Sensitizing acute myeloid leukemia cells to induced differentiation by inhibiting the RIP1/RIP3 pathway
出版年份 2016 全文链接
标题
Sensitizing acute myeloid leukemia cells to induced differentiation by inhibiting the RIP1/RIP3 pathway
作者
关键词
-
出版物
LEUKEMIA
Volume 31, Issue 5, Pages 1154-1165
出版商
Springer Nature
发表日期
2016-10-17
DOI
10.1038/leu.2016.287
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- RIPK3 Restricts Myeloid Leukemogenesis by Promoting Cell Death and Differentiation of Leukemia Initiating Cells
- (2016) Ulrike Höckendorf et al. CANCER CELL
- Eradication of Acute Myeloid Leukemia with FLT3 Ligand-Targeted miR-150 Nanoparticles
- (2016) X. Jiang et al. CANCER RESEARCH
- Cancer therapy in the necroptosis era
- (2016) Z Su et al. CELL DEATH AND DIFFERENTIATION
- Necroptosis and its role in inflammation
- (2015) Manolis Pasparakis et al. NATURE
- The diverse role of RIP kinases in necroptosis and inflammation
- (2015) John Silke et al. NATURE IMMUNOLOGY
- FAK Mediates a Compensatory Survival Signal Parallel to PI3K-AKT in PTEN-Null T-ALL Cells
- (2015) Dewen You et al. Cell Reports
- Esthesioneuroblastoma
- (2014) Kelly K. Gallagher et al. ANNALS OF OTOLOGY RHINOLOGY AND LARYNGOLOGY
- RIPK1 Regulates RIPK3-MLKL-Driven Systemic Inflammation and Emergency Hematopoiesis
- (2014) James A. Rickard et al. CELL
- RIPK1 Blocks Early Postnatal Lethality Mediated by Caspase-8 and RIPK3
- (2014) Christopher P. Dillon et al. CELL
- Co-inhibition of NF-κB and JNK is synergistic in TNF-expressing human AML
- (2014) Andrew Volk et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Inhibitor of Apoptosis (IAP) proteins in hematological malignancies: molecular mechanisms and therapeutic opportunities
- (2014) S Fulda LEUKEMIA
- RIP3 Induces Apoptosis Independent of Pronecrotic Kinase Activity
- (2014) Pratyusha Mandal et al. MOLECULAR CELL
- RIPK1 ensures intestinal homeostasis by protecting the epithelium against apoptosis
- (2014) Nozomi Takahashi et al. NATURE
- RIPK1 maintains epithelial homeostasis by inhibiting apoptosis and necroptosis
- (2014) Marius Dannappel et al. NATURE
- Necroptosis
- (2014) Andreas Linkermann et al. NEW ENGLAND JOURNAL OF MEDICINE
- Small-molecule SMAC mimetics as new cancer therapeutics
- (2014) Longchuan Bai et al. PHARMACOLOGY & THERAPEUTICS
- Type-I interferon signaling through ISGF3 complex is required for sustained Rip3 activation and necroptosis in macrophages
- (2014) S. McComb et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Hematopoietic RIPK1 deficiency results in bone marrow failure caused by apoptosis and RIPK3-mediated necroptosis
- (2014) Justine E. Roderick et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Activity of Protein Kinase RIPK3 Determines Whether Cells Die by Necroptosis or Apoptosis
- (2014) K. Newton et al. SCIENCE
- Necroptosis in health and diseases
- (2014) Wen Zhou et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- The mechanism of necroptosis in normal and cancer cells
- (2013) Simone Fulda CANCER BIOLOGY & THERAPY
- A Pan-BCL2 Inhibitor Renders Bone-Marrow-Resident Human Leukemia Stem Cells Sensitive to Tyrosine Kinase Inhibition
- (2013) Daniel J. Goff et al. Cell Stem Cell
- BCL-2 Inhibition Targets Oxidative Phosphorylation and Selectively Eradicates Quiescent Human Leukemia Stem Cells
- (2013) Eleni D. Lagadinou et al. Cell Stem Cell
- Toll-like Receptor 3-mediated Necrosis via TRIF, RIP3, and MLKL
- (2013) William J. Kaiser et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- p27kip1 maintains a subset of leukemia stem cells in the quiescent state in murine MLL-leukemia
- (2013) Jun Zhang et al. Molecular Oncology
- Smac mimetic and demethylating agents synergistically trigger cell death in acute myeloid leukemia cells and overcome apoptosis resistance by inducing necroptosis
