Diet-induced loss of adipose hexokinase 2 correlates with hyperglycemia

The role of somatosensory innervation of adipose tissues

(2022) Yu Wang et al.   NATURE

Adipose mTORC2 is essential for sensory innervation in white adipose tissue and whole-body energy homeostasis

(2022) Irina C. Frei et al.   Molecular Metabolism

Sensory neurons expressing calcitonin gene-related peptide α regulate adaptive thermogenesis and diet-induced obesity

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The mutational constraint spectrum quantified from variation in 141,456 humans

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FOXK1 and FOXK2 regulate aerobic glycolysis

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Carbohydrate Sensing Through the Transcription Factor ChREBP

(2019) Paula Ortega-Prieto et al.   Frontiers in Genetics

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The catalytic inactivation of the N-half of human hexokinase 2 and structural and biochemical characterization of its mitochondrial conformation

(2018) Mir Hussain Nawaz et al.   BIOSCIENCE REPORTS

Insulin resistance causes inflammation in adipose tissue

(2018) Mitsugu Shimobayashi et al.   JOURNAL OF CLINICAL INVESTIGATION

Hexokinase-2 depletion inhibits glycolysis and induces oxidative phosphorylation in hepatocellular carcinoma and sensitizes to metformin

(2018) Dannielle DeWaal et al.   Nature Communications

Insulin resistance in cavefish as an adaptation to a nutrient-limited environment

(2018) Misty R. Riddle et al.   NATURE

Calcium Channel CaV2.3 Subunits Regulate Hepatic Glucose Production by Modulating Leptin-Induced Excitation of Arcuate Pro-opiomelanocortin Neurons

(2018) Mark A. Smith et al.   Cell Reports

Proline metabolism supports metastasis formation and could be inhibited to selectively target metastasizing cancer cells

(2017) Ilaria Elia et al.   Nature Communications

Absence of Carbohydrate Response Element Binding Protein in Adipocytes Causes Systemic Insulin Resistance and Impairs Glucose Transport

(2017) Archana Vijayakumar et al.   Cell Reports

Distinct Akt phosphorylation states are required for insulin regulated Glut4 and Glut1-mediated glucose uptake

(2017) Muheeb Beg et al.   eLife

Direct Hepatocyte Insulin Signaling Is Required for Lipogenesis but Is Dispensable for the Suppression of Glucose Production

(2016) Paul M. Titchenell et al.   Cell Metabolism

Disruption of Adipose Rab10-Dependent Insulin Signaling Causes Hepatic Insulin Resistance

(2016) Reema P. Vazirani et al.   DIABETES

ChREBP regulates fructose-induced glucose production independently of insulin signaling

(2016) Mi-Sung Kim et al.   JOURNAL OF CLINICAL INVESTIGATION

Evaluation and Improvement of Quantification Accuracy in Isobaric Mass Tag-Based Protein Quantification Experiments

(2016) Erik Ahrné et al.   JOURNAL OF PROTEOME RESEARCH

Adipose tissue mTORC2 regulates ChREBP-driven de novo lipogenesis and hepatic glucose metabolism

(2016) Yuefeng Tang et al.   Nature Communications

Lack of AKT in adipocytes causes severe lipodystrophy

(2016) Abigail L. Shearin et al.   Molecular Metabolism

Hepatic Acetyl CoA Links Adipose Tissue Inflammation to Hepatic Insulin Resistance and Type 2 Diabetes

(2015) Rachel J. Perry et al.   CELL

Selective Insulin Resistance in Adipocytes

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The regulation of glucose metabolism: implications and considerations for the assessment of glucose homeostasis in rodents

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Hexokinase 2 Is Required for Tumor Initiation and Maintenance and Its Systemic Deletion Is Therapeutic in Mouse Models of Cancer

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Protocol for effective differentiation of 3T3-L1 cells to adipocytes

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A novel ChREBP isoform in adipose tissue regulates systemic glucose metabolism

(2012) Mark A. Herman et al.   NATURE

Glucose 6-phosphate, rather than xylulose 5-phosphate, is required for the activation of ChREBP in response to glucose in the liver

(2011) Renaud Dentin et al.   JOURNAL OF HEPATOLOGY

Reversed-phase chromatography with multiple fraction concatenation strategy for proteome profiling of human MCF10A cells

(2011) Yuexi Wang et al.   PROTEOMICS

Glucose-6-phosphate mediates activation of the carbohydrate responsive binding protein (ChREBP)

(2010) Ming V. Li et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Fat Cell-Specific Ablation of Rictor in Mice Impairs Insulin-Regulated Fat Cell and Whole-Body Glucose and Lipid Metabolism

(2010) A. Kumar et al.   DIABETES

Chronically increased glucose uptake by adipose tissue leads to lactate production and improved insulin sensitivity rather than obesity in the mouse

(2010) S. Muñoz et al.   DIABETOLOGIA

Tamoxifen-inducible Cre-mediated recombination in adipocytes

(2010) Antonia Sassmann et al.   GENESIS

mTOR complex 2 in adipose tissue negatively controls whole-body growth

(2009) N. Cybulski et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Four grams of glucose

(2008) David H. Wasserman   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Anterograde transneuronal viral tract tracing reveals central sensory circuits from white adipose tissue

(2008) C. Kay Song et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Selective versus Total Insulin Resistance: A Pathogenic Paradox

(2008) Michael S. Brown et al.   Cell Metabolism