Mitochondrial Metabolism Power SIRT2-Dependent Deficient Traffic Causing Alzheimer’s-Disease Related Pathology
出版年份 2016 全文链接
标题
Mitochondrial Metabolism Power SIRT2-Dependent Deficient Traffic Causing Alzheimer’s-Disease Related Pathology
作者
关键词
Alzheimer’s disease (AD), Sirtuin-2 (SIRT2), Autophagic-lysosomal pathway (ALP), Microtubules, Mitochondrial dynamics
出版物
MOLECULAR NEUROBIOLOGY
Volume 54, Issue 6, Pages 4021-4040
出版商
Springer Nature
发表日期
2016-06-17
DOI
10.1007/s12035-016-9951-x
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Amyloid-β-Induced Mitochondrial Dysfunction Impairs the Autophagic Lysosomal Pathway in a Tubulin Dependent Pathway
- (2018) Diana F.F. Silva et al. JOURNAL OF ALZHEIMERS DISEASE
- Abnormal Mitochondrial Dynamics in the Pathogenesis of Alzheimer's Disease
- (2018) Xiongwei Zhu et al. JOURNAL OF ALZHEIMERS DISEASE
- Inhibitors of Mitochondrial Fission as a Therapeutic Strategy for Diseases with Oxidative Stress and Mitochondrial Dysfunction
- (2018) P. Hemachandra Reddy JOURNAL OF ALZHEIMERS DISEASE
- Posttranslational modifications of α-tubulin in alzheimer disease
- (2015) Fan Zhang et al. Translational Neurodegeneration
- Biophysical Challenges to Axonal Transport: Motor-Cargo Deficiencies and Neurodegeneration
- (2014) Sandra E. Encalada et al. Annual Review of Biophysics
- Dual roles for autophagy: Degradation and secretion of Alzheimer's disease Aβ peptide
- (2014) Per Nilsson et al. BIOESSAYS
- Enhancing Astrocytic Lysosome Biogenesis Facilitates A Clearance and Attenuates Amyloid Plaque Pathogenesis
- (2014) Q. Xiao et al. JOURNAL OF NEUROSCIENCE
- The Upshot of LRRK2 Inhibition to Parkinson’s Disease Paradigm
- (2014) A. R. Esteves et al. MOLECULAR NEUROBIOLOGY
- Systemic regulation of mammalian ageing and longevity by brain sirtuins
- (2014) Akiko Satoh et al. Nature Communications
- The Alzheimer's disease mitochondrial cascade hypothesis: Progress and perspectives
- (2013) Russell H. Swerdlow et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Inhibition of ERK-DLP1 signaling and mitochondrial division alleviates mitochondrial dysfunction in Alzheimer's disease cybrid cell
- (2013) Xueqi Gan et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Prodromal Metabolic Phenotype in MCI Cybrids: Implications for Alzheimer’s Disease
- (2013) D. F. Silva et al. Current Alzheimer Research
- The tumor suppressor SirT2 regulates cell cycle progression and genome stability by modulating the mitotic deposition of H4K20 methylation
- (2013) L. Serrano et al. GENES & DEVELOPMENT
- Bioenergetic flux, mitochondrial mass and mitochondrial morphology dynamics in AD and MCI cybrid cell lines
- (2013) D. F. Silva et al. HUMAN MOLECULAR GENETICS
- Axonal transport deficits and neurodegenerative diseases
- (2013) Stéphanie Millecamps et al. NATURE REVIEWS NEUROSCIENCE
- Phosphorylation of tau protein at sites Ser396-404is one of the earliest events in Alzheimer's disease and Down syndrome
- (2013) S. Mondragón-Rodríguez et al. NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY
- Impaired autophagy and APP processing in Alzheimer's disease: The potential role of Beclin 1 interactome
- (2013) Antero Salminen et al. PROGRESS IN NEUROBIOLOGY
- Aβ Secretion and Plaque Formation Depend on Autophagy
- (2013) Per Nilsson et al. Cell Reports
- SIRT2 interferes with autophagy-mediated degradation of protein aggregates in neuronal cells under proteasome inhibition
- (2012) Jiyeong Gal et al. NEUROCHEMISTRY INTERNATIONAL
- Axonal transport and neurodegenerative disease: Can we see the elephant?
- (2012) Lawrence S.B. Goldstein PROGRESS IN NEUROBIOLOGY
- PINK1 autophosphorylation upon membrane potential dissipation is essential for Parkin recruitment to damaged mitochondria
- (2012) Kei Okatsu et al. Nature Communications
- Inhibition of Sirtuin 2 with Sulfobenzoic Acid Derivative AK1 is Non-Toxic and Potentially Neuroprotective in a Mouse Model of Frontotemporal Dementia
- (2012) Tara L. Spires-Jones et al. Frontiers in Pharmacology
- Abnormal accumulation of autophagic vesicles correlates with axonal and synaptic pathology in young Alzheimer’s mice hippocampus
- (2011) Raquel Sanchez-Varo et al. ACTA NEUROPATHOLOGICA
- Primary lysosomal dysfunction causes cargo-specific deficits of axonal transport leading to Alzheimer-like neuritic dystrophy
- (2011) SooYeon Lee et al. Autophagy
- Mitochondria: The Common Upstream Driver of Amyloid-β and Tau Pathology in Alzheimers Disease
- (2011) D. F.F. Silva et al. Current Alzheimer Research
- The mitochondrial intramembrane protease PARL cleaves human Pink1 to regulate Pink1 trafficking
- (2011) Cathrin Meissner et al. JOURNAL OF NEUROCHEMISTRY
- Protective Effects of Positive Lysosomal Modulation in Alzheimer's Disease Transgenic Mouse Models
- (2011) David Butler et al. PLoS One
- Emerging role of p62/sequestosome-1 in the pathogenesis of Alzheimer's disease
- (2011) Antero Salminen et al. PROGRESS IN NEUROBIOLOGY
- Acetylated microtubules are required for fusion of autophagosomes with lysosomes
- (2010) Rui Xie et al. BMC CELL BIOLOGY
- Reversal of autophagy dysfunction in the TgCRND8 mouse model of Alzheimer's disease ameliorates amyloid pathologies and memory deficits
- (2010) Dun-Sheng Yang et al. BRAIN
- Microtubule destruction induces tau liberation and its subsequent phosphorylation
- (2010) Tomohiro Miyasaka et al. FEBS LETTERS
- Role of TPPP/p25 on α-synuclein-mediated oligodendroglial degeneration and the protective effect of SIRT2 inhibition in a cellular model of multiple system atrophy☆
- (2010) Takafumi Hasegawa et al. NEUROCHEMISTRY INTERNATIONAL
- Regulation of Amyloid Precursor Protein Processing by the Beclin 1 Complex
- (2010) Philipp A. Jaeger et al. PLoS One
- SIRT2 inhibition achieves neuroprotection by decreasing sterol biosynthesis
- (2010) Ruth Luthi-Carter et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Mechanisms of tau-induced neurodegeneration
- (2009) Khalid Iqbal et al. ACTA NEUROPATHOLOGICA
- SIRT2-mediated protein deacetylation: An emerging key regulator in brain physiology and pathology
- (2009) Kai Harting et al. EUROPEAN JOURNAL OF CELL BIOLOGY
- Loss of PINK1 Function Promotes Mitophagy through Effects on Oxidative Stress and Mitochondrial Fission
- (2009) Ruben K. Dagda et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Impaired Balance of Mitochondrial Fission and Fusion in Alzheimer's Disease
- (2009) X. Wang et al. JOURNAL OF NEUROSCIENCE
- Dynamin-Like Protein 1 Reduction Underlies Mitochondrial Morphology and Distribution Abnormalities in Fibroblasts from Sporadic Alzheimer's Disease Patients
- (2008) Xinglong Wang et al. AMERICAN JOURNAL OF PATHOLOGY
- The regulation of SIRT2 function by cyclin-dependent kinases affects cell motility
- (2008) Ruwin Pandithage et al. JOURNAL OF CELL BIOLOGY
- The autophagy-related protein beclin 1 shows reduced expression in early Alzheimer disease and regulates amyloid β accumulation in mice
- (2008) Fiona Pickford et al. JOURNAL OF CLINICAL INVESTIGATION
- Nicotinamide Restores Cognition in Alzheimer's Disease Transgenic Mice via a Mechanism Involving Sirtuin Inhibition and Selective Reduction of Thr231-Phosphotau
- (2008) K. N. Green et al. JOURNAL OF NEUROSCIENCE
- Autophagy Induction and Autophagosome Clearance in Neurons: Relationship to Autophagic Pathology in Alzheimer's Disease
- (2008) B. Boland et al. JOURNAL OF NEUROSCIENCE
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now