Dietary supplementation with L-leucine reduces nitric oxide synthesis by endothelial cells of rats

Detrimental effects of branched-chain amino acids in glucose tolerance can be attributed to valine induced glucotoxicity in skeletal muscle

(2022) Christopher A. Bishop et al.   Nutrition & Diabetes

l-Arginine increases AMPK phosphorylation and the oxidation of energy substrates in hepatocytes, skeletal muscle cells, and adipocytes

(2022) Wenjuan S. Jobgen et al.   AMINO ACIDS

Role of branched-chain amino acid metabolism in the pathogenesis of obesity and type 2 diabetes-related metabolic disturbances BCAA metabolism in type 2 diabetes

(2022) Froukje Vanweert et al.   Nutrition & Diabetes

l-Arginine supplementation regulates energy-substrate metabolism in skeletal muscle and adipose tissue of diet-induced obese rats

(2022) Wenjuan S Jobgen et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

BCAA Supplementation in Mice with Diet-Induced Obesity Alters the Metabolome Without Impairing Glucose Homeostasis

(2021) Jennifer Lee et al.   ENDOCRINOLOGY

Effects of branched-chain amino acids on glucose metabolism in obese, prediabetic men and women: a randomized, crossover study

(2019) Shih-Lung Woo et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Effects of dietary leucine on antioxidant activity and expression of antioxidant and mitochondrial‐related genes in longissimus dorsi muscle and liver of piglets

(2019) Xiaoling Chen et al.   ANIMAL SCIENCE JOURNAL

Oral administration of α-ketoglutarate enhances nitric oxide synthesis by endothelial cells and whole-body insulin sensitivity in diet-induced obese rats

(2019) Carmen D Tekwe et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

BCAA catabolism in brown fat controls energy homeostasis through SLC25A44

(2019) Takeshi Yoneshiro et al.   NATURE

Branched-chain amino acids in health and disease: metabolism, alterations in blood plasma, and as supplements

(2018) Milan Holeček   Nutrition & Metabolism

Does l-leucine supplementation cause any effect on glucose homeostasis in rodent models of glucose intolerance? A systematic review

(2018) Henver S. Brunetta et al.   AMINO ACIDS

High concentration of branched-chain amino acids promotes oxidative stress, inflammation and migration of human peripheral blood mononuclear cells via mTORC1 activation

(2017) Olha Zhenyukh et al.   FREE RADICAL BIOLOGY AND MEDICINE

Catabolic Defect of Branched-Chain Amino Acids Promotes Heart FailureCLINICAL PERSPECTIVE

(2016) Haipeng Sun et al.   CIRCULATION

Safety and Tolerability of Leucine Supplementation in Elderly Men

(2016) Rajavel Elango et al.   JOURNAL OF NUTRITION

Glycine Regulates Protein Turnover by Activating Protein Kinase B/Mammalian Target of Rapamycin and by Inhibiting MuRF1 and Atrogin-1 Gene Expression in C2C12 Myoblasts

(2016) KaiJi Sun et al.   JOURNAL OF NUTRITION

Leucine supplementation at the onset of high-fat feeding does not prevent weight gain or improve glycemic regulation in male Sprague-Dawley rats

(2016) Jamie I. Baum et al.   JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY

l-Leucine and NO-mediated cardiovascular function

(2015) Ying Yang et al.   AMINO ACIDS

Branched-chain amino acids in metabolic signalling and insulin resistance

(2014) Christopher J. Lynch et al.   Nature Reviews Endocrinology

Protein and glucose metabolic responses to hyperinsulinemia, hyperglycemia, and hyperaminoacidemia in obese men

(2014) Stéphanie Chevalier et al.   Obesity

l-Leucine Supplementation Worsens the Adiposity of Already Obese Rats by Promoting a Hypothalamic Pattern of Gene Expression that Favors Fat Accumulation

(2014) Thais Zampieri et al.   Nutrients

The link between vascular deterioration and branched chain amino acids in a population with high glycated haemoglobin: the SABPA study

(2013) C. M. Mels et al.   AMINO ACIDS

Oral administration of interferon tau enhances oxidation of energy substrates and reduces adiposity in Zucker diabetic fatty rats

(2013) Carmen D. Tekwe et al.   BIOFACTORS

Dietary leucine improves whole-body insulin sensitivity independent of body fat in diet-induced obese Sprague–Dawley rats

(2013) Lindsay K. Eller et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Leucine supplementation modulates fuel substrates utilization and glucose metabolism in previously obese mice

(2013) Elke Binder et al.   Obesity

Leucine Supplementation Protects from Insulin Resistance by Regulating Adiposity Levels

(2013) Elke Binder et al.   PLoS One

Insulin resistance and the metabolism of branched-chain amino acids in humans

(2011) María M. Adeva et al.   AMINO ACIDS

Nitric oxide and vascular insulin resistance

(2009) Guoyao Wu et al.   BIOFACTORS

A Branched-Chain Amino Acid-Related Metabolic Signature that Differentiates Obese and Lean Humans and Contributes to Insulin Resistance

(2009) Christopher B. Newgard et al.   Cell Metabolism

Leucine Supplementation of Drinking Water Does Not Alter Susceptibility to Diet-Induced Obesity in Mice

(2009) Ali Nairizi et al.   JOURNAL OF NUTRITION

Dietary l-Arginine Supplementation Reduces White Fat Gain and Enhances Skeletal Muscle and Brown Fat Masses in Diet-Induced Obese Rats

(2008) Wenjuan Jobgen et al.   JOURNAL OF NUTRITION