Precipitation of complex antibody solutions: influence of contaminant composition and cell culture medium on the precipitation behavior

An integrated precipitation and ion-exchange chromatography process for antibody manufacturing: Process development strategy and continuous chromatography exploration

(2018) Steffen Großhans et al.   JOURNAL OF CHROMATOGRAPHY A

Investigation and prediction of protein precipitation by polyethylene glycol using quantitative structure–activity relationship models

(2017) Frank Hämmerling et al.   JOURNAL OF BIOTECHNOLOGY

Osmolyte Effects on Monoclonal Antibody Stability and Concentration-Dependent Protein Interactions with Water and Common Osmolytes

(2016) Gregory V. Barnett et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Capture and intermediate purification of recombinant antibodies with combined precipitation methods

(2015) Ralf Sommer et al.   BIOCHEMICAL ENGINEERING JOURNAL

High-throughput micro-scale cultivations and chromatography modeling: Powerful tools for integrated process development

(2015) Pascal Baumann et al.   BIOTECHNOLOGY AND BIOENGINEERING

The business impact of an integrated continuous biomanufacturing platform for recombinant protein production

(2015) Jason Walther et al.   JOURNAL OF BIOTECHNOLOGY

The rise of biosimilars: potential benefits and drawbacks in rheumatoid arthritis

(2014) Dae Hyun Yoo   Expert Review of Clinical Immunology

Combined polyethylene glycol and CaCl2 precipitation for the capture and purification of recombinant antibodies

(2014) Ralf Sommer et al.   PROCESS BIOCHEMISTRY

Recovery of Chinese hamster ovary host cell proteins for proteomic analysis

(2013) Kristin N. Valente et al.   Biotechnology Journal

Alternative separation steps for monoclonal antibody purification: Combination of centrifugal partitioning chromatography and precipitation

(2013) Stefan A. Oelmeier et al.   JOURNAL OF CHROMATOGRAPHY A

Purification of antibodies by precipitating impurities using Polyethylene Glycol to enable a two chromatography step process

(2013) Glen Giese et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

The dynamics of the CHO host cell protein profile during clarification and protein A capture in a platform antibody purification process

(2012) Catherine E.M. Hogwood et al.   BIOTECHNOLOGY AND BIOENGINEERING

Studying host cell protein interactions with monoclonal antibodies using high throughput protein A chromatography

(2012) Vikram N. Sisodiya et al.   Biotechnology Journal

Forty years of research on osmolyte-induced protein folding and stability

(2012) L. R. Singh et al.   Journal of the Iranian Chemical Society

Host cell protein dynamics in the supernatant of a mAb producing CHO cell line

(2011) A.S. Tait et al.   BIOTECHNOLOGY AND BIOENGINEERING

Protein precipitation by polyethylene glycol: A generalized model based on hydrodynamic radius

(2011) Siow-Leng Sim et al.   JOURNAL OF BIOTECHNOLOGY

Advances in the production and downstream processing of antibodies

(2011) John H. Chon et al.   New Biotechnology

High-throughput screening techniques for rapid PEG-based precipitation of IgG4 mAb from clarified cell culture supernatant

(2009) Carol Knevelman et al.   BIOTECHNOLOGY PROGRESS

Depletion Theory and the Precipitation of Protein by Polymer†

(2009) Theo Odijk   JOURNAL OF PHYSICAL CHEMISTRY B