Induced and pre-existing anti-polyethylene glycol antibody in a trial of every 3-week dosing of pegloticase for refractory gout, including in organ transplant recipients

The Immunogenicity of Polyethylene Glycol: Facts and Fiction

(2013) Huub Schellekens et al.   PHARMACEUTICAL RESEARCH

Independent and conjoint associations of gout and hyperuricaemia with total and cardiovascular mortality

(2013) A.G. Stack et al.   QJM-AN INTERNATIONAL JOURNAL OF MEDICINE

PEGylated drugs in rheumatology--why develop them and do they work?

(2013) T. McDonnell et al.   RHEUMATOLOGY

Long-term safety of pegloticase in chronic gout refractory to conventional treatment

(2012) Michael A Becker et al.   ANNALS OF THE RHEUMATIC DISEASES

Role of the Methoxy Group in Immune Responses to mPEG-Protein Conjugates

(2012) Merry R. Sherman et al.   BIOCONJUGATE CHEMISTRY

Treating gout with pegloticase, a PEGylated urate oxidase, provides insight into the importance of uric acid as an antioxidant in vivo

(2010) M. S. Hershfield et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Quality of Life and Disability in Patients with Treatment-Failure Gout

(2009) M. A. BECKER et al.   JOURNAL OF RHEUMATOLOGY

A critical reappraisal of allopurinol dosing, safety, and efficacy for hyperuricemia in gout

(2009) Jeannie Chao et al.   Current Rheumatology Reports

Long-term Cardiovascular Mortality Among Middle-aged Men With Gout

(2008) Eswar Krishnan   ARCHIVES OF INTERNAL MEDICINE

Reduction of plasma urate levels following treatment with multiple doses of pegloticase (polyethylene glycol-conjugated uricase) in patients with treatment-failure gout: Results of a phase II randomized study

(2008) John S. Sundy et al.   ARTHRITIS AND RHEUMATISM

Serum uric acid is an independent predictor for all major forms of cardiovascular death in 28,613 elderly women: A prospective 21-year follow-up study

(2008) Alexander M. Strasak et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Population Pharmacokinetic and Pharmacodynamic Analysis of Pegloticase in Subjects With Hyperuricemia and Treatment-Failure Gout

(2008) Corinne Seng Yue et al.   JOURNAL OF CLINICAL PHARMACOLOGY

Serum Uric Acid and Risk of Cardiovascular Mortality: A Prospective Long-Term Study of 83 683 Austrian Men

(2007) A. Strasak et al.   CLINICAL CHEMISTRY