A Dual Role Reductase from Phytosterols Catabolism Enables the Efficient Production of Valuable Steroid Precursors
出版年份 2020 全文链接
标题
A Dual Role Reductase from Phytosterols Catabolism Enables the Efficient Production of Valuable Steroid Precursors
作者
关键词
-
出版物
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
Volume -, Issue -, Pages -
出版商
Wiley
发表日期
2020-12-01
DOI
10.1002/anie.202015462
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Enhancing the bioconversion of phytosterols to steroidal intermediates by the deficiency of kasB in the cell wall synthesis of Mycobacterium neoaurum
- (2020) Liang-Bin Xiong et al. Microbial Cell Factories
- The steroid side-chain–cleaving aldolase Ltp2–ChsH2DUF35 is a thiolase superfamily member with a radically repurposed active site
- (2019) Rebecca Aggett et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Characterization and engineering control of the effects of reactive oxygen species on the conversion of sterols to steroid synthons in Mycobacterium neoaurum
- (2019) Wan-Ju Sun et al. METABOLIC ENGINEERING
- New product identification in the sterol metabolism by an industrial strain Mycobacterium neoaurum NRRL B-3805
- (2018) Xuemei Li et al. STEROIDS
- Improving the production of 22-hydroxy-23,24-bisnorchol-4-ene-3-one from sterols in Mycobacterium neoaurum by increasing cell permeability and modifying multiple genes
- (2017) Liang-Bin Xiong et al. Microbial Cell Factories
- Microbial production of fatty alcohols
- (2016) Sandy Fillet et al. WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY
- Unraveling and engineering the production of 23,24-bisnorcholenic steroids in sterol metabolism
- (2016) Li-Qin Xu et al. Scientific Reports
- Comprehensive Structural and Biochemical Analysis of the Terminal Myxalamid Reductase Domain for the Engineered Production of Primary Alcohols
- (2015) Jesus F. Barajas et al. CHEMISTRY & BIOLOGY
- Leaderless Transcripts and Small Proteins Are Common Features of the Mycobacterial Translational Landscape
- (2015) Scarlet S. Shell et al. PLoS Genetics
- Unraveling Cholesterol Catabolism in Mycobacterium tuberculosis: ChsE4-ChsE5 α2β2 Acyl-CoA Dehydrogenase Initiates β-Oxidation of 3-Oxo-cholest-4-en-26-oyl CoA
- (2015) Meng Yang et al. ACS Infectious Diseases
- A Distinct MaoC-like Enoyl-CoA Hydratase Architecture Mediates Cholesterol Catabolism in Mycobacterium tuberculosis
- (2014) Meng Yang et al. ACS Chemical Biology
- A Concise Account of Various Approaches for Stereoselective Construction of the C-20(H) Stereogenic Center in Steroid Side Chain
- (2014) Bapurao B. Shingate et al. CHEMICAL REVIEWS
- Characterization and engineering of 3-ketosteroid-△1-dehydrogenase and 3-ketosteroid-9α-hydroxylase in Mycobacterium neoaurum ATCC 25795 to produce 9α-hydroxy-4-androstene-3,17-dione through the catabolism of sterols
- (2014) Kang Yao et al. METABOLIC ENGINEERING
- Comparative analysis of genes encoding key steroid core oxidation enzymes in fast-growing Mycobacterium spp. strains
- (2013) E.Yu. Bragin et al. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY
- Genome-wide Mapping of Transcriptional Start Sites Defines an Extensive Leaderless Transcriptome in Mycobacterium tuberculosis
- (2013) Teresa Cortes et al. Cell Reports
- Microbial steroid transformations: current state and prospects
- (2012) Marina V. Donova et al. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
- Identification and engineering of cholesterol oxidases involved in the initial step of sterols catabolism in Mycobacterium neoaurum
- (2012) Kang Yao et al. METABOLIC ENGINEERING
- FadD19 of Rhodococcus rhodochrous DSM43269, a Steroid-Coenzyme A Ligase Essential for Degradation of C-24 Branched Sterol Side Chains
- (2011) M. H. Wilbrink et al. APPLIED AND ENVIRONMENTAL MICROBIOLOGY
- Characterization of a Fatty Acyl-CoA Reductase fromMarinobacter aquaeoleiVT8: A Bacterial Enzyme Catalyzing the Reduction of Fatty Acyl-CoA to Fatty Alcohol
- (2011) Robert M. Willis et al. BIOCHEMISTRY
- A prokaryotic acyl-CoA reductase performing reduction of fatty acyl-CoA to fatty alcohol
- (2011) Per Hofvander et al. FEBS LETTERS
- Pathway Profiling inMycobacterium tuberculosis
- (2011) Suzanne T. Thomas et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Activity of 3-Ketosteroid 9α-Hydroxylase (KshAB) Indicates Cholesterol Side Chain and Ring Degradation Occur Simultaneously inMycobacterium tuberculosis
- (2011) Jenna K. Capyk et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Inactivation and Augmentation of the Primary 3-Ketosteroid- 1- Dehydrogenase in Mycobacterium neoaurum NwIB-01: Biotransformation of Soybean Phytosterols to 4-Androstene- 3,17-Dione or 1,4-Androstadiene-3,17-Dione
- (2010) W. Wei et al. APPLIED AND ENVIRONMENTAL MICROBIOLOGY
- Structural and Biochemical Characterization ofMycobacterium tuberculosisCYP142
- (2010) Max D. Driscoll et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Rhodococcus rhodochrous DSM 43269 3-Ketosteroid 9 -Hydroxylase, a Two-Component Iron-Sulfur-Containing Monooxygenase with Subtle Steroid Substrate Specificity
- (2009) M. Petrusma et al. APPLIED AND ENVIRONMENTAL MICROBIOLOGY
- Purification, Characterization, and Potential Bacterial Wax Production Role of an NADPH-Dependent Fatty Aldehyde Reductase from Marinobacter aquaeolei VT8
- (2009) B. D. Wahlen et al. APPLIED AND ENVIRONMENTAL MICROBIOLOGY
- A Thiolase of Mycobacterium tuberculosis Is Required for Virulence and Production of Androstenedione and Androstadienedione from Cholesterol
- (2009) N. M. Nesbitt et al. INFECTION AND IMMUNITY
- Mycobacterial Cytochrome P450 125 (Cyp125) Catalyzes the Terminal Hydroxylation of C27 Steroids
- (2009) Jenna K. Capyk et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Cytochrome P450â125 (CYP125) catalyses C26-hydroxylation to initiate sterol side-chain degradation inRhodococcus jostiiRHA1
- (2009) Kamila Z. RosÅoniec et al. MOLECULAR MICROBIOLOGY
- Isolation, Biological Significance, Synthesis, and Cytotoxic Evaluation of New Natural Parathiosteroids A−C and Analogues from the Soft CoralParagorgiasp.
- (2008) Javier Jesús Poza et al. JOURNAL OF ORGANIC CHEMISTRY
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started