标题
Discovery of highly neutralizing human antibodies targeting Pseudomonas aeruginosa
作者
关键词
-
出版物
CELL
Volume -, Issue -, Pages -
出版商
Elsevier BV
发表日期
2023-11-01
DOI
10.1016/j.cell.2023.10.002
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Pharmacokinetics and Pharmacodynamics (PK/PD) of Corallopyronin A against Methicillin-Resistant Staphylococcus aureus
- (2023) Katharina Rox et al. Pharmaceutics
- Global burden of bacterial antimicrobial resistance in 2019: a systematic analysis
- (2022) Christopher JL Murray et al. LANCET
- Virulence Factors of Pseudomonas Aeruginosa and Antivirulence Strategies to Combat Its Drug Resistance
- (2022) Chongbing Liao et al. Frontiers in Cellular and Infection Microbiology
- Patient-derived monoclonal antibody neutralizes SARS-CoV-2 Omicron variants and confers full protection in monkeys
- (2022) Craig Fenwick et al. Nature Microbiology
- StarMap: a user-friendly workflow for Rosetta-driven molecular structure refinement
- (2022) Wolfgang Lugmayr et al. Nature Protocols
- Bacteriophage-antibiotic combination therapy against extensively drug-resistant Pseudomonas aeruginosa infection to allow liver transplantation in a toddler
- (2022) Brieuc Van Nieuwenhuyse et al. Nature Communications
- Influence of tramadol on bacterial burden in the standard neutropenic thigh infection model
- (2022) K. Rox Scientific Reports
- Human antibodies targeting a Mycobacterium transporter protein mediate protection against tuberculosis
- (2021) Avia Watson et al. Nature Communications
- Highly accurate protein structure prediction with AlphaFold
- (2021) John Jumper et al. NATURE
- Effective high-throughput isolation of fully human antibodies targeting infectious pathogens
- (2021) Lutz Gieselmann et al. Nature Protocols
- Early Treatment for Covid-19 with SARS-CoV-2 Neutralizing Antibody Sotrovimab
- (2021) Anil Gupta et al. NEW ENGLAND JOURNAL OF MEDICINE
- Restriction of HIV-1 Escape by a Highly Broad and Potent Neutralizing Antibody
- (2020) Philipp Schommers et al. CELL
- openPrimeR for multiplex amplification of highly diverse templates
- (2020) Christoph Kreer et al. JOURNAL OF IMMUNOLOGICAL METHODS
- Comprehensive Host Cell-Based Screening Assays for Identification of Anti-Virulence Drugs Targeting Pseudomonas aeruginosa and Salmonella Typhimurium
- (2020) Julia von Ambüren et al. Microorganisms
- UCSF ChimeraX : Structure visualization for researchers, educators, and developers
- (2020) Eric F. Pettersen et al. PROTEIN SCIENCE
- Pseudomonas aeruginosa adaptation and evolution in patients with cystic fibrosis
- (2020) Elio Rossi et al. NATURE REVIEWS MICROBIOLOGY
- Monoclonal antibody-based therapies for bacterial infections
- (2019) Michael P. Motley et al. CURRENT OPINION IN INFECTIOUS DISEASES
- Genetically diverse Pseudomonas aeruginosa populations display similar transcriptomic profiles in a cystic fibrosis explanted lung
- (2019) Adrian Kordes et al. Nature Communications
- Specific antibodies to membrane proteins are effective in complement-mediated killing of Mycoplasma bovis
- (2019) Yun-ke Zhang et al. INFECTION AND IMMUNITY
- Macromolecular structure determination using X-rays, neutrons and electrons: recent developments in Phenix
- (2019) Dorothee Liebschner et al. Acta Crystallographica Section D-Structural Biology
- Polyclonal and convergent antibody response to Ebola virus vaccine rVSV-ZEBOV
- (2019) Stefanie A. Ehrhardt et al. NATURE MEDICINE
- Adapting to the Airways: Metabolic Requirements of Pseudomonas aeruginosa during the Infection of Cystic Fibrosis Patients
- (2019) La Rosa et al. Metabolites
- A Randomized, Controlled Trial of Ebola Virus Disease Therapeutics
- (2019) Sabue Mulangu et al. NEW ENGLAND JOURNAL OF MEDICINE
- Long-term Microevolution of Pseudomonas aeruginosa Differs Between Mildly and Severely Affected Cystic Fibrosis Lungs
- (2018) Jens Klockgether et al. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
- KB001-A, a novel anti-inflammatory, found to be safe and well-tolerated in cystic fibrosis patients infected with Pseudomonas aeruginosa
- (2018) R. Jain et al. Journal of Cystic Fibrosis
- Cross-specificity of protective human antibodies against Klebsiella pneumoniae LPS O-antigen
- (2018) Tim Rollenske et al. NATURE IMMUNOLOGY
- Phase 1 study of MEDI3902, an investigational anti–Pseudomonas aeruginosa PcrV and Psl bispecific human monoclonal antibody, in healthy adults
- (2018) S.O. Ali et al. CLINICAL MICROBIOLOGY AND INFECTION
- Human Neutralizing Monoclonal Antibody Inhibition of Middle East Respiratory Syndrome Coronavirus Replication in the Common Marmoset
- (2017) Zhe Chen et al. JOURNAL OF INFECTIOUS DISEASES
- Antibody 10-1074 suppresses viremia in HIV-1-infected individuals
- (2017) Marina Caskey et al. NATURE MEDICINE
- Host-directed therapies for bacterial and viral infections
- (2017) Stefan H. E. Kaufmann et al. NATURE REVIEWS DRUG DISCOVERY
- Immune stealth-driven O2 serotype prevalence and potential for therapeutic antibodies against multidrug resistant Klebsiella pneumoniae
- (2017) Meghan E. Pennini et al. Nature Communications
- Obiltoxaximab Prevents Disseminated Bacillus anthracis Infection and Improves Survival during Pre- and Postexposure Prophylaxis in Animal Models of Inhalational Anthrax
- (2016) Brent J. Yamamoto et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Obiltoxaximab: First Global Approval
- (2016) Sarah L. Greig DRUGS
- Novel Strategies for the Treatment of Pseudomonas aeruginosa Infections
- (2016) Stefanie Wagner et al. JOURNAL OF MEDICINAL CHEMISTRY
- Epitope specificity plays a critical role in regulating antibody-dependent cell-mediated cytotoxicity against influenza A virus
- (2016) Wenqian He et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Protective monotherapy against lethal Ebola virus infection by a potently neutralizing antibody
- (2016) D. Corti et al. SCIENCE
- Pseudomonas aeruginosaBacteremic Patients Exhibit Nonprotective Antibody Titers Against Therapeutic Antibody Targets PcrV and Psl Exopolysaccharide
- (2015) Joshua T. Thaden et al. JOURNAL OF INFECTIOUS DISEASES
- CTFFIND4: Fast and accurate defocus estimation from electron micrographs
- (2015) Alexis Rohou et al. JOURNAL OF STRUCTURAL BIOLOGY
- Antibacterial antibodies gain traction
- (2015) Chris Morrison NATURE REVIEWS DRUG DISCOVERY
- A common glycan structure on immunoglobulin G for enhancement of effector functions
- (2015) Chin-Wei Lin et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Approval of Raxibacumab for the Treatment of Inhalation Anthrax Under the US Food and Drug Administration “Animal Rule”
- (2015) Chia-Wei Tsai et al. Frontiers in Microbiology
- A Novel Anti-PcrV Antibody Providing Enhanced Protection against Pseudomonas aeruginosa in Multiple Animal Infection Models
- (2014) Paul Warrener et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- A multifunctional bispecific antibody protects against Pseudomonas aeruginosa
- (2014) A. DiGiandomenico et al. Science Translational Medicine
- IgG Subclasses and Allotypes: From Structure to Effector Functions
- (2014) Gestur Vidarsson et al. Frontiers in Immunology
- Asymmetrical Fc Engineering Greatly Enhances Antibody-dependent Cellular Cytotoxicity (ADCC) Effector Function and Stability of the Modified Antibodies
- (2013) Zhi Liu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- IgBLAST: an immunoglobulin variable domain sequence analysis tool
- (2013) Jian Ye et al. NUCLEIC ACIDS RESEARCH
- Safety and pharmacokinetics of an anti-PcrV PEGylated monoclonal antibody fragment in mechanically ventilated patients colonized with Pseudomonas aeruginosa
- (2012) Bruno François et al. CRITICAL CARE MEDICINE
- ExoS and ExoT ADP Ribosyltransferase Activities Mediate Pseudomonas aeruginosa Keratitis by Promoting Neutrophil Apoptosis and Bacterial Survival
- (2012) Y. Sun et al. JOURNAL OF IMMUNOLOGY
- RELION: Implementation of a Bayesian approach to cryo-EM structure determination
- (2012) Sjors H.W. Scheres JOURNAL OF STRUCTURAL BIOLOGY
- NIH Image to ImageJ: 25 years of image analysis
- (2012) Caroline A Schneider et al. NATURE METHODS
- Fast, scalable generation of high-quality protein multiple sequence alignments using Clustal Omega
- (2011) F. Sievers et al. Molecular Systems Biology
- The safety and side effects of monoclonal antibodies
- (2010) Trevor T. Hansel et al. NATURE REVIEWS DRUG DISCOVERY
- Anti-virulence strategies to combat bacteria-mediated disease
- (2010) David A. Rasko et al. NATURE REVIEWS DRUG DISCOVERY
- Treatment with Monoclonal Antibodies againstClostridium difficileToxins
- (2010) Israel Lowy et al. NEW ENGLAND JOURNAL OF MEDICINE
- MolProbity: all-atom structure validation for macromolecular crystallography
- (2009) Vincent B. Chen et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- Role of Pseudomonas aeruginosa type III effectors in disease
- (2009) Joanne Engel et al. CURRENT OPINION IN MICROBIOLOGY
- The type III secretion system of Pseudomonas aeruginosa: infection by injection
- (2009) Alan R. Hauser NATURE REVIEWS MICROBIOLOGY
- Raxibacumab for the Treatment of Inhalational Anthrax
- (2009) Thi-Sau Migone et al. NEW ENGLAND JOURNAL OF MEDICINE
- Antibody response toPseudomonas aeruginosain children with cystic fibrosis
- (2009) Lucimar G. Milagres et al. PEDIATRIC PULMONOLOGY
- Persistent Infection withPseudomonas aeruginosain Ventilator-associated Pneumonia
- (2008) Ali A. El Solh et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- An Engineered Human Antibody Fab Fragment Specific for Pseudomonas aeruginosa PcrV Antigen Has Potent Antibacterial Activity
- (2008) M. Baer et al. INFECTION AND IMMUNITY
- Efficient generation of monoclonal antibodies from single human B cells by single cell RT-PCR and expression vector cloning
- (2007) Thomas Tiller et al. JOURNAL OF IMMUNOLOGICAL METHODS
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreDiscover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversation