The angiotensin receptor neprilysin inhibitor LCZ696 attenuates renal fibrosis via ASK1/JNK/p38 MAPK-mediated apoptosis in unilateral ureteral obstruction
出版年份 2023 全文链接
标题
The angiotensin receptor neprilysin inhibitor LCZ696 attenuates renal fibrosis via ASK1/JNK/p38 MAPK-mediated apoptosis in unilateral ureteral obstruction
作者
关键词
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出版物
PLoS One
Volume 18, Issue 6, Pages e0286903
出版商
Public Library of Science (PLoS)
发表日期
2023-06-14
DOI
10.1371/journal.pone.0286903
参考文献
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注意：仅列出部分参考文献，下载原文获取全部文献信息。- Dapagliflozin Alleviates Renal Fibrosis by Inhibiting RIP1-RIP3-MLKL-Mediated Necroinflammation in Unilateral Ureteral Obstruction
- (2022) Mei Ying Xuan et al. Frontiers in Pharmacology
- Combined levosimendan and Sacubitril/Valsartan markedly protected the heart and kidney against cardiorenal syndrome in rat
- (2022) Pei-Hsun Sung et al. BIOMEDICINE & PHARMACOTHERAPY
- Coenzyme Q10 attenuates renal fibrosis by inhibiting RIP1-RIP3-MLKL-mediated necroinflammation via Wnt3α/β-catenin/GSK-3β signaling in unilateral ureteral obstruction
- (2022) Yu Ji Jiang et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- Inhibition of RIP1-RIP3-mediated necroptosis attenuates renal fibrosis via Wnt3α/β-catenin/GSK-3β signaling in unilateral ureteral obstruction
- (2022) Shang Guo Piao et al. PLoS One
- Inhibition of ER stress attenuates kidney injury and apoptosis induced by 3-MCPD via regulating mitochondrial fission/fusion and Ca2+ homeostasis
- (2021) Yujie Zhong et al. CELL BIOLOGY AND TOXICOLOGY
- Redox signaling pathways in unilateral ureteral obstruction (UUO)-induced renal fibrosis
- (2021) Ana Karina Aranda-Rivera et al. FREE RADICAL BIOLOGY AND MEDICINE
- Cardioprotective effects of early intervention with sacubitril/valsartan on pressure overloaded rat hearts
- (2021) Xiaofei Li et al. Scientific Reports
- Transcriptome-Based Network Analysis Reveals Hirudin Potentiates Anti-Renal Fibrosis Efficacy in UUO Rats
- (2021) Hang-Xing Yu et al. Frontiers in Pharmacology
- Entresto protected the cardiomyocytes and preserved heart function in cardiorenal syndrome rat fed with high-protein diet through regulating the oxidative stress and Mfn2-mediated mitochondrial functional integrity
- (2021) Jui-Ning Yeh et al. BIOMEDICINE & PHARMACOTHERAPY
- Exogenous pancreatic kininogenase protects against renal fibrosis in rat model of unilateral ureteral obstruction
- (2020) Ji-zhe Jin et al. ACTA PHARMACOLOGICA SINICA
- A novel protective role of sacubitril/valsartan in cyclophosphamide induced lung injury in rats: impact of miRNA-150-3p on NF-κB/MAPK signaling trajectories
- (2020) Ghada A. Abdel-Latif et al. Scientific Reports
- LCZ696 mitigates diabetic-induced nephropathy through inhibiting oxidative stress, NF-κB mediated inflammation and glomerulosclerosis in rats
- (2020) Mohamed Mohany et al. PeerJ
- Mitochondrial dysfunction and endoplasmic reticulum stress in the promotion of fibrosis in obstructive nephropathy induced by unilateral ureteral obstruction
- (2020) Elena Martínez‐Klimova et al. BIOFACTORS
- Effects of sacubitril/valsartan in patients with heart failure and chronic kidney disease: A meta-analysis
- (2020) Huaning Kang et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Inhibition of apoptosis signal-regulating kinase 1 mitigates the pathogenesis of human immunodeficiency virus–associated nephropathy
- (2020) Anqun Chen et al. NEPHROLOGY DIALYSIS TRANSPLANTATION
- L-carnitine treatment attenuates renal tubulointerstitial fibrosis induced by unilateral ureteral obstruction
- (2020) Hai Yan Zhao et al. KOREAN JOURNAL OF INTERNAL MEDICINE
- Organelle crosstalk in the kidney
- (2019) Tsuyoshi Inoue et al. KIDNEY INTERNATIONAL
- The combination of a neprilysin inhibitor (sacubitril) and angiotensin-II receptor blocker (valsartan) attenuates glomerular and tubular injury in the Zucker Obese rat
- (2019) Javad Habibi et al. Cardiovascular Diabetology
- Pharmacological levels of hydrogen sulfide inhibit oxidative cell injury through regulating the redox state of thioredoxin
- (2019) Zhimin Mao et al. FREE RADICAL BIOLOGY AND MEDICINE
- LCZ696, an angiotensin receptor-neprilysin inhibitor, ameliorates diabetic cardiomyopathy by inhibiting inflammation, oxidative stress and apoptosis
- (2019) Qing Ge et al. EXPERIMENTAL BIOLOGY AND MEDICINE
- Angiotensin–Neprilysin Inhibition in Heart Failure with Preserved Ejection Fraction
- (2019) Scott D. Solomon et al. NEW ENGLAND JOURNAL OF MEDICINE
- Angiotensin–neprilysin inhibition confers renoprotection in rats with diabetes and hypertension by limiting podocyte injury
- (2019) Estrellita Uijl et al. JOURNAL OF HYPERTENSION
- ASK1 inhibitor treatment suppresses p38/JNK signalling with reduced kidney inflammation and fibrosis in rat crescentic glomerulonephritis
- (2018) Liv A. Amos et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Effect of neprilysin inhibition on renal function in patients with type 2 diabetes and chronic heart failure who are receiving target doses of inhibitors of the renin-angiotensin system: a secondary analysis of the PARADIGM-HF trial
- (2018) Milton Packer et al. Lancet Diabetes & Endocrinology
- Renal Effects and Associated Outcomes During Angiotensin-Neprilysin Inhibition in Heart Failure
- (2018) Kevin Damman et al. JACC-Heart Failure
- ASK1 contributes to fibrosis and dysfunction in models of kidney disease
- (2018) John T. Liles et al. JOURNAL OF CLINICAL INVESTIGATION
- LCZ696 improves cardiac function via alleviating Drp1-mediated mitochondrial dysfunction in mice with doxorubicin-induced dilated cardiomyopathy
- (2017) Yan Xia et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- Mitogen-Activated Protein Kinases and Hypoxic/Ischemic Nephropathy
- (2016) Fengbao Luo et al. CELLULAR PHYSIOLOGY AND BIOCHEMISTRY
- Combined Angiotensin Receptor Antagonism and Neprilysin Inhibition
- (2016) Scott A. Hubers et al. CIRCULATION
- Neprilysin inhibition in chronic kidney disease
- (2014) P. Judge et al. NEPHROLOGY DIALYSIS TRANSPLANTATION
- The Thioredoxin System as a Therapeutic Target in Human Health and Disease
- (2012) Dler Faieeq Darweesh Mahmood et al. ANTIOXIDANTS & REDOX SIGNALING
- Hypertension Awareness, Treatment, and Control in Adults With CKD: Results From the Chronic Renal Insufficiency Cohort (CRIC) Study
- (2009) Paul Muntner et al. AMERICAN JOURNAL OF KIDNEY DISEASES
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