DNMT3A R882H mutant and Tet2 inactivation cooperate in the deregulation of DNA methylation control to induce lymphoid malignancies in mice
出版年份 2016 全文链接
标题
DNMT3A
R882H
mutant and Tet2 inactivation cooperate in the deregulation of DNA methylation control to induce lymphoid malignancies in mice
作者
关键词
-
出版物
LEUKEMIA
Volume 30, Issue 6, Pages 1388-1398
出版商
Springer Nature
发表日期
2016-02-15
DOI
10.1038/leu.2016.29
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Mutational Cooperativity Linked to Combinatorial Epigenetic Gain of Function in Acute Myeloid Leukemia
- (2015) Alan H. Shih et al. CANCER CELL
- Loss ofTET2in hematopoietic cells leads to DNA hypermethylation of active enhancers and induction of leukemogenesis
- (2015) Kasper D. Rasmussen et al. GENES & DEVELOPMENT
- Disregulated expression of the transcription factor ThPOK during T-cell development leads to high incidence of T-cell lymphomas
- (2015) Hyung-Ok Lee et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- INPP4B Is a PtdIns(3,4,5)P3 Phosphatase That Can Act as a Tumor Suppressor
- (2015) S. Kofuji et al. Cancer Discovery
- In Vivo Role of INPP4B in Tumor and Metastasis Suppression through Regulation of PI3K-AKT Signaling at Endosomes
- (2015) C. Li Chew et al. Cancer Discovery
- TET proteins and the control of cytosine demethylation in cancer
- (2015) Laurianne Scourzic et al. Genome Medicine
- Distinct effects of concomitant Jak2V617F expression and Tet2 loss in mice promote disease progression in myeloproliferative neoplasms
- (2014) E. Chen et al. BLOOD
- Dnmt3a loss predisposes murine hematopoietic stem cells to malignant transformation
- (2014) A. Mayle et al. BLOOD
- Loss of TET2 has dual roles in murine myeloproliferative neoplasms: disease sustainer and disease accelerator
- (2014) T. Kameda et al. BLOOD
- The R882H DNMT3A Mutation Associated with AML Dominantly Inhibits Wild-Type DNMT3A by Blocking Its Ability to Form Active Tetramers
- (2014) David A. Russler-Germain et al. CANCER CELL
- Specific fibroblastic niches in secondary lymphoid organs orchestrate distinct Notch-regulated immune responses
- (2014) Nicolas Fasnacht et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Somatic RHOA mutation in angioimmunoblastic T cell lymphoma
- (2014) Mamiko Sakata-Yanagimoto et al. NATURE GENETICS
- Recurrent mutations in epigenetic regulators, RHOA and FYN kinase in peripheral T cell lymphomas
- (2014) Teresa Palomero et al. NATURE GENETICS
- TCF-1 and LEF-1 act upstream of Th-POK to promote the CD4+ T cell fate and interact with Runx3 to silence Cd4 in CD8+ T cells
- (2014) Farrah C Steinke et al. NATURE IMMUNOLOGY
- Dissecting the dynamic changes of 5-hydroxymethylcytosine in T-cell development and differentiation
- (2014) A. Tsagaratou et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Reduced TET2 function leads to T-cell lymphoma with follicular helper T-cell-like features in mice
- (2014) H Muto et al. Blood Cancer Journal
- Whole-exome sequencing in adult ETP-ALL reveals a high rate of DNMT3A mutations
- (2013) M. Neumann et al. BLOOD
- TCF-1 mediates repression of Notch pathway in T lineage-committed early thymocytes
- (2013) S. Yu et al. BLOOD
- A DNMT3A mutation common in AML exhibits dominant-negative effects in murine ES cells
- (2013) S. J. Kim et al. BLOOD
- The molecular profile of adult T-cell acute lymphoblastic leukemia: Mutations inRUNX1andDNMT3Aare associated with poor prognosis in T-ALL
