Serinc2 deficiency exacerbates sepsis-induced cardiomyopathy by enhancing necroptosis and apoptosis

Integrative Methylome and Transcriptome Characterization Identifies SERINC2 as a Tumor-Driven Gene for Papillary Thyroid Carcinoma

(2023) Tianxing Ying et al.   Cancers

MLKL Regulates Rapid Cell Death-independent HMGB1 Release in RSV Infected Airway Epithelial Cells

(2022) Jennifer Simpson et al.   Frontiers in Cell and Developmental Biology

Serinc2 deficiency causes susceptibility to sepsis-associated acute lung injury

(2022) Shuai Mao et al.   Journal of Inflammation-London

Pathophysiology of sepsis-induced cardiomyopathy

(2021) Steven M. Hollenberg et al.   Nature Reviews Cardiology

Necroptosis, pyroptosis and apoptosis: an intricate game of cell death

(2021) Damien Bertheloot et al.   Cellular & Molecular Immunology

SERINC2 increases the risk of bipolar disorder in the Chinese population

(2021) Dong Yang et al.   DEPRESSION AND ANXIETY

CpG Oligodeoxynucleotides Induces Apoptosis of Human Bladder Cancer Cells via Caspase-3-Bax/Bcl-2-p53 Axis

(2020) Yang Luo et al.   ARCHIVES OF MEDICAL RESEARCH

Crosstalk between GSK-3β-actuated molecular cascades and myocardial physiology

(2020) Arun K. Sharma et al.   HEART FAILURE REVIEWS

The Anti-inflammatory Mediator Resolvin E1 Protects Mice Against Lipopolysaccharide-Induced Heart Injury

(2020) Jishou Zhang et al.   Frontiers in Pharmacology

Ribonuclease 1 attenuates septic cardiomyopathy and cardiac apoptosis in a murine model of polymicrobial sepsis

(2020) Elisabeth Zechendorf et al.   JCI Insight

The AMPAR antagonist perampanel regulates neuronal necroptosis via Akt/GSK3β signaling after acute traumatic injury in cortical neurons

(2020) Tao Chen et al.   CNS & Neurological Disorders-Drug Targets

Drp1/Fis1 interaction mediates mitochondrial dysfunction in septic cardiomyopathy

(2019) Bereketeab Haileselassie et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

FNDC5 alleviates oxidative stress and cardiomyocyte apoptosis in doxorubicin-induced cardiotoxicity via activating AKT

(2019) Xin Zhang et al.   CELL DEATH AND DIFFERENTIATION

The Structure of the Necrosome RIPK1-RIPK3 Core, a Human Hetero-Amyloid Signaling Complex

(2018) Miguel Mompeán et al.   CELL

Septic Cardiomyopathy

(2018) Sarah J. Beesley et al.   CRITICAL CARE MEDICINE

The Role of Necroptosis in Cardiovascular Disease

(2018) Shi Zhe-Wei et al.   Frontiers in Pharmacology

Puerarin attenuates neurological deficits via Bcl-2/Bax/cleaved caspase-3 and Sirt3/SOD2 apoptotic pathways in subarachnoid hemorrhage mice

(2018) Yu Zhang et al.   BIOMEDICINE & PHARMACOTHERAPY

Necroptosis and RIPK1-mediated neuroinflammation in CNS diseases

(2018) Junying Yuan et al.   NATURE REVIEWS NEUROSCIENCE

Deficiency of receptor-interacting protein kinase 3 (RIPK3) attenuates inflammation and organ injury in neonatal sepsis

(2017) Laura W. Hansen et al.   JOURNAL OF PEDIATRIC SURGERY

Chromosomal microarray analysis in a cohort of underrepresented population identifies SERINC2 as a novel candidate gene for autism spectrum disorder

(2017) Areerat Hnoonual et al.   Scientific Reports

Indirubin-3-Oxime Prevents H2O2-Induced Neuronal Apoptosis via Concurrently Inhibiting GSK3β and the ERK Pathway

(2016) Jie Yu et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Glycogen Synthase Kinase-3β and Caspase-2 Mediate Ceramide- and Etoposide-Induced Apoptosis by Regulating the Lysosomal-Mitochondrial Axis

(2016) Chiou-Feng Lin et al.   PLoS One

The Pseudokinase MLKL Mediates Necroptosis via a Molecular Switch Mechanism

(2013) James M. Murphy et al.   IMMUNITY