Novel insights into the augmented effect of curcumin and liraglutide in ameliorating cisplatin-induced nephrotoxicity in rats: Effects on oxidative stress, inflammation, apoptosis and pyroptosis via GSK-3β

Liraglutide abrogates nephrotoxic effects of chemotherapies

(2023) Cong Xu et al.   PHARMACOLOGICAL RESEARCH

Autophagy and necroptosis in cisplatin-induced acute kidney injury: Recent advances regarding their role and therapeutic potential

(2023) Noha Alassaf et al.   Frontiers in Pharmacology

Augmented nephroprotective effect of liraglutide and rabeprazole via inhibition of OCT2 transporter in cisplatin-induced nephrotoxicity in rats

(2023) Gehad Sharaf et al.   LIFE SCIENCES

TLR4/Inflammasomes Cross-Talk and Pyroptosis Contribute to N-Acetyl Cysteine and Chlorogenic Acid Protection against Cisplatin-Induced Nephrotoxicity

(2023) Amira M. Badr et al.   Pharmaceuticals

Nrf2-Related Therapeutic Effects of Curcumin in Different Disorders

(2022) Soudeh Ghafouri-Fard et al.   Biomolecules

GSK3β mediates the spatiotemporal dynamics of NLRP3 inflammasome activation

(2022) Suyavaran Arumugam et al.   CELL DEATH AND DIFFERENTIATION

Pro-Inflammatory Signalling PRRopels Cisplatin-Induced Toxicity

(2022) Ivan K. Domingo et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The Synergistic Effects of Curcumin and Chemotherapeutic Drugs in Inhibiting Metastatic, Invasive and Proliferative Pathways

(2022) Maria Younes et al.   Plants-Basel

The protective effects of curcumin on depression: Genes, transcription factors, and microRNAs involved

(2022) Hai Duc Nguyen et al.   JOURNAL OF AFFECTIVE DISORDERS

Rosmarinic Acid Prevents Cisplatin-Induced Liver and Kidney Injury by Inhibiting Inflammatory Responses and Enhancing Total Antioxidant Capacity, Thereby Activating the Nrf2 Signaling Pathway

(2022) Yifei Xiang et al.   MOLECULES

Natural products: potential treatments for cisplatin-induced nephrotoxicity

(2021) Chun-yan Fang et al.   ACTA PHARMACOLOGICA SINICA

PPAR-δ activation reduces cisplatin-induced apoptosis via inhibiting p53/Bax/caspase-3 pathway without modulating autophagy in murine renal proximal tubular cells

(2021) Juanping Shan et al.   Clinical and Experimental Nephrology

Liraglutide protects against lethal renal ischemia-reperfusion injury by inhibiting high-mobility group box 1 nuclear-cytoplasmic translocation and release

(2021) Yakun Li et al.   PHARMACOLOGICAL RESEARCH

Thymoquinone and curcumin combination protects cisplatin-induced kidney injury, nephrotoxicity by attenuating NFκB, KIM-1 and ameliorating Nrf2/HO-1 signalling

(2020) Majed Al Fayi et al.   JOURNAL OF DRUG TARGETING

Pantoprazole abrogated cisplatin-induced nephrotoxicity in mice via suppression of inflammation, apoptosis, and oxidative stress

(2020) Raed S. Ismail et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

Astragalus Polysaccharide Attenuates Cisplatin-Induced Acute Kidney Injury by Suppressing Oxidative Damage and Mitochondrial Dysfunction

(2020) Qing Ma et al.   Biomed Research International

Comparative nephroprotective effects of curcumin and etoricoxib against cisplatin-induced acute kidney injury in rats

(2020) Marwa Abd El-Kader et al.   ACTA HISTOCHEMICA

Liraglutide ameliorates obesity-related nonalcoholic fatty liver disease by regulating Sestrin2-mediated Nrf2/HO-1 pathway

(2020) Xue Han et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Curcumin: an inflammasome silencer

(2020) Shima Hassanzadeh et al.   PHARMACOLOGICAL RESEARCH

Gliclazide attenuates cisplatin‐induced nephrotoxicity through inhibiting NF‐κB and caspase‐3 activity

(2020) Fatemeh Taghizadeh et al.   IUBMB LIFE

Inflammasome activation and regulation: toward a better understanding of complex mechanisms

(2020) Danping Zheng et al.   Cell Discovery

COVID‐19: A Case for Inhibiting NLRP3 Inflammasome, Suppression of Inflammation with Curcumin?

(2020) Ali Saeedi‐Boroujeni et al.   BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY

The role of glycogen synthase kinase 3 beta in multiple sclerosis

(2020) Tayebeh Noori et al.   BIOMEDICINE & PHARMACOTHERAPY

Vitamin D/VDR attenuate cisplatin-induced AKI by down-regulating NLRP3/Caspase-1/GSDMD pyroptosis pathway

(2020) Siqing Jiang et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Recent advances in the mechanisms of NLRP3 inflammasome activation and its inhibitors

(2019) Yang Yang et al.   Cell Death & Disease

Targeting PI3K in cancer: mechanisms and advances in clinical trials

(2019) Jing Yang et al.   Molecular Cancer

The protective effects of liraglutide on AD-like neurodegeneration induced by oxidative stress in human neuroblastoma SH-SY5Y cells

(2019) Chen Zheng et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Farrerol Attenuates Cisplatin-Induced Nephrotoxicity by Inhibiting the Reactive Oxygen Species-Mediated Oxidation, Inflammation, and Apoptotic Signaling Pathways

(2019) Ning Ma et al.   Frontiers in Physiology

The glucagon-like peptide-1 (GLP-1) analog liraglutide attenuates renal fibrosis

(2018) Ya-Kun Li et al.   PHARMACOLOGICAL RESEARCH

Effect of combination sildenafil and gemfibrozil on cisplatin-induced nephrotoxicity; role of heme oxygenase-1

(2018) Safaa Behiry et al.   RENAL FAILURE

Persistent increase in mitochondrial superoxide mediates cisplatin-induced chronic kidney disease

(2018) Kranti A. Mapuskar et al.   Redox Biology

The effects of curcumin-containing supplements on biomarkers of inflammation and oxidative stress: A systematic review and meta-analysis of randomized controlled trials

(2018) Reza Tabrizi et al.   PHYTOTHERAPY RESEARCH

Nephroprotective Effects of Benzyl Isothiocyanate and Resveratrol Against Cisplatin-Induced Oxidative Stress and Inflammation

(2018) Abdelazim Ibrahim et al.   Frontiers in Pharmacology

TNF-α, IL-6 and IL-10 expressions, responsible for disparity in action of curcumin against cisplatin-induced nephrotoxicity in rats

(2017) Parveen Kumar et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Liraglutide restores chronic ER stress, autophagy impairments and apoptotic signalling in SH-SY5Y cells

(2017) Theodora Panagaki et al.   Scientific Reports

Activation of the NRF2-ARE signalling pathway by the Lentinula edodes polysaccharose LNT alleviates ROS-mediated cisplatin nephrotoxicity

(2016) Qian Chen et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Curcumin counteracts cisplatin-induced nephrotoxicity by preventing renal tubular cell apoptosis

(2016) Yeter Topcu-Tarladacalisir et al.   RENAL FAILURE

Protective effects of curcumin on acute gentamicin-induced nephrotoxicity in rats

(2015) Liyu He et al.   CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY

Aged garlic extract protects against oxidative stress and renal changes in cisplatin-treated adult male rats

(2014) Ashraf Y Nasr et al.   Cancer Cell International

Cisplatin in cancer therapy: Molecular mechanisms of action

(2014) Shaloam Dasari et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Activator or inhibitor? GSK-3 as a new drug target

(2013) Fumi Takahashi-Yanaga   BIOCHEMICAL PHARMACOLOGY

The small-molecule TNF-α inhibitor, UTL-5g, delays deaths and increases survival rates for mice treated with high doses of cisplatin

(2013) Jiajiu Shaw et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Inhibition of Cisplatin-Induced Lipid Catabolism and Weight Loss by Ghrelin in Male Mice

(2013) Jose M. Garcia et al.   ENDOCRINOLOGY

Effect of sildenafil in renal ischemia/reperfusion injury in rats

(2010) Paulo José de Medeiros et al.   Acta Cirurgica Brasileira

GSK3  Promotes Apoptosis after Renal Ischemic Injury

(2010) Z. Wang et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY