY

Spike timing-dependent plasticity and memory

(2023) Dominique Debanne et al.   CURRENT OPINION IN NEUROBIOLOGY

Mechanical transmission at spine synapses: Short-term potentiation and working memory

(2023) Haruo Kasai et al.   CURRENT OPINION IN NEUROBIOLOGY

Dendritic spine dynamics in associative memory: A comprehensive review

(2023) Hongling Guo et al.   FASEB JOURNAL

NMDA receptor functions in health and disease: Old actor, new dimensions

(2023) Julien P. Dupuis et al.   NEURON

Distorted neurocomputation by a small number of extra-large spines in psychiatric disorders

(2023) Kisho Obi-Nagata et al.   Science Advances

Skewed distribution of spines is independent of presynaptic transmitter release and synaptic plasticity, and emerges early during adult neurogenesis

(2023) Nina Rößler et al.   Open Biology

The role of AMPAR lateral diffusion in memory

(2022) Daniel Choquet et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Nanoscale rules governing the organization of glutamate receptors in spine synapses are subunit specific

(2022) Martin Hruska et al.   Nature Communications

A midbrain-thalamus-cortex circuit reorganizes cortical dynamics to initiate movement

(2022) Hidehiko K. Inagaki et al.   CELL

Learning binds new inputs into functional synaptic clusters via spinogenesis

(2022) Nathan G. Hedrick et al.   NATURE NEUROSCIENCE

A behavioural correlate of the synaptic eligibility trace in the nucleus accumbens

(2022) Kenji Yamaguchi et al.   Scientific Reports

Randomly fluctuating neural connections may implement a consolidation mechanism that explains classic memory laws

(2022) Jaap M. J. Murre   Scientific Reports

Motor learning-induced new dendritic spines are preferentially involved in the learned task than existing spines

(2022) Qian Qiao et al.   Cell Reports

CaMKII binds both substrates and activators at the active site

(2022) Can Özden et al.   Cell Reports

Stability and dynamics of dendritic spines in macaque prefrontal cortex

(2022) Ming Chen et al.   National Science Review

High-resolution imaging and manipulation of endogenous AMPA receptor surface mobility during synaptic plasticity and learning

(2022) Angela M. Getz et al.   Science Advances

Presynaptic supervision of cortical spine dynamics in motor learning

(2022) Jaerin Sohn et al.   Science Advances

Molecular pathways of major depressive disorder converge on the synapse

(2022) Gabriel R. Fries et al.   MOLECULAR PSYCHIATRY

CaMKII: a central molecular organizer of synaptic plasticity, learning and memory

(2022) Ryohei Yasuda et al.   NATURE REVIEWS NEUROSCIENCE

Synaptic memory survives molecular turnover

(2022) Joel Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Multiple forms of working memory emerge from synapse–astrocyte interactions in a neuron–glia network model

(2022) Maurizio De Pittà et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Filopodia are a structural substrate for silent synapses in adult neocortex

(2022) Dimitra Vardalaki et al.   NATURE

Transsynaptic Signaling of Ephs in Synaptic Development, Plasticity, and Disease

(2022) Halley R. Washburn et al.   NEUROSCIENCE

Binary and analog variation of synapses between cortical pyramidal neurons

(2022) Sven Dorkenwald et al.   eLife

Non-ionotropic NMDA receptor signaling gates bidirectional structural plasticity of dendritic spines

(2021) Ivar S. Stein et al.   Cell Reports

Photoactivatable CaMKII induces synaptic plasticity in single synapses

(2021) Akihiro C. E. Shibata et al.   Nature Communications

The role of molecular diffusion within dendritic spines in synaptic function

(2021) Kazuki Obashi et al.   JOURNAL OF GENERAL PHYSIOLOGY

Ubiquitylation of lipopolysaccharide by RNF213 during bacterial infection

(2021) Elsje G. Otten et al.   NATURE

Attractor dynamics gate cortical information flow during decision-making

(2021) Arseny Finkelstein et al.   NATURE NEUROSCIENCE

Synaptic modifications in learning and memory – A dendritic spine story

(2021) Shaorong Ma et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

In vivo evidence of lower synaptic vesicle density in schizophrenia

(2021) Rajiv Radhakrishnan et al.   MOLECULAR PSYCHIATRY

A large-scale nanoscopy and biochemistry analysis of postsynaptic dendritic spines

(2021) Martin S. Helm et al.   NATURE NEUROSCIENCE

Spine dynamics in the brain, mental disorders and artificial neural networks

(2021) Haruo Kasai et al.   NATURE REVIEWS NEUROSCIENCE

Functional and molecular characterization of a non-human primate model of autism spectrum disorder shows similarity with the human disease

(2021) Satoshi Watanabe et al.   Nature Communications

AMPA receptor anchoring at CA1 synapses is determined by N-terminal domain and TARP γ8 interactions

(2021) Jake F. Watson et al.   Nature Communications

Optimal plasticity for memory maintenance during ongoing synaptic change

(2021) Dhruva Raman et al.   eLife

Stable but not rigid: Chronic in vivo STED nanoscopy reveals extensive remodeling of spines, indicating multiple drivers of plasticity

(2021) Heinz Steffens et al.   Science Advances

Computational roles of intrinsic synaptic dynamics

(2021) Genki Shimizu et al.   CURRENT OPINION IN NEUROBIOLOGY

Assessment of astrocytes as a mediator of memory and learning in rodents

(2021) Sonam Akther et al.   GLIA

Mechanical actions of dendritic-spine enlargement on presynaptic exocytosis

(2021) Hasan Ucar et al.   NATURE

A large majority of awake hippocampal sharp-wave ripples feature spatial trajectories with momentum

(2021) Emma L. Krause et al.   NEURON

AMPA receptor trafficking and LTP: Carboxy-termini, amino-termini and TARPs

(2021) Javier Díaz-Alonso et al.   NEUROPHARMACOLOGY

Voltage compartmentalization in dendritic spines in vivo

(2021) Victor Hugo Cornejo et al.   SCIENCE

Stepwise synaptic plasticity events drive the early phase of memory consolidation

(2021) Akihiro Goto et al.   SCIENCE

The critical balance between dopamine D2 receptor and RGS for the sensitive detection of a transient decay in dopamine signal

(2021) Hidetoshi Urakubo et al.   PLoS Computational Biology

Visualizing synaptic plasticity in vivo by large-scale imaging of endogenous AMPA receptors

(2021) Austin R Graves et al.   eLife

Synaptic memory requires CaMKII

(2021) Wucheng Tao et al.   eLife

Dual-component structural plasticity mediated by αCaMKII-autophosphorylation on basal dendrites of cortical layer 2/3 neurones

(2020) Gillian Seaton et al.   JOURNAL OF NEUROSCIENCE

Activity dependent and independent determinants of synaptic size diversity

(2020) Liran Hazan et al.   JOURNAL OF NEUROSCIENCE

AMPA receptor structure and auxiliary subunits

(2020) Aichurok Kamalova et al.   JOURNAL OF PHYSIOLOGY-LONDON

Conscious Processing and the Global Neuronal Workspace Hypothesis

(2020) George A. Mashour et al.   NEURON

SYNPLA, a method to identify synapses displaying plasticity after learning

(2020) Kim Dore et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Lamina-specific AMPA receptor dynamics following visual deprivation in vivo

(2020) Han L Tan et al.   eLife

Molecular Mechanisms of Non-ionotropic NMDA Receptor Signaling in Dendritic Spine Shrinkage

(2020) Ivar S. Stein et al.   JOURNAL OF NEUROSCIENCE

Dopamine D2 receptors in discrimination learning and spine enlargement

(2020) Yusuke Iino et al.   NATURE

The transition to compulsion in addiction

(2020) Christian Lüscher et al.   NATURE REVIEWS NEUROSCIENCE

Rapid 3D Enhanced Resolution Microscopy Reveals Diversity in Dendritic Spinule Dynamics, Regulation, and Function

(2020) Colleen R. Zaccard et al.   NEURON

AMPA receptor nanoscale dynamic organization and synaptic plasticities

(2020) Daniel Choquet et al.   CURRENT OPINION IN NEUROBIOLOGY

Dissociation of functional and structural plasticity of dendritic spines during NMDAR and mGluR-dependent long-term synaptic depression in wild-type and fragile X model mice

(2020) Aurore Thomazeau et al.   MOLECULAR PSYCHIATRY

Synapse and Active Zone Assembly in the Absence of Presynaptic Ca2+ Channels and Ca2+ Entry

(2020) Richard G. Held et al.   NEURON

Nanoscale co-organization and coactivation of AMPAR, NMDAR, and mGluR at excitatory synapses

(2020) Julia Goncalves et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A brain-wide atlas of synapses across the mouse lifespan

(2020) Mélissa Cizeron et al.   SCIENCE

Linking glutamate receptor movements and synapse function

(2020) Laurent Groc et al.   SCIENCE

Computational Characteristics of the Striatal Dopamine System Described by Reinforcement Learning With Fast Generalization

(2020) Yoshihisa Fujita et al.   Frontiers in Computational Neuroscience

Signaling models for dopamine-dependent temporal contiguity in striatal synaptic plasticity

(2020) Hidetoshi Urakubo et al.   PLoS Computational Biology

Achieving stable dynamics in neural circuits

(2020) Leo Kozachkov et al.   PLoS Computational Biology

Ultrastructural Imaging of Activity-Dependent Synaptic Membrane-Trafficking Events in Cultured Brain Slices

(2020) Cordelia Imig et al.   NEURON

A spike-timing-dependent plasticity rule for dendritic spines

(2020) Sabrina Tazerart et al.   Nature Communications

Astrocyte-mediated switch in spike timing-dependent plasticity during hippocampal development

(2020) Rafael Falcón-Moya et al.   Nature Communications

Endoplasmic reticulum visits highly active spines and prevents runaway potentiation of synapses

(2020) Alberto Perez-Alvarez et al.   Nature Communications

Cell-type-specific asynchronous modulation of PKA by dopamine in learning

(2020) Suk Joon Lee et al.   NATURE

Overexpression of schizophrenia susceptibility factor human complement C4A promotes excessive synaptic loss and behavioral changes in mice

(2020) Melis Yilmaz et al.   NATURE NEUROSCIENCE

Computational geometry analysis of dendritic spines by structured illumination microscopy

(2019) Yutaro Kashiwagi et al.   Nature Communications

Density of small dendritic spines and microtubule-associated-protein-2 immunoreactivity in the primary auditory cortex of subjects with schizophrenia

(2019) Brandon C. McKinney et al.   NEUROPSYCHOPHARMACOLOGY

Discrete attractor dynamics underlies persistent activity in the frontal cortex

(2019) Hidehiko K. Inagaki et al.   NATURE

Reciprocal Activation within a Kinase-Effector Complex Underlying Persistence of Structural LTP

(2019) Takeo Saneyoshi et al.   NEURON

Synaptic functions and their disruption in schizophrenia: From clinical evidence to synaptic optogenetics in an animal model

(2019) Kisho OBI-NAGATA et al.   PROCEEDINGS OF THE JAPAN ACADEMY SERIES B-PHYSICAL AND BIOLOGICAL SCIENCES

Precise Temporal Regulation of Molecular Diffusion within Dendritic Spines by Actin Polymers during Structural Plasticity

(2019) Kazuki Obashi et al.   Cell Reports

Sleep deprivation by exposure to novel objects increases synapse density and axon-spine interface in the hippocampal CA1 region of adolescent mice

(2019) Giovanna Maria Spano et al.   JOURNAL OF NEUROSCIENCE

The Stability of Glutamatergic Synapses Is Independent of Activity Level, but Predicted by Synapse Size

(2019) Dylan P. Quinn et al.   Frontiers in Cellular Neuroscience

Intrinsic Spine Dynamics Are Critical for Recurrent Network Learning in Models With and Without Autism Spectrum Disorder

(2019) James Humble et al.   Frontiers in Computational Neuroscience

Regulation of hippocampal dendritic spines following sleep deprivation

(2019) Barbara Gisabella et al.   JOURNAL OF COMPARATIVE NEUROLOGY

The next generation of approaches to investigate the link between synaptic plasticity and learning

(2019) Yann Humeau et al.   NATURE NEUROSCIENCE

Believing in dopamine

(2019) Samuel J. Gershman et al.   NATURE REVIEWS NEUROSCIENCE

Phase Separation-Mediated TARP/MAGUK Complex Condensation and AMPA Receptor Synaptic Transmission

(2019) Menglong Zeng et al.   NEURON

Target-wide Induction and Synapse Type-Specific Robustness of Presynaptic Homeostasis

(2019) Özgür Genç et al.   CURRENT BIOLOGY

An integrative framework for perceptual disturbances in psychosis

(2019) Guillermo Horga et al.   NATURE REVIEWS NEUROSCIENCE

Electrodiffusion Theory to Map the Voltage Distribution in Dendritic Spines at a Nanometer Scale

(2019) Jerome Cartailler et al.   NEURON

Bidirectional in vivo structural dendritic spine plasticity revealed by two-photon glutamate uncaging in the mouse neocortex

(2019) Jun Noguchi et al.   Scientific Reports

C. elegans neurons have functional dendritic spines

(2019) Andrea Cuentas-Condori et al.   eLife

Silent synapses dictate cocaine memory destabilization and reconsolidation

(2019) William J. Wright et al.   NATURE NEUROSCIENCE

Cortical Synaptic AMPA Receptor Plasticity during Motor Learning

(2019) Richard H. Roth et al.   NEURON

Cocaine-Induced Structural Plasticity in Input Regions to Distinct Cell Types in Nucleus Accumbens

(2018) Cindy Barrientos et al.   BIOLOGICAL PSYCHIATRY

Shifting patterns of polyribosome accumulation at synapses over the course of hippocampal long-term potentiation

(2018) Linnaea E. Ostroff et al.   HIPPOCAMPUS

Rapid nongenomic modulation by neurosteroids of dendritic spines in the hippocampus: Androgen, oestrogen and corticosteroid

(2018) G. Murakami et al.   JOURNAL OF NEUROENDOCRINOLOGY

Synaptic nanomodules underlie the organization and plasticity of spine synapses

(2018) Martin Hruska et al.   NATURE NEUROSCIENCE

PKCα integrates spatiotemporally distinct Ca2+ and autocrine BDNF signaling to facilitate synaptic plasticity

(2018) Lesley A Colgan et al.   NATURE NEUROSCIENCE

Dendritic structural plasticity and neuropsychiatric disease

(2018) Marc P. Forrest et al.   NATURE REVIEWS NEUROSCIENCE

Calcineurin knockout mice show a selective loss of small spines

(2018) Hitoshi Okazaki et al.   NEUROSCIENCE LETTERS

Synaptic Tenacity or Lack Thereof: Spontaneous Remodeling of Synapses

(2018) Noam E. Ziv et al.   TRENDS IN NEUROSCIENCES

Hotspots of dendritic spine turnover facilitate clustered spine addition and learning and memory

(2018) Adam C. Frank et al.   Nature Communications

The CaMKII/NMDA receptor complex controls hippocampal synaptic transmission by kinase-dependent and independent mechanisms

(2018) Salvatore Incontro et al.   Nature Communications

Chronic 2P-STED imaging reveals high turnover of dendritic spines in the hippocampus in vivo

(2018) Thomas Pfeiffer et al.   eLife

Inhibitory connectivity defines the realm of excitatory plasticity

(2018) Gianluigi Mongillo et al.   NATURE NEUROSCIENCE

Architecture of the Mouse Brain Synaptome

(2018) Fei Zhu et al.   NEURON

Pre-post synaptic alignment through neuroligin-1 tunes synaptic transmission efficiency

(2018) Kalina T Haas et al.   eLife

Competition for synaptic building blocks shapes synaptic plasticity

(2018) Jochen Triesch et al.   eLife

The shape of work to come

(2017) Emily Anthes   NATURE

Hippocampal LTP and contextual learning require surface diffusion of AMPA receptors

(2017) A. C. Penn et al.   NATURE

Synaptic weight set by Munc13-1 supramolecular assemblies

(2017) Hirokazu Sakamoto et al.   NATURE NEUROSCIENCE

REM sleep selectively prunes and maintains new synapses in development and learning

(2017) Wei Li et al.   NATURE NEUROSCIENCE

Synaptic Correlates of Working Memory Capacity

(2017) Yuanyuan Mi et al.   NEURON

Transcellular Nanoalignment of Synaptic Function

(2017) Thomas Biederer et al.   NEURON

Assembly of Excitatory Synapses in the Absence of Glutamatergic Neurotransmission

(2017) Richard Sando et al.   NEURON

Deprivation-Induced Homeostatic Spine Scaling In Vivo Is Localized to Dendritic Branches that Have Undergone Recent Spine Loss

(2017) Samuel J. Barnes et al.   NEURON

Memory Erasure Experiments Indicate a Critical Role of CaMKII in Memory Storage

(2017) Tom Rossetti et al.   NEURON

Synaptic Transmission Optimization Predicts Expression Loci of Long-Term Plasticity

(2017) Rui Ponte Costa et al.   NEURON

Imaging ERK and PKA Activation in Single Dendritic Spines during Structural Plasticity

(2017) Shen Tang et al.   NEURON

Formation and Maintenance of Functional Spines in the Absence of Presynaptic Glutamate Release

(2017) Albrecht Sigler et al.   NEURON

Ultrastructural evidence for synaptic scaling across the wake/sleep cycle

(2017) Luisa de Vivo et al.   SCIENCE

Structure-property relationships from universal signatures of plasticity in disordered solids

(2017) E. D. Cubuk et al.   SCIENCE

An Update on Memory Reconsolidation Updating

(2017) Jonathan L.C. Lee et al.   TRENDS IN COGNITIVE SCIENCES

Slow-wave sleep is controlled by a subset of nucleus accumbens core neurons in mice

(2017) Yo Oishi et al.   Nature Communications

Autism-like behaviours and enhanced memory formation and synaptic plasticity in Lrfn2/SALM1-deficient mice

(2017) Naoko Morimura et al.   Nature Communications

Mechanistic target of rapamycin is necessary for changes in dendritic spine morphology associated with long-term potentiation

(2017) Fredrick E. Henry et al.   Molecular Brain

Cooperative stochastic binding and unbinding explain synaptic size dynamics and statistics

(2017) Aseel Shomar et al.   PLoS Computational Biology

Synaptic transmission and plasticity require AMPA receptor anchoring via its N-terminal domain

(2017) Jake F Watson et al.   eLife

The AMPA receptor-associated protein Shisa7 regulates hippocampal synaptic function and contextual memory

(2017) Leanne J M Schmitz et al.   eLife

Long-Term Potentiation: From CaMKII to AMPA Receptor Trafficking

(2016) Bruce E. Herring et al.   Annual Review of Physiology

Stress and Cocaine Trigger Divergent and Cell Type–Specific Regulation of Synaptic Transmission at Single Spines in Nucleus Accumbens

(2016) Lena A. Khibnik et al.   BIOLOGICAL PSYCHIATRY

Castration alters the number and structure of dendritic spines in the male posterodorsal medial amygdala

(2016) Mariana Zancan et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Autocrine BDNF–TrkB signalling within a single dendritic spine

(2016) Stephen C. Harward et al.   NATURE

Rho GTPase complementation underlies BDNF-dependent homo- and heterosynaptic plasticity

(2016) Nathan G. Hedrick et al.   NATURE

Forward-genetics analysis of sleep in randomly mutagenized mice

(2016) Hiromasa Funato et al.   NATURE

Adult restoration of Shank3 expression rescues selective autistic-like phenotypes

(2016) Yuan Mei et al.   NATURE

A trans-synaptic nanocolumn aligns neurotransmitter release to receptors

(2016) Ai-Hui Tang et al.   NATURE

Computational principles of synaptic memory consolidation

(2016) Marcus K Benna et al.   NATURE NEUROSCIENCE

Opposing mechanisms mediate morphine- and cocaine-induced generation of silent synapses

(2016) Nicholas M Graziane et al.   NATURE NEUROSCIENCE

Dopamine reward prediction-error signalling: a two-component response

(2016) Wolfram Schultz   NATURE REVIEWS NEUROSCIENCE

Hippocampal GluA1 expression in Gria1 −/− mice only partially restores spatial memory performance deficits

(2016) Florian Freudenberg et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

The Diversity of Spine Synapses in Animals

(2016) Ronald S. Petralia et al.   NEUROMOLECULAR MEDICINE

Inhibitory Synapses Are Repeatedly Assembled and Removed at Persistent Sites In Vivo

(2016) Katherine L. Villa et al.   NEURON

Phosphoproteomics of the Dopamine Pathway Enables Discovery of Rap1 Activation as a Reward Signal In Vivo

(2016) Taku Nagai et al.   NEURON

CaMKII Phosphorylation of TARPγ-8 Is a Mediator of LTP and Learning and Memory

(2016) Joongkyu Park et al.   NEURON

Emergence of functional subnetworks in layer 2/3 cortex induced by sequential spikes in vivo

(2016) Taekeun Kim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Reassessment of long-term depression in cerebellar Purkinje cells in mice carrying mutated GluA2 C terminus

(2016) Kazuhiko Yamaguchi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

In vivo imaging identifies temporal signature of D1 and D2 medium spiny neurons in cocaine reward

(2016) Erin S. Calipari et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Extensive phosphorylation of AMPA receptors in neurons

(2016) Graham H. Diering et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Imprinting and recalling cortical ensembles

(2016) L. Carrillo-Reid et al.   SCIENCE

Homeostatic Plasticity Achieved by Incorporation of Random Fluctuations and Soft-Bounded Hebbian Plasticity in Excitatory Synapses

(2016) Takashi Matsubara et al.   Frontiers in Neural Circuits

Rule learning enhances structural plasticity of long-range axons in frontal cortex

(2016) Carolyn M. Johnson et al.   Nature Communications

Location-dependent synaptic plasticity rules by dendritic spine cooperativity

(2016) Jens P. Weber et al.   Nature Communications

Symmetric spike timing-dependent plasticity at CA3–CA3 synapses optimizes storage and recall in autoassociative networks

(2016) Rajiv K. Mishra et al.   Nature Communications

Abnormal intrinsic dynamics of dendritic spines in a fragile X syndrome mouse model in vivo

(2016) Akira Nagaoka et al.   Scientific Reports

State-dependent diffusion of actin-depolymerizing factor/cofilin underlies the enlargement and shrinkage of dendritic spines

(2016) Jun Noguchi et al.   Scientific Reports

Periodic F-actin structures shape the neck of dendritic spines

(2016) Julia Bär et al.   Scientific Reports

Loss of Microtubule-Associated Protein 2 Immunoreactivity Linked to Dendritic Spine Loss in Schizophrenia

(2015) Micah A. Shelton et al.   BIOLOGICAL PSYCHIATRY

Long-term potentiation and the role of N -methyl- d -aspartate receptors

(2015) Arturas Volianskis et al.   BRAIN RESEARCH

Reconstruction and Simulation of Neocortical Microcircuitry

(2015) Henry Markram et al.   CELL

Predicting the Dynamics of Network Connectivity in the Neocortex

(2015) Y. Loewenstein et al.   JOURNAL OF NEUROSCIENCE

Sensing Positive versus Negative Reward Signals through Adenylyl Cyclase-Coupled GPCRs in Direct and Indirect Pathway Striatal Medium Spiny Neurons

(2015) A. G. Nair et al.   JOURNAL OF NEUROSCIENCE

Non-Ionotropic NMDA Receptor Signaling Drives Activity-Induced Dendritic Spine Shrinkage

(2015) I. S. Stein et al.   JOURNAL OF NEUROSCIENCE

Phasic Dopamine Modifies Sensory-Driven Output of Striatal Neurons through Synaptic Plasticity

(2015) S. Wieland et al.   JOURNAL OF NEUROSCIENCE

Impermanence of dendritic spines in live adult CA1 hippocampus

(2015) Alessio Attardo et al.   NATURE

Labelling and optical erasure of synaptic memory traces in the motor cortex

(2015) Akiko Hayashi-Takagi et al.   NATURE

Branch-specific dendritic Ca2+ spikes cause persistent synaptic plasticity

(2015) Joseph Cichon et al.   NATURE

Genomic profiling of DNA methyltransferases reveals a role for DNMT3B in genic methylation

(2015) Tuncay Baubec et al.   NATURE

Visualization of NMDA receptor–dependent AMPA receptor synaptic plasticity in vivo

(2015) Yong Zhang et al.   NATURE NEUROSCIENCE

Rapid Dispersion of SynGAP from Synaptic Spines Triggers AMPA Receptor Insertion and Spine Enlargement during LTP

(2015) Yoichi Araki et al.   NEURON

Stoichiometry and Phosphoisotypes of Hippocampal AMPA-Type Glutamate Receptor Phosphorylation

(2015) Tomohisa Hosokawa et al.   NEURON

Lengthening of the Stargazin Cytoplasmic Tail Increases Synaptic Transmission by Promoting Interaction to Deeper Domains of PSD-95

(2015) Anne-Sophie Hafner et al.   NEURON

Sufficiency of Mesolimbic Dopamine Neuron Stimulation for the Progression to Addiction

(2015) Vincent Pascoli et al.   NEURON

Distinct Eligibility Traces for LTP and LTD in Cortical Synapses

(2015) Kaiwen He et al.   NEURON

Dendritic spine alterations in schizophrenia

(2015) Caitlin E. Moyer et al.   NEUROSCIENCE LETTERS

Dendritic spine dysgenesis in autism related disorders

(2015) Mary Phillips et al.   NEUROSCIENCE LETTERS

‘Activity-silent’ working memory in prefrontal cortex: a dynamic coding framework

(2015) Mark G. Stokes   TRENDS IN COGNITIVE SCIENCES

Two-photon fluorescence lifetime imaging of primed SNARE complexes in presynaptic terminals and β cells

(2015) Noriko Takahashi et al.   Nature Communications

Electrical behaviour of dendritic spines as revealed by voltage imaging

(2015) Marko A. Popovic et al.   Nature Communications

Heterosynaptic Structural Plasticity on Local Dendritic Segments of Hippocampal CA1 Neurons

(2015) Won Chan Oh et al.   Cell Reports

Network Plasticity as Bayesian Inference

(2015) David Kappel et al.   PLoS Computational Biology

Nanoconnectomic upper bound on the variability of synaptic plasticity

(2015) Thomas M Bartol et al.   eLife

Retroactive modulation of spike timing-dependent plasticity by dopamine

(2015) Zuzanna Brzosko et al.   eLife

Channelopathies and dendritic dysfunction in fragile X syndrome

(2014) Darrin H. Brager et al.   BRAIN RESEARCH BULLETIN

Autism-Associated Neuroligin-3 Mutations Commonly Impair Striatal Circuits to Boost Repetitive Behaviors

(2014) Patrick E. Rothwell et al.   CELL

Dopaminergic modulation of striatal networks in health and Parkinson's disease

(2014) D James Surmeier et al.   CURRENT OPINION IN NEUROBIOLOGY

Nanoscale segregation of actin nucleation and elongation factors determines dendritic spine protrusion

(2014) Anaël Chazeau et al.   EMBO JOURNAL

Long-Term Memory Stabilized by Noise-Induced Rehearsal

(2014) Y. Wei et al.   JOURNAL OF NEUROSCIENCE

Morphologic changes of dendritic spines of striatal neurons in the levodopa-induced dyskinesia model

(2014) Haruo Nishijima et al.   MOVEMENT DISORDERS

Engineering a memory with LTD and LTP

(2014) Sadegh Nabavi et al.   NATURE

Biological insights from 108 schizophrenia-associated genetic loci

(2014)   NATURE

Spine neck plasticity regulates compartmentalization of synapses

(2014) Jan Tønnesen et al.   NATURE NEUROSCIENCE

Structural and Molecular Remodeling of Dendritic Spine Substructures during Long-Term Potentiation

(2014) Miquel Bosch et al.   NEURON

Sleep and the Price of Plasticity: From Synaptic and Cellular Homeostasis to Memory Consolidation and Integration

(2014) Giulio Tononi et al.   NEURON

Direct Reactivation of a Coherent Neocortical Memory of Context

(2014) Kiriana K. Cowansage et al.   NEURON

Modeling the Dynamic Interaction of Hebbian and Homeostatic Plasticity

(2014) Taro Toyoizumi et al.   NEURON

Geniposide and its iridoid analogs exhibit antinociception by acting at the spinal GLP-1 receptors

(2014) Nian Gong et al.   NEUROPHARMACOLOGY

α-Actinin-2 Mediates Spine Morphology and Assembly of the Post-Synaptic Density in Hippocampal Neurons

(2014) Jennifer L. Hodges et al.   PLoS One

Activity-dependent dendritic spine neck changes are correlated with synaptic strength

(2014) R. Araya et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sleep promotes branch-specific formation of dendritic spines after learning

(2014) G. Yang et al.   SCIENCE

A critical time window for dopamine actions on the structural plasticity of dendritic spines

(2014) S. Yagishita et al.   SCIENCE

Dopaminergic basis of salience dysregulation in psychosis

(2014) Toby T. Winton-Brown et al.   TRENDS IN NEUROSCIENCES

Formation and maintenance of neuronal assemblies through synaptic plasticity

(2014) Ashok Litwin-Kumar et al.   Nature Communications

Enhanced synapse remodelling as a common phenotype in mouse models of autism

(2014) Masaaki Isshiki et al.   Nature Communications

Spatiotemporal dynamics of dendritic spines in the living brain

(2014) Chia-Chien Chen et al.   Frontiers in Neuroanatomy

Synaptic Size Dynamics as an Effectively Stochastic Process

(2014) Adiel Statman et al.   PLoS Computational Biology

A chemist and biologist talk to each other about caged neurotransmitters

(2013) Graham CR Ellis-Davies   Beilstein Journal of Organic Chemistry

Distribution of CaMKIIα expression in the brain in vivo, studied by CaMKIIα-GFP mice

(2013) Xinjun Wang et al.   BRAIN RESEARCH

Mechano-Gated Ion Channels in Sensory Systems

(2013) Patrick Delmas et al.   CELL

Local palmitoylation cycles define activity-regulated postsynaptic subdomains

(2013) Yuko Fukata et al.   JOURNAL OF CELL BIOLOGY

PTEN knockdown alters dendritic spine/protrusion morphology, not density

(2013) Michael E. Haws et al.   JOURNAL OF COMPARATIVE NEUROLOGY

LTP-Induced Long-Term Stabilization of Individual Nascent Dendritic Spines

(2013) T. C. Hill et al.   JOURNAL OF NEUROSCIENCE

Matching Dynamics of Presynaptic and Postsynaptic Scaffolds

(2013) A. Fisher-Lavie et al.   JOURNAL OF NEUROSCIENCE

Dendritic Spine Instability Leads to Progressive Neocortical Spine Loss in a Mouse Model of Huntington's Disease

(2013) R. P. Murmu et al.   JOURNAL OF NEUROSCIENCE

Dendritic Arborization and Spine Dynamics Are Abnormal in the Mouse Model of MECP2 Duplication Syndrome

(2013) M. Jiang et al.   JOURNAL OF NEUROSCIENCE

Super-Resolution Imaging Reveals That AMPA Receptors Inside Synapses Are Dynamically Organized in Nanodomains Regulated by PSD95

(2013) D. Nair et al.   JOURNAL OF NEUROSCIENCE

Epigenetic regulation of RAC1 induces synaptic remodeling in stress disorders and depression

(2013) Sam A Golden et al.   NATURE MEDICINE

An optimized fluorescent probe for visualizing glutamate neurotransmission

(2013) Jonathan S Marvin et al.   NATURE METHODS

Cocaine-induced structural plasticity in frontal cortex correlates with conditioned place preference

(2013) Francisco Javier Muñoz-Cuevas et al.   NATURE NEUROSCIENCE

GABA promotes the competitive selection of dendritic spines by controlling local Ca2+ signaling

(2013) Tatsuya Hayama et al.   NATURE NEUROSCIENCE

Circadian glucocorticoid oscillations promote learning-dependent synapse formation and maintenance

(2013) Conor Liston et al.   NATURE NEUROSCIENCE

LTP Requires a Unique Postsynaptic SNARE Fusion Machinery

(2013) Sandra Jurado et al.   NEURON

A Predictive Network Model of Cerebral Cortical Connectivity Based on a Distance Rule

(2013) Mária Ercsey-Ravasz et al.   NEURON

Synaptic Scaling and Homeostatic Plasticity in the Mouse Visual Cortex In Vivo

(2013) Tara Keck et al.   NEURON

Nanoscale Scaffolding Domains within the Postsynaptic Density Concentrate Synaptic AMPA Receptors

(2013) Harold D. MacGillavry et al.   NEURON

Two sides to long-term potentiation: a view towards reconciliation

(2013) Z. Padamsey et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Long-term depression triggers the selective elimination of weakly integrated synapses

(2013) J. S. Wiegert et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Distinct kinetics of synaptic structural plasticity, memory formation, and memory decay in massed and spaced learning

(2013) W. Aziz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Metabotropic NMDA receptor function is required for NMDA receptor-dependent long-term depression

(2013) S. Nabavi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A model-based prediction of the calcium responses in the striatal synaptic spines depending on the timing of cortical and dopaminergic inputs and post-synaptic spikes

(2013) Takashi Nakano et al.   Frontiers in Computational Neuroscience

Nonlinear Decoding and Asymmetric Representation of Neuronal Input Information by CaMKIIα and Calcineurin

(2013) Hajime Fujii et al.   Cell Reports

Gradual extinction prevents the return of fear: implications for the discovery of state

(2013) Samuel J. Gershman et al.   Frontiers in Behavioral Neuroscience

The CaMKII/NMDAR complex as a molecular memory

(2013) Magdalena Sanhueza et al.   Molecular Brain

CaV1 and CaV2 Channels Engage Distinct Modes of Ca2+ Signaling to Control CREB-Dependent Gene Expression

(2012) Damian G. Wheeler et al.   CELL

A Critical and Cell-Autonomous Role for MeCP2 in Synaptic Scaling Up

(2012) M. P. Blackman et al.   JOURNAL OF NEUROSCIENCE

Synaptic amplification by dendritic spines enhances input cooperativity

(2012) Mark T. Harnett et al.   NATURE

LTP requires a reserve pool of glutamate receptors independent of subunit type

(2012) Adam J. Granger et al.   NATURE

Repetitive motor learning induces coordinated formation of clustered dendritic spines in vivo

(2012) Min Fu et al.   NATURE

Improving FRET dynamic range with bright green and red fluorescent proteins

(2012) Amy J Lam et al.   NATURE METHODS

Mechanisms of CaMKII action in long-term potentiation

(2012) John Lisman et al.   NATURE REVIEWS NEUROSCIENCE

Stress, anxiety, and dendritic spines: What are the connections?

