Base J represses genes at the end of polycistronic gene clusters inLeishmania majorby promoting RNAP II termination

Base J and H3.V Regulate Transcriptional Termination in Trypanosoma brucei

(2016) Danae Schulz et al.   PLoS Genetics

Histone H3 Variant Regulates RNA Polymerase II Transcription Termination and Dual Strand Transcription of siRNA Loci in Trypanosoma brucei

(2016) David Reynolds et al.   PLoS Genetics

Transcriptomic profiling of gene expression and RNA processing duringLeishmania majordifferentiation

(2015) Laura A. L. Dillon et al.   NUCLEIC ACIDS RESEARCH

Identification of the Glucosyltransferase That Converts Hydroxymethyluracil to Base J in the Trypanosomatid Genome

(2014) Whitney Bullard et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Tb927.10.6900 encodes the glucosyltransferase involved in synthesis of base J in Trypanosoma brucei

(2014) Aarthi Sekar et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

Regulation of transcription termination by glucosylated hydroxymethyluracil, base J, in Leishmania major and Trypanosoma brucei

(2014) D. Reynolds et al.   NUCLEIC ACIDS RESEARCH

Kinetoplastid-specific histone variant functions are conserved in Leishmania major

(2013) Britta A. Anderson et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

Comparative transcriptome analysis of small noncoding RNAs in different stages of Trypanosoma brucei

(2013) L.-L. Zheng et al.   RNA

Small interfering RNA-producing loci in the ancient parasitic eukaryote Trypanosoma brucei

(2012) Christian Tschudi et al.   BMC GENOMICS

Glucosylated Hydroxymethyluracil, DNA Base J, Prevents Transcriptional Readthrough in Leishmania

(2012) Henri G.A.M. van Luenen et al.   CELL

JBP1 and JBP2 Proteins Are Fe2+/2-Oxoglutarate-dependent Dioxygenases Regulating Hydroxylation of Thymidine Residues in Trypanosome DNA

(2012) Laura J. Cliffe et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Differential analysis of gene regulation at transcript resolution with RNA-seq

(2012) Cole Trapnell et al.   NATURE BIOTECHNOLOGY

Prediction of novel families of enzymes involved in oxidative and other complex modifications of bases in nucleic acids

(2011) Lakshminarayan M. Iyer et al.   CELL CYCLE

Epigenetic Regulation of Polymerase II Transcription Initiation in Trypanosoma cruzi: Modulation of Nucleosome Abundance, Histone Modification, and Polymerase Occupancy by O-Linked Thymine DNA Glucosylation

(2011) Dilrukshi Ekanayake et al.   EUKARYOTIC CELL

Epigenetic Regulation of Transcription and Virulence in Trypanosoma cruzi by O-Linked Thymine Glucosylation of DNA

(2011) D. K. Ekanayake et al.   MOLECULAR AND CELLULAR BIOLOGY

Two thymidine hydroxylases differentially regulate the formation of glucosylated DNA at regions flanking polymerase II polycistronic transcription units throughout the genome of Trypanosoma brucei

(2010) Laura J. Cliffe et al.   NUCLEIC ACIDS RESEARCH

The Transcriptome of the Human Pathogen Trypanosoma brucei at Single-Nucleotide Resolution

(2010) Nikolay G. Kolev et al.   PLoS Pathogens

Histone acetylations mark origins of polycistronic transcription in Leishmania major

(2009) Sean Thomas et al.   BMC GENOMICS

Four histone variants mark the boundaries of polycistronic transcription units in Trypanosoma brucei

(2009) T. N. Siegel et al.   GENES & DEVELOPMENT

JBP1 and JBP2 are two distinct thymidine hydroxylases involved in J biosynthesis in genomic DNA of African trypanosomes

(2009) L. J. Cliffe et al.   NUCLEIC ACIDS RESEARCH

Conversion of 5-Methylcytosine to 5-Hydroxymethylcytosine in Mammalian DNA by MLL Partner TET1

(2009) M. Tahiliani et al.   SCIENCE

Base J: Discovery, Biosynthesis, and Possible Functions

(2008) Piet Borst et al.   Annual Review of Microbiology

Histone Acetylation and Methylation at Sites Initiating Divergent Polycistronic Transcription inTrypanosoma cruzi

(2008) Patricia Respuela et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Evidence that J-binding protein 2 is a thymidine hydroxylase catalyzing the first step in the biosynthesis of DNA base J

(2008) Saara Vainio et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY