Environmental chemicals-induced ROS generation and immunotoxicity: A comprehensive review

Polychlorinated Biphenyl Quinone Metabolites Cause Neutrophil Extracellular Traps in Mouse Bone Marrow Neutrophils

(2022) Lu Peng et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Lithium intoxication induced pyroptosis via ROS / NF‐κB / NLRP3 inflammasome regulatory networks in kidney of mice

(2022) Hongyuan Jing et al.   ENVIRONMENTAL TOXICOLOGY

Hsp70 overexpression in Drosophila hemocytes attenuates benzene‐induced immune and developmental toxicity via regulating ROS/JNK signaling pathway

(2022) Leonard Clinton D'Souza et al.   ENVIRONMENTAL TOXICOLOGY

Astilbin attenuates apoptosis induced by cadmium through oxidative stress in carp (Cyprinus carpio L.) head kidney lymphocyte

(2022) Haoran Zhang et al.   FISH & SHELLFISH IMMUNOLOGY

Silica nanoparticles induce pyroptosis and cardiac hypertrophy via ROS/NLRP3/Caspase-1 pathway

(2022) Fenghong Wang et al.   FREE RADICAL BIOLOGY AND MEDICINE

Differences in sensitivity of human lymphocytes and fish lymphocytes to polyvinyl chloride microplastic toxicity

(2022) Ahmad Salimi et al.   TOXICOLOGY AND INDUSTRIAL HEALTH

Ambient ozone exposure induces ROS related-mitophagy and pyroptosis via NLRP3 inflammasome activation in rat lung cells

(2022) Lei Tian et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

MITO–MANAGING ROS & REDOX TO REBOOT THE IMMUNE SYSTEM Tapping Mitochondria & Redox Management to Extend the Reach of Hematopoietic Stem Cell Transplantation

(2021) Mary Mohrin   FREE RADICAL BIOLOGY AND MEDICINE

Interplay between neutrino and gravity portals for FIMP dark matter

(2021) Marco Chianese et al.   JOURNAL OF COSMOLOGY AND ASTROPARTICLE PHYSICS

Immunotoxicology of cadmium: Cells of the immune system as targets and effectors of cadmium toxicity

(2021) Ivana Mirkov et al.   FOOD AND CHEMICAL TOXICOLOGY

COVID-19: captures iron and generates reactive oxygen species to damage the human immune system

(2021) Liu Wenzhong et al.   AUTOIMMUNITY

Toxic Mechanisms of Five Heavy Metals: Mercury, Lead, Chromium, Cadmium, and Arsenic

(2021) Mahdi Balali-Mood et al.   Frontiers in Pharmacology

Spectrophotometric assays for evaluation of Reactive Oxygen Species (ROS) in serum: general concepts and applications in dogs and humans

(2021) Camila Peres Rubio et al.   BMC Veterinary Research

Huang et al. reply

(2021) Jun X. Huang et al.   NATURE METHODS

Effects of Cadmium Exposure on the Immune System and Immunoregulation

(2021) Zhineng Wang et al.   Frontiers in Immunology

Hexavalent chromium inhibits the formation of neutrophil extracellular traps and promotes the apoptosis of neutrophils via AMPK signaling pathway

(2021) Yu Ma et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Lead impaired immune function and tissue integrity in yellow catfish (Peltobargus fulvidraco) by mediating oxidative stress, inflammatory response and apoptosis

(2021) Jie Guo et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Immunotoxicity of polychlorinated biphenyls (PCBs) to the marine crustacean species, Scylla paramamosain

(2021) Chongyang Xiao et al.   ENVIRONMENTAL POLLUTION

Impact of phthalates and bisphenols plasticizers on haemocyte immune function of aquatic invertebrates: A review on physiological, biochemical, and genomic aspects

(2021) Mario Alberto Burgos-Aceves et al.   JOURNAL OF HAZARDOUS MATERIALS

Multi-walled carbon nanotubes trigger lysosome-dependent cell death (pyroptosis) in macrophages but not in neutrophils

(2021) Sandeep Keshavan et al.   Nanotoxicology

Graphene oxide nanoparticles induce hepatic dysfunction through the regulation of innate immune signaling in zebrafish (Danio rerio)

(2020) Guanghua Xiong et al.   Nanotoxicology

Epimedium polysaccharides attenuates hematotoxicity by reducing oxidative stress and enhancing immune function in mice model of benzene-induced bone marrow failure

(2020) Jin He et al.   BIOMEDICINE & PHARMACOTHERAPY

Reactive oxygen species (ROS) as pleiotropic physiological signalling agents

(2020) Helmut Sies et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Reactive Oxygen Species-Related Nanoparticle Toxicity in the Biomedical Field

(2020) Zhongjie Yu et al.   Nanoscale Research Letters

Pb exposure triggers MAPK-dependent inflammation by activating oxidative stress and miRNA-155 expression in carp head kidney

(2020) Hongyuan Jing et al.   FISH & SHELLFISH IMMUNOLOGY

Arsenic exposure associated T cell proliferation, smoking, and vitamin D in Bangladeshi men and women

(2020) Scott W. Burchiel et al.   PLoS One

Micro- and nano-plastics activation of oxidative and inflammatory adverse outcome pathways

(2020) Moyan Hu et al.   Redox Biology

Adverse effects of pesticides on the functions of immune system

(2020) Gun-Hwi Lee et al.   COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY

Immunotoxicities of microplastics and sertraline, alone and in combination, to a bivalve species: size-dependent interaction and potential toxication mechanism

(2020) Wei Shi et al.   JOURNAL OF HAZARDOUS MATERIALS

Foetal exposure to heavy metals and risk of atopic diseases in early childhood.

(2020) Giancarlo Pesce et al.   PEDIATRIC ALLERGY AND IMMUNOLOGY

Innate-adaptive immunity interplay and redox regulation in immune response

(2020) Lizhe Sun et al.   Redox Biology

COVID-19 and Oxidative Stress

(2020) B. V. Chernyak et al.   BIOCHEMISTRY-MOSCOW

Heavy metal associated health hazards: An interplay of oxidative stress and signal transduction

(2020) Jagdish Gopal Paithankar et al.   CHEMOSPHERE

Antagonistic effect of N-acetyl-L-cysteine against cadmium-induced cytotoxicity and abnormal immune response on chicken peritoneal macrophages

(2020) Ding Zhang et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Mitochondrial reactive oxygen species enable proinflammatory signaling through disulfide linkage of NEMO

(2019) Marc Herb et al.   Science Signaling

The effect of N-acetylcysteine supplementation on the oxidative stress levels, apoptosis, DNA damage, and hematopoietic effect in pesticide-exposed fish blood

(2019) Arzu Ucar et al.   JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY

Exposure routes and health effects of heavy metals on children

(2019) Muwaffak Al osman et al.   BIOMETALS

Toxic effects of lead exposure on bioaccumulation, oxidative stress, neurotoxicity, and immune responses in fish: A review

(2019) Ju-Wook Lee et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

Multi-walled carbon nanotubes (MWCNTs) promoted lipid accumulation in THP-1 macrophages through modulation of endoplasmic reticulum (ER) stress

(2019) Jimin Long et al.   Nanotoxicology

The relative impact of toxic heavy metals (THMs) (arsenic (As), cadmium (Cd), chromium (Cr)(VI), mercury (Hg), and lead (Pb)) on the total environment: an overview

(2019) Zeeshanur Rahman et al.   ENVIRONMENTAL MONITORING AND ASSESSMENT

Altered Gene Expression in Dioxin-Like and Non-Dioxin-Like PCB Exposed Peripheral Blood Mononuclear Cells

(2019) Marike M. Leijs et al.   International Journal of Environmental Research and Public Health

Dibutyl phthalate-mediated oxidative stress induces splenic injury in mice and the attenuating effects of vitamin E and curcumin

(2019) Xianliang Wang et al.   FOOD AND CHEMICAL TOXICOLOGY

Astilbin protects chicken peripheral blood lymphocytes from cadmium-induced necroptosis via oxidative stress and the PI3K/Akt pathway

(2019) Chi Xin et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Prenatal and postnatal cadmium exposure and cellular immune responses among pre-school children

(2019) Qiang Zeng et al.   ENVIRONMENT INTERNATIONAL

Immunotoxicity of microplastics and two persistent organic pollutants alone or in combination to a bivalve species

(2019) Yu Tang et al.   ENVIRONMENTAL POLLUTION

Immunotoxicity of bisphenol S and F are similar to that of bisphenol A during zebrafish early development

(2018) Wenhui Qiu et al.   CHEMOSPHERE

Occupational exposure to pesticides in family agriculture and the oxidative, biochemical and hematological profile in this agricultural model

(2018) Márcia Denise Pavanelo Cattelan et al.   LIFE SCIENCES

Real time monitoring and quantification of reactive oxygen species in breast cancer cell line MCF-7 by 2′,7′–dichlorofluorescin diacetate (DCFDA) assay

(2018) Daniela Figueroa et al.   JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS

The impact of ocean acidification and cadmium on the immune responses of Pacific oyster, Crassostrea gigas

(2018) Ruiwen Cao et al.   FISH & SHELLFISH IMMUNOLOGY

Identification of a functional antioxidant response element at the HIF1A locus

(2018) Sarah E. Lacher et al.   Redox Biology

Immunotoxicity of titanium dioxide nanoparticles via simultaneous induction of apoptosis and multiple toll-like receptors signaling through ROS-dependent SAPK/JNK and p38 MAPK activation

(2018) Madhusmita Dhupal et al.   International Journal of Nanomedicine

Overexpression of HIF-1a could partially protect K562 cells from 1,4-benzoquinone induced toxicity by inhibiting ROS, apoptosis and enhancing glycolysis

(2018) Rongli Sun et al.   TOXICOLOGY IN VITRO

Circulatory heavy metals (cadmium, lead, mercury, and chromium) inversely correlate with plasma GST activity and GSH level in COPD patients and impair NOX4/Nrf2/GCLC/GST signaling pathway in cultured monocytes

(2018) Kabita Gogoi et al.   TOXICOLOGY IN VITRO

Imbalanced immune responses involving inflammatory molecules and immune-related pathways in the lung of acute and subchronic arsenic-exposed mice

(2017) Jinlong Li et al.   ENVIRONMENTAL RESEARCH

Assessment of arsenic trioxide in the heart of Gallus gallus: alterations of oxidative damage parameters, inflammatory cytokines, and cardiac enzymes

(2017) Si-Wen Li et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

Chlorpyrifos exposure in common carp (Cyprinus carpio L.) leads to oxidative stress and immune responses

(2017) Ziwei Zhang et al.   FISH & SHELLFISH IMMUNOLOGY

Reactive Oxygen Species Localization Programs Inflammation to Clear Microbes of Different Size

(2017) Annika Warnatsch et al.   IMMUNITY

Iron oxide nanoparticles induced cytotoxicity, oxidative stress and DNA damage in lymphocytes

(2017) Usha Singh Gaharwar et al.   JOURNAL OF APPLIED TOXICOLOGY

Signatures of extra dimensions in gravitational waves

(2017) David Andriot et al.   JOURNAL OF COSMOLOGY AND ASTROPARTICLE PHYSICS

Power spectra based Planck constraints on compensated isocurvature, and forecasts for LiteBIRD and CORE space missions

(2017) Jussi Väliviita   JOURNAL OF COSMOLOGY AND ASTROPARTICLE PHYSICS

Cadmium triggers mitochondrial oxidative stress in human peripheral blood lymphocytes and monocytes: Analysis using in vitro and system toxicology approaches

(2017) Nouf Abdulkareem Omer Alkharashi et al.   JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY

Immunological effects of occupational exposure to lead

(2017) Concettina Fenga et al.   Molecular Medicine Reports

Murder most foul

(2017) Veronika Meduna   NEW SCIENTIST

Pathways that Regulate ROS Scavenging Enzymes, and Their Role in Defense Against Tissue Destruction in Periodontitis

(2017) Hiroyuki Kanzaki et al.   Frontiers in Physiology

Immune-associated parameters and antioxidative responses to cadmium in the freshwater crab Sinopotamon henanense

(2016) Yanying Zhou et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Oxidative stress and immune disturbance after long-term exposure to bisphenol A in juvenile common carp (Cyprinus carpio)

(2016) Wenhui Qiu et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Elevated blood lead and cadmium levels associated with chronic infections among non-smokers in a cross-sectional analysis of NHANES data

(2016) Whitney S. Krueger et al.   Environmental Health

Effects of combined exposure to formaldehyde and benzene on immune cells in the blood and spleen in Balb/c mice

(2016) Huaxiao Wen et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

Involvement of hypoxia-inducible factor-1 α (HIF-1α) in inhibition of benzene on mouse hematopoietic system

(2016) Xing Meng et al.   JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES

Mitochondrial respiratory-chain adaptations in macrophages contribute to antibacterial host defense

(2016) Johan Garaude et al.   NATURE IMMUNOLOGY

Exposure of children to arsenic in drinking water in the Tharparkar region of Sindh, Pakistan

(2016) Kapil Dev Brahman et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Current understanding of interactions between nanoparticles and the immune system

(2016) Marina A. Dobrovolskaia et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Immunotoxicity assessment of CdSe/ZnS quantum dots in macrophages, lymphocytes and BALB/c mice

(2016) Xiaomei Wang et al.   JOURNAL OF NANOBIOTECHNOLOGY

Environmental and occupational exposure to cadmium in Iran: a systematic review

(2016) Leila Tavakkoli et al.   REVIEWS ON ENVIRONMENTAL HEALTH

Cadmium Induced Apoptosis in MG63 Cells by Increasing ROS, Activation of p38 MAPK and Inhibition of ERK 1/2 Pathways

(2015) Kong-He Hu et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Essential role of mitochondrial energy metabolism in Foxp3+ T-regulatory cell function and allograft survival

(2015) Ulf H. Beier et al.   FASEB JOURNAL

The toxicity of chlorpyrifos on the early life stage of zebrafish: A survey on the endpoints at development, locomotor behavior, oxidative stress and immunotoxicity

(2015) Yuanxiang Jin et al.   FISH & SHELLFISH IMMUNOLOGY

Silver nanoparticles rapidly induce atypical human neutrophil cell death by a process involving inflammatory caspases and reactive oxygen species and induce neutrophil extracellular traps release upon cell adhesion

(2015) Rafael Liz et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Consistent cosmic microwave background spectra from quantum depletion

(2015) Roberto Casadio et al.   JOURNAL OF COSMOLOGY AND ASTROPARTICLE PHYSICS

Distance priors from Planck 2015 data

(2015) Qing-Guo Huang et al.   JOURNAL OF COSMOLOGY AND ASTROPARTICLE PHYSICS

Roles of ROS mediated oxidative stress and DNA damage in 3-methyl-2-quinoxalin benzenevinylketo-1, 4-dioxide-induced immunotoxicity of Sprague–Dawley rats

(2015) Hui Gao et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Carbendazim has the potential to induce oxidative stress, apoptosis, immunotoxicity and endocrine disruption during zebrafish larvae development

(2015) Jinhua Jiang et al.   TOXICOLOGY IN VITRO

Cytotoxicity and cellular mechanisms involved in the toxicity of CdS quantum dots in hemocytes and gill cells of the mussel Mytilus galloprovincialis

(2014) A. Katsumiti et al.   AQUATIC TOXICOLOGY

Effects of avermectin on immune function and oxidative stress in the pigeon spleen

(2014) Ci Liu et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Antioxidant and anti-inflammatory effects of N-acetylcysteine against malathion-induced liver damages and immunotoxicity in rats

(2014) Mohamed Montassar Lasram et al.   LIFE SCIENCES

Silver nanoparticle-induced oxidative stress-dependent toxicity in Sprague-Dawley rats

(2014) Anita K. Patlolla et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Acute exposure to ZnO nanoparticles induces autophagic immune cell death

(2014) Brandon M. Johnson et al.   Nanotoxicology

Regulation of PKM2 and Nrf2-ARE Pathway during Benzoquinone Induced Oxidative Stress in Yolk Sac Hematopoietic Stem Cells

(2014) Jie Zhu et al.   PLoS One

Immunosuppression and oxidative stress induced by subchronic exposure to carbosulfan in rat spleen: immunomodulatory and antioxidant role of N-acetylcysteine

(2014) Ines Bini Dhouib et al.   TOXICOLOGY MECHANISMS AND METHODS

Role of Nrf2 in Oxidative Stress and Toxicity

(2013) Qiang Ma   Annual Review of Pharmacology and Toxicology

Phenolic metabolites of benzene induced caspase-dependent cytotoxicities to K562 cells accompanied with decrease in cell surface sialic acids

(2013) Yan Wang et al.   ENVIRONMENTAL TOXICOLOGY

Treatment with garlic restores membrane thiol content and ameliorates lead induced early death of erythrocytes in mice

(2013) Avik Sarkar et al.   ENVIRONMENTAL TOXICOLOGY

Gamma rays from top-mediated dark matter annihilations

(2013) C.B Jackson et al.   JOURNAL OF COSMOLOGY AND ASTROPARTICLE PHYSICS

Mitochondrial Reactive Oxygen Species Induces NLRP3-Dependent Lysosomal Damage and Inflammasome Activation

(2013) M. E. Heid et al.   JOURNAL OF IMMUNOLOGY

Intracellular Reactive Oxygen Species Mark and Influence the Megakaryocyte-Erythrocyte Progenitor Fate of Common Myeloid Progenitors

