标题
Improving the Tuberculosis Drug Development Pipeline
作者
关键词
-
出版物
Chemical Biology & Drug Design
Volume 86, Issue 5, Pages 951-960
出版商
Wiley
发表日期
2015-03-16
DOI
10.1111/cbdd.12549
参考文献
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注意：仅列出部分参考文献，下载原文获取全部文献信息。- Stress and Host Immunity Amplify Mycobacterium tuberculosis Phenotypic Heterogeneity and Induce Nongrowing Metabolically Active Forms
- (2015) Giulia Manina et al. Cell Host & Microbe
- TheIn VivoEnvironment Accelerates Generation of Resuscitation-Promoting Factor–Dependent Mycobacteria
- (2014) Obolbek Turapov et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- The Molecular Bacterial Load Assay Replaces Solid Culture for Measuring Early Bactericidal Response to Antituberculosis Treatment
- (2014) I. Honeyborne et al. JOURNAL OF CLINICAL MICROBIOLOGY
- Advancing the portfolio of tuberculosis diagnostics, drugs, biomarkers, and vaccines
- (2014) Alimuddin I Zumla et al. LANCET INFECTIOUS DISEASES
- New antituberculosis drugs, regimens, and adjunct therapies: needs, advances, and future prospects
- (2014) Alimuddin I Zumla et al. LANCET INFECTIOUS DISEASES
- The path of anti-tuberculosis drugs: from blood to lesions to mycobacterial cells
- (2014) Véronique Dartois NATURE REVIEWS MICROBIOLOGY
- Four-Month Moxifloxacin-Based Regimens for Drug-Sensitive Tuberculosis
- (2014) Stephen H. Gillespie et al. NEW ENGLAND JOURNAL OF MEDICINE
- High-Dose Rifapentine with Moxifloxacin for Pulmonary Tuberculosis
- (2014) Amina Jindani et al. NEW ENGLAND JOURNAL OF MEDICINE
- A high-resolution network model for global gene regulation in Mycobacterium tuberculosis
- (2014) Eliza J.R. Peterson et al. NUCLEIC ACIDS RESEARCH
- Delayed bactericidal response of Mycobacterium tuberculosis to bedaquiline involves remodelling of bacterial metabolism
- (2014) Anil Koul et al. Nature Communications
- Radiologic Responses in Cynomolgus Macaques for Assessing Tuberculosis Chemotherapy Regimens
- (2013) Philana Ling Lin et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Microbial Persistence and the Road to Drug Resistance
- (2013) Nadia R. Cohen et al. Cell Host & Microbe
- Rapid in vivo assessment of drug efficacy against Mycobacterium tuberculosis using an improved firefly luciferase
- (2013) Nuria Andreu et al. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
- Direct Comparison of Xpert MTB/RIF Assay with Liquid and Solid Mycobacterial Culture for Quantification of Early Bactericidal Activity
- (2013) X. A. Kayigire et al. JOURNAL OF CLINICAL MICROBIOLOGY
- Tuberculosis biomarkers discovery: developments, needs, and challenges
- (2013) Robert S Wallis et al. LANCET INFECTIOUS DISEASES
- The Mycobacterium tuberculosis regulatory network and hypoxia
- (2013) James E. Galagan et al. NATURE
- Discovery of Q203, a potent clinical candidate for the treatment of tuberculosis
- (2013) Kevin Pethe et al. NATURE MEDICINE
- Advances in the development of new tuberculosis drugs and treatment regimens
- (2013) Alimuddin Zumla et al. NATURE REVIEWS DRUG DISCOVERY
- A Humanized Mouse Model of Tuberculosis
- (2013) Veronica E. Calderon et al. PLoS One
- Transcriptional Blood Signatures Distinguish Pulmonary Tuberculosis, Pulmonary Sarcoidosis, Pneumonias and Lung Cancers
- (2013) Chloe I. Bloom et al. PLoS One
- Exploring the Mode of Action of Bioactive Compounds by Microfluidic Transcriptional Profiling in Mycobacteria
- (2013) Paul Murima et al. PLoS One
- Dynamic Persistence of Antibiotic-Stressed Mycobacteria
- (2013) Y. Wakamoto et al. SCIENCE
- Antitubercular specific activity of ibuprofen and the other 2-arylpropanoic acids using the HT-SPOTi whole-cell phenotypic assay
- (2013) Juan D Guzman et al. BMJ Open
- A computational pipeline for quantification of pulmonary infections in small animal models using serial PET-CT imaging
- (2013) Ulas Bagci et al. EJNMMI Research
- Dose-Ranging Comparison of Rifampin and Rifapentine in Two Pathologically Distinct Murine Models of Tuberculosis
- (2012) Ian M. Rosenthal et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Why thioridazine in combination with antibiotics cures extensively drug-resistant Mycobacterium tuberculosis infections
- (2012) Leonard Amaral et al. INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS
- The chemotherapy of tuberculosis: past, present and future [State of the art]
- (2012) D. Mitchison et al. INTERNATIONAL JOURNAL OF TUBERCULOSIS AND LUNG DISEASE
- Is repositioning of drugs a viable alternative in the treatment of tuberculosis?
- (2012) J. C. Palomino et al. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
- Synthesis and Biological Evaluation of Purpurealidin E-Derived Marine Sponge Metabolites: Aplysamine-2, Aplyzanzine A, and Suberedamines A and B
- (2012) Suresh K. Kottakota et al. JOURNAL OF NATURAL PRODUCTS
- Versatile Routes to Marine Sponge Metabolites through Benzylidene Rhodanines
- (2012) Suresh K. Kottakota et al. ORGANIC LETTERS
- Antimycobacterials from Lovage Root (Ligusticum officinaleKoch)
- (2012) Juan David Guzman et al. PHYTOTHERAPY RESEARCH
- Detectable Changes in The Blood Transcriptome Are Present after Two Weeks of Antituberculosis Therapy
- (2012) Chloe I. Bloom et al. PLoS One
- Modeling early bactericidal activity in murine tuberculosis provides insights into the activity of isoniazid and pyrazinamide
- (2012) J. Grosset et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Nonsteroidal anti-inflammatory drug sensitizes Mycobacterium tuberculosis to endogenous and exogenous antimicrobials
- (2012) B. Gold et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- MDR, XDR, TDR tuberculosis: ominous progression
- (2012) Zarir F Udwadia THORAX
- Why Do We Use 600 mg of Rifampicin in Tuberculosis Treatment?
- (2011) J. van Ingen et al. CLINICAL INFECTIOUS DISEASES
- An antibacterial from Hypericum acmosepalum inhibits ATP-dependent MurE ligase from Mycobacterium tuberculosis
- (2011) Khadijo Osman et al. INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS
- Interaction of N-methyl-2-alkenyl-4-quinolones with ATP-dependent MurE ligase of Mycobacterium tuberculosis: antibacterial activity, molecular docking and inhibition kinetics
- (2011) Juan David Guzman et al. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
- Molecular Bacterial Load Assay, a Culture-Free Biomarker for Rapid and Accurate Quantification of Sputum Mycobacterium tuberculosis Bacillary Load during Treatment
- (2011) Isobella Honeyborne et al. JOURNAL OF CLINICAL MICROBIOLOGY
- Characterization and Transcriptome Analysis of Mycobacterium tuberculosis Persisters
- (2011) I. Keren et al. mBio
- Comparative Studies Evaluating Mouse Models Used for Efficacy Testing of Experimental Drugs againstMycobacterium tuberculosis
- (2010) Mary A. De Groote et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Caseation of human tuberculosis granulomas correlates with elevated host lipid metabolism
- (2010) Mi-Jeong Kim et al. EMBO Molecular Medicine
- Thioridazine cures extensively drug-resistant tuberculosis (XDR-TB) and the need for global trials is now!
- (2010) Leonard Amaral et al. INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS
- Anti-tubercular screening of natural products from Colombian plants: 3-methoxynordomesticine, an inhibitor of MurE ligase of Mycobacterium tuberculosis
- (2010) J. D. Guzman et al. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
- Resuscitation-promoting Factors Reveal an Occult Population of Tubercle Bacilli in Sputum
- (2009) Galina V. Mukamolova et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Animal models of tuberculosis
- (2009) Douglas Young EUROPEAN JOURNAL OF IMMUNOLOGY
- Resuscitation-promoting factors as lytic enzymes for bacterial growth and signaling
- (2009) Bavesh Davandra Kana et al. FEMS IMMUNOLOGY AND MEDICAL MICROBIOLOGY
- The resuscitation-promoting factors ofMycobacterium tuberculosisare required for virulence and resuscitation from dormancy but are collectively dispensable for growthin vitro
- (2009) Bavesh D. Kana et al. MOLECULAR MICROBIOLOGY
- Foamy macrophages and the progression of the human tuberculosis granuloma
- (2009) David G Russell et al. NATURE IMMUNOLOGY
- A Novel In Vitro Multiple-Stress Dormancy Model for Mycobacterium tuberculosis Generates a Lipid-Loaded, Drug-Tolerant, Dormant Pathogen
- (2009) Chirajyoti Deb et al. PLoS One
- Arylamine N-Acetyltransferases in Mycobacteria
- (2008) Edith Sim et al. CURRENT DRUG METABOLISM
- Confronting the scientific obstacles to global control of tuberculosis
- (2008) Douglas B. Young et al. JOURNAL OF CLINICAL INVESTIGATION
- Bioactive Pyridine-N-oxide Disulfides fromAllium stipitatum¶
- (2008) Gemma O’Donnell et al. JOURNAL OF NATURAL PRODUCTS
- Innate immunity in tuberculosis: myths and truth
- (2008) Daniel S. Korbel et al. MICROBES AND INFECTION
- Mycobacterial persistence requires the utilization of host cholesterol
- (2008) A. K. Pandey et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Resuscitation-promoting factors are expressed in Mycobacterium tuberculosis-infected human tissue
- (2008) A.P. Davies et al. TUBERCULOSIS
- Cytological and Transcript Analyses Reveal Fat and Lazy Persister-Like Bacilli in Tuberculous Sputum
- (2008) Natalie J Garton et al. PLOS MEDICINE
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