Comprehensive Host Cell-Based Screening Assays for Identification of Anti-Virulence Drugs Targeting Pseudomonas aeruginosa and Salmonella Typhimurium

Host Cell Death Responses to Non-typhoidal Salmonella Infection

(2019) Madeleine A. Wemyss et al.   Frontiers in Immunology

Indole-core-based novel antibacterial agent targeting FtsZ

(2019) Wenchang Yuan et al.   Infection and Drug Resistance

Quinazoline-Based Antivirulence Compounds Selectively Target Salmonella PhoP/PhoQ Signal Transduction System

(2019) María Ayelén Carabajal et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Sphingolipids as targets for inhalation treatment of cystic fibrosis

(2018) Katrin Anne Becker et al.   ADVANCED DRUG DELIVERY REVIEWS

Discovery, research, and development of new antibiotics: the WHO priority list of antibiotic-resistant bacteria and tuberculosis

(2018) Evelina Tacconelli et al.   LANCET INFECTIOUS DISEASES

The microbiota metabolite indole inhibits Salmonella virulence: Involvement of the PhoPQ two-component system

(2018) Nandita Kohli et al.   PLoS One

Identification of FDA-approved drugs as antivirulence agents targeting the pqs quorum sensing system of Pseudomonas aeruginosa

(2018) Francesca D'Angelo et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Alterations of Salmonella enterica Serovar Typhimurium Antibiotic Resistance under Environmental Pressure

(2018) Mengfei Peng et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Antibiotic resistance in Pseudomonas aeruginosa: mechanisms and alternative therapeutic strategies

(2018) Zheng Pang et al.   BIOTECHNOLOGY ADVANCES

Attributable deaths and disability-adjusted life-years caused by infections with antibiotic-resistant bacteria in the EU and the European Economic Area in 2015: a population-level modelling analysis

(2018) Alessandro Cassini et al.   LANCET INFECTIOUS DISEASES

A Systematic Review of the Incidence, Risk Factors and Case Fatality Rates of Invasive Nontyphoidal Salmonella (iNTS) Disease in Africa (1966 to 2014)

(2017) Ifeanyi Valentine Uche et al.   PLoS Neglected Tropical Diseases

Quercetin Inhibits Inflammasome Activation by Interfering with ASC Oligomerization and Prevents Interleukin-1 Mediated Mouse Vasculitis

(2017) Talita P. Domiciano et al.   Scientific Reports

Targeting the Type Three Secretion System in Pseudomonas aeruginosa

(2016) Ahalieyah Anantharajah et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Small-Molecule Inhibitors of the Type III Secretion System

(2015) Lingling Gu et al.   MOLECULES

Lansoprazole is an antituberculous prodrug targeting cytochrome bc1

(2015) Jan Rybniker et al.   Nature Communications

Platforms for antibiotic discovery

(2013) Kim Lewis   NATURE REVIEWS DRUG DISCOVERY

ExoS and ExoT ADP Ribosyltransferase Activities Mediate Pseudomonas aeruginosa Keratitis by Promoting Neutrophil Apoptosis and Bacterial Survival

(2012) Y. Sun et al.   JOURNAL OF IMMUNOLOGY

Effects of indole on drug resistance and virulence of Salmonella enterica serovar Typhimurium revealed by genome-wide analyses

(2012) Eiji Nikaido et al.   Gut Pathogens

Functional Inhibitors of Acid Sphingomyelinase (FIASMAs): A Novel Pharmacological Group of Drugs with Broad Clinical Applications

(2010) Johannes Kornhuber et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Redundant roles for inflammasome receptors NLRP3 and NLRC4 in host defense againstSalmonella

(2010) Petr Broz et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Glyburide inhibits the Cryopyrin/Nalp3 inflammasome

(2009) Mohamed Lamkanfi et al.   JOURNAL OF CELL BIOLOGY

An Inhibitor of Gram-Negative Bacterial Virulence Protein Secretion

(2008) Heather B. Felise et al.   Cell Host & Microbe

Indole and 7-hydroxyindole diminishPseudomonas aeruginosavirulence

(2008) Jintae Lee et al.   Microbial Biotechnology