标题
Multiple regulations of Keap1/Nrf2 system by dietary phytochemicals
作者
关键词
-
出版物
MOLECULAR NUTRITION & FOOD RESEARCH
Volume 60, Issue 8, Pages 1731-1755
出版商
Wiley
发表日期
2016-04-11
DOI
10.1002/mnfr.201501017
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Crosstalk between Nrf2 and Notch signaling
- (2015) Nobunao Wakabayashi et al. FREE RADICAL BIOLOGY AND MEDICINE
- Roles of Nrf2 in cell proliferation and differentiation
- (2015) Shohei Murakami et al. FREE RADICAL BIOLOGY AND MEDICINE
- Epigenetic regulation of Keap1-Nrf2 signaling
- (2015) Yue Guo et al. FREE RADICAL BIOLOGY AND MEDICINE
- Molecular basis of the Keap1–Nrf2 system
- (2015) Takafumi Suzuki et al. FREE RADICAL BIOLOGY AND MEDICINE
- Structural basis of Keap1 interactions with Nrf2
- (2015) Peter Canning et al. FREE RADICAL BIOLOGY AND MEDICINE
- Examining the neuroprotective effects of protocatechuic acid and chrysin on in vitro and in vivo models of Parkinson disease
- (2015) Zaijun Zhang et al. FREE RADICAL BIOLOGY AND MEDICINE
- The emerging role of redox-sensitive Nrf2–Keap1 pathway in diabetes
- (2015) Elango Bhakkiyalakshmi et al. PHARMACOLOGICAL RESEARCH
- Blocking of JB6 Cell Transformation by Tanshinone IIA: Epigenetic Reactivation of Nrf2 Antioxidative Stress Pathway
- (2014) Ling Wang et al. AAPS Journal
- Apigenin Reactivates Nrf2 Anti-oxidative Stress Signaling in Mouse Skin Epidermal JB6 P + Cells Through Epigenetics Modifications
- (2014) Ximena Paredes-Gonzalez et al. AAPS Journal
- Hypoxia-Responsive MicroRNA-101 Promotes Angiogenesis via Heme Oxygenase-1/Vascular Endothelial Growth Factor Axis by Targeting Cullin 3
- (2014) Ji-Hee Kim et al. ANTIOXIDANTS & REDOX SIGNALING
- Baicalein modulates Nrf2/Keap1 system in both Keap1-dependent and Keap1-independent mechanisms
- (2014) Si Qin et al. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
- The histone acetylranseferase hMOF acetylates Nrf2 and regulates anti-drug responses in human non-small cell lung cancer
- (2014) Zhiwei Chen et al. BRITISH JOURNAL OF PHARMACOLOGY
- Epigenetic DNA Methylation of Antioxidative Stress Regulator NRF2 in Human Prostate Cancer
- (2014) T. O. Khor et al. Cancer Prevention Research
- Requirement and Epigenetics Reprogramming of Nrf2 in Suppression of Tumor Promoter TPA-Induced Mouse Skin Cell Transformation by Sulforaphane
- (2014) Z.-Y. Su et al. Cancer Prevention Research
- Resveratrol inhibits estrogen-induced breast carcinogenesis through induction of NRF2-mediated protective pathways
- (2014) Bhupendra Singh et al. CARCINOGENESIS
- MicroRNA-200a controls Nrf2 activation by target Keap1 in hepatic stellate cell proliferation and fibrosis
- (2014) Jing-Jing Yang et al. CELLULAR SIGNALLING
- The polycomb group protein EZH2 inhibits lung cancer cell growth by repressing the transcription factor Nrf2
- (2014) Ziming Li et al. FEBS LETTERS
- Epigenetic modifications of Nrf2-mediated glutamate–cysteine ligase: implications for the development of diabetic retinopathy and the metabolic memory phenomenon associated with its continued progression
- (2014) Manish Mishra et al. FREE RADICAL BIOLOGY AND MEDICINE
- Epigenetic Modifications of Nrf2 by 3,3′-diindolylmethane In Vitro in TRAMP C1 Cell Line and In Vivo TRAMP Prostate Tumors
- (2013) Tien-Yuan Wu et al. AAPS Journal
- Sulforaphane enhances Nrf2 expression in prostate cancer TRAMP C1 cells through epigenetic regulation
- (2013) Chengyue Zhang et al. BIOCHEMICAL PHARMACOLOGY
- MicroRNA-93 regulates NRF2 expression and is associated with breast carcinogenesis
- (2013) B. Singh et al. CARCINOGENESIS
- Epigenetic Reactivation of Nrf2 in Murine Prostate Cancer TRAMP C1 Cells by Natural Phytochemicals Z-Ligustilide and Radix Angelica Sinensis via Promoter CpG Demethylation
- (2013) Zheng-Yuan Su et al. CHEMICAL RESEARCH IN TOXICOLOGY
- Histone deacetylase 6–mediated selective autophagy regulates COPD-associated cilia dysfunction
- (2013) Hilaire C. Lam et al. JOURNAL OF CLINICAL INVESTIGATION
- Neuroprotection by Curcumin in Ischemic Brain Injury Involves the Akt/Nrf2 Pathway
- (2013) Jingxian Wu et al. PLoS One
- Jun dimerization protein 2 is a critical component of the Nrf2/MafK complex regulating the response to ROS homeostasis
- (2013) S Tanigawa et al. Cell Death & Disease
- Activation of the transcription factor Nrf2 in macrophages, Caco-2 cells and intact human gut tissue by Maillard reaction products and coffee
- (2012) Tanja Sauer et al. AMINO ACIDS
- The let-7 microRNA enhances heme oxygenase-1 by suppressing Bach1 and attenuates oxidant injury in human hepatocytes
- (2012) Weihong Hou et al. Biochimica et Biophysica Acta-Gene Regulatory Mechanisms
- Allicin Ameliorates Cardiac Hypertrophy and Fibrosis through Enhancing of Nrf2 Antioxidant Signaling Pathways
- (2012) Xian-Hui Li et al. CARDIOVASCULAR DRUGS AND THERAPY
- Procyanidins from Wild Grape (Vitis amurensis) Seeds Regulate ARE-Mediated Enzyme Expression via Nrf2 Coupled with p38 and PI3K/Akt Pathway in HepG2 Cells
- (2012) Min-Ji Bak et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Apo-8′-lycopenal Induces Expression of HO-1 and NQO-1 via the ERK/p38-Nrf2-ARE Pathway in Human HepG2 Cells
- (2012) Chih-Min Yang et al. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
- The cytoprotective effect of butin against oxidative stress is mediated by the up-regulation of manganese superoxide dismutase expression through a PI3K/Akt/Nrf2-dependent pathway
- (2012) Rui Zhang et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Gene expression profiling and pathway network analysis of hepatic metabolic enzymes targeted by baicalein
- (2012) Si Qin et al. JOURNAL OF ETHNOPHARMACOLOGY
- Histone methylation: a dynamic mark in health, disease and inheritance
- (2012) Eric L. Greer et al. NATURE REVIEWS GENETICS
- Identification of novel NRF2-regulated genes by ChIP-Seq: influence on retinoid X receptor alpha
- (2012) B. N. Chorley et al. NUCLEIC ACIDS RESEARCH
- The nuclear cofactor RAC3/AIB1/SRC-3 enhances Nrf2 signaling by interacting with transactivation domains
- (2012) J-H Kim et al. ONCOGENE
- Epigenetic modifications by dietary phytochemicals: Implications for personalized nutrition
- (2012) Sharmila Shankar et al. PHARMACOLOGY & THERAPEUTICS
- Dietary phytochemicals and cancer prevention: Nrf2 signaling, epigenetics, and cell death mechanisms in blocking cancer initiation and progression
- (2012) Jong Hun Lee et al. PHARMACOLOGY & THERAPEUTICS
- PPAR and Oxidative Stress: Con() Catenating NRF2 and FOXO
- (2012) Simone Polvani et al. PPAR Research
- Genipin up-regulates heme oxygenase-1 via PI3-kinase-JNK1/2-Nrf2 signaling pathway to enhance the anti-inflammatory capacity in RAW264.7 macrophages
- (2011) Woo-Kwang Jeon et al. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
- The cytoprotective role of the Keap1–Nrf2 pathway
- (2011) Liam Baird et al. ARCHIVES OF TOXICOLOGY
- Strongylophorine-8, a pro-electrophilic compound from the marine sponge Petrosia (Strongylophora) corticata, provides neuroprotection through Nrf2/ARE pathway
- (2011) Shunsuke Sasaki et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
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- (2011) Won Yong Seo et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
