Exploring the therapeutic potential of naturally occurring piceatannol in non‐communicable diseases

Piceatannol protects against sepsis-induced myocardial dysfunction via direct inhibition of JAK2

(2021) Lingpeng Xie et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Piceatannol: A natural stilbene for the prevention and treatment of cancer

(2020) Kishore Banik et al.   PHARMACOLOGICAL RESEARCH

Albumin Nano-Encapsulation of Piceatannol Enhances Its Anticancer Potential in Colon Cancer Via Downregulation of Nuclear p65 and HIF-1α

(2020) Alaa A. A. Aljabali et al.   Cancers

Piceatannol-Loaded Emulsomes Exhibit Enhanced Cytostatic and Apoptotic Activities in Colon Cancer Cells

(2020) Nabil A. Alhakamy et al.   Antioxidants

Non-nutrients and nutrients from Latin American fruits for the prevention of cardiovascular diseases

(2020) Lais Marinho Aguiar et al.   FOOD RESEARCH INTERNATIONAL

Inhibitory Effect of Piceatannol on Streptococcus suis Infection Both in vitro and in vivo

(2020) Guizhen Wang et al.   Frontiers in Microbiology

Effect of piceatannol on circadian Per2 expression in vitro and in vivo

(2019) Takayuki Yamamoto et al.   Journal of Functional Foods

Piceatannol alleviates inflammation and oxidative stress via modulation of the Nrf2/HO-1 and NF-κB pathways in diabetic cardiomyopathy

(2019) Hao Li et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Piceatannol Inhibits P. acnes–Induced Keratinocyte Proliferation and Migration by Downregulating Oxidative Stress and the Inflammatory Response

(2019) Tingting Zhu et al.   INFLAMMATION

Piceatannol Increases Antioxidant Defense and Reduces Cell Death in Human Periodontal Ligament Fibroblast under Oxidative Stress

(2019) Flávia Póvoa da Costa et al.   Antioxidants

Protective effects of piceatannol on methylglyoxal-induced cytotoxicity in MC3T3-E1 osteoblastic cells

(2018) Kwang Sik Suh et al.   FREE RADICAL RESEARCH

The Dietary Antioxidant Piceatannol Inhibits Adipogenesis of Human Adipose Mesenchymal Stem Cells and Limits Glucose Transport and Lipogenic Activities in Adipocytes

(2018) Christian Carpéné et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Chitosan/poly (lactic acid)-coated piceatannol nanoparticles exert an in vitro apoptosis activity on liver, lung and breast cancer cell lines

(2018) Jeevitha Dhanapal et al.   Artificial Cells Nanomedicine and Biotechnology

Functional consequences of piceatannol binding to glyceraldehyde-3-phosphate dehydrogenase

(2018) Joanna Gerszon et al.   PLoS One

Piceatannol pretreatment alleviates acute cardiac injury via regulating PI3K-Akt-eNOS signaling in H9c2 cells

(2018) Dapeng Wang et al.   BIOMEDICINE & PHARMACOTHERAPY

The antioxidative activity of piceatannol and its different derivatives: Antioxidative mechanism analysis

(2018) Yan-Zhen Zheng et al.   PHYTOCHEMISTRY

Highly regioselective hydroxylation of polydatin, a resveratrol glucoside, for one-step synthesis of astringin, a piceatannol glucoside, by P450 BM3

(2017) Thien-Kim Le et al.   ENZYME AND MICROBIAL TECHNOLOGY

A Theoretical Study on the Antioxidant Activity of Piceatannol and Isorhapontigenin Scavenging Nitric Oxide and Nitrogen Dioxide Radicals

(2017) Yang Lu et al.   PLoS One

Piceatannol inhibits the IL-1β-induced inflammatory response in human osteoarthritic chondrocytes and ameliorates osteoarthritis in mice by activating Nrf2

(2017) Qian Tang et al.   Food & Function

Piceatannol increases the expression of hepatocyte growth factor and IL-10 thereby protecting hepatocytes in thioacetamide-induced liver fibrosis

(2016) Hazem Abd-Elgawad et al.   CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY

Nanocomposite microparticles (nCmP) for the delivery of tacrolimus in the treatment of pulmonary arterial hypertension

(2016) Zimeng Wang et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Administration of Piceatannol Complexed with α-Cyclodextrin Improves Its Absorption in Rats

(2016) Hiroyuki Inagaki et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

A Comprehensive Review on the Chemotherapeutic Potential of Piceatannol for Cancer Treatment, with Mechanistic Insights

(2016) Mohamed Ali Seyed et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Piceatannol and Other Wine Stilbenes: A Pool of Inhibitors against α-Synuclein Aggregation and Cytotoxicity

(2016) Hamza Temsamani et al.   Nutrients

Piceatannol exhibits anti-inflammatory effects on macrophages interacting with adipocytes

(2016) Takayuki Yamamoto et al.   Food Science & Nutrition

Enhanced endoplasmic reticulum stress in bone marrow angiogenic progenitor cells in a mouse model of long-term experimental type 2 diabetes

(2015) Maulasri Bhatta et al.   DIABETOLOGIA

Inhibition of tumor progression by oral piceatannol in mouse 4T1 mammary cancer is associated with decreased angiogenesis and macrophage infiltration

(2015) Hyerim Song et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Piceatannol Enhances the Antitumor Efficacy of Gemcitabine in Human A549 Non-Small Cell Lung Cancer Cells

