A risk-aware assessment for buffer recycling across unit operations for monoclonal antibody purification and its potential.

Continuous precipitation of antibodies using oscillatory flow reactor: A proof of concept

(2023) Diogo Ferreira-Faria et al.   SEPARATION AND PURIFICATION TECHNOLOGY

Streamlined life cycle assessment of single use technologies in biopharmaceutical manufacture

(2022) Kristi Budzinski et al.   New Biotechnology

Residence time distribution in counter-current protein A affinity chromatography using an inert tracer

(2022) Narges Lali et al.   JOURNAL OF CHROMATOGRAPHY A

An integrated continuous downstream process with real‐time control: A case study with periodic countercurrent chromatography and continuous virus inactivation

(2021) Anton Löfgren et al.   BIOTECHNOLOGY AND BIOENGINEERING

Process Analytical Technology for Precipitation Process Integration into Biologics Manufacturing towards Autonomous Operation—mAb Case Study

(2021) Lara Julia Lohmann et al.   Processes

Rinsing Recommendations for Membrane Filters and Identification of Rinsables

(2021) Roberto Menzel et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Continuous capture of recombinant antibodies by ZnCl 2 precipitation without polyethylene glycol

(2020) Gregory Dutra et al.   ENGINEERING IN LIFE SCIENCES

Optimization study on periodic counter-current chromatography integrated in a monoclonal antibody downstream process

(2020) Joaquín Gomis-Fons et al.   JOURNAL OF CHROMATOGRAPHY A

Continuous integrated antibody precipitation with two-stage tangential flow microfiltration enables constant mass flow

(2019) Daniel Burgstaller et al.   BIOTECHNOLOGY AND BIOENGINEERING

Protein A chromatography: Challenges and progress in the purification of monoclonal antibodies

(2019) Ana Mayela Ramos‐de‐la‐Peña et al.   JOURNAL OF SEPARATION SCIENCE

Precipitation of complex antibody solutions: influence of contaminant composition and cell culture medium on the precipitation behavior

(2019) Steffen Großhans et al.   BIOPROCESS AND BIOSYSTEMS ENGINEERING

Integrated flow-through purification for therapeutic monoclonal antibodies processing

(2018) Takamitsu Ichihara et al.   mAbs

Introduction of a process mass intensity metric for biologics

(2018) Kristi Budzinski et al.   New Biotechnology

The effect of feed quality due to clarification strategy on the design and performance of protein A periodic counter‐current chromatography

(2018) Hani El‐Sabbahy et al.   BIOTECHNOLOGY PROGRESS

Precipitation as an Enabling Technology for the Intensification of Biopharmaceutical Manufacture

(2018) Michael Martinez et al.   TRENDS IN BIOTECHNOLOGY

Investigation and prediction of protein precipitation by polyethylene glycol using quantitative structure–activity relationship models

(2017) Frank Hämmerling et al.   JOURNAL OF BIOTECHNOLOGY

Capture and intermediate purification of recombinant antibodies with combined precipitation methods

(2015) Ralf Sommer et al.   BIOCHEMICAL ENGINEERING JOURNAL

Robust depth filter sizing for centrate clarification

(2015) Herb Lutz et al.   BIOTECHNOLOGY PROGRESS

Buffer recycling in downstream processing of biologics

(2015) Alois Jungbauer et al.   Current Opinion in Chemical Engineering

Ethanol precipitation for purification of recombinant antibodies

(2014) Anne Tscheliessnig et al.   JOURNAL OF BIOTECHNOLOGY

Continuous separation of protein loaded nanoparticles by simulated moving bed chromatography

(2014) Peter Satzer et al.   JOURNAL OF CHROMATOGRAPHY A

Continuous processing of recombinant proteins: Integration of refolding and purification using simulated moving bed size-exclusion chromatography with buffer recycling

(2014) Martin Wellhoefer et al.   JOURNAL OF CHROMATOGRAPHY A

Continuous processing of recombinant proteins: Integration of inclusion body solubilization and refolding using simulated moving bed size exclusion chromatography with buffer recycling

(2013) Martin Wellhoefer et al.   JOURNAL OF CHROMATOGRAPHY A

Downstream of downstream processing: development of recycling strategies for biopharmaceutical processes

(2012) Florian Grote et al.   JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY

Predictive chromatographic simulations for the optimization of recovery and aggregate clearance during the capture of monoclonal antibodies

(2009) Mark Teeters et al.   JOURNAL OF CHROMATOGRAPHY A

New Developments in Simulated Moving Bed Chromatography

(2008) A. Seidel-Morgenstern et al.   CHEMICAL ENGINEERING & TECHNOLOGY