(2013) Akihito Shinohara et al.   STEM CELLS

Copper induced immunotoxicity promote differential apoptotic pathways in spleen and thymus

(2013) Soham Mitra et al.   TOXICOLOGY

SIRT3 Reverses Aging-Associated Degeneration

(2013) Katharine Brown et al.   Cell Reports

Reactive oxygen species (ROS) homeostasis and redox regulation in cellular signaling

(2012) Paul D. Ray et al.   CELLULAR SIGNALLING

Anti-tumour strategies aiming to target tumour-associated macrophages

(2012) Xiaoqiang Tang et al.   IMMUNOLOGY

Sirtuin 1 Is a Key Regulator of the Interleukin-12 p70/Interleukin-23 Balance in Human Dendritic Cells

(2012) Yolanda Alvarez et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Metal nanoparticle-induced micronuclei and oxidative DNA damage in mice

(2012) Ming-Fen Song et al.   JOURNAL OF CLINICAL BIOCHEMISTRY AND NUTRITION

Three Novel Acetylation Sites in the Foxp3 Transcription Factor Regulate the Suppressive Activity of Regulatory T Cells

(2012) H.-S. Kwon et al.   JOURNAL OF IMMUNOLOGY

Assessment of Immunotoxicity Parameters in Individuals Occupationally Exposed to Lead

(2012) Julia García-Lestón et al.   JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES

Leukemia-related chromosomal loss detected in hematopoietic progenitor cells of benzene-exposed workers

(2012) L Zhang et al.   LEUKEMIA

Cadmium-induced teratogenicity: Association with ROS-mediated endoplasmic reticulum stress in placenta

(2012) Zhen Wang et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Leukemia and Benzene

(2012) Robert Snyder   International Journal of Environmental Research and Public Health

Reactive oxygen species: Are they important for haematopoiesis?

(2011) José L. Sardina et al.   CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY

Non-linear mode coupling and the growth of perturbations in ΛCDM

(2011) Kari Enqvist et al.   JOURNAL OF COSMOLOGY AND ASTROPARTICLE PHYSICS

Exposure to benzene induces oxidative stress, alters the immune response and expression of p53 in gasoline filling workers

(2010) Nazia Uzma et al.   AMERICAN JOURNAL OF INDUSTRIAL MEDICINE

Subacute toxicity of p,p′-DDT on rat thyroid: Hormonal and histopathological changes

(2010) Olfa Tebourbi et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

Reactive oxygen species in cancer

(2010) Geou-Yarh Liou et al.   FREE RADICAL RESEARCH

Measuring dark energy spatial inhomogeneity with supernova data

(2010) Asantha Cooray et al.   JOURNAL OF COSMOLOGY AND ASTROPARTICLE PHYSICS

In utero and in vitro effects of benzene and its metabolites on erythroid differentiation and the role of reactive oxygen species

(2010) Helen J. Badham et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

The Role of Oxidative Stress in Carcinogenesis Induced by Metals and Xenobiotics

(2010) Frank Henkler et al.   Cancers

SIRT1 inhibits inflammatory pathways in macrophages and modulates insulin sensitivity

(2009) Takeshi Yoshizaki et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

NF-E2 domination over Nrf2 promotes ROS accumulation and megakaryocytic maturation

(2009) H. Motohashi et al.   BLOOD

Benzene-induced bone-marrow toxicity: A hematopoietic stem-cell-specific, aryl hydrocarbon receptor-mediated adverse effect

(2009) Yoko Hirabayashi et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Preface

(2009) Michael G. Bird et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Oxidative stress and immunotoxic effects of lead and their amelioration with myrrh (Commiphora molmol) emulsion

(2009) Khaled M. Ashry et al.   FOOD AND CHEMICAL TOXICOLOGY

The type III histone deacetylase Sirt1 is essential for maintenance of T cell tolerance in mice

(2009) Jinping Zhang et al.   JOURNAL OF CLINICAL INVESTIGATION

Cytotoxicity and Genotoxicity of Silver Nanoparticles in Human Cells

(2008) P. V. AshaRani et al.   ACS Nano

NADPH oxidase controls phagosomal pH and antigen cross-presentation in human dendritic cells

(2008) A. R. Mantegazza et al.   BLOOD

In vitro models for the assessment of inflammatory and immuno-modulatory effects of the volatile organic compound chlorobenzene

(2008) Irina Lehmann et al.   EXPERIMENTAL AND TOXICOLOGIC PATHOLOGY