Development of adsorptive hybrid filters to enable two-step purification of biologics

Advance chromatin extraction improves capture performance of protein A affinity chromatography

(2016) Rui Nian et al.   JOURNAL OF CHROMATOGRAPHY A

On the workings of laterally-fed membrane chromatography

(2016) Raja Ghosh et al.   JOURNAL OF MEMBRANE SCIENCE

Clarification technologies for monoclonal antibody manufacturing processes: Current state and future perspectives

(2015) Nripen Singh et al.   BIOTECHNOLOGY AND BIOENGINEERING

Development of robust antibody purification by optimizing protein-A chromatography in combination with precipitation methodologies

(2015) Srinivas Chollangi et al.   BIOTECHNOLOGY AND BIOENGINEERING

Mechanistic evaluation of virus clearance by depth filtration

(2015) Adith Venkiteshwaran et al.   BIOTECHNOLOGY PROGRESS

Protein A chromatography increases monoclonal antibody aggregation rate during subsequent low pH virus inactivation hold

(2015) Alice R. Mazzer et al.   JOURNAL OF CHROMATOGRAPHY A

Antibodies to watch in 2016

(2015) Janice M. Reichert   mAbs

Avoiding antibody aggregation during processing: Establishing hold times

(2014) Varsha Joshi et al.   Biotechnology Journal

Nonspecific interactions of chromatin with immunoglobulin G and protein A, and their impact on purification performance

(2014) Pete Gagnon et al.   JOURNAL OF CHROMATOGRAPHY A

Identification and characterization of host cell protein product-associated impurities in monoclonal antibody bioprocessing

(2013) Nicholas E. Levy et al.   BIOTECHNOLOGY AND BIOENGINEERING

Characterization and removal of aggregates formed by nonspecific interaction of IgM monoclonal antibodies with chromatin catabolites during cell culture production

(2013) Hui Theng Gan et al.   JOURNAL OF CHROMATOGRAPHY A

Host cell protein dynamics in recombinant CHO cells

(2013) Catherine EM Hogwood et al.   Bioengineered

Recent advances in technology supporting biopharmaceutical production from mammalian cells

(2012) M. Butler et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

The effect of protein a cycle number on the performance and lifetime of an anion exchange polishing step

(2012) Timothy Iskra et al.   BIOTECHNOLOGY AND BIOENGINEERING

The dynamics of the CHO host cell protein profile during clarification and protein A capture in a platform antibody purification process

(2012) Catherine E.M. Hogwood et al.   BIOTECHNOLOGY AND BIOENGINEERING

Studying host cell protein interactions with monoclonal antibodies using high throughput protein A chromatography

(2012) Vikram N. Sisodiya et al.   Biotechnology Journal

Host cell protein adsorption characteristics during protein a chromatography

(2012) Richard D. R. Tarrant et al.   BIOTECHNOLOGY PROGRESS

Host cell protein dynamics in the supernatant of a mAb producing CHO cell line

(2011) A.S. Tait et al.   BIOTECHNOLOGY AND BIOENGINEERING

Select host cell proteins coelute with monoclonal antibodies in protein a chromatography

(2011) Bartek Nogal et al.   BIOTECHNOLOGY PROGRESS

Virus Removal in Ceramic Depth Filters Based on Diatomaceous Earth

(2011) Benjamin Michen et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Therapeutic antibodies: Market considerations, disease targets and bioprocessing

(2011) John G. Elvin et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Exploration of overloaded cation exchange chromatography for monoclonal antibody purification

(2011) Hui F. Liu et al.   JOURNAL OF CHROMATOGRAPHY A

Advances in the production and downstream processing of antibodies

(2011) John H. Chon et al.   New Biotechnology

Removal of colloidal particles in ceramic depth filters based on diatomaceous earth

(2011) Benjamin Michen et al.   SEPARATION AND PURIFICATION TECHNOLOGY

Analysis of viral clearance unit operations for monoclonal antibodies

(2010) George Miesegaes et al.   BIOTECHNOLOGY AND BIOENGINEERING

Industrialization of mAb production technology: The bioprocessing industry at a crossroads

(2010) Brian Kelley   mAbs

Cell culture processes for monoclonal antibody production

(2010) Feng Li et al.   mAbs

Recent advances in large-scale production of monoclonal antibodies and related proteins

(2010) Abhinav A. Shukla et al.   TRENDS IN BIOTECHNOLOGY

Design of a filter train for precipitate removal in monoclonal antibody downstream processing

(2009) Sunitha Kandula et al.   BIOTECHNOLOGY AND APPLIED BIOCHEMISTRY

Understanding the mechanism of virus removal by Q sepharose fast flow chromatography during the purification of CHO-cell derived biotherapeutics

(2009) Daniel M. Strauss et al.   BIOTECHNOLOGY AND BIOENGINEERING

Design of salt-tolerant membrane adsorbers for viral clearance

(2009) William Riordan et al.   BIOTECHNOLOGY AND BIOENGINEERING

Profiling of host cell proteins by two-dimensional difference gel electrophoresis (2D-DIGE): Implications for downstream process development

(2009) Mi Jin et al.   BIOTECHNOLOGY AND BIOENGINEERING

Salt tolerant membrane adsorbers for robust impurity clearance

(2009) William T. Riordan et al.   BIOTECHNOLOGY PROGRESS

Viral clearance using disposable systems in monoclonal antibody commercial downstream processing

(2008) Joe X. Zhou et al.   BIOTECHNOLOGY AND BIOENGINEERING

Host cell protein clearance during protein a chromatography: Development of an improved column wash step

(2008) Abhinav A. Shukla et al.   BIOTECHNOLOGY PROGRESS

Upstream processes in antibody production: Evaluation of critical parameters

(2007) Era Jain et al.   BIOTECHNOLOGY ADVANCES