Host cell protein dynamics in recombinant CHO cells

Identification and quantification of host cell protein impurities in biotherapeutics using mass spectrometry

(2012) Matthew R. Schenauer et al.   ANALYTICAL BIOCHEMISTRY

Host cell protein quantification by fourier transform mid infrared spectroscopy (FT-MIR)

(2012) Florian Capito et al.   BIOTECHNOLOGY AND BIOENGINEERING

The dynamics of the CHO host cell protein profile during clarification and protein A capture in a platform antibody purification process

(2012) Catherine E.M. Hogwood et al.   BIOTECHNOLOGY AND BIOENGINEERING

State-of-the-art in downstream processing of monoclonal antibodies: Process trends in design and validation

(2012) P. A. Marichal-Gallardo et al.   BIOTECHNOLOGY PROGRESS

Host cell protein adsorption characteristics during protein a chromatography

(2012) Richard D. R. Tarrant et al.   BIOTECHNOLOGY PROGRESS

Fishing human monoclonal antibodies from a CHO cell supernatant with boronic acid magnetic particles

(2012) L. Borlido et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Full automation and validation of a flexible ELISA platform for host cell protein and protein A impurity detection in biopharmaceuticals

(2012) Guillaume Rey et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Of [hamsters] and men

(2012) Andres H. Gutiérrez et al.   Human Vaccines & Immunotherapeutics

Mammalian cell protein expression for biopharmaceutical production

(2011) Jianwei Zhu   BIOTECHNOLOGY ADVANCES

Transforming growth factor-β1 is constitutively secreted by chinese hamster ovary cells and is functional in human cells

(2011) Richard Beatson et al.   BIOTECHNOLOGY AND BIOENGINEERING

Host cell protein dynamics in the supernatant of a mAb producing CHO cell line

(2011) A.S. Tait et al.   BIOTECHNOLOGY AND BIOENGINEERING

Economic comparison of diagnostic antibody production in perfusion stirred tank and in hollow fiber bioreactor processes

(2011) Raisa Vermasvuori et al.   BIOTECHNOLOGY PROGRESS

Select host cell proteins coelute with monoclonal antibodies in protein a chromatography

(2011) Bartek Nogal et al.   BIOTECHNOLOGY PROGRESS

Separation science is the key to successful biopharmaceuticals

(2011) Georges Guiochon et al.   JOURNAL OF CHROMATOGRAPHY A

Antibody capture by mixed-mode chromatography: A comprehensive study from determination of optimal purification conditions to identification of contaminating host cell proteins

(2011) Jerome Pezzini et al.   JOURNAL OF CHROMATOGRAPHY A

Advances in the production and downstream processing of antibodies

(2011) John H. Chon et al.   New Biotechnology

Fragmentation of a highly purified monoclonal antibody attributed to residual CHO cell protease activity

(2010) Sharon X. Gao et al.   BIOTECHNOLOGY AND BIOENGINEERING

Ultra scale-down prediction using microwell technology of the industrial scale clarification characteristics by centrifugation of mammalian cell broths

(2009) A.S. Tait et al.   BIOTECHNOLOGY AND BIOENGINEERING

Degradation of an Fc-fusion recombinant protein by host cell proteases: Identification of a CHO cathepsin D protease

(2009) Flavie Robert et al.   BIOTECHNOLOGY AND BIOENGINEERING

Host cell proteins in biologics development: Identification, quantitation and risk assessment

(2009) Xing Wang et al.   BIOTECHNOLOGY AND BIOENGINEERING

Profiling of host cell proteins by two-dimensional difference gel electrophoresis (2D-DIGE): Implications for downstream process development

(2009) Mi Jin et al.   BIOTECHNOLOGY AND BIOENGINEERING

2-D DIGE to expedite downstream process development for human monoclonal antibody purification

(2009) Julita K. Grzeskowiak et al.   PROTEIN EXPRESSION AND PURIFICATION

Host cell protein clearance during protein a chromatography: Development of an improved column wash step

(2008) Abhinav A. Shukla et al.   BIOTECHNOLOGY PROGRESS

Proteomic Profiling of Secreted Proteins from CHO Cells Using Surface-Enhanced Laser Desorption Ionization Time-of-Flight Mass Spectrometry

(2007) N. Kumar et al.   BIOTECHNOLOGY PROGRESS