Treatment-induced and pre-existing anti-PEG antibodies: Prevalence, clinical implications, and future perspectives
出版年份 2023 全文链接
标题
Treatment-induced and pre-existing anti-PEG antibodies: Prevalence, clinical implications, and future perspectives
作者
关键词
-
出版物
JOURNAL OF PHARMACEUTICAL SCIENCES
Volume -, Issue -, Pages -
出版商
Elsevier BV
发表日期
2023-11-05
DOI
10.1016/j.xphs.2023.11.001
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注意：仅列出部分参考文献，下载原文获取全部文献信息。- Investigation of anti-PEG antibody response to PEG-containing cosmetic products in mice
- (2023) Mohamed Ibrahim et al. JOURNAL OF CONTROLLED RELEASE
- Anti-PEG antibodies before and after a first dose of Comirnaty® (mRNA-LNP-based SARS-CoV-2 vaccine)
- (2023) Yaelle Bavli et al. JOURNAL OF CONTROLLED RELEASE
- Anti-PEG IgM production induced by PEGylated liposomes as a function of administration route
- (2023) Haruka Takata et al. JOURNAL OF CONTROLLED RELEASE
- Development of Pharmaceutical Nanomedicines: From the Bench to the Market
- (2022) Abdulrahman A. Halwani Pharmaceutics
- Branched PEG-modification: A new strategy for nanocarriers to evade of the accelerated blood clearance phenomenon and enhance anti-tumor efficacy
- (2022) Min Liu et al. BIOMATERIALS
- Pegfilgrastim-apgf (Nyvepria): Biosimilar USFDA approval for the treatment of chemotherapy-induced febrile neutropenia and current updates on clinical trials
- (2022) Faraat Ali et al. CURRENT DRUG TARGETS
- Polymer-drug conjugates: Design principles, emerging synthetic strategies and clinical overview
- (2022) Ankit Javia et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- A mouse model for studying the effect of blood anti-PEG IgMs levels on the in vivo fate of PEGylated liposomes
- (2022) Marwa M. El Sayed et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Anti-PEG Antibodies Boosted in Humans by SARS-CoV-2 Lipid Nanoparticle mRNA Vaccine
- (2022) Yi Ju et al. ACS Nano
- Monitoring Anti-PEG Antibodies Level upon Repeated Lipid Nanoparticle-Based COVID-19 Vaccine Administration
- (2022) Giuditta Guerrini et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- mRNA-1273 but not BNT162b2 induces antibodies against polyethylene glycol (PEG) contained in mRNA-based vaccine formulations
- (2022) Juan Manuel Carreño et al. VACCINE
- The mechanisms of anti-PEG immune response are different in the spleen and the lymph nodes
- (2022) Philippe Grenier et al. JOURNAL OF CONTROLLED RELEASE
- Clinical manifestations and impact on daily life of allergy to polyethylene glycol (PEG) in ten patients
- (2021) Maria A. Bruusgaard‐Mouritsen et al. CLINICAL AND EXPERIMENTAL ALLERGY
- Reports of Anaphylaxis After Receipt of mRNA COVID-19 Vaccines in the US—December 14, 2020-January 18, 2021
- (2021) Tom T. Shimabukuro et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Replacement of L-amino acid peptides with D-amino acid peptides mitigates anti-PEG antibody generation against polymer-peptide conjugates in mice
- (2021) Meilyn Sylvestre et al. JOURNAL OF CONTROLLED RELEASE
- Incorporating Gangliosides into PEGylated Cationic Liposomes that Complexed DNA Attenuates Anti-PEG Antibody Production but Not Anti-DNA Antibody Production in Mice
- (2021) Milad Reda Qelliny et al. MOLECULAR PHARMACEUTICS
- Initial report of decreased SARS-CoV-2 viral load after inoculation with the BNT162b2 vaccine
- (2021) Matan Levine-Tiefenbrun et al. NATURE MEDICINE
- Polyethylene Glycol Immunogenicity: Theoretical, Clinical, and Practical Aspects of Anti-Polyethylene Glycol Antibodies
- (2021) Bing-Mae Chen et al. ACS Nano
- Pegcetacoplan: First Approval
- (2021) Sheridan M. Hoy DRUGS
- Anti-PEG IgM production and accelerated blood clearance phenomenon after the administration of PEGylated exosomes in mice
- (2021) Sherif E. Emam et al. JOURNAL OF CONTROLLED RELEASE
- Impact of Antibodies Against Polyethylene Glycol on the Pharmacokinetics of PEGylated Asparaginase in Children with Acute Lymphoblastic Leukaemia: A Population Pharmacokinetic Approach
- (2021) Christian Siebel et al. EUROPEAN JOURNAL OF DRUG METABOLISM AND PHARMACOKINETICS
- Anti-PEG antibodies compromise the integrity of PEGylated lipid-based nanoparticles via complement
- (2021) Mariona Estapé Senti et al. JOURNAL OF CONTROLLED RELEASE
- Accelerated blood clearance and hypersensitivity by PEGylated liposomes containing TLR agonists
- (2021) Camilla Stavnsbjerg et al. JOURNAL OF CONTROLLED RELEASE
- The role and impact of polyethylene glycol on anaphylactic reactions to COVID-19 nano-vaccines
- (2021) P. Bigini et al. Nature Nanotechnology
- The Use of Lactose as an Alternative Coating for Nanoparticles
- (2020) Jamie L. Betker et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Antibodies against polyethylene glycol in human blood: A literature review
- (2020) Lu Hong et al. JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS
- Anti-PEG antibodies: Properties, formation, testing and role in adverse immune reactions to PEGylated nano-biopharmaceuticals
- (2020) Gergely Tibor Kozma et al. ADVANCED DRUG DELIVERY REVIEWS
- Pegfilgrastim (PEG-G-CSF) induces anti-PEG IgM in a dose dependent manner and causes the accelerated blood clearance (ABC) phenomenon upon repeated administration in mice
- (2020) Nehal E. Elsadek et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- Blood retention and antigenicity of polycarboxybetaine-modified liposomes
- (2020) Takaaki Ryujin et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Impact of Pre-Existing or Induced Anti-PEG IgM on the Pharmacokinetics of Peginterferon Alfa-2a (Pegasys) in Mice
- (2020) Nehal E. Elsadek et al. MOLECULAR PHARMACEUTICS
- Food additive emulsifiers: a review of their role in foods, legislation and classifications, presence in food supply, dietary exposure, and safety assessment
- (2020) Selina Cox et al. NUTRITION REVIEWS
- Drug Development through Modification of Small Molecular Drugs with Monodisperse Poly(ethylene glycol)s
- (2020) Tingjuan Wu et al. ORGANIC PROCESS RESEARCH & DEVELOPMENT
- Pegfilgrastim (PEG-G-CSF) Induces Anti-polyethylene Glycol (PEG) IgM via a T Cell-Dependent Mechanism
- (2020) Nehal E. Elsadek et al. BIOLOGICAL & PHARMACEUTICAL BULLETIN
- PEG shedding-rate-dependent blood clearance of PEGylated lipid nanoparticles in mice: Faster PEG shedding attenuates anti-PEG IgM production
- (2020) Takuya Suzuki et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Pre-existing antibodies against polyethylene glycol reduce asparaginase activities on first administration of pegylated E. coli asparaginase in children with acute lymphocytic leukemia
- (2020) Alaeddin Khalil et al. HAEMATOLOGICA
- Architectural Modification of Conformal PEG‐Bottlebrush Coatings Minimizes Anti‐PEG Antigenicity While Preserving Stealth Properties
- (2019) Daniel Y. Joh et al. Advanced Healthcare Materials
- Comparing the Real-World Effectiveness of Competing Colonoscopy Preparations
- (2019) Phillip Gu et al. AMERICAN JOURNAL OF GASTROENTEROLOGY
- Lipid-Based DNA Therapeutics – Hallmarks of Non-Viral Gene Delivery
- (2019) Jonas Buck et al. ACS Nano
- B Cell Responses: Cell Interaction Dynamics and Decisions
- (2019) Jason G. Cyster et al. CELL
- Perioperative haemostasis with full‐length, PEGylated, recombinant factor VIII with extended half‐life (rurioctocog alfa pegol) in patients with haemophilia A: Final results of a multicentre, single‐arm phase III trial
- (2019) Ralph Gruppo et al. HAEMOPHILIA
- Doxebo (doxorubicin-free Doxil-like liposomes) is safe to use as a pre-treatment to prevent infusion reactions to PEGylated nanodrugs
- (2019) Yaelle Bavli et al. JOURNAL OF CONTROLLED RELEASE
- FDA Approval Summary: Calaspargase Pegol-mknl For Treatment of Acute Lymphoblastic Leukemia in Children and Young Adults
- (2019) Ruo-Jing Li et al. CLINICAL CANCER RESEARCH
- Overcoming anti-PEG antibody mediated accelerated blood clearance of PEGylated liposomes by pre-infusion with high molecular weight free PEG
- (2019) Morgan D. McSweeney et al. JOURNAL OF CONTROLLED RELEASE
- A generic method for the detection of polyethylene glycol specific IgG and IgM antibodies in human serum
- (2019) Christopher Ehlinger et al. JOURNAL OF IMMUNOLOGICAL METHODS
- Safety and efficacy of BAY 94-9027, an extended-half-life factor VIII, during surgery in patients with severe hemophilia A: Results of the PROTECT VIII clinical trial
- (2019) Elena Santagostino et al. THROMBOSIS RESEARCH
- The Onpattro story and the clinical translation of nanomedicines containing nucleic acid-based drugs
- (2019) Akin Akinc et al. Nature Nanotechnology
- Aptamer chemistry
- (2018) Pascal Röthlisberger et al. ADVANCED DRUG DELIVERY REVIEWS
- Pegvaliase: First Global Approval
- (2018) Anthony Markham BIODRUGS
- A hydroxyl PEG version of PEGylated liposomes and its impact on anti-PEG IgM induction and on the accelerated clearance of PEGylated liposomes
- (2018) Taro Shimizu et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- Understanding the Role of Anti-PEG Antibodies in the Complement Activation by Doxil in Vitro
- (2018) Barry Neun et al. MOLECULES
- Pre-existing anti-polyethylene glycol antibody reduces the therapeutic efficacy and pharmacokinetics of PEGylated liposomes
- (2018) Yuan-Chin Hsieh et al. Theranostics
- Anti-polyethylene glycol antibodies alter the protein corona deposited on nanoparticles and the physiological pathways regulating their fate in vivo
- (2018) Philippe Grenier et al. JOURNAL OF CONTROLLED RELEASE
- POxylation as an alternative stealth coating for biomedical applications
- (2017) Herdis Bludau et al. EUROPEAN POLYMER JOURNAL
- Ganglioside inserted into PEGylated liposome attenuates anti-PEG immunity
- (2017) Yu Mima et al. JOURNAL OF CONTROLLED RELEASE
- Molecular Design, Expression and Evaluation of PASylated Human Recombinant Erythropoietin with Enhanced Functional Properties
- (2017) Mohammad Hossein Hedayati et al. PROTEIN JOURNAL
- Cross-Reactivity of Select PEG-Binding Antibodies to Other Polymers Containing a C-C-O Backbone
- (2017) Justin McCallen et al. ACS Biomaterials-Science & Engineering
- Cross-Reactivity of Select PEG-Binding Antibodies to Other Polymers Containing a C-C-O Backbone
- (2017) Justin McCallen et al. ACS Biomaterials Science & Engineering
- Drug delivery: Brushing off antigenicity
- (2017) Kang Choon Lee et al. Nature Biomedical Engineering
- Pre-existing Antibody: Biotherapeutic Modality-Based Review
- (2016) Boris Gorovits et al. AAPS Journal
- Analysis of Pre-existing IgG and IgM Antibodies against Polyethylene Glycol (PEG) in the General Population
- (2016) Qi Yang et al. ANALYTICAL CHEMISTRY
- Measurement of Pre-Existing IgG and IgM Antibodies against Polyethylene Glycol in Healthy Individuals
- (2016) Bing-Mae Chen et al. ANALYTICAL CHEMISTRY
- Immediate-type hypersensitivity to polyethylene glycols: a review
- (2016) E. Wenande et al. CLINICAL AND EXPERIMENTAL ALLERGY
- Polyethylene glycol (PEG): a versatile polymer for pharmaceutical applications
- (2016) Anisha A. D’souza et al. Expert Opinion on Drug Delivery
- The safety and efficacy of Onivyde (irinotecan liposome injection) for the treatment of metastatic pancreatic cancer following gemcitabine-based therapy
- (2016) Frank C. Passero et al. Expert Review of Anticancer Therapy
- Pre-existing anti-PEG antibodies are associated with severe immediate allergic reactions to pegnivacogin, a PEGylated aptamer
- (2016) Thomas J. Povsic et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Pre-existing anti–polyethylene glycol antibody linked to first-exposure allergic reactions to pegnivacogin, a PEGylated RNA aptamer
- (2016) Nancy J. Ganson et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Anti-PEG antibodies in the clinic: Current issues and beyond PEGylation
- (2016) Peng Zhang et al. JOURNAL OF CONTROLLED RELEASE
- The Mystery of Antibodies Against Polyethylene Glycol (PEG) - What do we Know?
- (2016) Christian Lubich et al. PHARMACEUTICAL RESEARCH
- Understanding the immunogenicity and antigenicity of nanomaterials: Past, present and future
- (2016) Anna N. Ilinskaya et al. TOXICOLOGY AND APPLIED PHARMACOLOGY
- A brush-polymer/exendin-4 conjugate reduces blood glucose levels for up to five days and eliminates poly(ethylene glycol) antigenicity
- (2016) Yizhi Qi et al. Nature Biomedical Engineering
- Tuning PEGylation of mixed micelles to overcome intracellular and systemic siRNA delivery barriers
- (2015) Martina Miteva et al. BIOMATERIALS
- Structure, function, self-assembly, and applications of bottlebrush copolymers
- (2015) Rafael Verduzco et al. CHEMICAL SOCIETY REVIEWS
- New FDA-Approved Disease-Modifying Therapies for Multiple Sclerosis
- (2015) Clayton English et al. CLINICAL THERAPEUTICS
- What is the future of PEGylated therapies?
- (2015) Magdalena Swierczewska et al. EXPERT OPINION ON EMERGING DRUGS
- Properties and functions of lactosylceramide from mouse neutrophils
- (2015) K. Iwabuchi et al. GLYCOBIOLOGY
- Anti-PEG IgM and complement system are required for the association of second doses of PEGylated liposomes with splenic marginal zone B cells
- (2015) Taro Shimizu et al. IMMUNOBIOLOGY
- Anti-PEG IgM Is a Major Contributor to the Accelerated Blood Clearance of Polyethylene Glycol-Conjugated Protein
- (2015) Yu Mima et al. MOLECULAR PHARMACEUTICS
- Zwitterionic gel encapsulation promotes protein stability, enhances pharmacokinetics, and reduces immunogenicity
- (2015) Peng Zhang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Anti-PEG immunity: emergence, characteristics, and unaddressed questions
- (2015) Qi Yang et al. Wiley Interdisciplinary Reviews-Nanomedicine and Nanobiotechnology
- Influence of phospholipid types and animal models on the accelerated blood clearance phenomenon of PEGylated liposomes upon repeated injection
- (2014) Huan Xu et al. DRUG DELIVERY
- Potential induction of anti-PEG antibodies and complement activation toward PEGylated therapeutics
- (2014) Johan J.F. Verhoef et al. DRUG DISCOVERY TODAY
- Activation of TLR9 by incorporated pDNA within PEG-coated lipoplex enhances anti-PEG IgM production
- (2014) Y Hashimoto et al. GENE THERAPY
- Influence of dose and animal species on accelerated blood clearance of PEGylated liposomal doxorubicin
- (2014) Takuya Suzuki et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- B cell-intrinsic toll-like receptor 7 is responsible for the enhanced anti-PEG IgM production following injection of siRNA-containing PEGylated lipoplex in mice
- (2014) Yosuke Hashimoto et al. JOURNAL OF CONTROLLED RELEASE
- Complement activation-related pseudoallergy: A stress reaction in blood triggered by nanomedicines and biologicals
- (2014) Janos Szebeni MOLECULAR IMMUNOLOGY
- Induced and pre-existing anti-polyethylene glycol antibody in a trial of every 3-week dosing of pegloticase for refractory gout, including in organ transplant recipients
- (2014) Michael S Hershfield et al. ARTHRITIS RESEARCH & THERAPY
- Anti-polyethyleneglycol Antibody Response to PEGylated Substances
- (2013) Tatsuhiro Ishida et al. BIOLOGICAL & PHARMACEUTICAL BULLETIN
- R&D Intensity and the New Product Development Portfolio
- (2013) Raul O. Chao et al. IEEE TRANSACTIONS ON ENGINEERING MANAGEMENT
- Use of polyglycerol (PG), instead of polyethylene glycol (PEG), prevents induction of the accelerated blood clearance phenomenon against long-circulating liposomes upon repeated administration
- (2013) Amr S. Abu Lila et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- The accelerated blood clearance (ABC) phenomenon: Clinical challenge and approaches to manage
- (2013) Amr S. Abu Lila et al. JOURNAL OF CONTROLLED RELEASE
- Application of Polyglycerol Coating to Plasmid DNA Lipoplex for the Evasion of the Accelerated Blood Clearance Phenomenon in Nucleic Acid Delivery