(2012) B. Leuner et al.   NEUROSCIENCE

Dendritic spine pathology in schizophrenia

(2012) J.R. Glausier et al.   NEUROSCIENCE

Distinct Initial SNARE Configurations Underlying the Diversity of Exocytosis

(2012) Haruo Kasai et al.   PHYSIOLOGICAL REVIEWS

Synapse-specific and size-dependent mechanisms of spine structural plasticity accompanying synaptic weakening

(2012) Won Chan Oh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Locally Synchronized Synaptic Inputs

(2012) N. Takahashi et al.   SCIENCE

Synaptic Dysfunction in Depression: Potential Therapeutic Targets

(2012) R. S. Duman et al.   SCIENCE

Modulation of Striatal Projection Systems by Dopamine

(2011) Charles R. Gerfen et al.   Annual Review of Neuroscience

Stability of presynaptic vesicle pools and changes in synapse morphology in the amygdala following fear learning in adult rats

(2011) Linnaea E. Ostroff et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Multiplicative Dynamics Underlie the Emergence of the Log-Normal Distribution of Spine Sizes in the Neocortex In Vivo

(2011) Y. Loewenstein et al.   JOURNAL OF NEUROSCIENCE

In vivotwo-photon uncaging of glutamate revealing the structure-function relationships of dendritic spines in the neocortex of adult mice

(2011) Jun Noguchi et al.   JOURNAL OF PHYSIOLOGY-LONDON

Reversal of cocaine-evoked synaptic potentiation resets drug-induced adaptive behaviour

(2011) Vincent Pascoli et al.   NATURE

Local, persistent activation of Rho GTPases during plasticity of single dendritic spines

(2011) Hideji Murakoshi et al.   NATURE

Shank3 mutant mice display autistic-like behaviours and striatal dysfunction

(2011) João Peça et al.   NATURE

Consolidation and Reconsolidation: Two Lives of Memories?

(2011) Sam McKenzie et al.   NEURON

Long-Range Neuronal Circuits Underlying the Interaction between Sensory and Motor Cortex

(2011) Tianyi Mao et al.   NEURON

Activity-Dependent Clustering of Functional Synaptic Inputs on Developing Hippocampal Dendrites

(2011) Thomas Kleindienst et al.   NEURON

The Dendritic Branch Is the Preferred Integrative Unit for Protein Synthesis-Dependent LTP

(2011) Arvind Govindarajan et al.   NEURON

Compartmentalized versus Global Synaptic Plasticity on Dendrites Controlled by Experience

(2011) Hiroshi Makino et al.   NEURON

Glucocorticoids are critical regulators of dendritic spine development and plasticity in vivo

(2011) C. Liston et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Homeostatic Synaptic Plasticity: Local and Global Mechanisms for Stabilizing Neuronal Function

(2011) G. Turrigiano   Cold Spring Harbor Perspectives in Biology

Filopodia initiation

(2011) Changsong Yang et al.   Cell Adhesion & Migration

Adenylyl cyclase-cyclicAMP signaling in mood disorders: Role of the crucial phosphorylating enzyme protein kinase A

(2011) Yogesh Dwivedi   Neuropsychiatric Disease and Treatment

SNARE Conformational Changes that Prepare Vesicles for Exocytosis

(2010) Noriko Takahashi et al.   Cell Metabolism

Learning rules and persistence of dendritic spines

(2010) Haruo Kasai et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Structural Plasticity Underlies Experience-Dependent Functional Plasticity of Cortical Circuits

(2010) L. Wilbrecht et al.   JOURNAL OF NEUROSCIENCE

Autonomous CaMKII Can Promote either Long-Term Potentiation or Long-Term Depression, Depending on the State of T305/T306 Phosphorylation

(2010) H. J. Pi et al.   JOURNAL OF NEUROSCIENCE

Two-photon uncaging of γ-aminobutyric acid in intact brain tissue

(2010) Masanori Matsuzaki et al.   Nature Chemical Biology

GABA inhibition modulates NMDA-R mediated spike timing dependent plasticity (STDP) in a biophysical model

(2010) Vassilis Cutsuridis   NEURAL NETWORKS

Single-Cell Optogenetic Excitation Drives Homeostatic Synaptic Depression

(2010) Carleton P. Goold et al.   NEURON

Myosin IIb Regulates Actin Dynamics during Synaptic Plasticity and Memory Formation

(2010) Christopher S. Rex et al.   NEURON

CaMKII Triggers the Diffusional Trapping of Surface AMPARs through Phosphorylation of Stargazin

(2010) Patricio Opazo et al.   NEURON

Single-Molecule Discrimination of Discrete Perisynaptic and Distributed Sites of Actin Filament Assembly within Dendritic Spines

(2010) Nicholas A. Frost et al.   NEURON

Neural Syntax: Cell Assemblies, Synapsembles, and Readers

(2010) György Buzsáki   NEURON

Olfactory Learning in Drosophila

(2010) Germain U. Busto et al.   PHYSIOLOGY

Dendritic spine instability and insensitivity to modulation by sensory experience in a mouse model of fragile X syndrome

(2010) Feng Pan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

AMPA receptors are exocytosed in stimulated spines and adjacent dendrites in a Ras-ERK-dependent manner during long-term potentiation

(2010) M. A. Patterson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Spike-Timing Theory of Working Memory

(2010) Botond Szatmáry et al.   PLoS Computational Biology

Fractionating spatial memory with glutamate receptor subunit-knockout mice: Figure 1

(2009) David M. Bannerman   BIOCHEMICAL SOCIETY TRANSACTIONS

Impaired Plasticity at Specific Subset of Striatal Synapses in the Ts65Dn Mouse Model of Down Syndrome

(2009) Massimiliano Di Filippo et al.   BIOLOGICAL PSYCHIATRY

Characterization of dendritic spines in theDrosophilacentral nervous system

(2009) Florian Leiss et al.   Developmental Neurobiology

Induction and expression of GluA1 (GluR-A)-independent LTP in the hippocampus

(2009) Carola Romberg et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

A Single Brief Burst Induces GluR1-dependent Associative Short-term Potentiation: A Potential Mechanism for Short-term Memory

(2009) Martha A. Erickson et al.   JOURNAL OF COGNITIVE NEUROSCIENCE

Membrane Potential Changes in Dendritic Spines during Action Potentials and Synaptic Input

(2009) L. M. Palmer et al.   JOURNAL OF NEUROSCIENCE

Enhanced long-term and impaired short-term spatial memory in GluA1 AMPA receptor subunit knockout mice: Evidence for a dual-process memory model

(2009) D. J. Sanderson et al.   LEARNING & MEMORY

Activation of CaMKII in single dendritic spines during long-term potentiation

(2009) Seok-Jin R. Lee et al.   NATURE

Rapid formation and selective stabilization of synapses for enduring motor memories

(2009) Tonghui Xu et al.   NATURE

Stably maintained dendritic spines are associated with lifelong memories

(2009) Guang Yang et al.   NATURE

Two-color, two-photon uncaging of glutamate and GABA

(2009) Srinivas Kantevari et al.   NATURE METHODS

Amyloid beta from axons and dendrites reduces local spine number and plasticity

(2009) Wei Wei et al.   NATURE NEUROSCIENCE

Experience-dependent structural synaptic plasticity in the mammalian brain

(2009) Anthony Holtmaat et al.   NATURE REVIEWS NEUROSCIENCE

A single standard for memory: the case for reconsolidation

(2009) Karim Nader et al.   NATURE REVIEWS NEUROSCIENCE

A Coordinated Local Translational Control Point at the Synapse Involving Relief from Silencing and MOV10 Degradation

(2009) Sourav Banerjee et al.   NEURON

Dynamic Microtubules Regulate Dendritic Spine Morphology and Synaptic Plasticity

(2009) Jacek Jaworski et al.   NEURON

Rapid Functional Maturation of Nascent Dendritic Spines

(2009) Karen Zito et al.   NEURON

Endocytic Trafficking and Recycling Maintain a Pool of Mobile Surface AMPA Receptors Required for Synaptic Potentiation

(2009) Enrica Maria Petrini et al.   NEURON

AMPA Receptor Incorporation into Synapses during LTP: The Role of Lateral Movement and Exocytosis

(2009) Hiroshi Makino et al.   NEURON

Rapid modulation of spine morphology by the 5-HT2A serotonin receptor through kalirin-7 signaling

(2009) K. A. Jones et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Behavioral abnormalities in synapsin II knockout mice implicate a causal factor in schizophrenia

(2009) Bailee A. Dyck et al.   SYNAPSE

Long-Term Relationships between Synaptic Tenacity, Synaptic Remodeling, and Network Activity

(2009) Amir Minerbi et al.   PLOS BIOLOGY

HIV-1 at 25

(2008) David D. Ho et al.   CELL

The Self-Tuning Neuron: Synaptic Scaling of Excitatory Synapses

(2008) Gina G. Turrigiano   CELL

Synaptic clustering by dendritic signalling mechanisms

(2008) Matthew E Larkum et al.   CURRENT OPINION IN NEUROBIOLOGY

Principles of Long-Term Dynamics of Dendritic Spines

(2008) N. Yasumatsu et al.   JOURNAL OF NEUROSCIENCE

Smaller Dendritic Spines, Weaker Synaptic Transmission, but Enhanced Spatial Learning in Mice Lacking Shank1

(2008) A. Y. Hung et al.   JOURNAL OF NEUROSCIENCE

NMDA Receptor Subunit NR2A Is Required for Rapidly Acquired Spatial Working Memory But Not Incremental Spatial Reference Memory

(2008) D. M. Bannerman et al.   JOURNAL OF NEUROSCIENCE

Dendritic Spine Loss and Synaptic Alterations in Alzheimer’s Disease

(2008) Marlen Knobloch et al.   MOLECULAR NEUROBIOLOGY

Massive restructuring of neuronal circuits during functional reorganization of adult visual cortex

(2008) Tara Keck et al.   NATURE NEUROSCIENCE

The stress hormone corticosterone conditions AMPAR surface trafficking and synaptic potentiation

(2008) Laurent Groc et al.   NATURE NEUROSCIENCE

Destabilization of the Postsynaptic Density by PSD-95 Serine 73 Phosphorylation Inhibits Spine Growth and Synaptic Plasticity

(2008) Pascal Steiner et al.   NEURON

The Subspine Organization of Actin Fibers Regulates the Structure and Plasticity of Dendritic Spines

(2008) Naoki Honkura et al.   NEURON

Rapid enhancement of two-step wiring plasticity by estrogen and NMDA receptor activity

(2008) D. P. Srivastava et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Surface Mobility of Postsynaptic AMPARs Tunes Synaptic Transmission

(2008) M. Heine et al.   SCIENCE

Synaptic Theory of Working Memory

(2008) G. Mongillo et al.   SCIENCE

The Spread of Ras Activity Triggered by Activation of a Single Dendritic Spine

(2008) C. D. Harvey et al.   SCIENCE

Protein Synthesis and Neurotrophin-Dependent Structural Plasticity of Single Dendritic Spines

(2008) J.-i. Tanaka et al.   SCIENCE

Dichotomous Dopaminergic Control of Striatal Synaptic Plasticity

(2008) W. Shen et al.   SCIENCE

Autism-like behavioral phenotypes in BTBR T+tf/J mice

(2007) H. G. McFarlane et al.   GENES BRAIN AND BEHAVIOR