X chromosome dosage of histone demethylase KDM5C determines sex differences in adiposity

Cell-Type Heterogeneity in Adipose Tissue Is Associated with Complex Traits and Reveals Disease-Relevant Cell-Specific eQTLs

(2019) Craig A. Glastonbury et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Visceral and ectopic fat, atherosclerosis, and cardiometabolic disease: a position statement

(2019) Ian J Neeland et al.   Lancet Diabetes & Endocrinology

The X-linked histone demethylase Kdm6a in CD4+ T lymphocytes modulates autoimmunity

(2019) Yuichiro Itoh et al.   JOURNAL OF CLINICAL INVESTIGATION

Extracellular Matrix Remodeling of Adipose Tissue in Obesity and Metabolic Diseases

(2019) Ruiz-Ojeda et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Down-Regulation of a Male-Specific H3K4 Demethylase, KDM5D, Impairs Cardiomyocyte Differentiation

(2019) Anna Meyfour et al.   JOURNAL OF PROTEOME RESEARCH

Sex differences in the metabolic effects of diet-induced obesity vary by age of onset

(2018) Abigail E. Salinero et al.   INTERNATIONAL JOURNAL OF OBESITY

Epigenetic modifiers: activities in renal cell carcinoma

(2018) Aguirre A. de Cubas et al.   Nature Reviews Urology

Sex differences in obesity, lipid metabolism, and inflammation—A role for the sex chromosomes?

(2018) Temeka Zore et al.   Molecular Metabolism

KDM5D-mediated H3K4 demethylation is required for sexually dimorphic gene expression in mouse embryonic fibroblasts

(2018) Hayase Mizukami et al.   JOURNAL OF BIOCHEMISTRY

Lipin 2/3 phosphatidic acid phosphatases maintain phospholipid homeostasis to regulate chylomicron synthesis

(2018) Peixiang Zhang et al.   JOURNAL OF CLINICAL INVESTIGATION

The ominous triad of adipose tissue dysfunction: inflammation, fibrosis, and impaired angiogenesis

(2017) Clair Crewe et al.   JOURNAL OF CLINICAL INVESTIGATION

Landscape of X chromosome inactivation across human tissues

(2017) Taru Tukiainen et al.   NATURE

A complete tool set for molecular QTL discovery and analysis

(2017) Olivier Delaneau et al.   Nature Communications

Loss of chromosome Y leads to down regulation of KDM5D and KDM6C epigenetic modifiers in clear cell renal cell carcinoma

(2017) Madeleine Arseneault et al.   Scientific Reports

Adipose tissue-derived stromal vascular fraction in regenerative medicine: a brief review on biology and translation

(2017) Pablo Bora et al.   Stem Cell Research & Therapy

Adipose extracellular matrix remodelling in obesity and insulin resistance

(2016) De Lin et al.   BIOCHEMICAL PHARMACOLOGY

The KDM5 family is required for activation of pro-proliferative cell cycle genes during adipocyte differentiation

(2016) Ann-Sofie B. Brier et al.   NUCLEIC ACIDS RESEARCH

Enrichr: a comprehensive gene set enrichment analysis web server 2016 update

(2016) Maxim V. Kuleshov et al.   NUCLEIC ACIDS RESEARCH

A Mouse Model of X-linked Intellectual Disability Associated with Impaired Removal of Histone Methylation

(2016) Shigeki Iwase et al.   Cell Reports

A primer on the use of mouse models for identifying direct sex chromosome effects that cause sex differences in non-gonadal tissues

(2016) Paul S. Burgoyne et al.   Biology of Sex Differences

Increased High-Density Lipoprotein Cholesterol Levels in Mice With XX Versus XY Sex ChromosomesSignificance

(2015) Jenny C. Link et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

ChIPseeker: an R/Bioconductor package for ChIP peak annotation, comparison and visualization

(2015) Guangchuang Yu et al.   BIOINFORMATICS

A Novel Approach to High-Quality Postmortem Tissue Procurement: The GTEx Project

(2015) Latarsha J. Carithers et al.   BIOPRESERVATION AND BIOBANKING

Genetic Architecture of Insulin Resistance in the Mouse

(2015) Brian W. Parks et al.   Cell Metabolism

Sex differences in diurnal rhythms of food intake in mice caused by gonadal hormones and complement of sex chromosomes

(2015) Xuqi Chen et al.   HORMONES AND BEHAVIOR

Estrogens protect male mice from obesity complications and influence glucocorticoid metabolism

(2015) R S Dakin et al.   INTERNATIONAL JOURNAL OF OBESITY

Fitting Linear Mixed-Effects Models Usinglme4

(2015) Douglas Bates et al.   Journal of Statistical Software

Shaping fat distribution: New insights into the molecular determinants of depot- and sex-dependent adipose biology

(2015) Susan K. Fried et al.   Obesity

Disrupted intricacy of histone H3K4 methylation in neurodevelopmental disorders

(2015) Christina N Vallianatos et al.   Epigenomics

A Novel Approach to High-Quality Postmortem Tissue Procurement: The GTEx Project

(2015) Latarsha J. Carithers et al.   Biopreservation and Biobanking

HTSeq--a Python framework to work with high-throughput sequencing data

(2014) S. Anders et al.   BIOINFORMATICS

Gene-gene and gene-environment interactions detected by transcriptome sequence analysis in twins

(2014) Alfonso Buil et al.   NATURE GENETICS

Variations in body weight, food intake and body composition after long-term high-fat diet feeding in C57BL/6J mice

(2014) Yongbin Yang et al.   Obesity

The role of JAK–STAT signaling in adipose tissue function

(2013) Allison J. Richard et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Enrichr: interactive and collaborative HTML5 gene list enrichment analysis tool

(2013) Edward Y Chen et al.   BMC BIOINFORMATICS

The Genotype-Tissue Expression (GTEx) project

(2013) John Lonsdale et al.   NATURE GENETICS

Transposition of native chromatin for fast and sensitive epigenomic profiling of open chromatin, DNA-binding proteins and nucleosome position

(2013) Jason D Buenrostro et al.   NATURE METHODS

RSeQC: quality control of RNA-seq experiments

(2012) Liguo Wang et al.   BIOINFORMATICS

STAR: ultrafast universal RNA-seq aligner

(2012) Alexander Dobin et al.   BIOINFORMATICS

Role of kruppel-like transcription factors in adipogenesis

(2012) Zeni Wu et al.   DEVELOPMENTAL BIOLOGY

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

Fast gapped-read alignment with Bowtie 2

(2012) Ben Langmead et al.   NATURE METHODS

UTX and UTY Demonstrate Histone Demethylase-Independent Function in Mouse Embryonic Development

(2012) Karl B. Shpargel et al.   PLoS Genetics

The Number of X Chromosomes Causes Sex Differences in Adiposity in Mice

(2012) Xuqi Chen et al.   PLoS Genetics

Escape from X inactivation in mice and humans

(2012) Joel B Berletch et al.   GENOME BIOLOGY

Insulin resistance and metabolic syndrome in prepubertal boys with Klinefelter syndrome

(2011) Martha Z Bardsley et al.   ACTA PAEDIATRICA

Integrative genomics viewer

(2011) James T Robinson et al.   NATURE BIOTECHNOLOGY

A scaling normalization method for differential expression analysis of RNA-seq data

(2010) Mark D Robinson et al.   GENOME BIOLOGY

Resistance to Diet-Induced Obesity in Mice with Synthetic Glyoxylate Shunt

(2009) Jason T. Dean et al.   Cell Metabolism

Sex Differences in High-fat Diet-induced Obesity, Metabolic Alterations and Learning, and Synaptic Plasticity Deficits in Mice

(2009) Ling-Ling Hwang et al.   Obesity

BioGPS: an extensible and customizable portal for querying and organizing gene annotation resources

(2009) Chunlei Wu et al.   GENOME BIOLOGY

What does the “four core genotypes” mouse model tell us about sex differences in the brain and other tissues?

(2008) Arthur P. Arnold et al.   FRONTIERS IN NEUROENDOCRINOLOGY

Model-based Analysis of ChIP-Seq (MACS)

(2008) Yong Zhang et al.   GENOME BIOLOGY

Normal bone mineral content but unfavourable muscle/fat ratio in Klinefelter syndrome

(2007) L Aksglaede et al.   ARCHIVES OF DISEASE IN CHILDHOOD