Targeting a ceramide double bond improves insulin resistance and hepatic steatosis

Could Ceramides Become the New Cholesterol?

(2018) Scott A. Summers   Cell Metabolism

Circulating Sphingolipids, Insulin, HOMA-IR, and HOMA-B: The Strong Heart Family Study

(2018) Rozenn N. Lemaitre et al.   DIABETES

Saturated Fat Is More Metabolically Harmful for the Human Liver Than Unsaturated Fat or Simple Sugars

(2018) Panu K. Luukkonen et al.   DIABETES CARE

Plasma concentrations of molecular lipid species predict long-term clinical outcome in coronary artery disease patients

(2018) Sharda S. Anroedh et al.   JOURNAL OF LIPID RESEARCH

Does This Schlank Make Me Look Fat?

(2018) Bhagirath Chaurasia et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Ceramide Synthase Schlank Is a Transcriptional Regulator Adapting Gene Expression to Energy Requirements

(2018) Mariangela Sociale et al.   Cell Reports

Plasma Dihydroceramides Are Diabetes Susceptibility Biomarker Candidates in Mice and Humans

(2017) Leonore Wigger et al.   Cell Reports

Quantifying rates of glucose production in vivo following an intraperitoneal tracer bolus

(2016) Sheng-Ping Wang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Circulating Ceramides Predict Cardiovascular Outcomes in the Population-Based FINRISK 2002 CohortHighlights

(2016) Aki S. Havulinna et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Adipocyte Ceramides Regulate Subcutaneous Adipose Browning, Inflammation, and Metabolism

(2016) Bhagirath Chaurasia et al.   Cell Metabolism

Plasma ceramides predict cardiovascular death in patients with stable coronary artery disease and acute coronary syndromes beyond LDL-cholesterol

(2016) Reijo Laaksonen et al.   EUROPEAN HEART JOURNAL

Hepatic ceramides dissociate steatosis and insulin resistance in patients with non-alcoholic fatty liver disease

(2016) Panu K. Luukkonen et al.   JOURNAL OF HEPATOLOGY

The enigmatic membrane fatty acid transporter CD36: New insights into fatty acid binding and their effects on uptake of oxidized LDL

(2016) Anthony G. Jay et al.   PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS

Serum sphingolipids: relationships to insulin sensitivity and changes with exercise in humans

(2015) Bryan C. Bergman et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Targeted Induction of Ceramide Degradation Leads to Improved Systemic Metabolism and Reduced Hepatic Steatosis

(2015) Jonathan Y. Xia et al.   Cell Metabolism

Dihydroceramides: From Bit Players to Lead Actors

(2015) Monowarul Mobin Siddique et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ceramides – Lipotoxic Inducers of Metabolic Disorders

(2015) Bhagirath Chaurasia et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Adipocyte SIRT1 knockout promotes PPARγ activity, adipogenesis and insulin sensitivity in chronic-HFD and obesity

(2015) Rafael Mayoral et al.   Molecular Metabolism

Intestinal farnesoid X receptor signaling promotes nonalcoholic fatty liver disease

(2014) Changtao Jiang et al.   JOURNAL OF CLINICAL INVESTIGATION

CD36 Enhances Fatty Acid Uptake by Increasing the Rate of Intracellular Esterification but Not Transport across the Plasma Membrane

(2013) Su Xu et al.   BIOCHEMISTRY

Plasma dihydroceramide species associate with waist circumference in Mexican American families

(2013) Manju Mamtani et al.   Obesity

Plasma Lipid Profiling Shows Similar Associations with Prediabetes and Type 2 Diabetes

(2013) Peter J. Meikle et al.   PLoS One

Plasma sphingolipids are biomarkers of metabolic syndrome in non-human primates maintained on a Western-style diet

(2012) J T Brozinick et al.   INTERNATIONAL JOURNAL OF OBESITY

Transcriptional Control of Adipose Lipid Handling by IRF4

(2011) Jun Eguchi et al.   Cell Metabolism

Ceramides as modulators of cellular and whole-body metabolism

(2011) Benjamin T. Bikman et al.   JOURNAL OF CLINICAL INVESTIGATION

AAV8-Mediated Long-Term Expression of Human LCAT Significantly Improves Lipid Profiles in hCETP;Ldlr+/− Mice

(2011) Zhu Chen et al.   Journal of Cardiovascular Translational Research

Molecular Mechanism for Lateral Lipid Diffusion between the Outer Membrane External Leaflet and a β-Barrel Hydrocarbon Ruler

(2009) M. Adil Khan et al.   BIOCHEMISTRY

Plasma Membrane Subdomain Compartmentalization Contributes to Distinct Mechanisms of Ceramide Action on Insulin Signaling

(2009) C. M. Blouin et al.   DIABETES

Fast Diffusion of Very Long Chain Saturated Fatty Acids across a Bilayer Membrane and Their Rapid Extraction by Cyclodextrins

(2009) Biju K. Pillai et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Fatty acids are rapidly delivered to and extracted from membranes by methyl- -cyclodextrin

(2009) K. Brunaldi et al.   JOURNAL OF LIPID RESEARCH

Targeting of PKCζ and PKB to caveolin-enriched microdomains represents a crucial step underpinning the disruption in PKB-directed signalling by ceramide

(2008) Eric Hajduch et al.   BIOCHEMICAL JOURNAL

Uptake of long chain fatty acids is regulated by dynamic interaction of FAT/CD36 with cholesterol/sphingolipid enriched microdomains (lipid rafts)

(2008) Robert Ehehalt et al.   BMC CELL BIOLOGY

Selective versus Total Insulin Resistance: A Pathogenic Paradox

(2008) Michael S. Brown et al.   Cell Metabolism