(2015) Bin Xu et al.   ONCOLOGY RESEARCH

Piceatannol promotes apoptosis via up-regulation of microRNA-129 expression in colorectal cancer cell lines

(2014) Haogang Zhang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Piceatannol inhibits phorbol ester-induced expression of COX-2 and iNOS in HR-1 hairless mouse skin by blocking the activation of NF-κB and AP-1

(2014) Lijia Liu et al.   INFLAMMATION RESEARCH

Absorption and Metabolism of Piceatannol in Rats

(2014) Yuko Setoguchi et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Chemistry: Chemical con artists foil drug discovery

(2014) Jonathan Baell et al.   NATURE

A Review of the Pharmacological Effects of Piceatannol on Cardiovascular Diseases

(2014) Yee-Ling Tang et al.   PHYTOTHERAPY RESEARCH

Piceatannol and Its Metabolite, Isorhapontigenin, Induce SIRT1 Expression in THP-1 Human Monocytic Cell Line

(2014) Shinpei Kawakami et al.   Nutrients

Involvement of heme oxygenase-1 expression in neuroprotection by piceatannol, a natural analog and a metabolite of resveratrol, against glutamate-mediated oxidative injury in HT22 neuronal cells

(2013) Yong Son et al.   AMINO ACIDS

Differential effects of resveratrol and its natural analogs, piceatannol and 3,5,4′-trans-trimethoxystilbene, on anti-inflammatory heme oxigenase-1 expression in RAW264.7 macrophages

(2013) Yong Son et al.   BIOFACTORS

Piceatannol facilitates conduction block and ventricular fibrillation induction in ischemia-reperfused rabbit hearts with pacing-induced heart failure

(2013) Chung-Chuan Chou et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Piceatannol suppresses the metastatic potential of MCF10A human breast epithelial cells harboring mutated H-ras by inhibiting MMP-2 expression

(2013) NURY SONG et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Piceatannol inhibits mast cell-mediated allergic inflammation

(2013) YU-JIN KO et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Piceatannol, a better peroxyl radical scavenger than resveratrol

(2013) Moises Cordova-Gomez et al.   RSC Advances

Piceatannol, a resveratrol derivative, promotes glucose uptake through glucose transporter 4 translocation to plasma membrane in L6 myocytes and suppresses blood glucose levels in type 2 diabetic model db/db mice

(2012) Miki Minakawa et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Piceatannol, Natural Polyphenolic Stilbene, Inhibits Adipogenesis via Modulation of Mitotic Clonal Expansion and Insulin Receptor-dependent Insulin Signaling in Early Phase of Differentiation

(2012) Jung Yeon Kwon et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Antiproliferative and Anti-Invasive Effect of Piceatannol, a Polyphenol Present in Grapes and Wine, against Hepatoma AH109A Cells

(2012) Yuichiro Kita et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Piceatannol is more effective than resveratrol in restoring endothelial cell dimethylarginine dimethylaminohydrolase expression and activity after high-glucose oxidative stress

(2011) Matthieu Frombaum et al.   FREE RADICAL RESEARCH

Biological activity of piceatannol: Leaving the shadow of resveratrol

(2011) Hanna Piotrowska et al.   MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH

Piceatannol induces Fas and FasL up-regulation in human leukemia U937 cells via Ca2+/p38α MAPK-mediated activation of c-Jun and ATF-2 pathways

(2010) Wen-Hsin Liu et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Extract of Passion Fruit (Passiflora edulis) Seed Containing High Amounts of Piceatannol Inhibits Melanogenesis and Promotes Collagen Synthesis

(2010) Yuko Matsui et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Glucuronidation of piceatannol by human liver microsomes: major role of UGT1A1, UGT1A8 and UGT1A10

(2010) Michaela Miksits et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

Piceatannol enhances TRAIL-induced apoptosis in human leukemia THP-1 cells through Sp1- and ERK-dependent DR5 up-regulation

(2010) Chang-Hee Kang et al.   TOXICOLOGY IN VITRO

Piceatannol, a natural stilbene from grapes, induces G1 cell cycle arrest in androgen-insensitive DU145 human prostate cancer cells via the inhibition of CDK activity

(2009) Yeo Myeong Lee et al.   CANCER LETTERS

Pro- and anticarcinogenic mechanisms of piceatannol are activated dose dependently in MCF-7 breast cancer cells

(2009) Nha T.P. Vo et al.   CARCINOGENESIS

Analysis of Flavonoid-Based Pharmacophores that Inhibit Aggrecanases (ADAMTS-4 and ADAMTS-5) and Matrix Metalloproteinases Through the Use of Topologically Constrained Peptide Substrates

(2009) Mare Cudic et al.   Chemical Biology & Drug Design

A simple and sensitive HPLC-UV method for the quantification of piceatannol analog trans-3,5,3′,4′-tetramethoxystilbene in rat plasma and its application for a pre-clinical pharmacokinetic study

(2009) Hai-Shu Lin et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

In-vitro sulfation of piceatannol by human liver cytosol and recombinant sulfotransferases

(2009) Michaela Miksits et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

Resveratrol and Piceatannol Inhibit iNOS Expression and NF-κ B Activation in Dextran Sulfate Sodium-Induced Mouse Colitis

(2009) Jin Youn et al.   NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL

Piceatannol Inhibits Phorbol Ester-Induced NF-κ B Activation and COX-2 Expression in Cultured Human Mammary Epithelial Cells

(2009) Dan Liu et al.   NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL