Restoring bone marrow niche function rejuvenates aged hematopoietic stem cells by reactivating the DNA Damage Response
出版年份 2023 全文链接
标题
Restoring bone marrow niche function rejuvenates aged hematopoietic stem cells by reactivating the DNA Damage Response
作者
关键词
-
出版物
Nature Communications
Volume 14, Issue 1, Pages -
出版商
Springer Science and Business Media LLC
发表日期
2023-04-11
DOI
10.1038/s41467-023-37783-4
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Niche derived netrin-1 regulates hematopoietic stem cell dormancy via its receptor neogenin-1
- (2021) Simon Renders et al. Nature Communications
- Single-cell RNA-seq reveals a concomitant delay in differentiation and cell cycle of aged hematopoietic stem cells
- (2021) Léonard Hérault et al. BMC BIOLOGY
- DNA damage—how and why we age?
- (2021) Matt Yousefzadeh et al. eLife
- A comprehensive transcriptome signature of murine hematopoietic stem cell aging
- (2021) Arthur Flohr Svendsen et al. BLOOD
- Decline in IGF1 in the bone marrow microenvironment initiates hematopoietic stem cell aging
- (2021) Kira Young et al. Cell Stem Cell
- The central role of DNA damage in the ageing process
- (2021) Björn Schumacher et al. NATURE
- Advances in Management for Older Adults With Hematologic Malignancies
- (2021) Ashley E. Rosko et al. JOURNAL OF CLINICAL ONCOLOGY
- Aged hematopoietic stem cells are refractory to bloodborne systemic rejuvenation interventions
- (2021) Theodore T. Ho et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Chronic activation of endothelial MAPK disrupts hematopoiesis via NFKB dependent inflammatory stress reversible by SCGF
- (2020) Pradeep Ramalingam et al. Nature Communications
- Endothelial mTOR maintains hematopoiesis during aging
- (2020) Pradeep Ramalingam et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Mitochondrial Potentiation Ameliorates Age-Related Heterogeneity in Hematopoietic Stem Cell Function
- (2020) Els Mansell et al. Cell Stem Cell
- Micro-environmental sensing by bone marrow stroma identifies IL-6 and TGFβ1 as regulators of hematopoietic ageing
- (2020) Simona Valletta et al. Nature Communications
- Mitochondrial Stress-Initiated Aberrant Activation of the NLRP3 Inflammasome Regulates the Functional Deterioration of Hematopoietic Stem Cell Aging
- (2019) Hanzhi Luo et al. Cell Reports
- Long-term ex vivo haematopoietic-stem-cell expansion allows nonconditioned transplantation
- (2019) Adam C. Wilkinson et al. NATURE
- Digital expression explorer 2: a repository of uniformly processed RNA sequencing data
- (2019) Mark Ziemann et al. GigaScience
- Neogenin-1 distinguishes between myeloid-biased and balanced Hoxb5+ mouse long-term hematopoietic stem cells
- (2019) Gunsagar S. Gulati et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Microenvironmental contributions to hematopoietic stem cell aging
- (2019) Ya-Hsuan Ho et al. HAEMATOLOGICA
- Global Transcriptomic Profiling of the Bone Marrow Stromal Microenvironment during Postnatal Development, Aging, and Inflammation
- (2019) Patrick M. Helbling et al. Cell Reports
- Nuclear Genomic Instability and Aging
- (2018) Laura J. Niedernhofer et al. Annual Review of Biochemistry
- Adrenergic nerve degeneration in bone marrow drives aging of the hematopoietic stem cell niche
- (2018) Maria Maryanovich et al. NATURE MEDICINE
- Revisiting Netrin-1: One Who Guides (Axons)
- (2018) Nicholas P. Boyer et al. Frontiers in Cellular Neuroscience
- iDEP: an integrated web application for differential expression and pathway analysis of RNA-Seq data
- (2018) Steven Xijin Ge et al. BMC BIOINFORMATICS
- Stem cells: Aging and transcriptional fingerprints
- (2017) Brice E. Keyes et al. JOURNAL OF CELL BIOLOGY
- Endothelial transplantation rejuvenates aged hematopoietic stem cell function
- (2017) Michael G. Poulos et al. JOURNAL OF CLINICAL INVESTIGATION
- Netrins as prophylactic targets in skeletal diseases: A double-edged sword?
- (2017) Kenta Maruyama et al. PHARMACOLOGICAL RESEARCH
- Hematopoietic Stem Cells Count and Remember Self-Renewal Divisions
- (2016) Jeffrey M. Bernitz et al. CELL
- Clearance of senescent cells by ABT263 rejuvenates aged hematopoietic stem cells in mice
- (2015) Jianhui Chang et al. NATURE MEDICINE
- A mitochondrial UPR-mediated metabolic checkpoint regulates hematopoietic stem cell aging
- (2015) M. Mohrin et al. SCIENCE
- Complete Loss of Netrin-1 Results in Embryonic Lethality and Severe Axon Guidance Defects without Increased Neural Cell Death
- (2015) Jenea M. Bin et al. Cell Reports
- Vascular Platform to Define Hematopoietic Stem Cell Factors and Enhance Regenerative Hematopoiesis
- (2015) Michael G. Poulos et al. Stem Cell Reports
- Skewer: a fast and accurate adapter trimmer for next-generation sequencing paired-end reads
- (2014) Hongshan Jiang et al. BMC BIOINFORMATICS
- Leptin Receptor Makes Its Mark on MSCs
- (2014) Yumi Matsuzaki et al. Cell Stem Cell
- Epigenomic Profiling of Young and Aged HSCs Reveals Concerted Changes during Aging that Reinforce Self-Renewal
- (2014) Deqiang Sun et al. Cell Stem Cell
- Quiescent Hematopoietic Stem Cells Accumulate DNA Damage during Aging that Is Repaired upon Entry into Cell Cycle
- (2014) Isabel Beerman et al. Cell Stem Cell
- Leptin-Receptor-Expressing Mesenchymal Stromal Cells Represent the Main Source of Bone Formed by Adult Bone Marrow
- (2014) Bo O. Zhou et al. Cell Stem Cell
- Replication stress is a potent driver of functional decline in ageing haematopoietic stem cells
- (2014) Johanna Flach et al. NATURE
- Stem cell aging: mechanisms, regulators and therapeutic opportunities
- (2014) Juhyun Oh et al. NATURE MEDICINE
- Kraken: A set of tools for quality control and analysis of high-throughput sequence data
- (2013) Matthew P.A. Davis et al. METHODS
- STAR: ultrafast universal RNA-seq aligner
- (2012) Alexander Dobin et al. BIOINFORMATICS
- Cdc42 Activity Regulates Hematopoietic Stem Cell Aging and Rejuvenation
- (2012) Maria Carolina Florian et al. Cell Stem Cell
- Endothelial and perivascular cells maintain haematopoietic stem cells
- (2012) Lei Ding et al. NATURE
- Netrin-1 role in angiogenesis: To be or not to be a pro-angiogenic factor?
- (2011) Marie Castets et al. CELL CYCLE
- edgeR: a Bioconductor package for differential expression analysis of digital gene expression data
- (2009) M. D. Robinson et al. BIOINFORMATICS
- DLL1-mediated Notch activation regulates endothelial identity in mouse fetal arteries
- (2009) I. Sorensen et al. BLOOD
- The Notch Ligands Dll4 and Jagged1 Have Opposing Effects on Angiogenesis
- (2009) Rui Benedito et al. CELL
- Genotoxic Stress Abrogates Renewal of Melanocyte Stem Cells by Triggering Their Differentiation
- (2009) Ken Inomata et al. CELL
- Engraftment and Reconstitution of Hematopoiesis Is Dependent on VEGFR2-Mediated Regeneration of Sinusoidal Endothelial Cells
- (2009) Andrea T. Hooper et al. Cell Stem Cell
- ELDA: Extreme limiting dilution analysis for comparing depleted and enriched populations in stem cell and other assays
- (2009) Yifang Hu et al. JOURNAL OF IMMUNOLOGICAL METHODS
- The DNA-damage response in human biology and disease
- (2009) Stephen P. Jackson et al. NATURE
- DNA Damage, Aging, and Cancer
- (2009) Jan H.J. Hoeijmakers NEW ENGLAND JOURNAL OF MEDICINE
- mTOR Regulation and Therapeutic Rejuvenation of Aging Hematopoietic Stem Cells
- (2009) C. Chen et al. Science Signaling
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now