Altered mesenchymal niche cells impede generation of normal hematopoietic progenitor cells in leukemic bone marrow

Osteoprotegerin induces podosome disassembly in osteoclasts through calcium, ERK, and p38 MAPK signaling pathways

(2015) Hongyan Zhao et al.   CYTOKINE

Ncor2 is required for hematopoietic stem cell emergence by inhibiting Fos signaling in zebrafish

(2014) Y. Wei et al.   BLOOD

A Systems Biology Approach for Defining the Molecular Framework of the Hematopoietic Stem Cell Niche

(2014) Pierre Charbord et al.   Cell Stem Cell

Acute Myelogenous Leukemia-Induced Sympathetic Neuropathy Promotes Malignancy in an Altered Hematopoietic Stem Cell Niche

(2014) Maher Hanoun et al.   Cell Stem Cell

Notch1-induced T cell leukemia can be potentiated by microenvironmental cues in the spleen

(2014) Shihui Ma et al.   Journal of Hematology & Oncology

The bone marrow niche for haematopoietic stem cells

(2014) Sean J. Morrison et al.   NATURE

Hematopoietic stem cell niche maintenance during homeostasis and regeneration

(2014) Avital Mendelson et al.   NATURE MEDICINE

Mesenchymal Stromal Cells Derived from the Bone Marrow of Acute Lymphoblastic Leukemia Patients Show Altered BMP4 Production: Correlations with the Course of Disease

(2014) Ángeles Vicente López et al.   PLoS One

Myeloproliferative Neoplasia Remodels the Endosteal Bone Marrow Niche into a Self-Reinforcing Leukemic Niche

(2013) Koen Schepers et al.   Cell Stem Cell

Biological, Functional and Genetic Characterization of Bone Marrow-Derived Mesenchymal Stromal Cells from Pediatric Patients Affected by Acute Lymphoblastic Leukemia

(2013) Antonella Conforti et al.   PLoS One

Acute myeloid leukemia does not deplete normal hematopoietic stem cells but induces cytopenias by impeding their differentiation

(2013) F. Miraki-Moud et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Altered Microenvironmental Regulation of Leukemic and Normal Stem Cells in Chronic Myelogenous Leukemia

(2012) Bin Zhang et al.   CANCER CELL

Endogenous Bone Marrow MSCs Are Dynamic, Fate-Restricted Participants in Bone Maintenance and Regeneration

(2012) Dongsu Park et al.   Cell Stem Cell

Endothelial and perivascular cells maintain haematopoietic stem cells

(2012) Lei Ding et al.   NATURE

Isolation of mouse mesenchymal stem cells on the basis of expression of Sca-1 and PDGFR-α

(2012) Diarmaid D Houlihan et al.   Nature Protocols

Osteoprotegerin Positively Regulates Hematopoietic Progenitor Cells

(2012) Eric Schweikle et al.   Current Stem Cell Research & Therapy

The HSC niche concept has turned 31

(2010) Stefania Lymperi et al.   Annals of the New York Academy of Sciences

The ARF tumor suppressor: Structure, functions and status in cancer

(2010) Peggy Ozenne et al.   INTERNATIONAL JOURNAL OF CANCER

Mesenchymal and haematopoietic stem cells form a unique bone marrow niche

(2010) Simón Méndez-Ferrer et al.   NATURE

Kinetics of normal hematopoietic stem and progenitor cells in a Notch1-induced leukemia model

(2009) X. Hu et al.   BLOOD

Prospective identification, isolation, and systemic transplantation of multipotent mesenchymal stem cells in murine bone marrow

(2009) Satoru Morikawa et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Stem cell traits in long-term co-culture revealed by time-lapse imaging

(2009) Y Song et al.   LEUKEMIA

Isolation and characterization of CD146+ multipotent mesenchymal stromal cells

(2008) Antonio Sorrentino et al.   EXPERIMENTAL HEMATOLOGY

Leukemic Cells Create Bone Marrow Niches That Disrupt the Behavior of Normal Hematopoietic Progenitor Cells

(2008) Angela Colmone et al.   SCIENCE