The canonical Wnt pathway shapes niches supportive of hematopoietic stem/progenitor cells

Contrasting Responses of Lymphoid Progenitors to Canonical and Noncanonical Wnt Signals

(2014) S. Malhotra et al.   JOURNAL OF IMMUNOLOGY

Soluble Frizzled-Related Protein 1 Is Estrogen Inducible in Bone Marrow Stromal Cells and Suppresses the Earliest Events in Lymphopoiesis

(2014) T. Yokota et al.   JOURNAL OF IMMUNOLOGY

Wnt-inhibitory factor 1 dysregulation of the bone marrow niche exhausts hematopoietic stem cells

(2011) C. Schaniel et al.   BLOOD

Differential niche and Wnt requirements during acute myeloid leukemia progression

(2011) S. W. Lane et al.   BLOOD

Canonical Wnt Signaling Regulates Hematopoiesis in a Dosage-Dependent Fashion

(2011) Tiago C. Luis et al.   Cell Stem Cell

The bone marrow stem cell niche grows up: mesenchymal stem cells and macrophages move in

(2011) Armin Ehninger et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Bone marrow CD169+macrophages promote the retention of hematopoietic stem and progenitor cells in the mesenchymal stem cell niche

(2011) Andrew Chow et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Stem cell gene expression programs influence clinical outcome in human leukemia

(2011) Kolja Eppert et al.   NATURE MEDICINE

Control of hematopoietic stem cells by the bone marrow stromal niche: the role of reticular cells

(2011) Takashi Nagasawa et al.   TRENDS IN IMMUNOLOGY

The Apcmin mouse has altered hematopoietic stem cell function and provides a model for MPD/MDS

(2010) S. W. Lane et al.   BLOOD

Natural killer-cell differentiation by myeloid progenitors

(2010) B. Grzywacz et al.   BLOOD

Bone marrow macrophages maintain hematopoietic stem cell (HSC) niches and their depletion mobilizes HSCs

(2010) I. G. Winkler et al.   BLOOD

Positioning of bone marrow hematopoietic and stromal cells relative to blood flow in vivo: serially reconstituting hematopoietic stem cells reside in distinct nonperfused niches

(2010) I. G. Winkler et al.   BLOOD

Early B Cell Factor 2 Regulates Hematopoietic Stem Cell Homeostasis in a Cell-Nonautonomous Manner

(2010) Matthias Kieslinger et al.   Cell Stem Cell

Proteoglycans in health and disease: novel regulatory signaling mechanisms evoked by the small leucine-rich proteoglycans

(2010) Renato V. Iozzo et al.   FEBS Journal

Decorin Antagonizes Met Receptor Activity and Down-regulates β-Catenin and Myc Levels

(2010) Simone Buraschi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mesenchymal and haematopoietic stem cells form a unique bone marrow niche

(2010) Simón Méndez-Ferrer et al.   NATURE

O2 regulates stem cells through Wnt/β-catenin signalling

(2010) Jolly Mazumdar et al.   NATURE CELL BIOLOGY

Molecular Signatures of Quiescent, Mobilized and Leukemia-Initiating Hematopoietic Stem Cells

(2010) E. Camilla Forsberg et al.   PLoS One

The Wnt/ -Catenin Pathway Is Required for the Development of Leukemia Stem Cells in AML

(2010) Y. Wang et al.   SCIENCE

Wnt-Related Molecules and Signaling Pathway Equilibrium in Hematopoiesis

(2009) Sachin Malhotra et al.   Cell Stem Cell

Secreted Frizzled-Related Protein 1 Extrinsically Regulates Cycling Activity and Maintenance of Hematopoietic Stem Cells

(2009) Jonas Renström et al.   Cell Stem Cell

Non-canonical Wnt signaling pathways in hematopoiesis

(2009) Kathleen Kokolus et al.   IMMUNOLOGIC RESEARCH

β-Catenin Expression in the Bone Marrow Microenvironment Is Required for Long-Term Maintenance of Primitive Hematopoietic Cells

(2009) Michael J. Nemeth et al.   STEM CELLS

Identification of a Stroma-Mediated Wnt/β-Catenin Signal Promoting Self-Renewal of Hematopoietic Stem Cells in the Stem Cell Niche

(2009) Jin-A Kim et al.   STEM CELLS

Wnt3a deficiency irreversibly impairs hematopoietic stem cell self-renewal and leads to defects in progenitor cell differentiation

(2008) T. C. Luis et al.   BLOOD

Genetic deficiency of decorin causes intestinal tumor formation through disruption of intestinal cell maturation

(2008) X. Bi et al.   CARCINOGENESIS

Wnt Signaling in the Niche Enforces Hematopoietic Stem Cell Quiescence and Is Necessary to Preserve Self-Renewal In Vivo

(2008) Heather E. Fleming et al.   Cell Stem Cell

Regulation of human B lymphopoiesis by the transforming growth factor-β superfamily in a newly established coculture system using human mesenchymal stem cells as a supportive microenvironment

(2008) Michiko Ichii et al.   EXPERIMENTAL HEMATOLOGY

Canonical Wnt pathway signaling suppresses VCAM-1 expression by marrow stromal and hematopoietic cells

(2008) Sachin Malhotra et al.   EXPERIMENTAL HEMATOLOGY

Transcriptome-wide noise controls lineage choice in mammalian progenitor cells

(2008) Hannah H. Chang et al.   NATURE

Endochondral ossification is required for haematopoietic stem-cell niche formation

(2008) Charles K. F. Chan et al.   NATURE