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- (2011) Tin Oo Khor et al. BIOCHEMICAL PHARMACOLOGY
- Alginate oligosaccharide protects against endoplasmic reticulum- and mitochondrial-mediated apoptotic cell death and oxidative stress
- (2011) Solaleh Khoramian Tusi et al. BIOMATERIALS
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- (2011) Nanako Hamada et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Pharmacodynamics of dietary phytochemical indoles I3C and DIM: Induction of Nrf2-mediated phase II drug metabolizing and antioxidant genes and synergism with isothiocyanates
- (2011) Constance Lay-Lay Saw et al. BIOPHARMACEUTICS & DRUG DISPOSITION
- Nrf2-mediated induction of phase 2 detoxifying enzymes by glyceollins derived from soybean exposed to Aspergillus sojae
- (2011) Hyo Jung Kim et al. Biotechnology Journal
- Renal Cyst Formation in Fh1-Deficient Mice Is Independent of the Hif/Phd Pathway: Roles for Fumarate in KEAP1 Succination and Nrf2 Signaling
- (2011) Julie Adam et al. CANCER CELL
- Guggulsterone induces heme oxygenase-1 expression through activation of Nrf2 in human mammary epithelial cells: PTEN as a putative target
- (2011) I. Almazari et al. CARCINOGENESIS
- Nuclear factor p65 interacts with Keap1 to repress the Nrf2-ARE pathway
- (2011) Miao Yu et al. CELLULAR SIGNALLING
- Aberrations of EZH2 in Cancer
- (2011) A. Chase et al. CLINICAL CANCER RESEARCH
- Procyanidin B2 induces Nrf2 translocation and glutathione S-transferase P1 expression via ERKs and p38-MAPK pathways and protect human colonic cells against oxidative stress
- (2011) Ildefonso Rodríguez-Ramiro et al. EUROPEAN JOURNAL OF NUTRITION
- Neuroprotective and anti-inflammatory effects of mollugin via up-regulation of heme oxygenase-1 in mouse hippocampal and microglial cells
- (2011) Gil-Saeng Jeong et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- [6]-Gingerol attenuates β-amyloid-induced oxidative cell death via fortifying cellular antioxidant defense system
- (2011) Chan Lee et al. FOOD AND CHEMICAL TOXICOLOGY
- Protective mechanisms of anthocyanins from purple sweet potato against tert-butyl hydroperoxide-induced hepatotoxicity
- (2011) Yong Pil Hwang et al. FOOD AND CHEMICAL TOXICOLOGY
- Molecular cross-talk between the NRF2/KEAP1 signaling pathway, autophagy, and apoptosis
- (2011) Tomasz M. Stępkowski et al. FREE RADICAL BIOLOGY AND MEDICINE
- Heme oxygenase 1 is induced by miR-155 via reduced BACH1 translation in endothelial cells
- (2011) Kati H. Pulkkinen et al. FREE RADICAL BIOLOGY AND MEDICINE
- 3′,4′-Didemethylnobiletin induces phase II detoxification gene expression and modulates PI3K/Akt signaling in PC12 cells
- (2011) Jeng-Dian Su et al. FREE RADICAL BIOLOGY AND MEDICINE
- 4-Ketopinoresinol, a novel naturally occurring ARE activator, induces the Nrf2/HO-1 axis and protects against oxidative stress-induced cell injury via activation of PI3K/AKT signaling
- (2011) Huang-Hui Chen et al. FREE RADICAL BIOLOGY AND MEDICINE
- Signaling pathways activated by the phytochemical nordihydroguaiaretic acid contribute to a Keap1-independent regulation of Nrf2 stability: Role of glycogen synthase kinase-3
- (2011) Ana I. Rojo et al. FREE RADICAL BIOLOGY AND MEDICINE
- Schisandrin B elicits a glutathione antioxidant response and protects against apoptosis via the redox-sensitive ERK/Nrf2 pathway in AML12 hepatocytes
- (2011) Pou Kuan Leong et al. FREE RADICAL RESEARCH
- Schisandra chinensis α-iso-cubebenol induces heme oxygenase-1 expression through PI3K/Akt and Nrf2 signaling and has anti-inflammatory activity in Porphyromonas gingivalis lipopolysaccharide-stimulated macrophages
