Phytosterol conversion into C9 non-hydroxylated derivatives through gene regulation in Mycobacterium fortuitum

Production of 21-hydroxy-20-methyl-pregna-1,4-dien-3-one by modifying multiple genes in Mycolicibacterium

(2023) Chenyang Yuan et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Loop pathways are responsible for tuning the accumulation of C19- and C22-sterol intermediates in the mycobacterial phytosterol degradation pathway

(2023) Shikui Song et al.   Microbial Cell Factories

Improving the production of 9α-hydroxy-4-androstene-3,17-dione from phytosterols by 3-ketosteroid-Δ1-dehydrogenase deletions and multiple genetic modifications in Mycobacterium fortuitum

(2023) Xiangcen Liu et al.   Microbial Cell Factories

Biotransformation of Phytosterols into Androstenedione—A Technological Prospecting Study

(2022) Victor Oliveira Nunes et al.   MOLECULES

Application of microbial 3-ketosteroid Δ1-dehydrogenases in biotechnology

(2021) Ali Rohman et al.   BIOTECHNOLOGY ADVANCES

Further Studies on the 3-Ketosteroid 9α-Hydroxylase of Rhodococcus ruber Chol-4, a Rieske Oxygenase of the Steroid Degradation Pathway

(2021) Sara Baldanta et al.   Microorganisms

Mycolicibacterium cell factory for the production of steroid-based drug intermediates

(2021) Anqi Zhao et al.   BIOTECHNOLOGY ADVANCES

Production of 9,21-dihydroxy-20-methyl-pregna-4-en-3-one from phytosterols in Mycobacterium neoaurum by modifying multiple genes and improving the intracellular environment

(2021) Chen-Yang Yuan et al.   Microbial Cell Factories

A Dual Role Reductase from Phytosterols Catabolism Enables the Efficient Production of Valuable Steroid Precursors

(2020) Haidong Peng et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Nitrate Metabolism Decreases the Steroidal Alcohol Byproduct Compared with Ammonium in Biotransformation of Phytosterol to Androstenedione by Mycobacterium neoaurum

(2019) Xuedong Wang et al.   APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY

Identification, function, and application of 3-ketosteroid Δ1-dehydrogenase isozymes in Mycobacterium neoaurum DSM 1381 for the production of steroidic synthons

(2018) Ruijie Zhang et al.   Microbial Cell Factories

New Insights on Steroid Biotechnology

(2018) Lorena Fernández-Cabezón et al.   Frontiers in Microbiology

Engineered 3-Ketosteroid 9α-Hydroxylases in Mycobacterium neoaurum : an Efficient Platform for Production of Steroid Drugs

(2018) Hao-Hao Liu et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Two-Step Bioprocess for Reducing Nucleus Degradation in Phytosterol Bioconversion by Mycobacterium neoaurum NwIB-R10hsd4A

(2018) Xuedong Wang et al.   APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY

Functional characterization of 3-ketosteroid 9α-hydroxylases in Rhodococcus ruber strain chol-4

(2017) Govinda Guevara et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Improving the production of 22-hydroxy-23,24-bisnorchol-4-ene-3-one from sterols in Mycobacterium neoaurum by increasing cell permeability and modifying multiple genes

(2017) Liang-Bin Xiong et al.   Microbial Cell Factories

Unraveling and engineering the production of 23,24-bisnorcholenic steroids in sterol metabolism

(2016) Li-Qin Xu et al.   Scientific Reports

3-Ketosteroid 9α-hydroxylase enzymes: Rieske non-heme monooxygenases essential for bacterial steroid degradation

(2014) Mirjan Petrusma et al.   ANTONIE VAN LEEUWENHOEK INTERNATIONAL JOURNAL OF GENERAL AND MOLECULAR MICROBIOLOGY

Characterization and engineering of 3-ketosteroid-△1-dehydrogenase and 3-ketosteroid-9α-hydroxylase in Mycobacterium neoaurum ATCC 25795 to produce 9α-hydroxy-4-androstene-3,17-dione through the catabolism of sterols

(2014) Kang Yao et al.   METABOLIC ENGINEERING

Microbial steroid transformations: current state and prospects

(2012) Marina V. Donova et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Catabolism and biotechnological applications of cholesterol degrading bacteria

(2012) J. L. García et al.   Microbial Biotechnology

Multiplicity of 3-Ketosteroid-9 -Hydroxylase Enzymes in Rhodococcus rhodochrous DSM43269 for Specific Degradation of Different Classes of Steroids

(2011) M. Petrusma et al.   JOURNAL OF BACTERIOLOGY

Characterization of 3-Ketosteroid 9α-Hydroxylase, a Rieske Oxygenase in the Cholesterol Degradation Pathway ofMycobacterium tuberculosis

(2009) Jenna K. Capyk et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

3-Ketosteroid 9α-hydroxylase is an essential factor in the pathogenesis ofMycobacterium tuberculosis

(2009) Yanmin Hu et al.   MOLECULAR MICROBIOLOGY