The effects of caloric restriction on adipose tissue and metabolic health are sex- and age-dependent

Circadian alignment of early onset caloric restriction promotes longevity in male C57BL/6J mice

(2022) Victoria Acosta-Rodríguez et al.   SCIENCE

Sex- and age-dependent outcomes of 9-hour time-restricted feeding of a Western high-fat high-sucrose diet in C57BL/6J mice

(2021) Amandine Chaix et al.   Cell Reports

Genetic architecture of 11 organ traits derived from abdominal MRI using deep learning

(2021) Yi Liu et al.   eLife

Sexually Dimorphic Effects of Dietary Methionine Restriction are Dependent on Age when the Diet is Introduced

(2020) Laura A. Forney et al.   Obesity

Estrogenic control of mitochondrial function

(2020) Carolyn M. Klinge   Redox Biology

Differential responses of white adipose tissue and brown adipose tissue to calorie restriction during aging

(2020) Yunlu Sheng et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Bone marrow adipose tissue is a unique adipose subtype with distinct roles in glucose homeostasis

(2020) Karla J. Suchacki et al.   Nature Communications

The ARRIVE guidelines 2.0: Updated guidelines for reporting animal research

(2020) Nathalie Percie du Sert et al.   PLOS BIOLOGY

X chromosome dosage of histone demethylase KDM5C determines sex differences in adiposity

(2020) Jenny C. Link et al.   JOURNAL OF CLINICAL INVESTIGATION

The impact of sex on gene expression across human tissues

(2020) Meritxell Oliva et al.   SCIENCE

The role of C16:0 ceramide in the development of obesity and type 2 diabetes: CerS6 inhibition as a novel therapeutic approach

(2019) Suryaprakash Raichur et al.   Molecular Metabolism

The Impact of Aging on Adipose Function and Adipokine Synthesis

(2019) Peter Mancuso et al.   Frontiers in Endocrinology

Role of estrogen and its receptors mediated-autophagy in cell fate and human diseases

(2019) Yong Wei et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Targeting a ceramide double bond improves insulin resistance and hepatic steatosis

(2019) Bhagirath Chaurasia et al.   SCIENCE

2 years of calorie restriction and cardiometabolic risk (CALERIE): exploratory outcomes of a multicentre, phase 2, randomised controlled trial

(2019) William E Kraus et al.   Lancet Diabetes & Endocrinology

Timing of Calorie Restriction in Mice Impacts Host Metabolic Phenotype with Correlative Changes in Gut Microbiota

(2019) Liying Zhang et al.   mSystems

Mechanisms by which a Very-Low-Calorie Diet Reverses Hyperglycemia in a Rat Model of Type 2 Diabetes

(2018) Rachel J. Perry et al.   Cell Metabolism

Weight Gain and Impaired Glucose Metabolism in Women Are Predicted by Inefficient Subcutaneous Fat Cell Lipolysis

(2018) Peter Arner et al.   Cell Metabolism

Short-Term Fasting Reveals Amino Acid Metabolism as a Major Sex-Discriminating Factor in the Liver

(2018) Sara Della Torre et al.   Cell Metabolism

Genetic, dietary, and sex-specific regulation of hepatic ceramides and the relationship between hepatic ceramides and IR

(2018) Frode Norheim et al.   JOURNAL OF LIPID RESEARCH

Gender differences in glucose homeostasis and diabetes

(2018) Franck Mauvais-Jarvis   PHYSIOLOGY & BEHAVIOR

Sex, metabolism and health

(2018) Adriana Maggi et al.   Molecular Metabolism

Sex and gender differences in developmental programming of metabolism

(2018) Laura Dearden et al.   Molecular Metabolism

Remission of Human Type 2 Diabetes Requires Decrease in Liver and Pancreas Fat Content but Is Dependent upon Capacity for β Cell Recovery

(2018) Roy Taylor et al.   Cell Metabolism

Daily Fasting Improves Health and Survival in Male Mice Independent of Diet Composition and Calories

(2018) Sarah J. Mitchell et al.   Cell Metabolism

Quantification of Bone Fatty Acid Metabolism and Its Regulation by Adipocyte Lipoprotein Lipase

(2017) Alexander Bartelt et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The Effects of Graded Levels of Calorie Restriction: X. Transcriptomic Responses of Epididymal Adipose Tissue

(2017) Davina Derous et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Roles of Diacylglycerols and Ceramides in Hepatic Insulin Resistance

(2017) Max C. Petersen et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Caloric restriction improves health and survival of rhesus monkeys

(2017) Julie A. Mattison et al.   Nature Communications

The effects of graded levels of calorie restriction: VIII. Impact of short term calorie and protein restriction on basal metabolic rate in the C57BL/6 mouse

(2017) Sharon E. Mitchell et al.   Oncotarget

Sex matters: The effects of biological sex on adipose tissue biology and energy metabolism

(2017) Teresa G. Valencak et al.   Redox Biology

Metabolic Control of Longevity

(2016) Carlos López-Otín et al.   CELL

Effects of Sex, Strain, and Energy Intake on Hallmarks of Aging in Mice

(2016) Sarah J. Mitchell et al.   Cell Metabolism

Caloric Restriction Paradoxically Increases Adiposity in Mice With Genetically Reduced Insulin

(2016) Derek A. Dionne et al.   ENDOCRINOLOGY

Expansion of Bone Marrow Adipose Tissue During Caloric Restriction Is Associated With Increased Circulating Glucocorticoids and Not With Hypoleptinemia

(2016) William P. Cawthorn et al.   ENDOCRINOLOGY

Enrichr: a comprehensive gene set enrichment analysis web server 2016 update

(2016) Maxim V. Kuleshov et al.   NUCLEIC ACIDS RESEARCH

Can response to dietary restriction predict weight loss after Roux-en-Y gastroplasty?

(2016) Mirna Azar et al.   Obesity

Gender Differences in Response to Prolonged Every-Other-Day Feeding on the Proliferation and Apoptosis of Hepatocytes in Mice

(2016) Katarzyna Piotrowska et al.   Nutrients

Phylloquinone and Menaquinone-4 Tissue Distribution at Different Life Stages in Male and Female Sprague–Dawley Rats Fed Different VK Levels Since Weaning or Subjected to a 40% Calorie Restriction since Adulthood

(2016) Guylaine Ferland et al.   Nutrients

A Periodic Diet that Mimics Fasting Promotes Multi-System Regeneration, Enhanced Cognitive Performance, and Healthspan

(2015) Sebastian Brandhorst et al.   Cell Metabolism

Mechanism by which caloric restriction improves insulin sensitivity in sedentary obese adults

(2015) Matthew L. Johnson et al.   DIABETES

Sex Differences in Longevity and in Responses to Anti-Aging Interventions: A Mini-Review

(2015) Steven N. Austad et al.   GERONTOLOGY

Estrogens protect male mice from obesity complications and influence glucocorticoid metabolism

(2015) R S Dakin et al.   INTERNATIONAL JOURNAL OF OBESITY

Effect of Two-Year Caloric Restriction on Bone Metabolism and Bone Mineral Density in Non-Obese Younger Adults: A Randomized Clinical Trial

(2015) Dennis T Villareal et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Impact of Longevity Interventions on a Validated Mouse Clinical Frailty Index

(2015) Alice E. Kane et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

A Moderate Low-Carbohydrate Low-Calorie Diet Improves Lipid Profile, Insulin Sensitivity and Adiponectin Expression in Rats

(2015) Jie-Hua Chen et al.   Nutrients

The effects of graded levels of calorie restriction: I. impact of short term calorie and protein restriction on body composition in the C57BL/6 mouse

(2015) Sharon E. Mitchell et al.   Oncotarget

The effects of graded levels of calorie restriction: II. Impact of short term calorie and protein restriction on circulating hormone levels, glucose homeostasis and oxidative stress in male C57BL/6 mice

(2015) Sharon E. Mitchell et al.   Oncotarget

Estrogen: An Emerging Regulator of Insulin Action and Mitochondrial Function

(2015) Anisha A. Gupte et al.   Journal of Diabetes Research

Estrogen signaling prevents diet-induced hepatic insulin resistance in male mice with obesity

(2014) Lin Zhu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Obesity-Induced CerS6-Dependent C16:0 Ceramide Production Promotes Weight Gain and Glucose Intolerance

(2014) Sarah M. Turpin et al.   Cell Metabolism

CerS2 Haploinsufficiency Inhibits β-Oxidation and Confers Susceptibility to Diet-Induced Steatohepatitis and Insulin Resistance

(2014) Suryaprakash Raichur et al.   Cell Metabolism

Bone Marrow Adipose Tissue Is an Endocrine Organ that Contributes to Increased Circulating Adiponectin during Caloric Restriction

(2014) William P. Cawthorn et al.   Cell Metabolism

Female mice liberated for inclusion in neuroscience and biomedical research

(2014) Brian J. Prendergast et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

SIRT1 Functions as an Important Regulator of Estrogen-Mediated Cardiomyocyte Protection in Angiotensin II-Induced Heart Hypertrophy

(2014) Tao Shen et al.   Oxidative Medicine and Cellular Longevity

Does a Change in Health Research Funding Policy Related to the Integration of Sex and Gender Have an Impact?

(2014) Joy Johnson et al.   PLoS One

Long-Term Physiological Alterations and Recovery in a Mouse Model of Separation Associated with Time-Restricted Feeding: A Tool to Study Anorexia Nervosa Related Consequences

(2014) Sara Zgheib et al.   PLoS One

Endocrine consequences of anorexia nervosa

(2014) Madhusmita Misra et al.   Lancet Diabetes & Endocrinology

featureCounts: an efficient general purpose program for assigning sequence reads to genomic features

(2013) Y. Liao et al.   BIOINFORMATICS

Enrichr: interactive and collaborative HTML5 gene list enrichment analysis tool

(2013) Edward Y Chen et al.   BMC BIOINFORMATICS

Requirement for Mass Spectrometry Sex Steroid Assays in theJournal of Clinical Endocrinology and Metabolism

(2013) D. J. Handelsman et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

STAR: ultrafast universal RNA-seq aligner

(2012) Alexander Dobin et al.   BIOINFORMATICS

Ceramide Mediates Vascular Dysfunction in Diet-Induced Obesity by PP2A-Mediated Dephosphorylation of the eNOS-Akt Complex

(2012) Q.-J. Zhang et al.   DIABETES

Minireview: Translational Animal Models of Human Menopause: Challenges and Emerging Opportunities

(2012) Roberta Diaz Brinton   ENDOCRINOLOGY

Adiposoft: automated software for the analysis of white adipose tissue cellularity in histological sections

(2012) Miguel Galarraga et al.   JOURNAL OF LIPID RESEARCH

Calorie Restriction Enhances Insulin-Stimulated Glucose Uptake and Akt Phosphorylation in Both Fast-Twitch and Slow-Twitch Skeletal Muscle of 24-Month-Old Rats

(2012) D. A. Sequea et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Decreased systemic IGF-1 in response to calorie restriction modulates murine tumor cell growth, nuclear factor-κB activation, and inflammation-related gene expression

(2012) Alison E. Harvey et al.   MOLECULAR CARCINOGENESIS

Effects of protein intake and gender on body composition changes: a randomized clinical weight loss trial

(2012) Ellen M Evans et al.   Nutrition & Metabolism

Caloric Restriction Induces Changes in Insulin and Body Weight Measurements That Are Inversely Associated with Subsequent Weight Regain

(2012) Monica H. T. Wong et al.   PLoS One

Caloric restriction

(2011) John R. Speakman et al.   MOLECULAR ASPECTS OF MEDICINE

Effects of long-term calorie restriction and endurance exercise on glucose tolerance, insulin action, and adipokine production

(2009) Luigi Fontana et al.   AGE

Calorie restriction increases fatty acid synthesis and whole body fat oxidation rates

(2009) Matthew D. Bruss et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Adipose tissue and reproduction in women

(2009) Henry Bohler et al.   FERTILITY AND STERILITY

Improvements in body fat distribution and circulating adiponectin by alternate-day fasting versus calorie restriction☆

(2009) Krista A. Varady et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Mild Calorie Restriction Induces Fat Accumulation in Female C57BL/6J Mice

(2009) Xingsheng Li et al.   Obesity

Visceral adipose tissue modulates mammalian longevity

(2008) Radhika Muzumdar et al.   AGING CELL

Beneficial Effects of Subcutaneous Fat Transplantation on Metabolism

(2008) Thien T. Tran et al.   Cell Metabolism

Diet-induced adiposity alters the serum profile of inflammation in C57BL/6N mice as measured by antibody array

(2008) J. I. Fenton et al.   DIABETES OBESITY & METABOLISM