- (2011) Sun Young Park et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- Berberine induces heme oxygenase-1 up-regulation through phosphatidylinositol 3-kinase/AKT and NF-E2-related factor-2 signaling pathway in astrocytes
- (2011) Jia-Hong Chen et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- Effect of Diallyl Sulfide on in Vitro and in Vivo Nrf2-Mediated Pulmonic Antioxidant Enzyme Expression via Activation ERK/p38 Signaling Pathway
- (2011) Cheng-Ying Ho et al. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
- Fucoxanthin Enhances HO-1 and NQO1 Expression in Murine Hepatic BNL CL.2 Cells through Activation of the Nrf2/ARE System Partially by Its Pro-oxidant Activity
- (2011) Cheng-Ling Liu et al. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
- Dynamics of Nrf2 and Keap1 in ARE-MediatedNQO1Expression by Wasabi 6-(Methylsulfinyl)hexyl Isothiocyanate
- (2011) De-Xing Hou et al. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
- Hydroxytyrosol Induces Proliferation and Cytoprotection against Oxidative Injury in Vascular Endothelial Cells: Role of Nrf2 Activation and HO-1 Induction
- (2011) Houda Zrelli et al. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
- Pterostilbene Is More Potent than Resveratrol in Preventing Azoxymethane (AOM)-Induced Colon Tumorigenesis via Activation of the NF-E2-Related Factor 2 (Nrf2)-Mediated Antioxidant Signaling Pathway
- (2011) Yi-Siou Chiou et al. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
- Acetylation-Deacetylation of the Transcription Factor Nrf2 (Nuclear Factor Erythroid 2-related Factor 2) Regulates Its Transcriptional Activity and Nucleocytoplasmic Localization
- (2011) Yumiko Kawai et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- miR-200a Regulates Nrf2 Activation by TargetingKeap1mRNA in Breast Cancer Cells
- (2011) Gabriel Eades et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- PI3K and ERK/Nrf2 pathways are involved in oleanolic acid-induced heme oxygenase-1 expression in rat vascular smooth muscle cells
- (2011) Jian Feng et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Fisetin induces Nrf2-mediated HO-1 expression through PKC-δ and p38 in human umbilical vein endothelial cells
- (2011) Seung Eun Lee et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- ent-kaur-16-en-19-oic acid, isolated from the roots of Aralia continentalis, induces activation of Nrf2
- (2011) Ji Hyo Lyu et al. JOURNAL OF ETHNOPHARMACOLOGY
- Extract of Salvia miltiorrhiza (Danshen) induces Nrf2-mediated heme oxygenase-1 expression as a cytoprotective action in RAW 264.7 macrophages
- (2011) Seung Eun Lee et al. JOURNAL OF ETHNOPHARMACOLOGY
- Carnosic Acid Induces the NAD(P)H: Quinone Oxidoreductase 1 Expression in Rat Clone 9 Cells through the p38/Nuclear Factor Erythroid-2 Related Factor 2 Pathway
- (2011) Chia-Wen Tsai et al. JOURNAL OF NUTRITION
- Stimulation of GSH synthesis to prevent oxidative stress-induced apoptosis by hydroxytyrosol in human retinal pigment epithelial cells: activation of Nrf2 and JNK-p62/SQSTM1 pathways
- (2011) Xuan Zou et al. JOURNAL OF NUTRITIONAL BIOCHEMISTRY
- Stabilization of Nrf2 by tBHQ prevents LPS-induced apoptosis in differentiated PC12 cells
- (2011) Fariba Khodagholi et al. MOLECULAR AND CELLULAR BIOCHEMISTRY
- Coffees rich in chlorogenic acid or N-methylpyridinium induce chemopreventive phase II-enzymes via the Nrf2/ARE pathway in vitro and in vivo
- (2011) Ute Boettler et al. MOLECULAR NUTRITION & FOOD RESEARCH
- Potential roles of PI3K/Akt and Nrf2–Keap1 pathways in regulating hormesis of Z-ligustilide in PC12 cells against oxygen and glucose deprivation
- (2011) Hongyi Qi et al. NEUROPHARMACOLOGY
- Upregulation of Heme Oxygenase-1 by Acteoside Through ERK and PI3 K/Akt Pathway Confer Neuroprotection Against Beta-Amyloid-Induced Neurotoxicity
- (2011) Hong-Quan Wang et al. NEUROTOXICITY RESEARCH
- Stabilization of Nrf2 Protein by D3T Provides Protection against Ethanol-Induced Apoptosis in PC12 Cells
- (2011) Jian Dong et al. PLoS One
- Plant Polyphenol Curcumin Significantly Affects CYP1A2 and CYP2A6 Activity in Healthy, Male Chinese Volunteers
- (2010) Y. Chen et al. ANNALS OF PHARMACOTHERAPY
- Cancer Chemoprevention Mechanisms Mediated Through the Keap1–Nrf2 Pathway
- (2010) John D. Hayes et al. ANTIOXIDANTS & REDOX SIGNALING
- Piceatannol induces heme oxygenase-1 expression in human mammary epithelial cells through activation of ARE-driven Nrf2 signaling
- (2010) Hyun-Hee Lee et al. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
- Oxidized Phospholipids Regulate Expression of ATF4 and VEGF in Endothelial Cells via NRF2-Dependent Mechanism: Novel Point of Convergence Between Electrophilic and Unfolded Protein Stress Pathways
- (2010) Taras Afonyushkin et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Nrf-2 mediated heme oxygenase-1 expression, an antioxidant-independent mechanism, contributes to anti-atherogenesis and vascular protective effects of Ginkgo biloba extract
- (2010) Jia-Shiong Chen et al. ATHEROSCLEROSIS
- Bi-Functional Induction of the Quinone Reductase and Cytochrome P450 1A1 by Youngiasides via Nrf2-ARE and AhR-XRE Pathways
- (2010) Ji Ho Yun et al. BIOLOGICAL & PHARMACEUTICAL BULLETIN
- Ferulic Acid Protects Human Umbilical Vein Endothelial Cells from Radiation Induced Oxidative Stress by Phosphatidylinositol 3-Kinase and Extracellular Signal-Regulated Kinase Pathways
- (2010) Zeng-Chun Ma et al. BIOLOGICAL & PHARMACEUTICAL BULLETIN
- microRNA miR-144 modulates oxidative stress tolerance and associates with anemia severity in sickle cell disease
- (2010) C. Sangokoya et al. BLOOD
- Resveratrol Modulates Drug- and Carcinogen-Metabolizing Enzymes in a Healthy Volunteer Study
- (2010) H.-H. S. Chow et al. Cancer Prevention Research
- Effects of sappanchalcone on the cytoprotection and anti-inflammation via heme oxygenase-1 in human pulp and periodontal ligament cells
- (2010) Gil-Saeng Jeong et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Neurotrophic and Cytoprotective Action of Luteolin in PC12 Cells through ERK-Dependent Induction of Nrf2-Driven HO-1 Expression
- (2010) Chia-Wei Lin et al. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
- Hesperidin Upregulates Heme Oxygenase-1 To Attenuate Hydrogen Peroxide-Induced Cell Damage in Hepatic L02 Cells
- (2010) Ming-cang Chen et al. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
- Inhibition of neointimal formation by trans-resveratrol: Role of phosphatidyl inositol 3-kinase-dependent Nrf2 activation in heme oxygenase-1 induction
- (2010) Jung Woo Kim et al. MOLECULAR NUTRITION & FOOD RESEARCH
- Epigenetic modifications as therapeutic targets
- (2010) Theresa K Kelly et al. NATURE BIOTECHNOLOGY
- Regulation of Notch1 Signaling by Nrf2: Implications for Tissue Regeneration
- (2010) N. Wakabayashi et al. Science Signaling
- A formulated red ginseng extract rescues PC12 cells from PCB-induced oxidative cell death through Nrf2-mediated upregulation of heme oxygenase-1 and glutamate cysteine ligase
- (2010) So-Hyun Park et al. TOXICOLOGY
- Vegetarian diets: what do we know of their effects on common chronic diseases?