- (2013) Amr S. Abu Lila et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- PASylation: a biological alternative to PEGylation for extending the plasma half-life of pharmaceutically active proteins
- (2013) M. Schlapschy et al. PROTEIN ENGINEERING DESIGN & SELECTION
- Sylatron: A Pegylated Interferon for Use in Melanoma
- (2012) Jai N Patel et al. ANNALS OF PHARMACOTHERAPY
- Role of the Methoxy Group in Immune Responses to mPEG-Protein Conjugates
- (2012) Merry R. Sherman et al. BIOCONJUGATE CHEMISTRY
- Intravenous Administration of Polyethylene Glycol-Coated (PEGylated) Proteins and PEGylated Adenovirus Elicits an Anti-PEG Immunoglobulin M Response
- (2012) Taro Shimizu et al. BIOLOGICAL & PHARMACEUTICAL BULLETIN
- Influence of architecture of high molecular weight linear and branched polyglycerols on their biocompatibility and biodistribution
- (2012) Muhammad Imran ul-haq et al. BIOMATERIALS
- A frustrating problem: Accelerated blood clearance of PEGylated solid lipid nanoparticles following subcutaneous injection in rats
- (2012) Yongxue Zhao et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- Antibodies against polyethylene glycol in healthy subjects and in patients treated with PEG-conjugated agents
- (2012) Ricardo P Garay et al. Expert Opinion on Drug Delivery
- Size-dependent induction of accelerated blood clearance phenomenon by repeated injections of polymeric micelles
- (2012) Hiroyuki Koide et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Accelerated blood clearance of PEGylated liposomes containing doxorubicin upon repeated administration to dogs
- (2012) Takuya Suzuki et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Abrogation of the accelerated blood clearance phenomenon by SOXL regimen: Promise for clinical application
- (2012) Ai Nagao et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Prevention of infusion reactions to PEGylated liposomal doxorubicin via tachyphylaxis induction by placebo vesicles: A porcine model
- (2012) János Szebeni et al. JOURNAL OF CONTROLLED RELEASE
- Hydrophobic blocks of PEG-conjugates play a significant role in the accelerated blood clearance (ABC) phenomenon
- (2012) Kouichi Shiraishi et al. JOURNAL OF CONTROLLED RELEASE
- Accelerated Blood Clearance of Pegylated Liposomal Topotecan: Influence of Polyethylene Glycol Grafting Density and Animal Species
- (2012) Chunlei Li et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Conjugates of Superoxide Dismutase 1 with Amphiphilic Poly(2-oxazoline) Block Copolymers for Enhanced Brain Delivery: Synthesis, Characterization and Evaluation in Vitro and in Vivo
- (2012) Jing Tong et al. MOLECULAR PHARMACEUTICS
- Immune responses of therapeutic lipid nanoparticles
- (2012) Weihsu Claire Chen et al. Nanotechnology Reviews
- Activation of complement by therapeutic liposomes and other lipid excipient-based therapeutic products: Prediction and prevention
- (2011) Janos Szebeni et al. ADVANCED DRUG DELIVERY REVIEWS
- Polyoxazoline: Chemistry, Properties, and Applications in Drug Delivery
- (2011) Tacey X. Viegas et al. BIOCONJUGATE CHEMISTRY
- Effects of a novel pH-sensitive liposome with cleavable esterase-catalyzed and pH-responsive double smart mPEG lipid derivative on ABC phenomenon
- (2011) Daquan Chen et al. International Journal of Nanomedicine
- Anti-PEG IgM production by siRNA encapsulated in a PEGylated lipid nanocarrier is dependent on the sequence of the siRNA
- (2011) Tatsuaki Tagami et al. JOURNAL OF CONTROLLED RELEASE
- Differences in colloidal structure of PEGylated nanomaterials dictate the likelihood of accelerated blood clearance
- (2011) Lisa M. Kaminskas et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Liposome-induced complement activation and related cardiopulmonary distress in pigs: factors promoting reactogenicity of Doxil and AmBisome
- (2011) János Szebeni et al. Nanomedicine-Nanotechnology Biology and Medicine
- Cancer theranostics: the rise of targeted magnetic nanoparticles
- (2011) Adam J. Cole et al. TRENDS IN BIOTECHNOLOGY
- A double antigen bridging immunogenicity ELISA for the detection of antibodies to polyethylene glycol polymers
- (2011) Yijuan Liu et al. JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS
- Poly(ethylene glycol) in Drug Delivery: Pros and Cons as Well as Potential Alternatives
- (2010) Katrin Knop et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Tumor-Selective Delivery of Macromolecular Drugs via the EPR Effect: Background and Future Prospects
- (2010) Hiroshi Maeda BIOCONJUGATE CHEMISTRY
- Effects of cleavable PEG-cholesterol derivatives on the accelerated blood clearance of PEGylated liposomes
- (2010) Huan Xu et al. BIOMATERIALS
- PEGylation of therapeutic proteins
- (2010) Simona JevsÌevar et al. Biotechnology Journal
- Design of next-generation protein therapeutics
- (2010) Justin Caravella et al. CURRENT OPINION IN CHEMICAL BIOLOGY
- 307 HIGH PREVALENCE OF PRE-EXISTING ANTIBODIES AGAINST POLYETHYLENE GLYCOL (PEG) IN HEPATITIS C (HCV) PATIENTS WHICH IS NOT ASSOCIATED WITH IMPAIRED RESPONSE TO PEG-INTERFERON
- (2010) H. Tillmann et al. JOURNAL OF HEPATOLOGY
- Pegloticase
- (2010) Naomi Schlesinger et al. NATURE REVIEWS DRUG DISCOVERY
- Ultralow-Fouling, Functionalizable, and Hydrolyzable Zwitterionic Materials and Their Derivatives for Biological Applications
- (2009) Shaoyi Jiang et al. ADVANCED MATERIALS
- CpG motifs in pDNA-sequences increase anti-PEG IgM production induced by PEG-coated pDNA-lipoplexes
- (2009) Tatsuaki Tagami et al. JOURNAL OF CONTROLLED RELEASE
- Decoration of T-independent antigen with ligands for CD22 and Siglec-G can suppress immunity and induce B cell tolerance in vivo
- (2009) Bao Hoa Duong et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Effect of Molecular Weight, Temperature, and Additives on the Moisture Sorption Properties of Polyethylene Glycol
- (2009) Jared A. Baird et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Dynamics of Membrane Trafficking Downstream of B and T Cell Receptor Engagement: Impact on Immune Synapses
- (2009) Maria-Isabel Yuseff et al. TRAFFIC
- The Impact of PEGylation on Biological Therapies
- (2008) Francesco M Veronese et al. BIODRUGS
- Particle size-dependent triggering of accelerated blood clearance phenomenon
- (2008) Hiroyuki Koide et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Solid microemulsion preconcentrate (NanOsorb) of artemether for effective treatment of malaria
- (2008) Medha Joshi et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- PEGylation of Nanocarrier Drug Delivery Systems: State of the Art
- (2008) Melissa D. Howard et al. Journal of Biomedical Nanotechnology
- Esterase-catalyzed dePEGylation of pH-sensitive vesicles modified with cleavable PEG-lipid derivatives
- (2008) H XU et al. JOURNAL OF CONTROLLED RELEASE
- Molecular Simulation Studies of Protein Interactions with Zwitterionic Phosphorylcholine Self-Assembled Monolayers in the Presence of Water
- (2008) Yi He et al. LANGMUIR
- Certolizumab pegol
- (2008) Gil Y. Melmed et al. NATURE REVIEWS DRUG DISCOVERY
- Formulation of Neulasta® (pegfilgrastim)
- (2007) Deirdre Murphy Piedmonte et al. ADVANCED DRUG DELIVERY REVIEWS
- The effect of PEG coating on in vitro cytotoxicity and in vivo disposition of topotecan loaded liposomes in rats
- (2007) S DADASHZADEH et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Accelerated blood clearance (ABC) phenomenon upon repeated injection of PEGylated liposomes
- (2007) Tatsuhiro Ishida et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- The contribution of phagocytic activity of liver macrophages to the accelerated blood clearance (ABC) phenomenon of PEGylated liposomes in rats
- (2007) Tatsuhiro Ishida et al. JOURNAL OF CONTROLLED RELEASE
- Protein therapeutics: a summary and pharmacological classification
- (2007) Benjamin Leader et al. NATURE REVIEWS DRUG DISCOVERY
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