- (2013) Vera Grossmann et al. GENES CHROMOSOMES & CANCER
- Notch pathway activation targets AML-initiating cell homeostasis and differentiation
- (2013) Camille Lobry et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Concurrent loss of Ezh2 and Tet2 cooperates in the pathogenesis of myelodysplastic disorders
- (2013) Tomoya Muto et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Notch Signaling Regulates Follicular Helper T Cell Differentiation
- (2013) F. Auderset et al. JOURNAL OF IMMUNOLOGY
- Tumor suppressor functions of Dnmt3a and Dnmt3b in the prevention of malignant mouse lymphopoiesis
- (2013) S L Peters et al. LEUKEMIA
- Gauging NOTCH1 Activation in Cancer Using Immunohistochemistry
- (2013) Michael J. Kluk et al. PLoS One
- Heterozygosity for Roquinsan leads to angioimmunoblastic T-cell lymphoma-like tumors in mice
- (2012) J. I. Ellyard et al. BLOOD
- In aggressive forms of mastocytosis, TET2 loss cooperates with c-KITD816V to transform mast cells
- (2012) E. Soucie et al. BLOOD
- Recurrent TET2 mutations in peripheral T-cell lymphomas correlate with TFH-like features and adverse clinical parameters
- (2012) F. Lemonnier et al. BLOOD
- Tales of the Unexpected: Tcf1 Functions as a Tumor Suppressor for Leukemias
- (2012) Frank J.T. Staal et al. IMMUNITY
- Characterization of novel genomic alterations and therapeutic approaches using acute megakaryoblastic leukemia xenograft models
- (2012) Clarisse Thiollier et al. JOURNAL OF EXPERIMENTAL MEDICINE
- TET2andDNMT3AMutations in Human T-Cell Lymphoma
- (2012) Lucile Couronné et al. NEW ENGLAND JOURNAL OF MEDICINE
- Follicular Helper CD4 T Cells (TFH)
- (2011) Shane Crotty Annual Review of Immunology
- TET2 Inactivation Results in Pleiotropic Hematopoietic Abnormalities in Mouse and Is a Recurrent Event during Human Lymphomagenesis
- (2011) Cyril Quivoron et al. CANCER CELL
- Identification of recurring tumor-specific somatic mutations in acute myeloid leukemia by transcriptome sequencing
- (2011) P A Greif et al. LEUKEMIA
- TET1 and hydroxymethylcytosine in transcription and DNA methylation fidelity
- (2011) Kristine Williams et al. NATURE
- Dnmt3a is essential for hematopoietic stem cell differentiation
- (2011) Grant A Challen et al. NATURE GENETICS
- Exome sequencing identifies somatic mutations of DNA methyltransferase gene DNMT3A in acute monocytic leukemia
- (2011) Xiao-Jing Yan et al. NATURE GENETICS
- Preparation of reduced representation bisulfite sequencing libraries for genome-scale DNA methylation profiling
- (2011) Hongcang Gu et al. Nature Protocols
- DNMT3AMutations in Acute Myeloid Leukemia
- (2010) Timothy J. Ley et al. NEW ENGLAND JOURNAL OF MEDICINE
- Acquired mutations in TET2 are common in myelodysplastic syndromes
- (2009) Saskia M C Langemeijer et al. NATURE GENETICS
- DNA methylation protects hematopoietic stem cell multipotency from myeloerythroid restriction
- (2009) Ann-Marie Bröske et al. NATURE GENETICS
- Mutation inTET2in Myeloid Cancers
- (2009) François Delhommeau et al. NEW ENGLAND JOURNAL OF MEDICINE
- Activating mutations in human acute megakaryoblastic leukemia
- (2008) S. Malinge et al. BLOOD
- Microenvironment Determines Lineage Fate in a Human Model of MLL-AF9 Leukemia
- (2008) Junping Wei et al. CANCER CELL
- Leukemia-associated NOTCH1 alleles are weak tumor initiators but accelerate K-ras–initiated leukemia
- (2008) Mark Y. Chiang et al. JOURNAL OF CLINICAL INVESTIGATION
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