- (2013) L Steinhart et al. Cell Death & Disease
- Histologic Tumor Necrosis Is an Independent Prognostic Indicator for Clear Cell and Papillary Renal Cell Carcinoma
- (2012) Martin Pichler et al. AMERICAN JOURNAL OF CLINICAL PATHOLOGY
- Activity and specificity of necrostatin-1, small-molecule inhibitor of RIP1 kinase
- (2012) A Degterev et al. CELL DEATH AND DIFFERENTIATION
- Ubiquitination in signaling to and activation of IKK
- (2012) Zhijian J. Chen IMMUNOLOGICAL REVIEWS
- How to manage acute promyelocytic leukemia
- (2012) J-Q Mi et al. LEUKEMIA
- Targeting IAP proteins for therapeutic intervention in cancer
- (2012) Simone Fulda et al. NATURE REVIEWS DRUG DISCOVERY
- Necrostatin-1 analogues: critical issues on the specificity, activity and in vivo use in experimental disease models
- (2012) N Takahashi et al. Cell Death & Disease
- TNF- /Fas-RIP-1-induced cell death signaling separates murine hematopoietic stem cells/progenitors into 2 distinct populations
- (2011) Y. Xiao et al. BLOOD
- From an old remedy to a magic bullet: molecular mechanisms underlying the therapeutic effects of arsenic in fighting leukemia
- (2011) S.-J. Chen et al. BLOOD
- Many stimuli pull the necrotic trigger, an overview
- (2011) N Vanlangenakker et al. CELL DEATH AND DIFFERENTIATION
- Therapeutic Advances in Acute Myeloid Leukemia
- (2011) Alan Burnett et al. JOURNAL OF CLINICAL ONCOLOGY
- Curing APL through PML/RARA degradation by As2O3
- (2011) Valerie Lallemand-Breitenbach et al. TRENDS IN MOLECULAR MEDICINE
- XIAP antisense oligonucleotide (AEG35156) achieves target knockdown and induces apoptosis preferentially in CD34+38− cells in a phase 1/2 study of patients with relapsed/refractory AML
- (2010) Bing Z. Carter et al. APOPTOSIS
- Non-canonical NF-κB signaling pathway
- (2010) Shao-Cong Sun CELL RESEARCH
- Novel second mitochondria-derived activator of caspases (Smac) mimetic compounds sensitize human leukemic cell lines to conventional chemotherapeutic drug-induced and death receptor-mediated apoptosis
- (2010) Federica Servida et al. INVESTIGATIONAL NEW DRUGS
- Smac mimetics: implications for enhancement of targeted therapies in leukemia
- (2010) E Weisberg et al. LEUKEMIA
- Expected long-term survival of patients diagnosed with acute myeloblastic leukemia during 2006–2010
- (2009) D. Pulte et al. ANNALS OF ONCOLOGY
- The Role of Ubiquitin in NF-κB Regulatory Pathways
- (2009) Brian Skaug et al. Annual Review of Biochemistry
- Smac mimetics as new cancer therapeutics
- (2009) Derrick J. Chen et al. ANTI-CANCER DRUGS
- Phosphorylation-Driven Assembly of the RIP1-RIP3 Complex Regulates Programmed Necrosis and Virus-Induced Inflammation
- (2009) YoungSik Cho et al. CELL
- Phase I/II Trial of AEG35156 X-Linked Inhibitor of Apoptosis Protein Antisense Oligonucleotide Combined With Idarubicin and Cytarabine in Patients With Relapsed or Primary Refractory Acute Myeloid Leukemia
- (2009) Aaron D. Schimmer et al. JOURNAL OF CLINICAL ONCOLOGY
- Phase I Trial of AEG35156 Administered as a 7-Day and 3-Day Continuous Intravenous Infusion in Patients With Advanced Refractory Cancer
- (2009) Emma Dean et al. JOURNAL OF CLINICAL ONCOLOGY
- Attempts to Optimize Induction and Consolidation Treatment in Acute Myeloid Leukemia: Results of the MRC AML12 Trial
- (2009) Alan K. Burnett et al. JOURNAL OF CLINICAL ONCOLOGY
- Anthracycline Dose Intensification in Acute Myeloid Leukemia
- (2009) Hugo F. Fernandez et al. NEW ENGLAND JOURNAL OF MEDICINE
- Apoptosis in leukemia: From molecular pathways to targeted therapies
- (2008) Aaron D. Schimmer BEST PRACTICE & RESEARCH CLINICAL HAEMATOLOGY
- Cancer-related inflammation
- (2008) Alberto Mantovani et al. NATURE
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