- (2009) Gary E Fraser AMERICAN JOURNAL OF CLINICAL NUTRITION
- Rottlerin induces heme oxygenase-1 (HO-1) up-regulation through reactive oxygen species (ROS) dependent and PKC δ-independent pathway in human colon cancer HT29 cells
- (2009) Eun Jung Park et al. BIOCHIMIE
- Dual Anti-oxidative Effects of Fraxetin Isolated from Fraxinus rhinchophylla
- (2009) Phuong Thien Thuong et al. BIOLOGICAL & PHARMACEUTICAL BULLETIN
- Epicatechin induces NF-κB, activator protein-1 (AP-1) and nuclear transcription factor erythroid 2p45-related factor-2 (Nrf2) via phosphatidylinositol-3-kinase/protein kinase B (PI3K/AKT) and extracellular regulated kinase (ERK) signalling in HepG2 cells
- (2009) Ana Belén Granado-Serrano et al. BRITISH JOURNAL OF NUTRITION
- Dietary Sulforaphane-Rich Broccoli Sprouts Reduce Colonization and Attenuate Gastritis in Helicobacter pylori-Infected Mice and Humans
- (2009) A. Yanaka et al. Cancer Prevention Research
- Protective mechanisms of 3-caffeoyl, 4-dihydrocaffeoyl quinic acid from Salicornia herbacea against tert-butyl hydroperoxide-induced oxidative damage
- (2009) Yong Pil Hwang et al. CHEMICO-BIOLOGICAL INTERACTIONS
- Targeting DNA Methylation
- (2009) J.-P. J. Issa et al. CLINICAL CANCER RESEARCH
- Cytoprotective effects of lindenenyl acetate isolated from Lindera strychnifolia on mouse hippocampal HT22 cells
- (2009) Bin Li et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Up-regulation of Nrf2-mediated heme oxygenase-1 expression by eckol, a phlorotannin compound, through activation of Erk and PI3K/Akt
- (2009) Ki Cheon Kim et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Catechol estrogens mediated activation of Nrf2 through covalent modification of its quinone metabolite to Keap1
- (2009) Daigo Sumi et al. JOURNAL OF TOXICOLOGICAL SCIENCES
- Acetylation of Nrf2 by p300/CBP Augments Promoter-Specific DNA Binding of Nrf2 during the Antioxidant Response
- (2009) Z. Sun et al. MOLECULAR AND CELLULAR BIOLOGY
- Direct Interaction between Nrf2 and p21Cip1/WAF1 Upregulates the Nrf2-Mediated Antioxidant Response
- (2009) Weimin Chen et al. MOLECULAR CELL
- Repeated oral administration modulates the pharmacokinetic behavior of the chemopreventive agent phenethyl isothiocyanate in rats
- (2009) Nattaya Konsue et al. MOLECULAR NUTRITION & FOOD RESEARCH
- A protective role of nuclear factor-erythroid 2-related factor-2 (Nrf2) in inflammatory disorders
- (2009) Jiyoung Kim et al. MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS
- Kaempferol Suppresses Cisplatin-Induced Apoptosis Via Inductions of Heme Oxygenase-1 and Glutamate-Cysteine Ligase Catalytic Subunit in HEI-OC1 cells
- (2009) Shang Shang Gao et al. PHARMACEUTICAL RESEARCH
- Cross-talk between Transcription Factors AhR and Nrf2: Lessons for Cancer Chemoprevention from Dioxin
- (2009) John D. Hayes et al. TOXICOLOGICAL SCIENCES
- Activation of the Nrf2/ARE pathway via S-alkylation of cysteine 151 in the chemopreventive agent-sensor Keap1 protein by falcarindiol, a conjugated diacetylene compound
- (2009) Tomokazu Ohnuma et al. TOXICOLOGY AND APPLIED PHARMACOLOGY
- Antiviral Activity of Nrf2 in a Murine Model of Respiratory Syncytial Virus Disease
- (2008) Hye-Youn Cho et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- (−)-Epigallocatechin gallate induces Nrf2-mediated antioxidant enzyme expression via activation of PI3K and ERK in human mammary epithelial cells
- (2008) Hye-Kyung Na et al. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
