Knockout of protein phosphatase 1 in Leishmania major reveals its role during RNA polymerase II transcription termination

Localization of Epigenetic Markers in Leishmania Chromatin

(2022) Jacquelyn R. McDonald et al.   Pathogens

Genetic Interaction Between Site-Specific Epigenetic Marks and Roles of H4v in Transcription Termination in Trypanosoma brucei

(2021) Hee-Sook Kim   Frontiers in Cell and Developmental Biology

Identification of a novel base J binding protein complex involved in RNA polymerase II transcription termination in trypanosomes

(2020) Rudo Kieft et al.   PLoS Genetics

ASPP proteins discriminate between PP1 catalytic subunits through their SH3 domain and the PP1 C-tail

(2019) M. Teresa Bertran et al.   Nature Communications

PP1 and PP2A Use Opposite Phospho-dependencies to Control Distinct Processes at the Kinetochore

(2019) Richard J. Smith et al.   Cell Reports

Control of RNA Pol II Speed by PNUTS-PP1 and Spt5 Dephosphorylation Facilitates Termination by a “Sitting Duck Torpedo” Mechanism

(2019) Michael A. Cortazar et al.   MOLECULAR CELL

Protein Serine/Threonine Phosphatases: Keys to Unlocking Regulators and Substrates

(2018) David L. Brautigan et al.   Annual Review of Biochemistry

OUP accepted manuscript

(2018)   BIOINFORMATICS

Overexpression of PP1–NIPP1 limits the capacity of cells to repair DNA double-strand breaks

(2018) Claudia Winkler et al.   JOURNAL OF CELL SCIENCE

A Cdk9–PP1 switch regulates the elongation–termination transition of RNA polymerase II

(2018) Pabitra K. Parua et al.   NATURE

Nuclear Phosphatidylinositol 5-Phosphatase Is Essential for Allelic Exclusion of Variant Surface Glycoprotein Genes in Trypanosomes

(2018) Igor Cestari et al.   MOLECULAR AND CELLULAR BIOLOGY

Elongation/Termination Factor Exchange Mediated by PP1 Phosphatase Orchestrates Transcription Termination

(2018) Tea Kecman et al.   Cell Reports

A DiCre recombinase-based system for inducible expression in Leishmania major

(2017) Renato E.R.S. Santos et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

The code and beyond: transcription regulation by the RNA polymerase II carboxy-terminal domain

(2017) Kevin M. Harlen et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

An RNA polymerase II-associated TFIIF-like complex is indispensable for SL RNA gene transcription in Trypanosoma brucei

(2017) Ankita Srivastava et al.   NUCLEIC ACIDS RESEARCH

An essential domain of an early-diverged RNA polymerase II functions to accurately decode a primitive chromatin landscape

(2017) Anish Das et al.   NUCLEIC ACIDS RESEARCH

TrypTag.org: A Trypanosome Genome-wide Protein Localisation Resource

(2017) Samuel Dean et al.   TRENDS IN PARASITOLOGY

A CRISPR Cas9 high-throughput genome editing toolkit for kinetoplastids

(2017) Tom Beneke et al.   Royal Society Open Science

Co-transcriptional splicing and the CTD code

(2016) Noélia Custódio et al.   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

A Conserved Motif Provides Binding Specificity to the PP2A-B56 Phosphatase

(2016) Emil Peter Thrane Hertz et al.   MOLECULAR CELL

Conditional gene deletion with DiCre demonstrates an essential role for CRK3 inLeishmania mexicanacell cycle regulation

(2016) Samuel M. Duncan et al.   MOLECULAR MICROBIOLOGY

Base J represses genes at the end of polycistronic gene clusters inLeishmania majorby promoting RNAP II termination

(2016) David L. Reynolds et al.   MOLECULAR MICROBIOLOGY

Base J and H3.V Regulate Transcriptional Termination in Trypanosoma brucei

(2016) Danae Schulz et al.   PLoS Genetics

Histone H3 Variant Regulates RNA Polymerase II Transcription Termination and Dual Strand Transcription of siRNA Loci in Trypanosoma brucei

(2016) David Reynolds et al.   PLoS Genetics

Transcription of Mammalian cis-Regulatory Elements Is Restrained by Actively Enforced Early Termination

(2015) Liv M.I. Austenaa et al.   MOLECULAR CELL

Effects of Transcription Elongation Rate and Xrn2 Exonuclease Activity on RNA Polymerase II Termination Suggest Widespread Kinetic Competition

(2015) Nova Fong et al.   MOLECULAR CELL

Identification of the Glucosyltransferase That Converts Hydroxymethyluracil to Base J in the Trypanosomatid Genome

(2014) Whitney Bullard et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Tb927.10.6900 encodes the glucosyltransferase involved in synthesis of base J in Trypanosoma brucei

(2014) Aarthi Sekar et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

RNA polymerase II termination involves C-terminal-domain tyrosine dephosphorylation by CPF subunit Glc7

(2014) Amelie Schreieck et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Regulation of transcription termination by glucosylated hydroxymethyluracil, base J, in Leishmania major and Trypanosoma brucei

(2014) D. Reynolds et al.   NUCLEIC ACIDS RESEARCH

deepTools: a flexible platform for exploring deep-sequencing data

(2014) Fidel Ramírez et al.   NUCLEIC ACIDS RESEARCH

featureCounts: an efficient general purpose program for assigning sequence reads to genomic features

(2013) Y. Liao et al.   BIOINFORMATICS

Global Quantitative SILAC Phosphoproteomics Reveals Differential Phosphorylation Is Widespread between the Procyclic and Bloodstream Form Lifecycle Stages of Trypanosoma brucei

(2013) Michael D. Urbaniak et al.   JOURNAL OF PROTEOME RESEARCH

Trypanosome cdc2-Related Kinase 9 Controls Spliced Leader RNA cap4 Methylation and Phosphorylation of RNA Polymerase II Subunit RPB1

(2013) N. Badjatia et al.   MOLECULAR AND CELLULAR BIOLOGY

Differential Localization of the Two T. brucei Poly(A) Binding Proteins to the Nucleus and RNP Granules Suggests Binding to Distinct mRNA Pools

(2013) Susanne Kramer et al.   PLoS One

PNUTS/PP1 Regulates RNAPII-Mediated Gene Expression and Is Necessary for Developmental Growth

(2013) Anita Ciurciu et al.   PLoS Genetics

Molecular mechanisms underlying the interaction of protein phosphatase-1c with ASPP proteins

(2012) Tamara D. Skene-Arnold et al.   BIOCHEMICAL JOURNAL

Glucosylated Hydroxymethyluracil, DNA Base J, Prevents Transcriptional Readthrough in Leishmania

(2012) Henri G.A.M. van Luenen et al.   CELL

The RNA polymerase II CTD coordinates transcription and RNA processing

(2012) J.-P. Hsin et al.   GENES & DEVELOPMENT

JBP1 and JBP2 Proteins Are Fe2+/2-Oxoglutarate-dependent Dioxygenases Regulating Hydroxylation of Thymidine Residues in Trypanosome DNA

(2012) Laura J. Cliffe et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Fast gapped-read alignment with Bowtie 2

(2012) Ben Langmead et al.   NATURE METHODS

Prediction of novel families of enzymes involved in oxidative and other complex modifications of bases in nucleic acids

(2011) Lakshminarayan M. Iyer et al.   CELL CYCLE

The structural basis for recognition of base J containing DNA by a novel DNA binding domain in JBP1

(2011) Tatjana Heidebrecht et al.   NUCLEIC ACIDS RESEARCH

Functional Characterization of Three Leishmania Poly(A) Binding Protein Homologues with Distinct Binding Properties to RNA and Protein Partners

(2010) Tamara D. da Costa Lima et al.   EUKARYOTIC CELL

Identification and Characterization of a Novel Human PP1 Phosphatase Complex

(2010) Jeong-Heon Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mass spectrometry and biochemical analysis of RNA polymerase II: targeting by protein phosphatase-1

(2010) Marina Jerebtsova et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Two thymidine hydroxylases differentially regulate the formation of glucosylated DNA at regions flanking polymerase II polycistronic transcription units throughout the genome of Trypanosoma brucei

(2010) Laura J. Cliffe et al.   NUCLEIC ACIDS RESEARCH

The Transcriptome of the Human Pathogen Trypanosoma brucei at Single-Nucleotide Resolution

(2010) Nikolay G. Kolev et al.   PLoS Pathogens

The Sequence Alignment/Map format and SAMtools

(2009) H. Li et al.   BIOINFORMATICS

Four histone variants mark the boundaries of polycistronic transcription units in Trypanosoma brucei

(2009) T. N. Siegel et al.   GENES & DEVELOPMENT

The Phosphoproteome of Bloodstream FormTrypanosoma brucei, Causative Agent of African Sleeping Sickness

(2009) Isabelle R. E. Nett et al.   MOLECULAR & CELLULAR PROTEOMICS

Progression through the RNA Polymerase II CTD Cycle

(2009) Stephen Buratowski   MOLECULAR CELL

JBP1 and JBP2 are two distinct thymidine hydroxylases involved in J biosynthesis in genomic DNA of African trypanosomes

(2009) L. J. Cliffe et al.   NUCLEIC ACIDS RESEARCH

The Non-Canonical CTD of RNAP-II Is Essential for Productive RNA Synthesis in Trypanosoma brucei

(2009) Anish Das et al.   PLoS One

Conversion of 5-Methylcytosine to 5-Hydroxymethylcytosine in Mammalian DNA by MLL Partner TET1

(2009) M. Tahiliani et al.   SCIENCE

Active transcription and ultrastructural changes during Trypanosoma cruzi metacyclogenesis

(2008) Ludmila R.P. Ferreira et al.   ANAIS DA ACADEMIA BRASILEIRA DE CIENCIAS

Base J: Discovery, Biosynthesis, and Possible Functions

(2008) Piet Borst et al.   Annual Review of Microbiology

Histone Acetylation and Methylation at Sites Initiating Divergent Polycistronic Transcription inTrypanosoma cruzi

(2008) Patricia Respuela et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Glc7 Phosphatase Subunit of the Cleavage and Polyadenylation Factor Is Essential for Transcription Termination on snoRNA Genes

(2008) Eduard Nedea et al.   MOLECULAR CELL