Molecular alterations in bone marrow mesenchymal stromal cells derived from acute myeloid leukemia patients

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The role of microenvironment and immunity in drug response in leukemia

(2016) Emyr Bakker et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Protective mitochondrial transfer from bone marrow stromal cells to acute myeloid leukemic cells during chemotherapy

(2016) R. Moschoi et al.   BLOOD

The Emerging Hallmarks of Cancer Metabolism

(2016) Natalya N. Pavlova et al.   Cell Metabolism

Targeted Nanoparticles for the Delivery of Novel Bioactive Molecules to Pancreatic Cancer Cells

(2016) Vanna Sanna et al.   JOURNAL OF MEDICINAL CHEMISTRY

Massive parallel RNA sequencing of highly purified mesenchymal elements in low-risk MDS reveals tissue-context-dependent activation of inflammatory programs

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Making sense of hematopoietic stem cell niches

(2015) P. E. Boulais et al.   BLOOD

The molecular signature of AML mesenchymal stromal cells reveals candidate genes related to the leukemogenic process

(2015) Renata Binato et al.   CANCER LETTERS

Microenvironmental Remodeling as a Parameter and Prognostic Factor of Heterogeneous Leukemogenesis in Acute Myelogenous Leukemia

(2015) Jin-A Kim et al.   CANCER RESEARCH

Altered mesenchymal niche cells impede generation of normal hematopoietic progenitor cells in leukemic bone marrow

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Functional inhibition of mesenchymal stromal cells in acute myeloid leukemia

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Genetic instability in the tumor microenvironment: a new look at an old neighbor

(2015) Antonio Palumbo et al.   Molecular Cancer

MEG3 long noncoding RNA regulates the TGF-β pathway genes through formation of RNA–DNA triplex structures

(2015) Tanmoy Mondal et al.   Nature Communications

Mesenchymal stromal cells derived from acute myeloid leukemia bone marrow exhibit aberrant cytogenetics and cytokine elaboration

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Decorin: A Growth Factor Antagonist for Tumor Growth Inhibition

(2015) Tero A. H. Järvinen et al.   Biomed Research International

Decorin Suppresses Prostate Tumor Growth through Inhibition of Epidermal Growth Factor and Androgen Receptor Pathways

(2015) Yunping Hu et al.   NEOPLASIA

Reciprocal leukemia-stroma VCAM-1/VLA-4-dependent activation of NF- B mediates chemoresistance

(2014) R. Jacamo et al.   BLOOD

Myelodysplastic Cells in Patients Reprogram Mesenchymal Stromal Cells to Establish a Transplantable Stem Cell Niche Disease Unit

(2014) Hind Medyouf et al.   Cell Stem Cell

The bone marrow niche for haematopoietic stem cells

(2014) Sean J. Morrison et al.   NATURE

Leukaemogenesis induced by an activating β-catenin mutation in osteoblasts

(2014) Aruna Kode et al.   NATURE

Whole-Genome Sequencing Identifies Genetic Variances in Culture-Expanded Human Mesenchymal Stem Cells

(2014) Jun Cai et al.   Stem Cell Reports

CluePedia Cytoscape plugin: pathway insights using integrated experimental and in silico data

(2013) Gabriela Bindea et al.   BIOINFORMATICS

Cellular Complexity of the Bone Marrow Hematopoietic Stem Cell Niche

(2013) Laura M. Calvi et al.   CALCIFIED TISSUE INTERNATIONAL

Myeloproliferative Neoplasia Remodels the Endosteal Bone Marrow Niche into a Self-Reinforcing Leukemic Niche

(2013) Koen Schepers et al.   Cell Stem Cell

Leukemia cells induce changes in human bone marrow stromal cells

(2013) Sara Civini et al.   Journal of Translational Medicine

Insufficient stromal support in MDS results from molecular and functional deficits of mesenchymal stromal cells

(2013) S Geyh et al.   LEUKEMIA

DNA Methylation Changes duringIn VitroPropagation of Human Mesenchymal Stem Cells: Implications for Their Genomic Stability?

(2013) Angela Bentivegna et al.   Stem Cells International

Metabolic remodeling of the tumor microenvironment: Migration stimulating factor (MSF) reprograms myofibroblasts toward lactate production, fueling anabolic tumor growth

(2012) Valentina Carito et al.   CELL CYCLE

More than matrix: The multifaceted role of decorin in cancer

(2012) David Denis Sofeu Feugaing et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

Decorin–TGFβ Axis in Hepatic Fibrosis and Cirrhosis

(2012) Kornélia Baghy et al.   JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY

Mesenchymal stem cells: a potential targeted-delivery vehicle for anti-cancer drug loaded nanoparticles

(2012) Zibin Gao et al.   Nanomedicine-Nanotechnology Biology and Medicine

Vascular niche E-selectin regulates hematopoietic stem cell dormancy, self renewal and chemoresistance

(2012) Ingrid G Winkler et al.   NATURE MEDICINE

Endocytosis and Signaling: Cell Logistics Shape the Eukaryotic Cell Plan

(2012) Sara Sigismund et al.   PHYSIOLOGICAL REVIEWS

Tumor-Derived Microvesicles Induce Proangiogenic Phenotype in Endothelial Cells via Endocytosis

(2012) Taisuke Kawamoto et al.   PLoS One

Mesenchymal stromal cells of myelodysplastic syndrome and acute myeloid leukemia patients have distinct genetic abnormalities compared with leukemic blasts

(2011) O. Blau et al.   BLOOD

The canonical Wnt pathway shapes niches supportive of hematopoietic stem/progenitor cells

(2011) M. Ichii et al.   BLOOD

Plectin-1 as a Novel Biomarker for Pancreatic Cancer

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Proteoglycans in cancer biology, tumour microenvironment and angiogenesis

(2010) Renato V. Iozzo et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Bone progenitor dysfunction induces myelodysplasia and secondary leukaemia

(2010) Marc H. G. P. Raaijmakers et al.   NATURE

A human functional protein interaction network and its application to cancer data analysis

(2010) Guanming Wu et al.   GENOME BIOLOGY

ClueGO: a Cytoscape plug-in to decipher functionally grouped gene ontology and pathway annotation networks

(2009) Gabriela Bindea et al.   BIOINFORMATICS

Decorin is a novel antagonistic ligand of the Met receptor

(2009) Silvia Goldoni et al.   JOURNAL OF CELL BIOLOGY

Endocytosis and signalling: intertwining molecular networks

(2009) Alexander Sorkin et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Leukemic Cells Create Bone Marrow Niches That Disrupt the Behavior of Normal Hematopoietic Progenitor Cells

(2008) Angela Colmone et al.   SCIENCE