- NF-κB/p65 antagonizes Nrf2-ARE pathway by depriving CBP from Nrf2 and facilitating recruitment of HDAC3 to MafK
- (2008) Guang-Hui Liu et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Direct Inhibition of the Longevity-Promoting Factor SKN-1 by Insulin-like Signaling in C. elegans
- (2008) Jennifer M.A. Tullet et al. CELL
- Oral sulforaphane increases Phase II antioxidant enzymes in the human upper airway
- (2008) Marc A. Riedl et al. CLINICAL IMMUNOLOGY
- Oridonin Confers Protection against Arsenic-Induced Toxicity through Activation of the Nrf2-Mediated Defensive Response
- (2008) Yu Du et al. ENVIRONMENTAL HEALTH PERSPECTIVES
- The coffee diterpene kahweol induces heme oxygenase-1 via the PI3K and p38/Nrf2 pathway to protect human dopaminergic neurons from 6-hydroxydopamine-derived oxidative stress
- (2008) Yong Pil Hwang et al. FEBS LETTERS
- Protective mechanisms of Aralia continentalis extract against tert-butyl hydroperoxide-induced hepatotoxicity: In vivo and in vitro studies
- (2008) Yong Pil Hwang et al. FOOD AND CHEMICAL TOXICOLOGY
- Polymeric black tea polyphenols induce phase II enzymes via Nrf2 in mouse liver and lungs
- (2008) Rachana Patel et al. FREE RADICAL BIOLOGY AND MEDICINE
- γ-Tocopheryl quinone, notα-tocopheryl quinone, induces adaptive response through up-regulation of cellular glutathione and cysteine availability via activation of ATF4
- (2008) Yoko Ogawa et al. FREE RADICAL RESEARCH
- Protection of chlorophyllin against oxidative damage by inducing HO-1 and NQO1 expression mediated by PI3K/Akt and Nrf2
- (2008) Yanlin Zhang et al. FREE RADICAL RESEARCH
- Phosphorylation and Dephosphorylation of Tyrosine 141 Regulate Stability and Degradation of INrf2
- (2008) Abhinav K. Jain et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The protective effect of eupatilin on indomethacin-induced cell damage in cultured feline ileal smooth muscle cells: Involvement of HO-1 and ERK
- (2008) Hyun Ju Song et al. JOURNAL OF ETHNOPHARMACOLOGY
- The Antioxidant Defense System Keap1-Nrf2 Comprises a Multiple Sensing Mechanism for Responding to a Wide Range of Chemical Compounds
- (2008) M. Kobayashi et al. MOLECULAR AND CELLULAR BIOLOGY
- Nrf2-mediated induction of detoxifying enzymes by alantolactone present inInula helenium
- (2008) Ji Yeon Seo et al. PHYTOTHERAPY RESEARCH
- Cinnamaldehyde inhibits the tumor necrosis factor-α-induced expression of cell adhesion molecules in endothelial cells by suppressing NF-κB activation: Effects upon IκB and Nrf2
- (2008) Being-Chyuan Liao et al. TOXICOLOGY AND APPLIED PHARMACOLOGY
- Mechanism of phytoestrogen puerarin-mediated cytoprotection following oxidative injury: Estrogen receptor-dependent up-regulation of PI3K/Akt and HO-1
- (2008) Yong Pil Hwang et al. TOXICOLOGY AND APPLIED PHARMACOLOGY
- Resveratrol induces glutathione synthesis by activation of Nrf2 and protects against cigarette smoke-mediated oxidative stress in human lung epithelial cells
- (2007) Aruna Kode et al. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
- Anticarcinogenesis by dietary phytochemicals: Cytoprotection by Nrf2 in normal cells and cytotoxicity by modulation of transcription factors NF-κB and AP-1 in abnormal cancer cells
- (2007) Avanthika Gopalakrishnan et al. FOOD AND CHEMICAL TOXICOLOGY
- Carnosic acid, acatechol-typeelectrophilic compound, protects neurons bothin vitroandin vivothrough activation of the Keap1/Nrf2 pathway viaS-alkylation of targeted cysteines on Keap1
- (2007) Takumi Satoh et al. JOURNAL OF NEUROCHEMISTRY
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