Natural and Engineered Isoforms of the Inflammasome Adaptor ASC Form Noncovalent, pH-Responsive Hydrogels

Comparison of Physicochemical Properties of Native Mucus and Reconstituted Mucin Gels

(2023) Caroline E. Wagner et al.   Biomacromolecules

Orchestrating Chemical and Physical Cross-Linking in Protein Hydrogels to Regulate Embryonic Stem Cell Growth

(2023) Tingting Yang et al.   ACS Macro Letters

Inflammasome regulation by adaptor isoforms, ASC and ASCb, via differential self-assembly

(2022) Pedro Diaz-Parga et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Spidroin N-terminal domain forms amyloid-like fibril based hydrogels and provides a protein immobilization platform

(2022) Tina Arndt et al.   Nature Communications

Natural and engineered inflammasome adapter proteins reveal optimum linker length for self-assembly

(2022) Pedro Diaz-Parga et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structure, Activation and Regulation of NLRP3 and AIM2 Inflammasomes

(2021) Meenakshi Sharma et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

On-Demand Regulation of Dual Thermosensitive Protein Hydrogels

(2021) Wen-Wen Song et al.   ACS Macro Letters

A comprehensive interaction study provides a potential domain interaction network of human death domain superfamily proteins

(2021) Wei Zhou et al.   CELL DEATH AND DIFFERENTIATION

Protein Hydrogels: The Swiss Army Knife for Enhanced Mechanical and Bioactive Properties of Biomaterials

(2021) Carla Huerta-López et al.   Nanomaterials

Elastin-Based Thermoresponsive Shape-Memory Hydrogels

(2020) Yuancheng Zhang et al.   BIOMACROMOLECULES

Temperature-Responsive Multifunctional Protein Hydrogels with Elastin-like Polypeptides for 3-D Angiogenesis

(2020) Yoshinori Mizuguchi et al.   BIOMACROMOLECULES

100th Anniversary of Macromolecular Science Viewpoint: Synthetic Protein Hydrogels

(2020) Ying Li et al.   ACS Macro Letters

Single-Molecule Studies of Protein Folding with Optical Tweezers

(2020) Carlos Bustamante et al.   Annual Review of Biochemistry

Network Growth and Structural Characteristics of Globular Protein Hydrogels

(2020) Benjamin S. Hanson et al.   MACROMOLECULES

UCSF ChimeraX : Structure visualization for researchers, educators, and developers

(2020) Eric F. Pettersen et al.   PROTEIN SCIENCE

Heterotypic Supramolecular Hydrogels Formed by Noncovalent Interactions in Inflammasomes

(2020) Adrianna N. Shy et al.   MOLECULES

Structure, interactions and self-assembly of ASC-dependent inflammasomes

(2019) Eva de Alba   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Rationally designed synthetic protein hydrogels with predictable mechanical properties

(2018) Junhua Wu et al.   Nature Communications

The inflammasome adapter ASC assembles into filaments with integral participation of its two Death Domains, PYD and CARD

(2018) Reinard Jeffrey T. Nambayan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cryo-EM structures of ASC and NLRC4 CARD filaments reveal a unified mechanism of nucleation and activation of caspase-1

(2018) Yang Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Functional Self-Assembling Peptide Nanofiber Hydrogels Designed for Nerve Degeneration

(2016) Yuqiao Sun et al.   ACS Applied Materials & Interfaces

ASC Pyrin Domain Self-associates and Binds NLRP3 Protein Using Equivalent Binding Interfaces

(2016) Javier Oroz et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Collagen and Elastin Biomaterials for the Fabrication of Engineered Living Tissues

(2016) David Miranda-Nieves et al.   ACS Biomaterials-Science & Engineering

Collagen and Elastin Biomaterials for the Fabrication of Engineered Living Tissues

(2016) David Miranda-Nieves et al.   ACS Biomaterials Science & Engineering

Dual Thermosensitive Hydrogels Assembled from the Conserved C-Terminal Domain of Spider Dragline Silk

(2015) Zhi-Gang Qian et al.   BIOMACROMOLECULES

Interaction Networks in Protein Folding via Atomic-Resolution Experiments and Long-Time-Scale Molecular Dynamics Simulations

(2015) Lorenzo Sborgi et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

I-TASSER server: new development for protein structure and function predictions

(2015) Jianyi Yang et al.   NUCLEIC ACIDS RESEARCH

Engineered Coiled-Coil Protein Microfibers

(2014) Jasmin Hume et al.   BIOMACROMOLECULES

Unified Polymerization Mechanism for the Assembly of ASC-Dependent Inflammasomes

(2014) Alvin Lu et al.   CELL

The NLRP3 inflammasome is released as a particulate danger signal that amplifies the inflammatory response

(2014) Alberto Baroja-Mazo et al.   NATURE IMMUNOLOGY

Two-Component Protein Hydrogels Assembled Using an Engineered Disulfide-Forming Protein–Ligand Pair

(2013) Dongli Guan et al.   BIOMACROMOLECULES

Forced protein unfolding leads to highly elastic and tough protein hydrogels

(2013) Jie Fang et al.   Nature Communications

Peptide tag forming a rapid covalent bond to a protein, through engineering a bacterial adhesin

(2012) B. Zakeri et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Biopolymer-Based Hydrogels As Scaffolds for Tissue Engineering Applications: A Review

(2011) S. Van Vlierberghe et al.   BIOMACROMOLECULES

Injectable shear-thinning hydrogels engineered with a self-assembling Dock-and-Lock mechanism

(2011) Hoang D. Lu et al.   BIOMATERIALS

Peptide- and Protein-Based Hydrogels

(2011) Anika M. Jonker et al.   CHEMISTRY OF MATERIALS

Protein Engineering in the Development of Functional Hydrogels

(2010) Scott Banta et al.   Annual Review of Biomedical Engineering

Differential splicing of the apoptosis-associated speck like protein containing a caspase recruitment domain (ASC) regulates inflammasomes

(2010) Nicole B Bryan et al.   Journal of Inflammation-London

Structure and Interdomain Dynamics of Apoptosis-associated Speck-like Protein Containing a CARD (ASC)

(2009) Eva de Alba   JOURNAL OF BIOLOGICAL CHEMISTRY

Two-component protein-engineered physical hydrogels for cell encapsulation

(2009) Cheryl T. S. Wong Po Foo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA