Coenzyme Q10 attenuates renal fibrosis by inhibiting RIP1-RIP3-MLKL-mediated necroinflammation via Wnt3α/β-catenin/GSK-3β signaling in unilateral ureteral obstruction

Fluorofenidone Alleviates Renal Fibrosis by Inhibiting Necroptosis Through RIPK3/MLKL Pathway

(2021) Qin Dai et al.   Frontiers in Pharmacology

Water-soluble coenzyme Q10 provides better protection than lipid-soluble coenzyme Q10 in a rat model of chronic tacrolimus nephropathy

(2021) Sheng Cui et al.   KOREAN JOURNAL OF INTERNAL MEDICINE

Indoleamine-2,3-Dioxygenase Activates Wnt/β-Catenin Inducing Kidney Fibrosis after Acute Kidney Injury

(2021) Binbin Pan et al.   GERONTOLOGY

Tanshinone IIA attenuates high glucose-induced epithelial-to-mesenchymal transition in HK-2 cells through VDR/Wnt/β-catenin signaling pathway

(2021) Jingyi Zeng et al.   FOLIA HISTOCHEMICA ET CYTOBIOLOGICA

Coenzyme Q10 Activates the Antioxidant Machinery and Inhibits the Inflammatory and Apoptotic Cascades Against Lead Acetate-Induced Renal Injury in Rats

(2020) Wafa A. AL-Megrin et al.   Frontiers in Physiology

Exogenous pancreatic kininogenase protects against renal fibrosis in rat model of unilateral ureteral obstruction

(2020) Ji-zhe Jin et al.   ACTA PHARMACOLOGICA SINICA

L-Carnitine protects against tacrolimus-induced renal injury by attenuating programmed cell death via PI3K/AKT/PTEN signaling

(2020) Hai-lan Zheng et al.   ACTA PHARMACOLOGICA SINICA

Coenzyme Q10 Supplementation for the Reduction of Oxidative Stress: Clinical Implications in the Treatment of Chronic Diseases

(2020) Francisco Miguel Gutierrez-Mariscal et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

L-carnitine treatment attenuates renal tubulointerstitial fibrosis induced by unilateral ureteral obstruction

(2020) Hai Yan Zhao et al.   KOREAN JOURNAL OF INTERNAL MEDICINE

Withaferin A protects against endoplasmic reticulum stress-associated apoptosis, inflammation, and fibrosis in the kidney of a mouse model of unilateral ureteral obstruction

(2020) Chang-Mu Chen et al.   PHYTOMEDICINE

CoQ10 ameliorates mitochondrial dysfunction in diabetic nephropathy through mitophagy

(2019) Jia Sun et al.   JOURNAL OF ENDOCRINOLOGY

Pathogenesis of lupus nephritis: RIP3 dependent necroptosis and NLRP3 inflammasome activation

(2019) Chaohuan Guo et al.   JOURNAL OF AUTOIMMUNITY

Correlation between circulating fibrocytes and dermal thickness in limited cutaneous systemic sclerosis patients: a pilot study

(2019) Barbara Ruaro et al.   RHEUMATOLOGY INTERNATIONAL

Wnt/β‐catenin/RAS signaling mediates age‐related renal fibrosis and is associated with mitochondrial dysfunction

(2019) Jinhua Miao et al.   AGING CELL

Scintigraphic evaluation of renoprotective effects of coenzyme Q10 in a rat renal ischemia-reperfusion injury

(2019) Aylin Akbulut et al.   NUCLEAR MEDICINE COMMUNICATIONS

Necrostatin-1 attenuates renal ischemia/reperfusion injury by inhibiting necroptosis, oxidative stress, and inflammation via mediation of HIF-1α/miR-26a/TRPC6/PARP1 signaling

(2019) Bingbing Shen et al.   Molecular Therapy-Nucleic Acids

Unilateral Ureteral Obstruction as a Model to Investigate Fibrosis-Attenuating Treatments

(2019) Elena Martínez-Klimova et al.   Biomolecules

CKD in China: Evolving Spectrum and Public Health Implications

(2019) Chao Yang et al.   AMERICAN JOURNAL OF KIDNEY DISEASES

Coenzyme Q10 alleviates tacrolimus-induced mitochondrial dysfunction in kidney

(2019) Ji Hyun Yu et al.   FASEB JOURNAL

Coenzyme Q 10 deficiencies: pathways in yeast and humans

(2018) Agape M. Awad et al.   Essays in Biochemistry

Necrostatin-1 Attenuates Cisplatin-Induced Nephrotoxicity Through Suppression of Apoptosis and Oxidative Stress and Retains Klotho Expression

(2018) Yichun Ning et al.   Frontiers in Pharmacology

RIPK3-MLKL-mediated necroinflammation contributes to AKI progression to CKD

(2018) Hui Chen et al.   Cell Death & Disease

Forecasting life expectancy, years of life lost, and all-cause and cause-specific mortality for 250 causes of death: reference and alternative scenarios for 2016–40 for 195 countries and territories

(2018) Kyle J Foreman et al.   LANCET

The hallmarks of mitochondrial dysfunction in chronic kidney disease

(2017) Daniel L. Galvan et al.   KIDNEY INTERNATIONAL

Coenzyme Q10 protects renal proximal tubule cells against nicotine-induced apoptosis through induction of p66shc-dependent antioxidant responses

(2016) Istvan Arany et al.   APOPTOSIS

Diagnosis, Treatment, and Prevention of Hemodialysis Emergencies

(2016) Manish Saha et al.   Clinical Journal of the American Society of Nephrology

Effect of concomitant administration of coenzyme Q10 with sitagliptin on experimentally induced diabetic nephropathy in rats

(2016) Rajesh Maheshwari et al.   RENAL FAILURE

Transforming growth factor beta (TGF-β) isoforms in wound healing and fibrosis

(2016) Michael K. Lichtman et al.   WOUND REPAIR AND REGENERATION

HuangQi Decoction Improves Renal Tubulointerstitial Fibrosis in Mice by Inhibiting the Up-Regulation of Wnt/β-Catenin Signaling Pathway

(2015) Ming-Qian Jiang et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Necroinflammation in Kidney Disease

(2015) S. R. Mulay et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Chronic kidney disease: global dimension and perspectives

(2013) Vivekanand Jha et al.   LANCET

Primary and secondary coenzyme Q10 deficiency: the role of therapeutic supplementation

(2013) Marnie Potgieter et al.   NUTRITION REVIEWS

Inhibition of oxidative stress by coenzyme Q10 increases mitochondrial mass and improves bioenergetic function in optic nerve head astrocytes

(2013) Y H Noh et al.   Cell Death & Disease